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A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION最新文献

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Heterogeneity of Elderly Asthmatics Unveiled by Phenotyping/Endotyping of a Brazilian Sample 通过巴西样本的表型/内分型揭示老年哮喘患者的异质性
A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2558
M. Menezes, L. Yamamoto, A. Cetlin, M. Ferriani, O. Trevisan Neto, J. Melo, M. E. Zanetti, L. Arruda, E. Vianna
{"title":"Heterogeneity of Elderly Asthmatics Unveiled by Phenotyping/Endotyping of a Brazilian Sample","authors":"M. Menezes, L. Yamamoto, A. Cetlin, M. Ferriani, O. Trevisan Neto, J. Melo, M. E. Zanetti, L. Arruda, E. Vianna","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2558","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2558","url":null,"abstract":"","PeriodicalId":124606,"journal":{"name":"A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115222977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epigenetic Training of the Interleukin 6 Gene in Airway Epithelial Cells Is Central to Asthma Exacerbations 气道上皮细胞中白细胞介素6基因的表观遗传训练是哮喘加重的核心
A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2553
L. Lunding, M. Weckmann, U. Zissler, R. Bodenstein-Sgro, S. Webering, R. Fernandez Ceballos, S. Nemani, B. Oliver, C. Vermeulen, M. van den Berge, C. Ober, A. Kuenstner, Heiner Busch, I. König, G. Christoph, C. Schmidt‐Weber, A. Yildirim, T. Bahmer, G. Hansen, E. von Mutius, K. Rabe, A. Dittrich, B. Schaub, M. Kopp, M. Wegmann, ALLIANCE Study Group as part of the German Center
{"title":"Epigenetic Training of the Interleukin 6 Gene in Airway Epithelial Cells Is Central to Asthma Exacerbations","authors":"L. Lunding, M. Weckmann, U. Zissler, R. Bodenstein-Sgro, S. Webering, R. Fernandez Ceballos, S. Nemani, B. Oliver, C. Vermeulen, M. van den Berge, C. Ober, A. Kuenstner, Heiner Busch, I. König, G. Christoph, C. Schmidt‐Weber, A. Yildirim, T. Bahmer, G. Hansen, E. von Mutius, K. Rabe, A. Dittrich, B. Schaub, M. Kopp, M. Wegmann, ALLIANCE Study Group as part of the German Center ","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2553","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2553","url":null,"abstract":"","PeriodicalId":124606,"journal":{"name":"A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125534667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Targeting Reprogrammed Glycolysis in Aspergillus Fumigatus-activated Lung Eosinophils and Alveolar Macrophages for the Treatment of Severe Asthma 针对烟曲霉激活的肺嗜酸性粒细胞和肺泡巨噬细胞的重编程糖酵解治疗严重哮喘
A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2538
Phyllis X L Gan, W. Liao, H. Lim, W. Wong
{"title":"Targeting Reprogrammed Glycolysis in Aspergillus Fumigatus-activated Lung Eosinophils and Alveolar Macrophages for the Treatment of Severe Asthma","authors":"Phyllis X L Gan, W. Liao, H. Lim, W. Wong","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2538","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2538","url":null,"abstract":"","PeriodicalId":124606,"journal":{"name":"A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129150928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circulating Natural Killer Cell Immunophenotypes Correlate With Severe Asthma Clinical Traits 循环自然杀伤细胞免疫表型与严重哮喘临床特征相关
A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2554
M. Duvall, T. Chiha, R. Reilly, S.K. Ramdour, N. Krishnamoorthy, R. Cagnina, W. Phipatanakul, D. Mauger, B. Phillips, E. Israel, B. Levy
{"title":"Circulating Natural Killer Cell Immunophenotypes Correlate With Severe Asthma Clinical Traits","authors":"M. Duvall, T. Chiha, R. Reilly, S.K. Ramdour, N. Krishnamoorthy, R. Cagnina, W. Phipatanakul, D. Mauger, B. Phillips, E. Israel, B. Levy","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2554","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2554","url":null,"abstract":"","PeriodicalId":124606,"journal":{"name":"A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION","volume":"165 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132150855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Airway Efficacy and Systemic Activity With Different Inhaled Corticosteroid-containing Dosing Regimens in Patients With Persistent Asthma: A Structured Literature Review and Modeling Analysis 持续性哮喘患者不同吸入含皮质类固醇剂量方案的气道疗效和全身活性:结构化文献综述和模型分析
A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2560
D. Singh, P. Daley-Yates, J. Igea, L. Macchia, M. Verma, N. Berend, M. Plank
{"title":"Airway Efficacy and Systemic Activity With Different Inhaled Corticosteroid-containing Dosing Regimens in Patients With Persistent Asthma: A Structured Literature Review and Modeling Analysis","authors":"D. Singh, P. Daley-Yates, J. Igea, L. Macchia, M. Verma, N. Berend, M. Plank","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2560","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2560","url":null,"abstract":"","PeriodicalId":124606,"journal":{"name":"A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117076003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Rhinovirus Infection and Th17 Cell Conditioning on Airway Epithelial Expression of IL-1β, TNF-α, IL-17C and GCSF and Neutrophil Activation in T2-low Vs T2-high Asthma 鼻病毒感染和Th17细胞调节对t2low Vs t2high哮喘患者气道上皮IL-1β、TNF-α、IL-17C和GCSF表达及中性粒细胞活化的影响
A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2545
E. Vanderwall, L. M. Rich, M. White, S. Ziegler, J. Debley
{"title":"Impact of Rhinovirus Infection and Th17 Cell Conditioning on Airway Epithelial Expression of IL-1β, TNF-α, IL-17C and GCSF and Neutrophil Activation in T2-low Vs T2-high Asthma","authors":"E. Vanderwall, L. M. Rich, M. White, S. Ziegler, J. Debley","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2545","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2545","url":null,"abstract":"","PeriodicalId":124606,"journal":{"name":"A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION","volume":"471 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130633517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epithelial Immunomodulation by Aerosolized Toll-like Agonists Prevents Allergic Lung Inflammation by Reducing Th2 Polarization 通过减少Th2极化，雾化toll样激动剂对上皮细胞的免疫调节可预防过敏性肺部炎症
A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2546
M. Ntita, M. K. Longmire, Y. Wang, J. Pantaléon-García, V. Kulkarni, E.E. Scott
{"title":"Epithelial Immunomodulation by Aerosolized Toll-like Agonists Prevents Allergic Lung Inflammation by Reducing Th2 Polarization","authors":"M. Ntita, M. K. Longmire, Y. Wang, J. Pantaléon-García, V. Kulkarni, E.E. Scott","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2546","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2546","url":null,"abstract":"","PeriodicalId":124606,"journal":{"name":"A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION","volume":"1157 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134255042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pattern of Allergic Sensitization in Lagos, Nigeria: Informing Cost Effective Testing for a Low Resource Setting 在拉各斯，尼日利亚的过敏致敏模式:为低资源设置通知成本有效的测试
A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2555
S. Dede, O. Ojo, C. Agwu, O. Ozoh
{"title":"Pattern of Allergic Sensitization in Lagos, Nigeria: Informing Cost Effective Testing for a Low Resource Setting","authors":"S. Dede, O. Ojo, C. Agwu, O. Ozoh","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2555","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2555","url":null,"abstract":"","PeriodicalId":124606,"journal":{"name":"A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125455094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IL-13 Regulated Airway Epithelial Genes Correlate to Lung Function and Markers of T2 Asthma in Sarpiii Participants IL-13调节的气道上皮基因与Sarpiii参与者肺功能和T2哮喘标志物相关
A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2547
J. Boomer, G. Kim, A. Lehman, J. Fahy, A. Alsup, N. Jarjour, S. Christenson, B. Gaston, P. Woodruff, E. Bleecker, D. Meyers, W. Moore, E. Israel, B. Levy, D. Mauger, S. Erzurum, S. Wenzel, Abhik Ray, M. Castro
{"title":"IL-13 Regulated Airway Epithelial Genes Correlate to Lung Function and Markers of T2 Asthma in Sarpiii Participants","authors":"J. Boomer, G. Kim, A. Lehman, J. Fahy, A. Alsup, N. Jarjour, S. Christenson, B. Gaston, P. Woodruff, E. Bleecker, D. Meyers, W. Moore, E. Israel, B. Levy, D. Mauger, S. Erzurum, S. Wenzel, Abhik Ray, M. Castro","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2547","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2547","url":null,"abstract":"","PeriodicalId":124606,"journal":{"name":"A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117089571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preventive Effects of Inhibition of Thymic Stromal Lymphopoietin on Bronchial Hyperresponsiveness and Inflammatory Cellular Pattern in an Experimental Model of Chronic Allergic Pulmonary Inflammation Exacerbated by Lipopolysaccharide 胸腺基质淋巴生成素抑制对脂多糖加重慢性变应性肺部炎症实验模型支气管高反应性和炎症细胞模式的预防作用
A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2551
E. A. Grencheski, B.Q.S. Lopes, E. Cruz, R. Righetti, T. Santos, L. Camargo, F. Almeida, B. Saraiva-Romanholo, C. Prado, S. Bezerra, P. A. Pigati, F. Lopes, E. Leick, I. Tibério
{"title":"Preventive Effects of Inhibition of Thymic Stromal Lymphopoietin on Bronchial Hyperresponsiveness and Inflammatory Cellular Pattern in an Experimental Model of Chronic Allergic Pulmonary Inflammation Exacerbated by Lipopolysaccharide","authors":"E. A. Grencheski, B.Q.S. Lopes, E. Cruz, R. Righetti, T. Santos, L. Camargo, F. Almeida, B. Saraiva-Romanholo, C. Prado, S. Bezerra, P. A. Pigati, F. Lopes, E. Leick, I. Tibério","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2551","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2551","url":null,"abstract":"","PeriodicalId":124606,"journal":{"name":"A101. LINKING BIOLOGY TO THE REAL WORLD IN ASTHMA AND ALLERGIC INFLAMMATION","volume":"352 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131723085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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