Galician Medical Journal最新文献

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Associations Between Chronotype, Adherence to the Mediterranean Diet, and Attitude to Healthy Nutrition 时间类型、坚持地中海饮食和对健康营养态度之间的关系
IF 0.1
Galician Medical Journal Pub Date : 2023-03-01 DOI: 10.21802/gmj.2023.1.2
T. Yalçın, E. E. Ozturk
{"title":"Associations Between Chronotype, Adherence to the Mediterranean Diet, and Attitude to Healthy Nutrition","authors":"T. Yalçın, E. E. Ozturk","doi":"10.21802/gmj.2023.1.2","DOIUrl":"https://doi.org/10.21802/gmj.2023.1.2","url":null,"abstract":"Background. Chronotype is the attitude of a subject in determining the individual circadian preference in behavioral and biological rhythm associated with eating behaviors and health. \u0000Objective. The aim of this study was to evaluate the associations between chronotype, adherence to the Mediterranean diet, and attitudes to healthy nutrition in Turkish adults. \u0000Methods. A survey was conducted online using online platforms. A total of 1,197 volunteers between 18-65 years of age participated in our study. Participants’ adherence to the Mediterranean diet was assessed using the Mediterranean Diet Adherence Screener (MEDAS); their healthy eating attitude and chronotype were assessed using the Attitude Scale for Healthy Nutrition (ASHN) and the Morning-Evening Questionnaire (MEQ), respectively. \u0000Results. Most of the participants were classified as those with an intermediate chronotype. More than half of evening-type participants and nearly half of intermediate-type participants had poor Mediterranean diet adherence. In addition, the percentages of individuals with morning and evening chronotypes in the very low and moderate classification ranges were similar and lower than the percentages of those with an intermediate chronotype. Linear regression analysis revealed that participants with higher MEQ values had higher ASHN and MEDAS scores and a lower body mass index as compared to those with lower MEQ values. \u0000Conclusions. Chronotype was associated with Mediterranean diet adherence and healthy eating attitude. In particular, morning-type subjects showed higher adherence to the Mediterranean diet than intermediate- and evening-type subjects.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48418098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Relationship Between Healthy Lifestyle Beliefs and Hygiene Behaviors of Adolescents During the COVID-19 Pandemic Process 新冠肺炎流行过程中青少年健康生活方式信念与卫生行为的关系
IF 0.1
Galician Medical Journal Pub Date : 2023-03-01 DOI: 10.21802/gmj.2023.1.3
Semra Kose, Arzu Sarıalioğlu, Gulsun Ayran
{"title":"The Relationship Between Healthy Lifestyle Beliefs and Hygiene Behaviors of Adolescents During the COVID-19 Pandemic Process","authors":"Semra Kose, Arzu Sarıalioğlu, Gulsun Ayran","doi":"10.21802/gmj.2023.1.3","DOIUrl":"https://doi.org/10.21802/gmj.2023.1.3","url":null,"abstract":"Aim. The research was carried out to determine the relationship between healthy lifestyle beliefs and hygiene behaviors of adolescents during the COVID 19 pandemic process. \u0000Materials. This descriptive-correlational research was carried out with 418 Turkish adolescents at the age of 13 to 18 years between March and August 2021. The data were collected online with a data collection tool, including a question form, the Healthy Lifestyle Belief Scale for Adolescents (HLBSA), and the Hygiene Behavior Scale (HBS). Percentage, mean, independent sample t-test, Mann-Whitney U-test, Kruskal-Wallis H test, Pearson correlation, and multiple regression analyses were used to analyze the data. \u0000Results. In the study, the variables of socioeconomic status, health perception, and knowledge of healthy living have shown a significant influence on the total HLBSA score; the variables of gender, maternal occupation, health perception and knowledge of healthy living have shown a significant impact on the total HBS score (p< 0.05). The total mean score of the HLBSA was 52.97 ± 19.71, and the total mean score of the HBS was 102.07 ± 23.02. There was a statistically significant relationship between the total HLBSA score and the total HBS score during the COVID-19 epidemic (p < 0.05). \u0000Conclusions. The study found that hygiene behaviors of adolescents during the pandemic process were good if their healthy lifestyle beliefs were good.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43876245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of the Mucinous Component Presence on the Clinical Outcomes of Colorectal Cancer 粘液成分存在对癌症结直肠癌临床转归的影响
IF 0.1
Galician Medical Journal Pub Date : 2022-12-01 DOI: 10.21802/gmj.2022.4.6
I. Ozemir, Muhammed Ali Aydemir, A. Gapbarov, O. Ekinci, O. Alımoglu
{"title":"The Effect of the Mucinous Component Presence on the Clinical Outcomes of Colorectal Cancer","authors":"I. Ozemir, Muhammed Ali Aydemir, A. Gapbarov, O. Ekinci, O. Alımoglu","doi":"10.21802/gmj.2022.4.6","DOIUrl":"https://doi.org/10.21802/gmj.2022.4.6","url":null,"abstract":"Background. The effect of colorectal cancer (CRC) histological subtypes on the prognosis is still a controversial issue. We aimed to compare clinical findings, histopathologic data, and survival outcomes in CRC patients with classical and mucinous subtypes. \u0000Methods. Patients who were operated on for CRC between 2010 and 2017 were included in the study. Patients were classified into two groups according to the presence of a mucinous component: mucinous adenocarcinoma (MAC) - mucinous component > 50% and classical adenocarcinoma (CAC). Clinical and histopathologic findings, recurrence, metastasis, and survival rates were compared. \u0000Results. Data of the 484 CRC patients were documented. Sixty-nine patients (14.3%) were in the MAC group and 415 (85.7%) patients were in the CAC group. The mean age of patients with MAC and CAC was 63.4 ± 13.5 and 68.5 ± 12.7 years, respectively (p = 0.002). Proximal colon localization was found in 30 (43.5%) MAC patients and 123 (29.6%) CAC patients (p = 0.029). The number of patients with metastatic lymph nodes was higher in the MAC group (58% vs. 41.2%, p = 0.03). Nevertheless, there was no significant difference between the CAC and MAC groups in terms of disease-free survival (63.1% vs. 69.6%, p = 0.37) and disease-related mortality (23.6% vs. 23.2%, p = 0.94) over the follow-up period. Multivariate analysis showed that the presence of perineural invasion, patient’s age, and disease stage were associated with mortality in CRC patients. \u0000Conclusions. MACs occurred at a younger age than CACs and were more likely localized in the proximal colon as compared to CACs. Despite increased lymph node metastasis in MAC patients, no statistical significance was detected in overall survival or disease-free survival. Multivariate analysis revealed that age, perineural invasion, and disease stage were relevant to mortality in CRC patients.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48057412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Curcumin Attenuates Lipopolysaccharide-Induced Neuroinflammation and Memory Deficiency by Inhibiting Microglia Activation in Mice Hippocampus 姜黄素通过抑制小鼠海马小胶质细胞激活减轻脂多糖诱导的神经炎症和记忆缺陷
IF 0.1
Galician Medical Journal Pub Date : 2022-12-01 DOI: 10.21802/gmj.2022.4.5
K. Iteire, Raphael Uwejigho, Glory Okonofua
{"title":"Curcumin Attenuates Lipopolysaccharide-Induced Neuroinflammation and Memory Deficiency by Inhibiting Microglia Activation in Mice Hippocampus","authors":"K. Iteire, Raphael Uwejigho, Glory Okonofua","doi":"10.21802/gmj.2022.4.5","DOIUrl":"https://doi.org/10.21802/gmj.2022.4.5","url":null,"abstract":"Background. Curcumin has a variety of properties, including antioxidant and anti-inflammatory ones, and has demonstrated some protective prospects on neurological conditions. \u0000Aim: This study explored the neuroprotective ability of curcumin in lipopolysaccharide-induced neuroinflammation in an animal model. \u0000Methods. A total of thirty-two adult male mice were randomly assigned to four groups (A, B, C, and D, n=8): Group A (Control) received distilled water; Group B was administered lipopolysaccharide (LPS) only to induce neuroinflammation for seven days; Group C was treated with both LPS and curcumin simultaneously for fourteen days; Group D received only curcumin for fourteen days. After appropriate exposure to the mice, their cognitive abilities were assessed using the Y-maze and novel object recognition tests. At the termination of the administration period, the mice were sacrificed, and the hippocampi were dissected for histology and immunostaining using GFAP and Iba1. Statistical analysis for the data generated was done with GraphPad prism. Tests of significance were with one-way ANOVA and Tukey tests for post-hoc. \u0000Results. Curcumin significantly (p < 0.05) increased object recognition, mean alternation, and markedly restored neuronal distortion caused by LPS toxicity in the CA3 region and the dentate gyrus of the hippocampus of Group C animals as compared to Group B. In addition, curcumin significantly down-regulated Iba1 expression and GFAP cell activities of both the CA3 region and the dentate gyrus. \u0000Conclusions. Curcumin showed a promising role in attenuating LPS-induced neuroinflammation in the brain by inhibiting microglial activation and improving memory of neurotoxic mice.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41440255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Neurogenic Myositis Ossificans of the Hip in a Patient with Axonal Polyneuropathy 轴突多发性神经病患者的髋关节神经源性骨化性肌炎
IF 0.1
Galician Medical Journal Pub Date : 2022-12-01 DOI: 10.21802/gmj.2022.4.8
Oubaddi Tlaite, Imrani Kaoutar, Rostoum Soufiane, Moatassim Billah Nabil, Nassar Ittimad
{"title":"Neurogenic Myositis Ossificans of the Hip in a Patient with Axonal Polyneuropathy","authors":"Oubaddi Tlaite, Imrani Kaoutar, Rostoum Soufiane, Moatassim Billah Nabil, Nassar Ittimad","doi":"10.21802/gmj.2022.4.8","DOIUrl":"https://doi.org/10.21802/gmj.2022.4.8","url":null,"abstract":"Background. Neurogenic myositis ossificans is a rare entity defined by the development of soft tissue ossifications in patients with paraplegia or tetraplegia following neurological pathologies, often after cranial or spinal cord trauma. The diagnosis is based on imaging, in particular CT scan, which often reveals the presence of intramuscular ossifications of periarticular location. Treatment is based on analgesics, physiotherapy, and surgery as a last resort. \u0000Case Report. We present a case of neurogenic myositis ossificans in a 26-year-old patient followed for axonal polyneuropathy secondary to vitamin deficiency. \u0000Conclusions. Neurogenic myositis ossificans is a rare entity but is easily diagnosed, given the context of severe neurological disorders and the characteristic appearance on CT scan. In doubtful and atypical cases, a biopsy with histological study is recommended.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45714196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unusual Presentation of “Two-Thirds Tumor” in the Mandible – A Diagnostic Quandary with a Review of the Literature 一个不寻常的“三分之二肿瘤”在下颌骨-诊断的困境与文献回顾
IF 0.1
Galician Medical Journal Pub Date : 2022-12-01 DOI: 10.21802/gmj.2022.4.7
J. T, N. Patil, V. Keluskar, S. M, L. S, Arun Panwar
{"title":"An Unusual Presentation of “Two-Thirds Tumor” in the Mandible – A Diagnostic Quandary with a Review of the Literature","authors":"J. T, N. Patil, V. Keluskar, S. M, L. S, Arun Panwar","doi":"10.21802/gmj.2022.4.7","DOIUrl":"https://doi.org/10.21802/gmj.2022.4.7","url":null,"abstract":"An adenomatoid odontogenic tumor (AOT) is an uncommon benign tumor of the oral cavity commonly found in the maxillary anterior region and is associated with impacted canines in young females. It rarely occurs in the mandibular region with no impacted or missing teeth. A 21-year-old female reported to the clinic with swelling on the right side of the face for the past six months with no history of pain. Radiographic features such as unilocular radiolucency with thinning of the cortical borders and considerable buccal cortical expansion, as well as some evidence of radiopaque specks were noted. Histopathological examination revealed cells with hyperchromatic nuclei, rosette-like structures with focal areas of calcified mass, and concentric rings resembling Liesegang rings, suggestive of AOT. The tumor was treated surgically by enucleation and cauterization. Although follicular type is a common variant, the tumor presented in this case was of extrafollicular type noted in the mandibular canine and premolar regions of a young female patient with no related impacted tooth.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45849015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbiological Assessment of Glycyrrhizic Acid Effectiveness in Bacterial Vaginosis – A Comparative Study 甘草酸治疗细菌性阴道病的微生物学评价——比较研究
IF 0.1
Galician Medical Journal Pub Date : 2022-12-01 DOI: 10.21802/gmj.2022.4.3
S. Ostafiichuk, I. Polishchuk, O. Perkhulyn, O. Kusá, N. Henyk, O. Makarchuk, L. Kurovets, R. Kutsyk
{"title":"Microbiological Assessment of Glycyrrhizic Acid Effectiveness in Bacterial Vaginosis – A Comparative Study","authors":"S. Ostafiichuk, I. Polishchuk, O. Perkhulyn, O. Kusá, N. Henyk, O. Makarchuk, L. Kurovets, R. Kutsyk","doi":"10.21802/gmj.2022.4.3","DOIUrl":"https://doi.org/10.21802/gmj.2022.4.3","url":null,"abstract":"Background. Bacterial vaginosis (BV) is one of the most common female diseases, which is currently characterized by an increasing rate of clinical sign reccurence, the appearance of asymptomatic carriers, and atypical forms. \u0000This study was aimed to evaluate the effectiveness of glycyrrhizic acid administration in the prevention of BV recurrence. \u0000Materials and Methods. The study involved 88 women after BV treatment (metronidazole per os for seven days). Participants were randomly divided into two groups: the main group included 46 patients who were administered 0.1% glycyrrhizic acid intravaginally for three months after the main treatment; the control group comprised 42 women who received no anti-recurrence BV course. The effectiveness was assessed three and six months after the beginning of treatment and included gynecological examination and laboratory assessments (pH, amine test, microbiological investigation). \u0000Results. After recommended BV treatment without anti-recurrence course, the recurrence of laboratory criteria for BV increased three months after the treatment, including the increase in vaginal pH to > 4.5 in all subjects, positive amine test in 35.7% of patients, the presence of Gardnerella vaginalis at a concentration of 104-105 CFU/ml in 31.0% of women, reduction in the frequency of Lactobacillus detection with worsening of the condition and the onset of clinical manifestations of the disease six months later. In the main group, after glycyrrhizic acid administration, laboratory criteria of BV recovery three months after the treatment, and clinical and laboratory markers of BV recovery six months after the treatment were lower as compared to the control group. \u0000Conclusions. The anti-recurrence course of BV (vaginal administration of 0.1% glycyrrhizic acid) demonstrated a decrease in the frequency of complaints, clinical and laboratory markers, stabilization of the species composition of Lactobacillus, and a decrease in facultative anaerobe concentration in the vaginal microbiome as compared to group without anti-recurrence treatment.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47155699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Prognostic Value of Serum Interleukin-6 Level in Hypertensive Patients with COVID-19-Associated Pneumonia 血清白细胞介素-6水平在高血压合并新冠肺炎患者中的预后价值
IF 0.1
Galician Medical Journal Pub Date : 2022-12-01 DOI: 10.21802/gmj.2022.4.2
O. Skakun, S. Fedorov, N. Seredyuk, Olha Verbovska
{"title":"Prognostic Value of Serum Interleukin-6 Level in Hypertensive Patients with COVID-19-Associated Pneumonia","authors":"O. Skakun, S. Fedorov, N. Seredyuk, Olha Verbovska","doi":"10.21802/gmj.2022.4.2","DOIUrl":"https://doi.org/10.21802/gmj.2022.4.2","url":null,"abstract":"Background. An interleukin-6 (IL-6) is a proinflammatory cytokine which plays an important role in COVID-19-associated hyperinflammation. \u0000Aim. This study aimed to assess the predictive ability of serum IL-6 levels for the development of severe/critical clinical conditions, a hypoxemic state requiring supplemental oxygen, and lethal outcomes in patients with COVID-19-associated pneumonia and arterial hypertension (AH). \u0000Materials and Methods. One hundred and thirty-five unvaccinated patients hospitalized for COVID-19-associated pneumonia were enrolled in the study. AH was diagnosed in 78.5% of cases. Pneumonia was confirmed radiologically. SARS-COV-2 as an etiological factor was confirmed by either PCR or ELISA. In addition to conventional laboratory tests, IL-6, ferritin, and soluble interleukin-2 levels were measured. \u0000Results. Among AH patients, the median levels of IL-6 were higher in non-survivors (95.1 [37.8 - 158.8] pg/mL) as compared to survivors (39.5 [13.6 - 81.1] pg/mL) (p=0.04). Among AH patients, the median serum level of IL-6 was 98.3 [37.8 - 158.8] pg/mL in critically ill patients, 41.7 [11.8 - 83.4] pg/mL in severely ill patients, 37.8 [13.6 - 74.4] pg/mL in moderately ill patients (p=0.051). The median serum level of IL-6 was lower at the time of discharge (6.5 [2.0 - 21.5] pg/mL) as compared to that on admission (43.2 [16.1 - 92.0] pg/mL) (p< 0.001). IL-6 level failed to predict severe/critical condition (AUC=0.59, p=0.13) and the need for supplemental oxygen (AUC=0.61, p=0.06); however, it might be used for the prediction of the lethal outcome (AUC=0.69, p=0.03). The cut-off value of IL-6 level for lethal outcome prediction of 91.0 pg/mL showed a sensitivity of 58.3% and a specificity of 78.7%. Patients with IL-6 levels > 91.0 pg/mL on admission had higher odds of lethal outcomes (OR = 4.87 [1.40 - 16.92], p=0.01). \u0000Conclusions. Serum IL-6 level on admission did not show significant predictive ability for severe/critical conditions and hypoxemic states requiring supplemental oxygen in AH patients. However, serum IL-6 levels on admission were higher in non-survivors and might be used for the prediction of lethal outcomes with a cut-off value of 91.0 pg/mL in AH patients.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68360796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 Through the Eyes of a Physiatrist: Back Pain Can Be a Symptom and May Predict Pneumonia in COVID-19 从物理医生的角度看COVID-19:背部疼痛可能是COVID-19的一种症状,并可能预测肺炎
IF 0.1
Galician Medical Journal Pub Date : 2022-12-01 DOI: 10.21802/gmj.2022.4.1
C. Uz
{"title":"COVID-19 Through the Eyes of a Physiatrist: Back Pain Can Be a Symptom and May Predict Pneumonia in COVID-19","authors":"C. Uz","doi":"10.21802/gmj.2022.4.1","DOIUrl":"https://doi.org/10.21802/gmj.2022.4.1","url":null,"abstract":"The study aimed to determine whether back pain is a clinical manifestation in patients with COVID-19 and whether several demographic and disease characteristics could be an effective indicator of back pain. \u0000Materials and Methods. A total of 99 patients with COVID-19 were recruited from the Department of Infectious Diseases of the Kirikkale High Specialized Hospital in Turkey and divided into two groups depending on the presence (n=50) or absence of back pain (n=49). The primary outcomes included were demographic and disease characteristics, the Nord-Trøndelag Health Study Physical Activity Level for Work (HUNT), and the 6-minute walking test. \u0000Results. The most common symptom was fatigue (n=63, 63.6%), followed by back pain (n=50, 50.5%). In the back pain group, the number of patients with sedentary lifestyle, oxygen requirement, pneumonia, and typical pneumonia pattern were significantly higher (p=0.009, p=0.026, p=0.001, p=0.001, respectively), while aerobic capacity was lower (p=0.001). In a logistic regression analysis, back pain was found to be associated with pneumonia presence. \u0000Conclusions. Back pain may be associated with the presence of COVID-19 pneumonia and should be evaluated as its early warning symptom.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43746264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined Effects of Cadmium- and Cyanide-Contaminated Diet on Oxidative Stress Biomarkers in Different Tissues of Rats 镉和氰化物污染饮食对大鼠不同组织氧化应激生物标志物的联合影响
IF 0.1
Galician Medical Journal Pub Date : 2022-10-18 DOI: 10.21802/gmj.2022.4.4
Ovigueroye Ekayoda, H. Kadiri, O. A. Ohwokevwo
{"title":"Combined Effects of Cadmium- and Cyanide-Contaminated Diet on Oxidative Stress Biomarkers in Different Tissues of Rats","authors":"Ovigueroye Ekayoda, H. Kadiri, O. A. Ohwokevwo","doi":"10.21802/gmj.2022.4.4","DOIUrl":"https://doi.org/10.21802/gmj.2022.4.4","url":null,"abstract":"Background. Several toxicants present simultaneously in the environment have combined toxicological effects. In addition, various xenobiotics have distinct effects on oxidative stress biomarkers in animal cells and tissues. \u0000The aim of this study was to analyze the effect of cadmium (Cd) and cyanide (CN) through the food chain on some antioxidant indices in the tissues (lungs, testes, heart, and brain) of male Wistar rats. \u0000Materials and Methods. The study included sixty African catfish allocated to four groups, each comprising fifteen fish, treated with potassium cyanide (KCN) and cadmium chloride (CdCl2), held at a temperature of 25°C in a 100-litre fish tank aquarium with water contaminated with 0.4 mg of both cyanide and cadmium/100 ml of water. All the fish were later killed, dried, and used to prepare diet for experimental animals. Twenty male rats divided into four groups, each comprising five rats, were used for this study as well, and fed for 28 days as follows: Group A - control diet; Group B - cyanide-contaminated diet; Group C - cadmium-contaminated diet; Group D - diet contaminated with cyanide + cadmium. Subsequently, they were sacrificed. Biochemical analysis of the tissues excised from the rats was done. \u0000Results. There was a significant (p < 0.05) increase in lipid peroxidation level and a significant decrease in superoxide dismutase, catalase and reduced glutathione activities in the lungs, testes, heart, and brain of rats fed a catfish diet containing both cyanide and cadmium as compared to controls. In addition, contaminated diet altered acetylcholinesterase activity in the brain, glutathione peroxidase activity, glutathione-S-transferase activity, and glutathione reductase activity in the tissues of experimental rats. \u0000Conclusions. Cadmium and cyanide, via the food chain, induce oxidative stress in the lungs, testes, heart, and brain of rats.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47691794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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