Galician Medical Journal最新文献_第7页

Cytokine Response of CD4+ T-Lymphocytes with Red Rose (Rosa Rosaceae – Pierre de Ronsard) Extracts by in Vitro Evaluation 红玫瑰提取物对CD4+ t淋巴细胞细胞因子反应的体外评价

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Galician Medical Journal Pub Date : 2022-03-01 DOI: 10.21802/gmj.2022.1.5

M. Arokiaraj, E. Menesson

{"title":"Cytokine Response of CD4+ T-Lymphocytes with Red Rose (Rosa Rosaceae – Pierre de Ronsard) Extracts by in Vitro Evaluation","authors":"M. Arokiaraj, E. Menesson","doi":"10.21802/gmj.2022.1.5","DOIUrl":"https://doi.org/10.21802/gmj.2022.1.5","url":null,"abstract":"Background. Red rose extract is known to have anti-inflammatory and immune-modulation effects. In this study, the red rose extract was tested on CD4+T lymphocytes in vitro, and cytokine response was evaluated. \u0000Materials and Methods. The red rose (Rosa Rosaceae - Pierre de Ronsard) extract used in this study was prepared and stored at -20° C until use. CD4+T-cells were seeded in 96-well plates at 313,500 cells/well in 100μ l cell culture medium in duplicate. One-half of the wells were used for biomarker screening in the culture medium, and the other half was used for cytotoxicity assay. Twenty-four hours after plating, the cells were treated in duplicate with 100μ l of the red rose extract diluted at 0.5%, 0.1%, 0.05%, 0.01% and 0.005% (v/v) in the cell culture medium or with culture medium only as control for 72 hours. Some other wells were allocated for untreated cells, and cells treated with the rose extract at 0.005% for 48-h incubation time. \u0000Results. Several cytokines (GRO; IFN-γ; IL-1α, 6, 10; MCP-1; RANTES; TGF-β1; TIMP 1, 2; Ang1, Ang2; G-CSF; MMP-9; and VEGF R2) were elevated. Except for MMP-9, which had fold changes > 2, other cytokines were minimally elevated at various concentrations and timing of rose extract treatment. None of the mentioned cytokines were less than 0.8-fold after treatment with the rose extract. Cytotoxicity assay revealed insignificant changes in the viability of T-cells. \u0000Conclusions. There was a mild elevation in few inflammatory markers by CD4+ T-lymphocytes after in vitro treatment with the red rose extract (Rosa Rosacea - Pierre De Ronsard). Further in vitro and in vivo studies are required to evaluate the benefits of the red rose extract in immune regulation.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47141029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nursing Care Satisfaction among Patients Infected with Covid-19: A Turkish Perspective 2019冠状病毒病患者护理满意度:土耳其视角

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Galician Medical Journal Pub Date : 2022-03-01 DOI: 10.21802/gmj.2022.1.3

Handenur Gündoğdu, F. Tanrıkulu, F. Erol, Ferhat Koç, D. Yılmaz, Y. Dikmen

{"title":"Nursing Care Satisfaction among Patients Infected with Covid-19: A Turkish Perspective","authors":"Handenur Gündoğdu, F. Tanrıkulu, F. Erol, Ferhat Koç, D. Yılmaz, Y. Dikmen","doi":"10.21802/gmj.2022.1.3","DOIUrl":"https://doi.org/10.21802/gmj.2022.1.3","url":null,"abstract":"The aim of this study was to determine the satisfaction with nursing care among patients diagnosed with Covid-19 and related factors. \u0000Materials and Methods. The study was conducted between June and July 2020. The population of the study consisted of 102 patients treated in the Covid-19 clinics of the University Teaching and Research Hospital. The data were collected using the Newcastle Satisfaction with Nursing Care Scale with a total of 19 items, and the Patient Description Form designed to record the sociodemographic characteristics and medical histories. The data were evaluated using the program package IBM SPSS 20.0. To test the significance of the difference between two independent groups, the Student’s t-test was used, and the one-way ANOVA was used to test the significance of the difference between more than two groups. \u0000Results. The results showed that most patients were satisfied with nursing care. A higher level of satisfaction was seen in patients treated in the Covid-19 intensive care units, those with chronic conditions, and those who received information about their health state from nurses. Patients’ family type, sharing fears and worries with nurses, getting information from nurses and the quality of nursing care were the variables significantly associated with patient satisfaction with nursing care. \u0000Conclusions. Satisfaction with nursing care among Covid-19 patients was moderate. When nurses use effective communication skills to meet patients’ care needs, provide patients with adequate information, allow them to express their feelings, and keep them safe, this will further enhance patient satisfaction.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47033049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Diagnostic Accuracy of MR Mammography in Comparison with Digital Mammography and Sonomammography MR乳腺摄影与数字乳腺摄影和超声乳腺摄影的诊断准确性比较

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Galician Medical Journal Pub Date : 2022-03-01 DOI: 10.21802/gmj.2022.1.4

Sreenidhi Sedguli, R. Gowda, Rupa Ranganathan, S. Kumar B.

{"title":"Diagnostic Accuracy of MR Mammography in Comparison with Digital Mammography and Sonomammography","authors":"Sreenidhi Sedguli, R. Gowda, Rupa Ranganathan, S. Kumar B.","doi":"10.21802/gmj.2022.1.4","DOIUrl":"https://doi.org/10.21802/gmj.2022.1.4","url":null,"abstract":"Background. Even though the sensitivity of contrast-enhanced breast magnetic resonance mammography (CE-MRM) is consistently high in the range of 94-100%, conventionally, digital mammography and sonomammography continue as standard imaging modalities for the detection and evaluation of breast disease. \u0000The objective of the study was to detect additional lesions that go undetected by routine digital mammography and sonomammography using CE-MRM. \u0000 Materials and Methods. In a prospective study, 68 patients who came for screening diagnostic mammogram and had breast lesions of Breast Imaging-Reporting and Data System category 3-6 were evaluated. All patients underwent bilateral digital mammography and targeted high-frequency sonomammography of the primary lesion. Those patients who were thought to possibly have breast cancer and to be candidates for surgical management were offered bilateral CE-MRM. \u0000Results. In this prospective study, we included 68 patients (mean age - 50.6 years, range - 30-73 years). A total of 74 lesions were evaluated. In detecting these lesions, digital mammography had a sensitivity of 40.0%, specificity of 100% and diagnostic accuracy of 63.5%. CE-MRM sensitivity was found to be 71.7%, specificity - 96.6% and diagnostic accuracy - 83.7%. Among the 27 additional lesions detected by CE-MRM, histopathological evaluation confirmed only 19, indicating the sensitivity of 100%, specificity of 85.4%, positive predictive value of 67.8%, negative predictive value of 100%, diagnostic accuracy of 89.2%. \u0000 Conclusions. The diagnostic accuracy of CE-MRM was found to be 83.7%, with a specificity of 96.6%. CE-MRM detected 19 additional lesions that were undetected by either digital mammography or ultrasonography. CE-MRM is sensitive in detecting additional malignant lesions which are not detected by other imaging modalities.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48327584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Non-Alcoholic Fatty Liver Disease and Hypothyroidism: Review of Clinical and Experimental Studies 非酒精性脂肪肝与甲状腺功能减退的临床与实验研究综述

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Galician Medical Journal Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.2

Tetiana Ranhulova

引用次数: 1

Comparison of Preclinical Coursework Perception Among Dental Students from India and the Republic of North Macedonia 印度和北马其顿共和国牙科学生临床前课程认知的比较

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Galician Medical Journal Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.6

M. Batra, V. Ambarkova, D. Gijwani, Hansika Popli, Natasa Stavreva, S. Apostolska, Niharika Narang, Tamanna Mutneja, Mira Jankulovska, K. Ivanovski

{"title":"Comparison of Preclinical Coursework Perception Among Dental Students from India and the Republic of North Macedonia","authors":"M. Batra, V. Ambarkova, D. Gijwani, Hansika Popli, Natasa Stavreva, S. Apostolska, Niharika Narang, Tamanna Mutneja, Mira Jankulovska, K. Ivanovski","doi":"10.21802/gmj.2021.4.6","DOIUrl":"https://doi.org/10.21802/gmj.2021.4.6","url":null,"abstract":"Background. The difference in the preclinical curriculum and teaching methodology between European and Southeast Asian countries has a great influence on the process of choosing which education model is predominant and, therefore, students’ opinion on the effectiveness of a preclinical coursework is diverse. \u0000The objective of the research was to assess the perception of the preclinical coursework in prosthodontics, conservative dentistry, and endodontics among Indian and North Macedonian students. \u0000Materials and Methods. This cross-sectional comparative study was carried out among 3rd-year students, final-year students and interns of dental schools of two respective countries. The data were collected in July 2021 using Google Form, a link to which was sent via available social media platforms. The data obtained were analyzed using SPSSv.21.0 (IBM) software. \u0000Results. The data on dental students’ perception of the preclinical coursework were obtained, analyzed, compared, and discussed. A total of 50% of Indian students stated preclinical exercises to be good to get knowledge about treating patients, whereas 47% of North Macedonian students felt the average level of knowledge needed for treating patient. \u0000Conclusions. In this study, the majority of the students were in favor of attending the preclinical course and understood its importance for building up their confidence, better understanding of the subject and better patient handling in future dental practice. However, there were different students’ opinions on the course content, its duration, exercises, faculty interaction, helpfulness of theory lectures that evidence essentiality to view dental studies from a student-centered perspective.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43694869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of Covid-19 Hospital Admissions in Ivano-Frankivsk, Ukraine 乌克兰伊万诺-弗兰基夫斯克新冠肺炎住院人数分析

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Galician Medical Journal Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.1

O. Detsyk, Natalia Fedorkiv, O. Burak, Roksolana Kaluzhna

{"title":"Analysis of Covid-19 Hospital Admissions in Ivano-Frankivsk, Ukraine","authors":"O. Detsyk, Natalia Fedorkiv, O. Burak, Roksolana Kaluzhna","doi":"10.21802/gmj.2021.4.1","DOIUrl":"https://doi.org/10.21802/gmj.2021.4.1","url":null,"abstract":"The Covid-19 pandemic has a substantial impact on socioeconomic, political, demographic, and other aspects of life. Effective healthcare is, however, a primary determinant of successful fighting against Covid-19. The analysis of local healthcare indicators serves as a source for estimating pandemic magnitude and the adaptation of healthcare at a national level. In this study, the rates of Covid-19 hospital admissions to the Ivano-Frankivsk City Hospital, Ukraine, from April 2020 to May 2021 were analysed. All cases were grouped by age, sex, and the type of admission; data were analyzed monthly and seasonally. The peaks of hospital admissions were observed in November 2020 and March 2021; however, the highest mortality rates were seen from August to November 2020. The analysis of age- and sex-disaggregated Covid-19 mortality data showed the predominance of elderly males (61.9%, 66.6 ± 3.9 years) over females (38.1%, 71.8 ± 2.3 years). The ratio of hospital admissions was unstable: the percentage of emergency, GP-referred and self-referred admissions was similar from April to May 2020; however, GP-referred admissions prevailed, and the number of self-referral patients decreased twice between March and May 2021. In conclusions, the trends in hospital admissions were similar to those reported in other studies. However, the differences in time frames and socio-demographic characteristics were observed that highlights the importance of considering regional, social and geographic aspects of the population when improving the capacity of healthcare system and establishing effective preventive measures against the pandemic at the local level.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41627129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monoarthritis of the Elbow Revealing Osteoid Osteoma: A Case Report and Literature Review 显露骨样骨瘤的肘关节单关节炎1例报告及文献复习

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Galician Medical Journal Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.5

N. El Ouardi, S. Sadni, L. Taoubane, A. Mounach, A. Bezza

引用次数: 0

The Effect of Educational Intervention on Care Dependency and Symptom Management After Hematopoietic Stem Cell Transplantation: A Theory-Based Randomized Controlled Study 教育干预对造血干细胞移植术后护理依赖和症状管理的影响:一项基于理论的随机对照研究

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Galician Medical Journal Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.3

T. Menekli, B. Yaprak

{"title":"The Effect of Educational Intervention on Care Dependency and Symptom Management After Hematopoietic Stem Cell Transplantation: A Theory-Based Randomized Controlled Study","authors":"T. Menekli, B. Yaprak","doi":"10.21802/gmj.2021.4.3","DOIUrl":"https://doi.org/10.21802/gmj.2021.4.3","url":null,"abstract":"The objective of the research was to determine the effect of educational intervention based on Bandura’s Social Cognitive Learning Theory on care dependency and symptom management after hematopoietic stem cell transplantation. \u0000Methods. This randomized controlled trial was conducted between January 2019 and February 2020 at the Hematopoietic Stem Cell Transplantation Center. All the patients were randomly divided into two groups: 53 individuals in the intervention group and 53 individuals in the control group. The sociodemographic data collection form, the Edmonton Symptom Assessment Scale and the Care Dependency Scale were used for data collection. Data were collected from the patients one day after hematopoietic stem cell transplantation and 12 weeks later. \u0000Results. There were no statistically significant differences between the groups regarding the mean scores of the Edmonton Symptom Assessment Scale and the Care Dependency Scale at baseline. Twelve weeks after intervention, there were statistically significant differences between the groups regarding the mean scores of the Edmonton Symptom Assessment Scale and the Care Dependency Scale. \u0000Conclusions. Educational intervention along with telephone counseling based on Bandura’s theory was found to be an effective way to reduce symptom severity and care dependency in patients who underwent hematopoietic stem cell transplantation and is recommended for all patients after hematopoietic stem cell transplantation.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47059816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Psychometric Evaluation of the Diabetes Distress Scale in Patients with Type 2 Diabetes in Turkey 土耳其2型糖尿病患者糖尿病痛苦量表的心理测量评估

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Galician Medical Journal Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.4

Nurten Terkeş, H. Bektaş

{"title":"Psychometric Evaluation of the Diabetes Distress Scale in Patients with Type 2 Diabetes in Turkey","authors":"Nurten Terkeş, H. Bektaş","doi":"10.21802/gmj.2021.4.4","DOIUrl":"https://doi.org/10.21802/gmj.2021.4.4","url":null,"abstract":"The objective of the research was to evaluate the validity and reliability of the Diabetes Distress Scale in patients with type 2 diabetes in Turkey. \u0000Materials and Methods. Our study was conducted between September 2016 and January 2017 and included 170 patients with type 2 diabetes. The Personal Information Form and Diabetes Distress Scale were used as a data collection tool. Statistical analysis was performed using SPSS 23.0 and SAS package program. \u0000Results. According to the results of the research, Cronbach’s alpha reliability for the total scale was 0.91. The model fit indices for the revised confirmatory factor analysis model failed to meet the criteria for acceptability: the GFI was 0.8185, the CFI was 0.9316, the Bentler - Bonett (1980) NFI was 0.9005, and the RMSEA was 0.1067. In our study, exploratory factor analysis provided support for the three-factor model: [I] emotional and regimen-related distress, [II] health professional-related distress, [III] diabetes-related interpersonal distress. \u0000Conclusions. When the translation and cultural adaptation process have been considered, the Diabetes Distress Scale is a valid and reliable tool for the Turkish community. It is recommended to be used in the studies and clinical trials.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47793942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Reproducibility of Retinal Nerve Fiber Layer and Macular Thickness Measurements Using Spectral Domain Optical Coherence Tomography 利用光谱域光学相干断层扫描测量视网膜神经纤维层和黄斑厚度的可重复性

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Galician Medical Journal Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.7

A. Sood, R. Paliwal, R. Mishra

{"title":"Reproducibility of Retinal Nerve Fiber Layer and Macular Thickness Measurements Using Spectral Domain Optical Coherence Tomography","authors":"A. Sood, R. Paliwal, R. Mishra","doi":"10.21802/gmj.2021.4.7","DOIUrl":"https://doi.org/10.21802/gmj.2021.4.7","url":null,"abstract":"The objective of the research was to assess the reproducibility of retinal nerve fiber layer (RNFL) and macular thickness using spectral domain optical coherence tomography and to establish whether the same investigator can get the same or similar results when performing the scan thrice in an hour, without reference to the previous scan and the repeat function. \u0000Materials and Methods. In this prospective observational study, 200 subjects who fulfilled the inclusion and exclusion criteria were scanned 3 times according to predefined guidelines at 0, 30 and 60 minutes on the same day, by the same investigator, using spectral domain optical coherence tomography for measurements of RNFL and macular thickness; observations were statistically analyzed and correlated. \u0000 Results. In RNFL thickness, the temporal sector showed the worst reproducibility as compared to other sectors. RNFL was the greatest in the superior quadrant and the thinnest in the temporal quadrant. For macular thickness, the temporal sector (mid zone) showed the worst reproducibility, while in the outer zone, the inferior sector showed the worst reproducibility; macular thickness was the thinnest at the central zone (innermost 1-mm ring), the thickest within the inner 3-mm ring and diminished peripherally. \u0000 Conclusions. RNFL and macular thickness measurements using spectral domain optical coherence tomography by the same observer at 0, 30 and 60 minutes were very reproducible, except for the sectors specifically mentioned. The greater the thickness of the RNFL in any sector the better was the reproducibility in that sector. For macular thickness, the temporal sector (mid zone) showed the worst reproducibility.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45917821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1