Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft最新文献_第2页

[Current state of implantation of flexible intraocular lenses]. 【柔性人工晶体植入术的现状】。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

R Menapace

{"title":"[Current state of implantation of flexible intraocular lenses].","authors":"R Menapace","doi":"","DOIUrl":"","url":null,"abstract":"Two main arguments have stimulated the development of hydrogel and silicone lenses: flexibility allows folding and thus insertion through a small incision, and inertness promises excellent biocompatibility, possibly surpassing that of PMMA. However, as long-term performance remains to be established, these implants cannot yet be considered a routine alternative. Clinical studies are mandatory to document their advantages and any disadvantages, especially as few of the reports already published on experience with such lenses do not give an objective picture of the current status: the surgical techniques used and the observation criteria applied differ and were sometimes inappropriate. In addition, the series are too small and the follow-up studies too short to allow valid conclusions. In this paper, following the description of the materials and designs and of the implantation techniques available for flexible lenses, a review of the pertinent literature and the author's own experiences is reported. This is based on 800 implantations performed over a period of 4 years. Monobloc designs with flange haptics (IOGEL, STAAR) have been found to perform best. The Faulkner folder has proved to be optimal, allowing for easy and atraumatic folding and insertion. Within the eye, the lens is safely guided and released. Bag placement of appropriately styled lens models is strongly recommended, since sulcus-placed lenses have sometimes shown either iris bulging or decentration and windshield-wiper or propeller phenomena. The capsular edge should be smooth and the capsular opening well centered and round in order to guarantee stable fixation and symmetrical compression.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 5","pages":"421-8"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12920661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Thrombospondin and its importance in proliferative retinal diseases]. 血栓反应蛋白及其在增殖性视网膜疾病中的重要性。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

P Esser, M Weller, K Heimann, P Wiedemann

{"title":"[Thrombospondin and its importance in proliferative retinal diseases].","authors":"P Esser, M Weller, K Heimann, P Wiedemann","doi":"","DOIUrl":"","url":null,"abstract":"Thrombospondin (TSP), a platelet-derived protein of the integrin-binding family with adhesive and mitogenic properties was localized in surgically obtained epiretinal traction membranes from patients with traumatic (7/8) and idiopathic (8/8) proliferative vitreoretinopathy (PVR) and proliferative diabetic retinopathy (PDR) (6/8). Using double-label immunofluorescence techniques, we demonstrated co-localization of TSP with the endothelial cell marker, von Willebrand factor, in PDR; however, only a minority of labeled macrophages showed simultaneous staining for TSP. Therefore, macrophages are probably not a major source of TSP in PVR. We demonstrated co-distribution of blood coagulation factor XIII and two of its cross-linking substrates, fibronectin and TSP, in epiretinal membranes, as well as the detection of plasmin and presumably plasmin-induced TSP breakdown products in physiologic and pathologic vitreous. These results suggest that the coagulation system has a functional role in proliferative retinal disorders and imply that the application of inhibitors of the coagulation cascade like heparin may be a potential therapeutic approach.","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 4","pages":"337-40"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12950568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Structure and dynamics of photo-acoustic shock-waves in 193 nm excimer laser photo-ablation of the cornea]. [193 nm准分子激光角膜光烧蚀的光声冲击波结构与动力学]。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

O Kermani, H Lubatschowski

引用次数: 0

[Therapy of retinal detachment in Coats' disease]. 【Coats病视网膜脱离的治疗】。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

C Berzas, G Richard

引用次数: 0

[Immunologic suppression of experimental autoimmune uveitis]. 实验性自身免疫性葡萄膜炎的免疫抑制

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

S R Thurau, R R Caspi, C C Chan, H L Weiner, R B Nussenblatt

引用次数: 0

[Planimetric follow-up of cytomegalovirus retinitis treated with ganciclovir in patients with AIDS]. 更昔洛韦治疗艾滋病患者巨细胞病毒性视网膜炎的平面随访

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

J Garweg, M Böhnke, H J Stellbrink

引用次数: 0

[Fluorescence angiography image of erythrocytes with the scanning laser ophthalmoscope]. 【激光扫描检眼镜的红细胞荧光血管造影图像】。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

J E Nasemann

{"title":"[Fluorescence angiography image of erythrocytes with the scanning laser ophthalmoscope].","authors":"J E Nasemann","doi":"","DOIUrl":"","url":null,"abstract":"Erythrocytes bind fluorescein to their surface, but they do not take up the dye intracellularly during fluorescein angiography. The cells are therefore hypofluorescent compared to blood plasma. Due to the high velocity of red blood cells in retinal vessels, this phenomenon has not been observed during conventional angiography. Scanning laser ophthalmoscopy, however, allows imaging of the retina with a very high temporal resolution. The exposure time of the scanning laser beam for a single erythrocyte is in the range of only 100 ns. Therefore, scanning laser ophthalmoscopy permits imaging of fast-moving red blood cells in large retinal vessels. Pathologically reduced blood flow is clearly visible and can be measured with digital image analysis. The values found in three patients with vascular occlusions were between 0.1 and 1.8 mm/s. In cases with intact circulation, digital image analysis was not sufficient to measure red blood cell velocity. Even if a velocimeter that permits semiquantitative comparison between erythrocytes and moving black dots is used, superimposed on the angiogram, reliable results can only be obtained in cases with reduced red cell velocity. Nevertheless, for the clinician observation of erythrocyte flow during scanning laser angiography is a new and fascinating tool.","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 2","pages":"138-41"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13017931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Development of lens opacities in a period of 6 months after pneumatic retinopexy]. 【气动视网膜固定术后6个月内晶状体混浊的发展】。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

F Koch, M Spitznas, T Böker, M Mougharbel, D Ohlhorst, O Hockwin

引用次数: 0

[Persistence of Chlamydia trachomatis in patients with chronic therapy refractory conjunctivitis]. 慢性难治性结膜炎患者沙眼衣原体的持续存在。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

E M Haller, G Langmann, A Langmann, H Lerchner

{"title":"[Persistence of Chlamydia trachomatis in patients with chronic therapy refractory conjunctivitis].","authors":"E M Haller, G Langmann, A Langmann, H Lerchner","doi":"","DOIUrl":"","url":null,"abstract":"We report three patients with recurrent Chlamydia-associated conjunctivitis. The clinical course of the Chlamydial infection was documented by positive conjunctival smears (direct immunofluorescence staining) and the evaluation of the IgA-titer in the sera (immunoperoxidase assay). The recovery of the ocular symptoms after therapy onset correlated well with the negative results of the conjunctival smears and the decrease in IgA level in the sera. The recurrence of the conjunctivitis was accompanied by an increase in the IgA titer in the sera of all three patients and the presence of Chlamydial elementary bodies in the conjunctival scrapings in two cases. Three patients showed immunologic pecularities: two had an allergic diathesis; the third patient developed Wegener disease 3 months after the onset of ocular inflammation. Inclusion bodies or Chlamydial DNA can persist in conjunctival cells. Anderson suggested that a recurrence of active Chlamydial infection may be induced by external causes, which lead to reconstitution of elementary bodies from the persisting DNA. The extraordinary immune situation of our patients might be one cause of the recurrent conjunctivitis.","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 3","pages":"248-51"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13050505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Effect of prednisolone on the course of optic neuritis. Results of a double-blind study]. 强的松龙对视神经炎病程的影响。一项双盲研究的结果]。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

S Trauzettel-Klosinski, E Aulhorn, H C Diener, C Minder, D Pfluger

{"title":"[Effect of prednisolone on the course of optic neuritis. Results of a double-blind study].","authors":"S Trauzettel-Klosinski, E Aulhorn, H C Diener, C Minder, D Pfluger","doi":"","DOIUrl":"","url":null,"abstract":"The treatment of optic neuritis (ON) with corticosteroids has been controversial for many years. None of the previous studies with the usual dosage of steroids or ACTH has proven that this therapy is beneficial. However, these studies did not apply sensitive parameters for assessing the course of ON. The aim of this study was to examine the effect of corticosteroids using subtle parameters. The study design emphasized: 1. strict criteria for patient selection; 2. frequent controls during the initial period of the disease, follow-up for 1 year; 3. double-blind conditions with randomized groups; 4. assessment of the course with sensitive parameters, including visual acuity, visual evoked potentials (VEP) and the Tübingen Flikker Test, also called the Aulhorn Flicker Test, which monitors the activity of the ON. These last two tests were used for the first time in a controlled treatment study in ON. Thirty-eight patients with acute ON were treated orally in a double-blind procedure with either methylprednisolone (initially 100 mg daily, reduction every 3 days) or with vitamin B1 (100 mg thiamin daily) in the control group. The results of the Flicker Test and VEP showed a trend toward faster recovery under prednisolone within the first few weeks after onset of the disease. After 1 year none of the parameters examined showed any difference between the two groups. Thus, although prednisolone treatment in the dosage mentioned above seems to speed up recovery in the initial phase in some patients, no long-term benefit could be demonstrated.","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 5","pages":"490-501"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12919897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0