G B Migliori, A Borchesi, E Comaschi, C V Landoni, M Grandi, A Satta, A Spanevello, G Vocaturo, M Neri
{"title":"Preliminary study to antituberculosis chemotherapy in a region of sub-Saharian Africa: annual risk of tuberculosis infection calculation and tuberculin survey.","authors":"G B Migliori, A Borchesi, E Comaschi, C V Landoni, M Grandi, A Satta, A Spanevello, G Vocaturo, M Neri","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A tuberculin survey was performed in Arua District (577,799 inhabitants, recent return of refugees from Zaire and Sudan) in 1987 prior to the implementation of antituberculosis Chemotherapy and Control Programme. 50 clusters (schools) of 30 pupils each were selected in the 7 Counties by Sistematic Random Sampling. 1110 students 10 year old without BCG vaccination scar were injected with 5 IU of PPD; 1016 of them (more than 6% of the estimated district population of 10 year of age) came back after 72 hours for reading. 125 of them were positives (more than 10 mm of induration). The Infection Rate detected was 1.23% +/- 0.19. Considering the infection rates found by the Ugandan National Surveys done in 1950 (2.6%) and in 1970 (2.3%), and the slight slope of the curve calculated on those values we have underestimated the real Infection Rate in the district. To avoid this bias we suggest to include schools in sampling (it is simple and cost-effective) only if the Student's population is likely to be representative of the general population.</p>","PeriodicalId":12704,"journal":{"name":"Giornale italiano di chemioterapia","volume":"39 1-3","pages":"5-9"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12537939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Losasso, A Loffreda, M Angrisani, I Marabese, C Vacca, F Rossi
{"title":"[Pharmacologic interactions between quinolones and oral hypoglycemic agents. An experimental study on rabbits].","authors":"C Losasso, A Loffreda, M Angrisani, I Marabese, C Vacca, F Rossi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The association between antibiotics and oral hypoglycemic agents can determine various pharmacological interactions. The aim of our work has been to verify experimentally the eventual pharmacological interactions that may occur when some quinolones (nalidixic acid, ofloxacin, pefloxacin and sparfloxacin) are administered in association with oral hypoglycemic drugs (phenphormine and glibenclamide). Our results showed that ofloxacin, pefloxacin and sparfloxacin only at high dosages (not used in the human clinic) can increase the phenphormine and glibenclamide hypoglycemic effect. The nalidixic acid, just at therapeutic doses, is able to increase the hypoglycemic effect of the drugs studied.</p>","PeriodicalId":12704,"journal":{"name":"Giornale italiano di chemioterapia","volume":"39 1-3","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12538880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Activity of two benzofuran-imidazoles, IM/B/4-62 and IM/B/4-66, against experimental infections with Candida albicans and Trichophyton mentagrophytes.","authors":"F Dubini, M G Bellotti, L Riviera","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The therapeutic activity of two new benzofuran-imidazoles, IM/B/4-62 and IM/B/4-66, formulated as 1% cream, has been evaluated against Candida albicans and Trichophyton mentagrophytes by inducing experimental vaginal candidosis in female rats and dermatophytosis in female guinea pigs. Results of the treatment were compared with those obtained by the same therapeutic regimen carried out with bifonazole. IM/B/4-66 proved to possess superior antimycotic activity to that of IM/B/4-62 and similar to that of bifonazole in both infections. Nmaley vaginal candidosis was cured in all the treated in animals at 6 days post-inoculation and skin lesions were healed in 9 of 10 animals at 15 days after infection, with negative cultures from all the infected sites.</p>","PeriodicalId":12704,"journal":{"name":"Giornale italiano di chemioterapia","volume":"39 1-3","pages":"17-21"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12538881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G Chisari, A M Lo Bue, L Drago, R Abbiati, M R Gismondo
{"title":"[Adhesion capacity of Enterococcus faecium (SF 68) and Enterococcus faecalis to various substrates].","authors":"G Chisari, A M Lo Bue, L Drago, R Abbiati, M R Gismondo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The author's studied the adherence ability of Enterococcus faecium SF 68 compared to that of Enterococcus faecalis IM 11f, on various substrates: vascular catheters and cardiac valves of rabbit, immunodepressed rats and diabetic rats. The bacterial adherence test was calculated by the number of bacteria adhered for microscopic field enlarged to 2000. The data obtained by scanning electron microscope SEM (Cambridge Stereoscan 150 MK2) revealed a different adherence action of the two germs on the various substrates. All the adherence tests showed a higher and uniform adherence activity of E. faecalis compared to that of E. faecium.</p>","PeriodicalId":12704,"journal":{"name":"Giornale italiano di chemioterapia","volume":"39 1-3","pages":"11-5"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12538884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Romano, L Minicucci, E Spallone, D Girosi, A Campelli, A Fabbri, C Palmero
{"title":"[Role of home therapy with ofloxacin in patients with cystic fibrosis (CF)].","authors":"L Romano, L Minicucci, E Spallone, D Girosi, A Campelli, A Fabbri, C Palmero","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12704,"journal":{"name":"Giornale italiano di chemioterapia","volume":"38 1-3","pages":"181-3"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12537905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G Majori, G Sabatinelli, F P Gianzi, C Cavallini, S Squarcione, A Forte
{"title":"[Treatment of imported malaria in Italy from 1989 and 1990].","authors":"G Majori, G Sabatinelli, F P Gianzi, C Cavallini, S Squarcione, A Forte","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12704,"journal":{"name":"Giornale italiano di chemioterapia","volume":"38 1-3","pages":"189-90"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12537908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Della Vittoria Scarpati, F De Vita, A Rippa, A Gattoni, N Pilerci, G Catalano
{"title":"[Response to an alternated chemo-radiotherapeutic treatment as neoadjuvant therapy of non-small-cell lung carcinoma (NSCLC). Report of a clinical case].","authors":"M Della Vittoria Scarpati, F De Vita, A Rippa, A Gattoni, N Pilerci, G Catalano","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12704,"journal":{"name":"Giornale italiano di chemioterapia","volume":"38 1-3","pages":"209-10"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12537920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Antibacterial agents and neurotransmission].","authors":"G B De Sarro, G Nisticò","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12704,"journal":{"name":"Giornale italiano di chemioterapia","volume":"38 1-3","pages":"27-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12537928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[From cervico-vaginitis to PID: therapeutic prospects].","authors":"G Tempera, A Cianci, G Nicoletti","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12704,"journal":{"name":"Giornale italiano di chemioterapia","volume":"38 1-3","pages":"55-6"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12537929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Chemoprophylaxis and chemotherapy of malaria in the 90s].","authors":"R Esposito","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12704,"journal":{"name":"Giornale italiano di chemioterapia","volume":"38 1-3","pages":"75-7"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12538637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}