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A review of research process, data collection and analysis 回顾研究过程、数据收集和分析
Insights in Biology and Medicine Pub Date : 2019-01-11 DOI: 10.29328/JOURNAL.IBM.1001014
S. Niraula
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引用次数: 7
Similarity between Some Biological Systems, Organotropism and Metastatic Process: Active Role Played By Secondary Organ? 某些生物系统的相似性、器官亲和性和转移过程:次生器官的积极作用?
Insights in Biology and Medicine Pub Date : 2018-06-19 DOI: 10.29328/JOURNAL.IBM.1001012
M. Luisetto, Behzad Nili-Ahmadabadi, Hossein Nili-Ahmadabadi, G. Mashori, Gamal Abdul Hamid, K. Khan, B. Nili-Ahmadabadi, Ahmed Yesvi Rafa, L. Cabianca
{"title":"Similarity between Some Biological Systems, Organotropism and Metastatic Process: Active Role Played By Secondary Organ?","authors":"M. Luisetto, Behzad Nili-Ahmadabadi, Hossein Nili-Ahmadabadi, G. Mashori, Gamal Abdul Hamid, K. Khan, B. Nili-Ahmadabadi, Ahmed Yesvi Rafa, L. Cabianca","doi":"10.29328/JOURNAL.IBM.1001012","DOIUrl":"https://doi.org/10.29328/JOURNAL.IBM.1001012","url":null,"abstract":"","PeriodicalId":128593,"journal":{"name":"Insights in Biology and Medicine","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115022308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Transcriptome-wide association study: Opportunity and challenges for cancer studies 全转录组关联研究:癌症研究的机遇与挑战
Insights in Biology and Medicine Pub Date : 1900-01-01 DOI: 10.29328/journal.ibm.1001023
Shang Kendy, He Jingni
{"title":"Transcriptome-wide association study: Opportunity and challenges for cancer studies","authors":"Shang Kendy, He Jingni","doi":"10.29328/journal.ibm.1001023","DOIUrl":"https://doi.org/10.29328/journal.ibm.1001023","url":null,"abstract":"Genome-wide association studies (GWAS) have uncovered thousands of single nucleotide polymorphism (SNP) loci that are associated with complex traits. However, the majority of GWAS discoveries are located in non-coding regions and the biological mechanisms behind these associations are not well understood. Transcriptome-wide association studies (TWAS) have gained popularity in recent years by generating biological interpretable discoveries and facilitating the identification of novel associations that have been missed by GWAS. TWAS has identified more than hundreds of susceptibility genes for many complex diseases and traits, including cancers. Here, in this review, we first summarize TWAS methods, then discuss the opportunities for cancer studies and finally review current challenges and future directions for this method.","PeriodicalId":128593,"journal":{"name":"Insights in Biology and Medicine","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114848733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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