HANDPub Date : 2026-11-01Epub Date: 2026-04-23DOI: 10.1177/15589447261441330
Nav La, Schawanya K Rattanapitoon, Patpicha Arunsan, Nathkapach K Rattanapitoon
{"title":"Cannabis-Related Disorders After CTR: A Diagnostic Signal Hidden in Plain Sight.","authors":"Nav La, Schawanya K Rattanapitoon, Patpicha Arunsan, Nathkapach K Rattanapitoon","doi":"10.1177/15589447261441330","DOIUrl":"10.1177/15589447261441330","url":null,"abstract":"","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"1748-1749"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13109244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147769878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HANDPub Date : 2026-11-01Epub Date: 2026-08-04DOI: 10.1177/15589447261469602
Nirbhay S Jain, Kurt Weiss, Dana E Bregman
{"title":"Reconstruction of a Base of Fifth Metacarpal Tumor Using the Dubert Procedure: A Case Report.","authors":"Nirbhay S Jain, Kurt Weiss, Dana E Bregman","doi":"10.1177/15589447261469602","DOIUrl":"10.1177/15589447261469602","url":null,"abstract":"<p><p>A 63-year-old right-hand-dominant man was referred for reconstruction following intralesional resection of a myopericytic neoplasm of the base of the left fifth metacarpal. He experienced multiple local recurrences and following serial curettage and placement of calcium phosphate graft, he eventually underwent resection of the base of the fifth metacarpal. To prevent subsidence of the fifth metacarpal while maintaining motion, the fifth metacarpal shaft was fused to the fourth metacarpal shaft with autogenous bone graft. The metacarpals fused, with good motion and grip strengths at the 6-month follow-up visit. This demonstrates that stability can be maintained without sacrificing motion after tumor excision.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"NP1-NP5"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13442936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148673662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HANDPub Date : 2026-11-01Epub Date: 2025-12-31DOI: 10.1177/15589447251406719
Tarek Abdalla El-Gammal, Amr El-Sayed, Mohamed Adel Abdeen
{"title":"Nerve Transfer Versus Tendon Transfer for Isolated Radial Nerve Palsy.","authors":"Tarek Abdalla El-Gammal, Amr El-Sayed, Mohamed Adel Abdeen","doi":"10.1177/15589447251406719","DOIUrl":"10.1177/15589447251406719","url":null,"abstract":"<p><strong>Background: </strong>Reconstructive options for high radial nerve injuries include tendon transfer (TT) and nerve transfer (NT), each with distinct advantages and limitations. This prospective, randomized clinical trial compared the outcomes of TT and NT in 21 patients with isolated radial nerve injuries.</p><p><strong>Methods: </strong>Patients were randomly assigned to the NT group (11 patients) or the TT group (10 patients). Nerve transfer involved transferring the distal anterior interosseous nerve to the extensor carpi radialis brevis motor branch and the flexor carpi radialis motor branch to the posterior interosseous nerve. Tendon transfer used the Boyes tendon transfer technique.</p><p><strong>Results: </strong>At an average follow-up of 20 months for NT and 15 months for TT, NT resulted in significantly better wrist flexion (51° vs 27°), wrist extension (54° vs 34°), metacarpophalangeal hyperextension (15° vs 8°), and thumb radial abduction (44° vs 37°). Nerve transfer also resulted in significantly higher muscle power grades for finger and thumb extension, with higher proportions of patients achieving grades M4+ and M5. Both groups showed significant improvements in Disabilities of the Arm, Shoulder, and Hand scores and grip strength, but with no significant differences between both groups. Tendon transfer offered faster functional recovery (4.30 ± 1.49 months) compared with NT (5.72 ± 1.34 months).</p><p><strong>Conclusions: </strong>Nerve transfer provided better long-term muscle strength and range of motion, while TT allowed quicker rehabilitation. The choice between NT and TT should consider individual patient factors, balancing early functional recovery with long-term outcomes. Further studies with larger cohorts are recommended to validate these results and refine treatment guidelines.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"1597-1604"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12756058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145862869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HANDPub Date : 2026-11-01Epub Date: 2025-12-31DOI: 10.1177/15589447251404972
Joydeep Baidya, Evan Johnson, Joshua Pang, Arjun Guthal, Pedro K Beredjiklian, Daniel J Fletcher
{"title":"Validation of a Quick Carpal Tunnel Syndrome-6 Questionnaire as a Diagnostic Tool for Carpal Tunnel Syndrome.","authors":"Joydeep Baidya, Evan Johnson, Joshua Pang, Arjun Guthal, Pedro K Beredjiklian, Daniel J Fletcher","doi":"10.1177/15589447251404972","DOIUrl":"10.1177/15589447251404972","url":null,"abstract":"<p><strong>Background: </strong>Carpal tunnel syndrome is common, and carpal tunnel syndrome-6 (CTS-6) is a validated diagnostic tool; however, its weighted scoring limits rapid use. We evaluated a simplified quick carpal tunnel syndrome-6 (QCTS-6) for diagnostic accuracy.</p><p><strong>Methods: </strong>Carpal tunnel releases performed at a tertiary care center (January 2017-August 2024) were retrospectively identified. Preoperative presence or absence of the components of the CTS-6 were reviewed and assigned the corresponding number of points. For the QCTS-6 scoring system, 0 or 1 point was assigned for a total score out of 6. Preoperative electromyography (EMG)/nerve conduction study (NCS) results were collected when available. Descriptive statistics, Spearman's Rho correlations, and diagnostic ratio tests were performed.</p><p><strong>Results: </strong>A total of 1143 patients met the inclusion criteria. There was a strong positive relationship between the CTS-6 and QCTS-6 scores for the overall cohort (<i>r</i> = 0.976). Patients with QCTS-6 score of 3 or more exhibited the presence of all questionnaire components and severe EMG/NCS findings at higher rates, with 98.2% of them having CTS-6 scores greater than 12. Diagnostic ratio testing identified numbness in the median nerve territory, nocturnal numbness, and loss of 2-point discrimination as the most balanced predictive factors.</p><p><strong>Conclusions: </strong>The QCTS-6 scoring system can be a valid alternative to the traditional CTS-6. Owing to its uniform scoring, it can allow for efficient workup without necessitating EMG/NCS. A score of 3 or more may serve as a sensitive cutoff for carpal tunnel syndrome.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"1614-1620"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12756054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145862829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HANDPub Date : 2026-11-01Epub Date: 2026-01-18DOI: 10.1177/15589447251409355
Joydeep Baidya, Nicholas B Pohl, Meghan Schilken, Steven Yi, Stacey Mavridis, Rachel Huang, Christopher M Jones, Daniel J Fletcher
{"title":"Olecranon Fracture Repair: A Comparative Analysis of 4 Surgical Techniques.","authors":"Joydeep Baidya, Nicholas B Pohl, Meghan Schilken, Steven Yi, Stacey Mavridis, Rachel Huang, Christopher M Jones, Daniel J Fletcher","doi":"10.1177/15589447251409355","DOIUrl":"10.1177/15589447251409355","url":null,"abstract":"<p><strong>Background: </strong>Olecranon fractures are common injuries and may be indicated for open reduction and internal fixation (ORIF). Surgical techniques include plates and screws, intramedullary screw, Kirschner wire with tension band (KWTB), and all-suture fixation. The purpose of this study was to compare surgical and patient-reported outcomes between these fixation techniques.</p><p><strong>Methods: </strong>Adult patients who underwent surgery were retrospectively queried (January 2016-December 2020). Demographics, comorbidities, fracture characteristics, surgical details, elbow range of motion (ROM), incidence and time to radiographic healing, reoperations, complications, and patient-reported outcomes were collected.</p><p><strong>Results: </strong>A total of 426 patients met inclusion criteria (plates and screws: 315, intramedullary screw: 27, KWTB: 64, all-suture: 20). Comminuted fractures were predominantly managed using ORIF with plates and screws (45.4%; <i>P</i> < .001). In the postoperative period, KWTB patients experienced hardware loosening (7.81%; <i>P</i> = .049), reoperation (25.0%; <i>P</i> = .031), and delayed radiographic healing (129 ± 226 days; <i>P</i> = .013) at higher rates. Logistic regression demonstrated that comminuted fractures were less likely to be repaired using intramedullary screw fixation or KWTB in comparison with ORIF with plates and screws. Linear regression also found that intramedullary screw fixation was associated with a significant decrease in postoperative elbow extension ROM.</p><p><strong>Conclusions: </strong>This study found that the 4 surgical techniques for olecranon fracture fixation provided favorable postoperative and patient-reported outcomes while identifying differences in tension band type, fracture characteristics, and complications that may influence surgical decision-making. The otherwise comparable outcomes suggest that surgeons may repair olecranon fractures using their technique of choice without significant additional risk of adverse events.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"1711-1719"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12812511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145997968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HANDPub Date : 2026-11-01Epub Date: 2025-12-18DOI: 10.1177/15589447251387356
Léna G Dietrich, Sarah Messerli, Esther Vögelin, Rémy Liechti, Laura De Pellegrin, Dominique N Merky
{"title":"Arthroscopic Versus Open Surgery for Scaphoid Nonunion: A Retrospective Case-Control Study.","authors":"Léna G Dietrich, Sarah Messerli, Esther Vögelin, Rémy Liechti, Laura De Pellegrin, Dominique N Merky","doi":"10.1177/15589447251387356","DOIUrl":"10.1177/15589447251387356","url":null,"abstract":"<p><strong>Background: </strong>Currently, there is no consensus on the optimal surgical technique for scaphoid nonunion (arthroscopic vs open surgery). Open bone grafting is likely to result in better carpal alignment than arthroscopic bone grafting, but the clinical relevance of this issue is unclear. The aim of this retrospective study is to compare the clinical and radiological outcomes of arthroscopic versus open surgery for scaphoid nonunion.</p><p><strong>Methods: </strong>A retrospective case-control study was conducted, assessing patients who underwent surgery for scaphoid nonunion between October 2015 and March 2023. Inclusion criteria were age over 18 years and no preexisting degenerative disease or severe concomitant injuries that would prevent standardized follow-up treatment. We compared range of motion, grip strength, complication rates, and reoperation rates. Based on radiological data, consolidation, incidence of posttraumatic osteoarthritis of the wrist, and changes in the length of the scaphoid axis and position in the carpus were assessed.</p><p><strong>Results: </strong>After exclusion and matching, 42 of a total of 55 patients were included for comparative data analysis (22 in the arthroscopic and 20 in the open treatment group). Baseline patient characteristics were comparable in both groups. The mean operating time averaged 157 minutes (SD 19.74) for open surgery versus 151 minutes (SD 42.95) for arthroscopic approaches. There were no statistically significant differences between the two groups regarding wrist range of motion and grip strength at 3- and 12-month follow-up. The incidence of posttraumatic wrist osteoarthritis, complication and reoperation rates were comparable. Regarding consolidation, there was a statistically significant higher radiological consolidation rate after 3 months in the arthroscopic group compared to the open approach. Consolidation rates leveled out at the 12-month follow-up.</p><p><strong>Discussion: </strong>The arthroscopic procedure demonstrates a valid alternative to the open method with comparable postoperative subjective outcomes (especially pain) and similarly satisfactory range of motion as well as strength measurements. Surgical time can be reduced using the arthroscopic approach, albeit an initial steep learning curve must be considered. Arthroscopic reconstructions are usually less painful and may be performed as an outpatient basis.</p><p><strong>Conclusion: </strong>This study supports the use of arthroscopic reconstruction of scaphoid pseudarthrosis as it marks a time-efficient alternative to the current gold standard open approach without loss of function and faster time to consolidation.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"1676-1685"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12716968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145781176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HANDPub Date : 2026-11-01Epub Date: 2026-01-20DOI: 10.1177/15589447251411544
Selcen S Yuksel, Carly Schanock, David D Rivedal
{"title":"Treatment of Dupuytren's Disease of the Proximal Interphalangeal Joint: A Systematic Review and Network Meta-analysis.","authors":"Selcen S Yuksel, Carly Schanock, David D Rivedal","doi":"10.1177/15589447251411544","DOIUrl":"10.1177/15589447251411544","url":null,"abstract":"<p><strong>Background: </strong>Postoperative outcomes for Dupuytren's disease (DD) of the proximal interphalangeal joint (PIPJ) are highly variable, and the condition often proves refractory to correction. The aim of this study was to summarize the best available evidence on the treatments for DD of the PIPJ.</p><p><strong>Methods: </strong>A systematic review and network meta-analysis were conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Medline, Cumulated Index in Nursing and Allied Health Literature (CINAHL), Scopus, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science were searched for randomized controlled trials (RCTs) comparing treatments for DD of the PIPJ in adults.</p><p><strong>Results: </strong>A total of 19 RCTs were included in this study. Based on network meta-analysis of operative techniques, limited fasciectomy resulted in significantly lower total passive extension deficit compared with collagenase injections and percutaneous needle fasciotomy in the short (1-12 weeks) and long term (>2 years). Limited fasciectomy also had the lowest rates of recurrence in the long term when compared with percutaneous needle fasciotomy and collagenase injection. Collagenase injections led to significant clinical improvement compared with placebo. Triamcinolone injections in conjunction with needle fasciotomy were more effective in correcting contracture than needle fasciotomy alone. Postoperative splinting, timing of manual manipulation after collagenase injections, use of dermofasciectomy, and incision type for limited fasciectomy had no impact on correction or recurrence of DD of the PIPJ.</p><p><strong>Conclusions: </strong>While DD of the PIPJ is often refractory, limited fasciectomy provides better and more long-lasting contracture correction compared with collagenase injections or needle fasciotomy. More RCTs are needed to effectively compare treatment techniques for this condition.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"1728-1736"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12819120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146010104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HANDPub Date : 2026-11-01Epub Date: 2026-01-25DOI: 10.1177/15589447251411545
Rachel Hyzny, Stacia Ruse, Michael Niemann, Christopher Gonzalez, Jenna Dvorsky, John Fowler
{"title":"Enhancing Carpal Tunnel Syndrome Diagnosis: The Combined Use of CTS-6 and Ultrasound Measured Median Nerve CSA.","authors":"Rachel Hyzny, Stacia Ruse, Michael Niemann, Christopher Gonzalez, Jenna Dvorsky, John Fowler","doi":"10.1177/15589447251411545","DOIUrl":"10.1177/15589447251411545","url":null,"abstract":"<p><strong>Background: </strong>While clinical examination for carpal tunnel syndrome (CTS) is the first-line diagnostic method, its accuracy can vary, particularly among clinicians without specialized training. The CTS-6 questionnaire and ultrasound measurement of the median nerve's cross-sectional area (CSA) are two widely studied diagnostic methods. Combining these tools may provide a more reliable and standardized approach to CTS diagnosis.</p><p><strong>Methods: </strong>A review was conducted of patients aged 18 years or older screened for CTS from June 2023 to Sept 2023. We combined scores using the formula (CTS-6 score + 2 × CSA) based on a previous study by Kimura et al. We then used the Index of Union and positive likelihood ratio (PLR) to analyze the optimal cutoff values for the combined score.</p><p><strong>Results: </strong>A total of 142 hands were analyzed. The combined score had the highest sensitivity, while the CTS-6 alone had the highest specificity. The accuracy of the combined score with a cutoff value of 31.25 was equal to that of the CTS-6 score alone. Per the Index of Union, the optimized cutoff for the combined score was 27.68. Maximizing the PLR, the combined score cutoff was found to be 34.08.</p><p><strong>Conclusions: </strong>Combining the CTS-6 and median nerve CSA offers the most accurate method for diagnosing CTS. A lower cutoff value (27.68 vs. 31.25) improved the sensitivity of the combined score, demonstrating a strong diagnostic performance for CTS as a screening tool. Alternatively, using the PLR-optimized cutoff (34.08), this becomes a highly specific confirmatory test.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"1621-1626"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12834684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HANDPub Date : 2026-11-01Epub Date: 2025-11-30DOI: 10.1177/15589447251391375
Chul Ki Goorens, Niels Debaenst, Kjell Van Royen, Bert Vanmierlo
{"title":"Mid-term Outcome of the All-Dorsal Augmented Scapholunate Ligament Reconstruction for Chronic Scapholunate Instability.","authors":"Chul Ki Goorens, Niels Debaenst, Kjell Van Royen, Bert Vanmierlo","doi":"10.1177/15589447251391375","DOIUrl":"10.1177/15589447251391375","url":null,"abstract":"<p><strong>Background: </strong>Chronic scapholunate instability can be treated with the all-dorsal scapholunate augmented reconstruction This study examined the mid-term outcome of a multicentre series of this technique.</p><p><strong>Methods: </strong>Patients with chronic symptomatic scapholunate instability that underwent surgical treatment were included. Patients with wrist arthritis were excluded. Assessment consisted of clinical (range of motion, grip strength, pain), functional (Disabilities of the Arm, Shoulder and Hand [DASH] score; Patient-Related Wrist Evaluation [PRWE] score and patient satisfaction), and radiographic measurements (scapholunate distance, scapholunate angle, radiolunate angle, capitolunate angle, dorsal scaphoid translation, and drill hole diameter).</p><p><strong>Results: </strong>Eighteen consecutive patients were included. The mean age was 44.4 years, and the mean follow-up was 4.2 years, with a minimum of 2 years. Five patients (27.8%) were unavailable for final follow-up due to revision surgery caused by recurrent symptomatic instability. Compared to the contralateral side, the mean postoperative flexion was 60.6%, extension 66.5%, and grip strength 62.0%. Postoperatively, the mean visual analogue scale pain score was 2.5, mean DASH score 17.9, and mean PRWE score 26.0. Postoperative radiographic parameters did not differ significantly from preoperative values. However, an increased dorsal scaphoid translation and scapholunate and capitolunate angle were observed in the cohort requiring revision. Postoperatively, 59% of drill holes significantly increased in size during follow-up. Radiographic bone collapse of the scaphoid or lunate was observed in 3 patients (16.8%).</p><p><strong>Conclusions: </strong>Our mid-term study showed a high overall failure rate of 44.4% for the all-dorsal scapholunate augmented reconstruction. Failure occurred more in patients with higher degrees of scapholunate instability. The remaining patients had good clinical and functional outcomes.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"1635-1643"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12668980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145648366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HANDPub Date : 2026-11-01Epub Date: 2025-12-12DOI: 10.1177/15589447251395089
Kevin Y Chen, Seth Ahlquist, Christopher Gajewski, Scott Nelson, Nicholas M Bernthal, Lauren E Wessel
{"title":"Distal Upper Extremity Sarcoma Epidemiology: A Single-Institution Review.","authors":"Kevin Y Chen, Seth Ahlquist, Christopher Gajewski, Scott Nelson, Nicholas M Bernthal, Lauren E Wessel","doi":"10.1177/15589447251395089","DOIUrl":"10.1177/15589447251395089","url":null,"abstract":"<p><strong>Background: </strong>Sarcoma management guidelines in the extremities have been developed based on grouped averages, which are weighted toward lower extremity sarcomas. However, sarcomas in the forearm, wrist, hand, and fingers present unique management challenges given proximity to neurovascular structures and smaller presenting size. This study aims to describe the presenting characteristics of upper extremity sarcomas evaluated at our tertiary referral hospital from 2015 to 2022.</p><p><strong>Methods: </strong>Pathology reports from 7888 upper extremity specimens were retrospectively reviewed, yielding 119 sarcoma entries belonging to 72 patients. Operative and clinic notes, pathology reports, and radiographic images were reviewed. Baseline demographic variables (age, sex, race) and tumor-specific characteristics were collected for all 72 patients. Survival characteristics (tumor recurrence, presence of metastasis) were collected for patients with a minimum of 6 months of follow-up.</p><p><strong>Results: </strong>The most common upper extremity sarcomas were undifferentiated pleomorphic sarcoma (21/72, 29%) and myxofibrosarcoma (17/72, 24%). Sixteen of 44 patients (36%) developed metastasis, and 14 of 44 patients (32%) developed local recurrence. Eight of 16 patients who developed metastases presented with tumor sizes less than 5 cm, and 9 of 14 patients who developed recurrence presented with tumor sizes less than 5 cm. Size of tumor at presentation was neither statistically associated with metastasis (<i>P</i> = .82) nor with recurrence (<i>P</i> = .28).</p><p><strong>Conclusions: </strong>Upper extremity sarcomas are a heterogeneous group of highly aggressive tumors. Current biopsy guidelines in sarcoma surveillance may not capture a majority of sarcomas in the upper extremity given the high frequency of small dimensions and indolent symptoms in even high-grade lesions.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"1742-1747"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12700772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145742537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}