Hemodialysis International最新文献

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Treatment of a patient with inoperable tumoral calcinosis associated with end stage kidney disease: A case report 治疗一名无法手术的肿瘤性钙化伴终末期肾病患者:病例报告。
IF 1.2 4区 医学
Hemodialysis International Pub Date : 2024-10-17 DOI: 10.1111/hdi.13179
Sarah K. Couser, Donna J. Claes, Sydney Huesman, David K. Hooper
{"title":"Treatment of a patient with inoperable tumoral calcinosis associated with end stage kidney disease: A case report","authors":"Sarah K. Couser,&nbsp;Donna J. Claes,&nbsp;Sydney Huesman,&nbsp;David K. Hooper","doi":"10.1111/hdi.13179","DOIUrl":"10.1111/hdi.13179","url":null,"abstract":"<p>We describe a case of severe symptomatic tumoral calcinosis in a young man with end stage kidney disease secondary to antineutrophil cytoplasmic antibodies-associated vasculitis with longstanding hyperphosphatemia and secondary hyperparathyroidism while on several years of peritoneal dialysis. The use of intravenous sodium thiosulfate, optimization of clearance with five times weekly hemodialysis, and intradialytic nutrition were used to treat his inoperable tumoral calcinosis. Over 3 months, he had a remarkable reduction in the size of his calcified masses and associated improvement in pain. He subsequently received a living donor kidney transplant.</p>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"29 1","pages":"116-120"},"PeriodicalIF":1.2,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plaque psoriasis with renal dysfunction successfully treated with ixekizumab 使用ixekizumab成功治疗伴有肾功能障碍的斑块状银屑病。
IF 1.2 4区 医学
Hemodialysis International Pub Date : 2024-10-13 DOI: 10.1111/hdi.13185
Xinyu Zhu, Xiaoyuan Pan, Zhengbang Dong
{"title":"Plaque psoriasis with renal dysfunction successfully treated with ixekizumab","authors":"Xinyu Zhu,&nbsp;Xiaoyuan Pan,&nbsp;Zhengbang Dong","doi":"10.1111/hdi.13185","DOIUrl":"10.1111/hdi.13185","url":null,"abstract":"<p>Psoriasis is an immune-mediated chronic inflammatory skin disease and chronic kidney disease is one of the common comorbidities of psoriasis. Ixekizumab, a humanized IgG4 monoclonal antibody, has been approved for the treatment of moderate-to-severe plaque psoriasis in recent years. However, ixekizumab has not been studied in a population of patients with renal insufficiency. We report two cases of plaque psoriasis patients with renal dysfunction successfully treated with ixekizumab without dose reduction,which experience no side effects and does not cause further kidney injury.</p>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"29 1","pages":"126-129"},"PeriodicalIF":1.2,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing the effectiveness of a blended video plus face-to-face educational program with a face-to-face educational program on quality of life among adolescents undergoing hemodialysis in Palestine 比较混合视频加面对面教育计划与面对面教育计划对巴勒斯坦接受血液透析的青少年生活质量的影响。
IF 1.2 4区 医学
Hemodialysis International Pub Date : 2024-10-13 DOI: 10.1111/hdi.13182
Nawras Fashafsheh, Ping Lei Chui, Mahmoud Danaee, Ahmad Ayed, Lee Lee Lai
{"title":"Comparing the effectiveness of a blended video plus face-to-face educational program with a face-to-face educational program on quality of life among adolescents undergoing hemodialysis in Palestine","authors":"Nawras Fashafsheh,&nbsp;Ping Lei Chui,&nbsp;Mahmoud Danaee,&nbsp;Ahmad Ayed,&nbsp;Lee Lee Lai","doi":"10.1111/hdi.13182","DOIUrl":"10.1111/hdi.13182","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Hemodialysis is frequently used as a primary treatment for individuals with end-stage kidney disease (ESKD), and it significantly impacts the quality of life in adolescents undergoing this procedure. Providing a hemodialysis education to these patients is a valuable strategy for enhancing their well-being. The aim of the study is to assess the effect of the video-assisted educational program on the quality of life among adolescents undergoing hemodialysis in Palestine.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study employed a quasi-experimental design, a pre-test–post-test interventional study, involving a sample of 68 adolescent patients between the ages of 13 and 18 diagnosed with ESKD. The quality of life level was assessed in both groups using an Arabic version of the Pediatric Quality of Life Inventory™ version 3.0 ESKD Module survey. The study was conducted at the dialysis units in four hospitals associated with Augusta Victoria Hospital, An-Najah University Hospital, Palestine Medical Complex/Ramallah, and Beit Jala (Al Housain) Hospital. The study involved providing tailored face-to-face educational sessions with video assistance to the experimental group, while the control group received regular face-to-face education.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Findings</h3>\u0000 \u0000 <p>The Generalized Estimating Equation analysis revealed no significant differences in quality of life between the experimental and control groups over time, across pre-test, post-test, and follow-up periods (<i>p</i> ≥ 0.05). However, within the experimental group, there was a significant improvement in total quality of life scores between the pre-test, post-test, and post-test follow-up (<i>p</i> ≤ 0.001), although the difference between the pre-test and follow-up approached significance but was not statistically significant (<i>p</i> = 0.056). In contrast, the control group showed significant differences in quality of life across the pre-test, post-test, and follow-up time points (<i>p</i> ≤ 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Implementing suitable interventions can potentially enhance the quality of life for individuals undergoing hemodialysis. Consequently, we suggest using video-based education as a cost-effective, uncomplicated, and engaging approach for educating hemodialysis patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"29 1","pages":"83-92"},"PeriodicalIF":1.2,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Features associated with arteriovenous fistula patency. A meta-analysis 与动静脉瘘通畅相关的特征。荟萃分析。
IF 1.2 4区 医学
Hemodialysis International Pub Date : 2024-10-13 DOI: 10.1111/hdi.13183
Dongjuan Zhang, Jing Liang, Yang Yang
{"title":"Features associated with arteriovenous fistula patency. A meta-analysis","authors":"Dongjuan Zhang,&nbsp;Jing Liang,&nbsp;Yang Yang","doi":"10.1111/hdi.13183","DOIUrl":"10.1111/hdi.13183","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>It is unclear if cannulation-associated variables such as timing of first cannulation, access creation method, cannulation technique, or needle type are associated with the outcomes of arteriovenous fistulas. We conducted a meta-analysis to investigate such potential associations with 1-year primary patency.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twenty-eight publications with titles that included “arteriovenous fistula,” “patency,” “cannulation,” “metric,” “first cannulation,” “hemodialysis,” “complication,” “vascular,” “nursing,” and “puncture” were retrieved and reviewed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Findings</h3>\u0000 \u0000 <p>The 1-year primary patency rates ranged from 0.32 to 0.93. Primary patency rates were significantly lower in patients in whom initial cannulation was done less than 1.5 months after fistula creation compared to fistulas first cannulated more than 1.5 months after anastomosis (odds ratio [OR] = 0.41, 95% confidence interval [CI]: 0.32–0.52). The effect of cannulation timing on primary patency rate was attenuated when plastic cannulas were used during the first two to three puncture weeks compared to metal needles (OR = 0.62 vs. 0.34; <i>p</i> = 0.032). Fistulas in the upper arm did not have a higher 1-year primary patency compared to those in the forearm (OR = 1.05, 95% CI: 0.93–1.19). Primary patency of upper arm arteriovenous fistulas was higher in reports from the Americas or Europe compared to reports from Asia. Buttonhole cannulation was not associated with higher patency rates at 1 year compared to rope-ladder cannulation (OR = 1.14, 95% CI: 0.75–1.71).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Early cannulation was associated with reduced 1-year arteriovenous fistula patency. This association was reduced when plastic cannulas were used during the initial 2–3 weeks.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"29 1","pages":"31-46"},"PeriodicalIF":1.2,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Involvement of healthcare staff in hospital hygiene during emergency hemodialysis 医护人员参与紧急血液透析期间的医院卫生。
IF 1.2 4区 医学
Hemodialysis International Pub Date : 2024-10-13 DOI: 10.1111/hdi.13186
Razzok El Mahdi, Machmachi Imane, Maleb Adil, Mekhfi Hassane, Bentata Yassamine
{"title":"Involvement of healthcare staff in hospital hygiene during emergency hemodialysis","authors":"Razzok El Mahdi,&nbsp;Machmachi Imane,&nbsp;Maleb Adil,&nbsp;Mekhfi Hassane,&nbsp;Bentata Yassamine","doi":"10.1111/hdi.13186","DOIUrl":"10.1111/hdi.13186","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Healthcare-associated infections are still a worrying health problem that complicates patient care and increases morbidity and mortality. The incidence of infections in hemodialysis patients is still high and they constitute the second cause of hospitalization and death in this category.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>The study's objective was to evaluate nursing and medical staff's involvement in hospital hygiene.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This is an observational study that took place within the hemodialysis unit of a Moroccan university hospital from March 2021 to June 2021. A surface swabbing technique for bacteriological examination was also carried out.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study revealed some shortcomings regarding hand hygiene which was respected by the nurses in only 17.5% of sessions and in 42.2% by the doctors. Other shortcomings in asepsis measures, were also noted such as the non-change of gloves after skin preparation (1.03%) and before manual compression. The serological status of patients concerning HBV, HVC, and HIV was also not always known (31.1%). The bacteriological samples from the surfaces also showed colonization of the medical devices and the ultrasound scanner used for the ultrasound-guided introduction of the central catheters. The results of the study showed some deviations concerning the recommendations; however, they are comparable to other studies conducted internationally, especially in terms of hand hygiene.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Our study results highlight some shortcomings adherence to hygiene measures like inconsistent disinfection of medical devices and dialysis stations, as well as insufficient hand hygiene practices among some staff members. However, we observed an improvement in practices following the implementation of awareness-raising sessions. To maintain improved hygiene practices and prevent infections, it is crucial to provide ongoing training for staff, ensure adequate resources, and regularly monitor compliance with hygiene standards.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"29 1","pages":"56-62"},"PeriodicalIF":1.2,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatal osmotic demyelination following urgent start hemodialysis in a patient with normal serum sodium 一名血清钠正常的患者在紧急开始血液透析后出现致命的渗透性脱髓鞘。
IF 1.2 4区 医学
Hemodialysis International Pub Date : 2024-10-09 DOI: 10.1111/hdi.13184
Subrahmanian Sathiavageesan
{"title":"Fatal osmotic demyelination following urgent start hemodialysis in a patient with normal serum sodium","authors":"Subrahmanian Sathiavageesan","doi":"10.1111/hdi.13184","DOIUrl":"10.1111/hdi.13184","url":null,"abstract":"<p>End stage kidney disease (ESKD) patients in the developing countries often present late for dialysis initiation with advanced uremia and life-threatening complications. Urgent start dialysis in such emergent situations exposes the patient to risk of uremia related complications as well as iatrogenic insults. We report the case of a middle-aged man with ESKD who presented late with acute pulmonary edema and hyperkalemia and developed osmotic demyelination syndrome following urgent start hemodialysis. Osmotic demyelination syndrome in this patient is noteworthy since there was no accompanying hyponatremia, the most commonly recognized antecedent. We propose that rapid lowering of serum osmolality by aggressive hemodialysis is sufficient to incite osmotic demyelination syndrome in patients who have long-standing uremia and high blood urea level. Malnutrition resulting from uremia might be a compounding factor in this scenario. Our patient had a characteristic initial presentation of osmotic demyelination syndrome with locked-in-state which later progressed to respiratory failure and death.</p>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"29 1","pages":"121-125"},"PeriodicalIF":1.2,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Renal satellite units in Pakistan: Challenges, efforts, and recommendations 巴基斯坦的肾脏卫星病房:挑战、努力和建议。
IF 1.2 4区 医学
Hemodialysis International Pub Date : 2024-10-01 DOI: 10.1111/hdi.13176
Abdullah Nadeem, Afsheen Khan, Ayesha Amir, Tasmiyah Siddiqui, Laiba Shakeel
{"title":"Renal satellite units in Pakistan: Challenges, efforts, and recommendations","authors":"Abdullah Nadeem,&nbsp;Afsheen Khan,&nbsp;Ayesha Amir,&nbsp;Tasmiyah Siddiqui,&nbsp;Laiba Shakeel","doi":"10.1111/hdi.13176","DOIUrl":"10.1111/hdi.13176","url":null,"abstract":"<p>This commentary delves into the complexities surrounding chronic kidney disease management in Pakistan, specifically examining the critical role played by renal satellite units in providing accessible dialysis services. Chronic kidney disease in Pakistan accounts for 3.9% of total deaths, warranting a focused exploration of challenges and potential solutions. RSUs, smaller entities affiliated with main renal units, emerge as key players in addressing issues of geographic accessibility and diminishing travel burdens for chronic kidney disease patients. Challenges such as financial constraints, limited resources, and staff shortages, particularly in rural settings, pose significant hurdles to the effective functioning of RSUs. This commentary emphasizes the importance of clear eligibility criteria, robust vascular access support, regular physician engagement, and the strategic integration of telemedicine. It explores diverse funding models, including government allocations, community contributions, and philanthropic partnerships, as potential solutions to alleviate cost-related concerns. The commentary advocates for a holistic, cost-effective approach to chronic kidney disease care, highlighting the transformative potential of renal satellite units in improving health outcomes across varied settings.</p>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"28 4","pages":"393-396"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous neck hematoma in a hemodialysis patient: A case report 一名血液透析患者的自发性颈部血肿:病例报告。
IF 1.2 4区 医学
Hemodialysis International Pub Date : 2024-10-01 DOI: 10.1111/hdi.13177
Yanhua You, Qi Sun
{"title":"Spontaneous neck hematoma in a hemodialysis patient: A case report","authors":"Yanhua You,&nbsp;Qi Sun","doi":"10.1111/hdi.13177","DOIUrl":"10.1111/hdi.13177","url":null,"abstract":"<p>We present a 60-year-old maintenance hemodialysis patient who initially presented with neck swelling, which was diagnosed as a thyroid issue. Following a hemodialysis session, the swelling in the neck progressively enlarged, leading to respiratory distress and eventual cardiac arrest. During a life-saving tracheotomy, dark red blood was observed, and endotracheal intubation was urgently performed. Subsequent computed tomography examination identified multiple areas of slight high-density images in the nasopharyngeal cavity, oropharyngeal cavity, and esophagus. As time passed, the patient's hematoma underwent spontaneous absorption, but signs of recovery were absent. We discuss the rarity, etiology, diagnosis, and management of spontaneous neck hematoma in maintenance hemodialysis patients.</p>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"28 4","pages":"444-447"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/hdi.13177","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bivalirudin as an anticoagulation strategy for acute hemodialysis in children: Two cases with a summary of recent literature 比伐卢定作为儿童急性血液透析的抗凝策略:两个病例及最新文献综述。
IF 1.2 4区 医学
Hemodialysis International Pub Date : 2024-10-01 DOI: 10.1111/hdi.13181
Tanguy Viaene, Evelyn Dhont, Floris Vanommeslaeghe, Sunny Eloot, Filip De Somer, Jonathan De Rudder, Veerle Mondelaers, Evelien Snauwaert
{"title":"Bivalirudin as an anticoagulation strategy for acute hemodialysis in children: Two cases with a summary of recent literature","authors":"Tanguy Viaene,&nbsp;Evelyn Dhont,&nbsp;Floris Vanommeslaeghe,&nbsp;Sunny Eloot,&nbsp;Filip De Somer,&nbsp;Jonathan De Rudder,&nbsp;Veerle Mondelaers,&nbsp;Evelien Snauwaert","doi":"10.1111/hdi.13181","DOIUrl":"10.1111/hdi.13181","url":null,"abstract":"<p>Unfractionated heparin is the most used anticoagulative agent for extracorporeal settings in children, including acute hemodialysis modalities. In certain situations, such as heparin-induced thrombocytopenia, alternatives must be applied. The direct thrombin inhibitor bivalirudin has come forth as an attractive substitute. Bivalirudin is currently only approved for adult use in specific percutaneous coronary intervention settings. However, it has a growing off-label popularity in different contexts for both adult and pediatric patients. Experience with bivalirudin in children is mainly limited to extracorporeal membrane oxygenation, ventricular assist devices and during cardiopulmonary bypass surgery. Literature about its use as anticoagulation strategy for pediatric hemodialysis is very scarce. Here, we present two pediatric cases where bivalirudin was used during acute hemodialysis, followed by a short summary of recent literature.</p>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"28 4","pages":"448-455"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of topical gabapentin cream in treating pruritus in dialysis patients: A randomized controlled trial 外用加巴喷丁乳膏治疗透析患者瘙痒症的效果:随机对照试验。
IF 1.2 4区 医学
Hemodialysis International Pub Date : 2024-08-20 DOI: 10.1111/hdi.13175
Gita Faghihi, Parisa Mohammadian, Bahareh Abtahi-Naeini, Mojtaba Akbari, Ali Mohammad Sabzghabaee, Mojgan Mortazavi
{"title":"Effectiveness of topical gabapentin cream in treating pruritus in dialysis patients: A randomized controlled trial","authors":"Gita Faghihi,&nbsp;Parisa Mohammadian,&nbsp;Bahareh Abtahi-Naeini,&nbsp;Mojtaba Akbari,&nbsp;Ali Mohammad Sabzghabaee,&nbsp;Mojgan Mortazavi","doi":"10.1111/hdi.13175","DOIUrl":"10.1111/hdi.13175","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Gabapentin is an antiepileptic drug that alleviates neuropathic pain. Its oral use reduces the intensity of pruritus in patients receiving chronic dialysis therapy. However, it could lead to toxicity because of the patients' renal deficiency. In this study, we assessed the use of gabapentin topical in treating pruritus in dialysis patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This randomized, triple-blinded trial was performed on 80 patients divided into two groups randomly (40 in each group). In intervention group, 92.5% of the patients were on hemodialysis. Patients in intervention and control groups were provided with 5% gabapentin and placebo topical creams every 2 weeks for a month. Both Visual Analog Scale and 12-item Pruritus Severity Score questionnaire were used to evaluate itching intensity and score before treatment, a month, and 2 months after starting treatment in both groups. In addition, the effect of itching on quality of life was investigated with the same questionnaire.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Findings</h3>\u0000 \u0000 <p>Eighty patients (40 in each group) participated in our study. No complication was found in our intervention group. Itching score significantly decreased after a month and 2 months of follow-up in intervention group (<i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Our results showed that 5% gabapentin topical cream can be effective in reducing itching in different areas of the body. None of our patients reported complications.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"28 4","pages":"429-434"},"PeriodicalIF":1.2,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142010108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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