Pseudo-Tumoral Cutaneous Leishmaniasis

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Abstract

A 53-year-old man from a rural area in Tunisia presented with a 2 month history of asymptomatic and persistent vegetating lesion on the dorsal aspect of the right ankle (Figure 1). Physical examination showed a 15 x 6 cm vegetating and pseudo-tumoral lesion with a papillomatous aspect and large ulceration on surface, a soft moist consistency and an indurated base (Figure 2). The rest of the examination was unremarkable. Optical examination of the smears (taken from two sites), after May–Grünwald–Giemsa staining, revealed amastigote forms of the leishmania parasite. Polymerase-chain-reaction (PCR) assay identified Leishmania Major (L. major). The diagnosis of pseudo-tumoral cutaneous leishmaniasis (CL) was confirmed. The patient was treated with meglumine antimoniate intramuscular (60 mg/kg/day) during three weeks. There was a modest and partial response to treatment. Short Communication Open Access American Research Journal of Dermatology ISSN: 2642-2980 Volume 1, Issue 1, pp: 1-3
假性肿瘤皮肤利什曼病
一名来自突尼斯农村地区的53岁男性患者,右脚踝背部有2个月的无症状持续性植物性病变病史(图1)。体格检查显示为15 x 6厘米的植物性假性肿瘤病变,有乳头状瘤样病变,表面有大溃疡,软性湿润,基底硬化(图2)。其余检查无明显变化。在may - gr nwald - giemsa染色后,对(从两个地点采集的)涂片进行光学检查,发现利什曼原虫的无鞭毛体形式。聚合酶链反应(PCR)鉴定了利什曼原虫(L. Major)。确诊为假性肿瘤性皮肤利什曼病(CL)。患者接受肌注(60mg /kg/天)三周。对治疗有适度和部分的反应。短通信开放获取美国皮肤病学研究杂志ISSN: 2642-2980卷1,第1期,pp: 1-3
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