Global & Regional Health Technology Assessment最新文献

{"title":"L’evoluzione del dialogo e dei rapporti tra AIFA, clinici, Società scientifiche e associazioni dei pazienti/organizzazioni di attivismo civico.","authors":"Alessandra Bianchi, Federica Piccolo, Elisabetta Iannelli, Maria Cristina Carena, Giuliano Buzzetti, Giovanna Scroccaro, Carmine Pinto","doi":"10.33393/grhta.2026.3643","DOIUrl":"https://doi.org/10.33393/grhta.2026.3643","url":null,"abstract":"","PeriodicalId":12627,"journal":{"name":"Global & Regional Health Technology Assessment","volume":"13 ","pages":"33-37"},"PeriodicalIF":0.5,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12888977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146165115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La cooperazione tra gli <i>stakeholder</i> per la sostenibilità del nuovo paradigma farmaceutico in Italia.","authors":"Valentina Drago, Eugenio Di Brino, Roberta Laurita, Filippo Rumi, Michele Basile, Andrea Pierini, Anna Ponzianelli, Francesca Patarnello, Paola Ianna, Filippo Drago","doi":"10.33393/grhta.2026.3675","DOIUrl":"10.33393/grhta.2026.3675","url":null,"abstract":"","PeriodicalId":12627,"journal":{"name":"Global & Regional Health Technology Assessment","volume":"13 ","pages":"24-32"},"PeriodicalIF":0.5,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12885122/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146156829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum in: Economic evaluation of distribution modalities for ostomy and incontinence medical devices within the Italian healthcare context.","authors":"Agostino Fortunato, Michele Basile, Debora Antonini, Eugenio Di Brino, Vincenzo Falabella, Pier Raffaele Spena, Filippo Rumi","doi":"10.33393/grhta.2026.3730","DOIUrl":"10.33393/grhta.2026.3730","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.33393/grhta.2026.3606.].</p>","PeriodicalId":12627,"journal":{"name":"Global & Regional Health Technology Assessment","volume":"13 ","pages":"23"},"PeriodicalIF":0.5,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12871047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146124621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum in: Exploring the administrative burden faced by hematologists: a comprehensive study in Italy.","authors":"Davide Petruzzelli, Marco Vignetti, Stefania Trasarti, Paolo Sportoletti, Silvia Della Torre, Roberto Cairoli, Francesca Pia Chiara Leone, Giuseppe Pompilio, Marco Gullì, Eva Brown Hajdukova, Davide Integlia","doi":"10.33393/grhta.2026.3725","DOIUrl":"10.33393/grhta.2026.3725","url":null,"abstract":"","PeriodicalId":12627,"journal":{"name":"Global & Regional Health Technology Assessment","volume":"13 ","pages":"22"},"PeriodicalIF":0.5,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12865382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146118650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in organizational impact, performance and quality related to the use of single- and/or reusable bronchoscopes in anesthesiology and resuscitation.","authors":"Pierfrancesco Tozzi, Katia Bruno, Giacomo Polito, Andrea Del Bianco, Beatrice Frasacco, Francesco Pugliese","doi":"10.33393/grhta.2026.3646","DOIUrl":"10.33393/grhta.2026.3646","url":null,"abstract":"<p><strong>Introduction: </strong>The use of fibrobronchoscopy increased significantly for collecting airway microbiological samples and during percutaneous tracheostomies and difficult intubations. Reusable bronchoscopes pose risks of contamination and damage due to their fragile structure and difficulties of cleaning and sterilization; single-use bronchoscopes have been introduced, offering reliability in terms of vision, maneuverability, suctioning capacity, and sterility, reducing the risk of hospital-acquired infections and improving logistical management.</p><p><strong>Methods: </strong>The study analyzed healthcare workers' and management's perceptions of single-use bronchoscopes versus reusable ones. Among the main objectives were to evaluate the organizational impact, quality, and performance of bronchoscopes, while also analyzing opinions on device features, safety in infection prevention, and ease of use during training.</p><p><strong>Results: </strong>In this analysis 66% of clinicians rated optimal image quality, and 90% of respondents highly appreciated the \"plug & play\" feature of disposable endoscopes; also, 45% of clinicians noted no significant differences in aspiration performance. Healthcare professionals felt more exposed to infectious agents with reusable endoscopes, believing disposable endoscopes required less vigilance and monitoring. In training, 80% of doctors and 100% of nurses considered disposable endoscopes more suitable due to their greater ease of use. Finally, the Overall Satisfaction of all healthcare workers was 75%.</p><p><strong>Conclusion: </strong>The analysis of results demonstrated that the use of single-use bronchoscopes in anesthesia and resuscitation is highly comparable in terms of clinical effectiveness to reusable ones and that significant advantages in costs and organizational impact were highlighted, positively impacting the daily workflow of healthcare workers.</p>","PeriodicalId":12627,"journal":{"name":"Global & Regional Health Technology Assessment","volume":"13 ","pages":"15-21"},"PeriodicalIF":0.5,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12809413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145997932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valutazione economica delle modalità distributive dei dispositivi medici per stomia e incontinenza nel contesto sanitario italiano.","authors":"Agostino Fortunato, Michele Basile, Debora Antonini, Eugenio Di Brin, Vincenzo Falabella, Pier Vincenzo Spena, Filippo Rumi","doi":"10.33393/grhta.2026.3606","DOIUrl":"10.33393/grhta.2026.3606","url":null,"abstract":"","PeriodicalId":12627,"journal":{"name":"Global & Regional Health Technology Assessment","volume":"13 ","pages":"7-14"},"PeriodicalIF":0.5,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12794625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health technology assessment of an automated unit-dose drug distribution system in a high-specialization national referral hospital of the Italian National Health Service.","authors":"Davide Croce, Francesco De Nardo, Francesca Convenga, Debjani Mueller, Michela Franzin","doi":"10.33393/grhta.2026.3615","DOIUrl":"10.33393/grhta.2026.3615","url":null,"abstract":"<p><strong>Introduction: </strong>Automated unit-dose (UD) medication distribution systems are increasingly recognized as enabling technologies for safer, more efficient, and traceable drug administration in hospitals. Closed-loop UD systems integrate electronic prescribing, automated dispensing, and bedside barcode scanning to ensure full traceability throughout the medication process. This study evaluated the clinical effectiveness, organizational impact, and cost-effectiveness of a closed-loop UD system implemented at a 930-bed national referral hospital in Northern Italy, compared with the previous ward-stock system.</p><p><strong>Methods: </strong>A convergent mixed-methods mini-Health Technology Assessment combined administrative, clinical, and financial data (2018-2021) with literature evidence and 18 semi-structured staff interviews. Outcomes included medication administration errors (MAEs), adverse drug reactions (ADRs), and preventable hospitalizations. Cost-effectiveness was assessed from the Italian National Health Service perspective, and qualitative findings were analyzed using framework analysis.</p><p><strong>Results: </strong>Based on literature-derived parameters, the model suggests a reduction in MAE rate from 10.6% to 5.0%, preventing an estimated 57,247 errors, 4,294 ADRs, and 42 hospitalizations per year. These outcomes were associated with net annual savings of €1.32 million and an ICER of €48.67 per error avoided. The model also indicated that around 34,000 nursing hours could be reallocated to direct patient care, while qualitative evidence highlighted improved staff satisfaction and medication traceability. Sensitivity analyses confirmed economic robustness in 95% of simulations.</p><p><strong>Conclusions: </strong>Implementation of a closed-loop UD system enhances medication safety, workflow efficiency, and cost-effectiveness, supporting its scalability as a strategic innovation aligned with institutional goals for quality and sustainability.</p>","PeriodicalId":12627,"journal":{"name":"Global & Regional Health Technology Assessment","volume":"13 ","pages":"1-6"},"PeriodicalIF":0.5,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12776020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145932797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Programmare e ripartire alle Aziende Sanitarie le risorse per la farmaceutica: una proposta dal Forum Politiche Farmaceutiche Regionali.","authors":"Claudio Jommi, Barbara Rebesco, Francesco Perrone, Rosy Amodeo, Alberto Bortolami","doi":"10.33393/grhta.2025.3598","DOIUrl":"10.33393/grhta.2025.3598","url":null,"abstract":"","PeriodicalId":12627,"journal":{"name":"Global & Regional Health Technology Assessment","volume":"12 ","pages":"265-270"},"PeriodicalIF":0.5,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12818173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146018299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evoluzione terapeutica: tradurre l’innovazione farmacologica in benefici tangibili per le persone con emofilia A. Una prospettiva multi-stakeholder.","authors":"Matteo Nicola Dario Di Minno, Valentina Drago, Andrea Marcellusi, Salvatore Amato, Consalvo Mattia, Enrico Ferri Grazzi, Filippo Drago, Diego Fornasari","doi":"10.33393/grhta.2025.3618","DOIUrl":"10.33393/grhta.2025.3618","url":null,"abstract":"","PeriodicalId":12627,"journal":{"name":"Global & Regional Health Technology Assessment","volume":"12 ","pages":"256-264"},"PeriodicalIF":0.5,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burden clinico ed economico delle infezioni del tratto urinario nei pazienti con lesioni midollari e sclerosi multipla in Italia.","authors":"Filippo Rumi, Agostino Fortunato, Eugenio Di Brino, Michele Basile, Debora Antonini, Luisa De Palma, Giulio Del Popolo","doi":"10.33393/grhta.2025.3607","DOIUrl":"10.33393/grhta.2025.3607","url":null,"abstract":"","PeriodicalId":12627,"journal":{"name":"Global & Regional Health Technology Assessment","volume":"12 ","pages":"249-255"},"PeriodicalIF":0.5,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12678956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145700637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}