{"title":"[Ocular lesions of interest to an internist].","authors":"M C Borgia, P Ciafrone, A R Federici","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12732,"journal":{"name":"Giornale di clinica medica","volume":"71 11","pages":"651-2, 655-66"},"PeriodicalIF":0.0,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13242057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The venous system in essential arterial hypertension].","authors":"R Gava, E Casiglia, G C Beltrami, L Grezzana","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12732,"journal":{"name":"Giornale di clinica medica","volume":"71 11","pages":"675-8"},"PeriodicalIF":0.0,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13241971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Not very safe anti-inflammatory therapy: NSAID and milk].","authors":"R Gava","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12732,"journal":{"name":"Giornale di clinica medica","volume":"71 11","pages":"679-85"},"PeriodicalIF":0.0,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13241972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B Fabris, F De Biasi, F Fischetti, R Leprini, M Castellano, R Carretta
{"title":"[Activity and number of lymphocyte beta adrenergic receptors after protracted treatment with mepindolol sulfate of patients with essential arterial hypertension].","authors":"B Fabris, F De Biasi, F Fischetti, R Leprini, M Castellano, R Carretta","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>beta-Blockers are widely used in the treatment of high blood pressure. To study clinical and pharmacological role of beta-adrenoceptor antagonist with intrinsic sympathomimetic activity (ISA), lymphocyte beta 2-adrenoceptor density, assessed by 3H-dihydroalprenolol binding, was investigated in 10 hypertensive patients (8 male, 2 female) aged 20-62 years before and after treatment with mepindolol (5 mg o.i.d.). After 3 months of therapy, both systolic (from 169.7 +/- 28.3 mmHg to 146.5 +/- 17.6 mmHg) and diastolic (from 108.7 +/- 17.5 mmHg to 93.6 +/- 8.7 mmHg) blood pressure decreased significantly. Similarly heart rate decreased after treatment (from 76.5 +/- 10.1 b/min to 62.7 +/- 3.4 b/min). Mepindolol treatment decreased beta 2-adrenoceptor density from 1112.2 +/- 459.6 sites/cell to 295.1 +/- 131.2 sites/cell. Plasma noradrenaline values did not correlate with lymphocyte beta 2-receptor number both before and after treatment. Our results show that ISA may play an important role in modulating beta 2-adrenoceptor density on lymphocyte surface. This biological effect could be relevant in reducing the so called \"propranolol rebound effect\".</p>","PeriodicalId":12732,"journal":{"name":"Giornale di clinica medica","volume":"71 11","pages":"639-44"},"PeriodicalIF":0.0,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13123195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Urinary schistosomiasis: description of a case. Clinico-therapeutic considerations and preventive measures].","authors":"C Di Bari, E Sforza","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In Italy, imported cases of urinary schistosomiasis may be frequently undiagnosed, because the symptoms are mild and the number of schistosome eggs in urine is low. The Authors report one case of S. haematobium infection in whom the diagnosis was suspected on the basis of the anamnestic and clinical data and confirmed by the presence of typical eggs in urine and histologically in biopsies taken at cystoscopy. Moreover preventive measures are suggested for the individuals who go to those Countries where schistosomiasis is endemic.</p>","PeriodicalId":12732,"journal":{"name":"Giornale di clinica medica","volume":"71 11","pages":"645-7"},"PeriodicalIF":0.0,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13282974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Effects of physical activity on microalbuminuria in type 1 diabetics without nephropathy].","authors":"C Taboga, L Tonutti, C Noacco","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Physical exercise is a well known provocative test for early renal abnormalities detection in diabetes mellitus. Aim of our study was to evaluate the effect of daily activity and physical exercise on albumin excretion rate (AER) in 2 groups of albustix negative type I diabetics (IDDM). In group I of 76 patients aged 7-58 years, AER measured in 24 h urine (14.1 +/- 1.7 micrograms/min) and overnight urine (11.1 +/- 1.7 micrograms/min) was similar. A significant correlation was found between AER values obtained from the two urine collection procedures (r = 0.55; p less than 0.001). In group 2 of 37 patients aged 7-48 years and in 25 matched controls, the effect of physical exercise on AER was evaluated comparing overnight urine and post-exercise urine collection. AER increased significantly in IDDM after exercise. In conclusion our results show that 1) AER is not affected by daily activity; 2) physical exercise is a usefull provocative test to detect early renal abnormalities.</p>","PeriodicalId":12732,"journal":{"name":"Giornale di clinica medica","volume":"71 10","pages":"569-72"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13439913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}