Med Phoenix最新文献_第7页

Cardiovascular Manifestations of Primary Hypothyroidism 原发性甲状腺功能减退症的心血管表现

Med Phoenix Pub Date : 2022-02-16 DOI: 10.3126/medphoenix.v6i2.36794

Samrat Shrestha, K. Lamsal, Bhakta Dev Shreshtha, Sunny Bajracharya

{"title":"Cardiovascular Manifestations of Primary Hypothyroidism","authors":"Samrat Shrestha, K. Lamsal, Bhakta Dev Shreshtha, Sunny Bajracharya","doi":"10.3126/medphoenix.v6i2.36794","DOIUrl":"https://doi.org/10.3126/medphoenix.v6i2.36794","url":null,"abstract":"Introduction\u0000Hypothyroidism is clinical syndrome that results from decreased secretion of thyroid hormone from thyroid gland. Primary Hypothyroidism accounts for 90-95% of all cases of hypothyroidism. Hypothyroidism has various cardiovascular manifestations. With aim for early prevention and management of cardiovascular manifestation in hypothyroidism this study was conducted.\u0000Materials and Methods\u0000A cross sectional observational study was conducted in Department of Medicine in Bir Hospital. Ethical clearance from Institutional Review Board, National Academy of Medical Sciences was taken. A total of 70 patients with untreated Primary Hypothyroidism were randomly selected without any prior known comorbidities or under any medication. Data were collected and entered in Microsoft Excel to tabulate data and analyse results.\u0000Results\u0000Out of 70 enrolled participants, 41 cases were subclinical hypothyroidism and 29 overt/clinical hypothyroidism with 80% female and 20% male. Most common presenting cardiovascular symptoms was peripheral odema (60%) followed by easy fatiguability (47.14%). Body Mass Index (BMI) and Hypertension was higher in majority of cases 70% and 60% respectively. Dyslipidemia was present in 48.57% of cases among which majority changes were in triglyceride and total cholesterol level. Abnormality in ECG were seen in only 22.85% of cases with T wave abnormality (18.57%) being most common followed by sinus bradycardia (14.28%). Echocardiography was abnormal in 7.14% of cases with 2.86% showing pericardial effusion.\u0000Conclusion\u0000Cardiovascular manifestations were present in majority of patients of primary hypothyroidism especially High BMI, Hypertension and Dyslipidemia. Screening of newly diagnosed primary hypothyroidism for cardiovascular manifestations thus should be done routinely in all patients.","PeriodicalId":123544,"journal":{"name":"Med Phoenix","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124026268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Iron Deficiency in Anemic Patients: Study in a Tertiary Care Centre 贫血患者缺铁:三级保健中心的研究

Med Phoenix Pub Date : 2022-02-16 DOI: 10.3126/medphoenix.v6i2.37070

A. Chaurasiya, F. Alam, A. K. Patel, Sourav Manna, N. K. Singh

{"title":"Iron Deficiency in Anemic Patients: Study in a Tertiary Care Centre","authors":"A. Chaurasiya, F. Alam, A. K. Patel, Sourav Manna, N. K. Singh","doi":"10.3126/medphoenix.v6i2.37070","DOIUrl":"https://doi.org/10.3126/medphoenix.v6i2.37070","url":null,"abstract":"Introduction\u0000Anemia is a clinical abnormality characterized by a reduction in hemoglobin concentration below the normal for age and sex. It can be of different types, the most common being iron deficiency anemia which affects mostly pregnant and lactating females and growing children in the developing world.\u0000Materials and Methods\u0000This was a hospital-based observational study conducted at National Medical College and Teaching Hospital, Pathology Department, Birgunj, Nepal. Patients above the age of 10 years of both sexes (male and females) having anemia ( males having hemoglobin level < 13 gm/dl and females having hemoglobin level < 12 gm/dl ) were included. After a detailed history, preliminary blood tests including complete blood counts, peripheral smear, and reticulocytes count were done. In patients suspected (microcytic hypochromic blood picture and normal reticulocytes count ) to have iron deficiency anemia, serum ferritin was done to confirm the diagnosis. Patients under the age of 10 years and those patients having blood malignancies (acute or chronic leukemia) were excluded from the study.\u0000Results\u0000Sixty anemic patients were found to have iron deficiency. Females were affected more (66%) with iron deficiency anemia than males (34%). There were two peaks (30% and 21%) in age groups 10 – 20 years and 61 – 70 years. Complete blood counts revealed a significant decrease in the value of red cell indices like mean corpuscular volume in 70% patients (Normal MCV 80 to 100 fl) and mean corpuscular hemoglobin in 72% patients (Normal MCH 27 to 33 pg ). On peripheral smear, it was seen that most of the patients (72%) had microcytic hypochromic blood pictures. Iron deficiency anemia was more common in rural areas.\u0000Conclusion\u0000Iron deficiency anemia was the most common type of anemia. It is more common in females and the prevalence is more in rural areas.","PeriodicalId":123544,"journal":{"name":"Med Phoenix","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125441346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nasopharyngolaryngoscopy in the Diagnosis of Various Pathologies of the Larynx in a Tertiary Care Hospital. 鼻咽喉镜在三级医院各种喉部病理诊断中的应用。

Med Phoenix Pub Date : 2022-02-16 DOI: 10.3126/medphoenix.v6i2.37502

K. Shrestha, B. Shrestha, M. Pokharel, A. Dhakal

{"title":"Nasopharyngolaryngoscopy in the Diagnosis of Various Pathologies of the Larynx in a Tertiary Care Hospital.","authors":"K. Shrestha, B. Shrestha, M. Pokharel, A. Dhakal","doi":"10.3126/medphoenix.v6i2.37502","DOIUrl":"https://doi.org/10.3126/medphoenix.v6i2.37502","url":null,"abstract":"Introduction:\u0000Laryngeal disorders are frequently encountered in ENT practice. Nasopharyngolaryngoscopy is an outpatient department procedure that is used for the diagnosis and management of laryngeal disorders. The objective so the study was to study the prevalence of different laryngeal disorders by the use of Nasopharyngolaryngoscopy as an outpatient department procedure in ENT.\u0000Materials and Methods:\u0000A hospital-based prospective and analytical study was conducted in the department of ENT at Dhulikhel hospital, Kathmandu University Hospital during the period of 2 years. A total of 132 patients, who had various laryngeal symptoms and underwent NPL were included in this study. A careful and detailed history and clinical examination of the patients was done. Data were recorded and analyzed.\u0000Results\u0000A total of 132 patients with various laryngeal symptoms underwent Nasopharyngolaryngoscopy. Among them, 54.5% (72) were male and 45.5% (60) were female. The age range was from 18-84 years. The most common laryngeal disorder observed was Laryngopharyngeal reflux disease, followed by chronic laryngitis, true vocal cord nodule, and true vocal cord polyp.\u0000Conclusion\u0000Nasopharyngolaryngoscopy is a safe outpatient department procedure that is helpful for the diagnosis and management of various laryngeal disorders.","PeriodicalId":123544,"journal":{"name":"Med Phoenix","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125643161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Renal Artery Dimensions and Variation on Computed Tomography Angiogram: A Cross-sectional Study. 肾动脉尺寸和计算机断层血管造影的变化:一项横断面研究。

Med Phoenix Pub Date : 2022-02-16 DOI: 10.3126/medphoenix.v6i2.38371

O. Panta, Vivek Dhakal, Shahjan Raj Giri, Bibek Gurung, R. Ghimire

{"title":"Renal Artery Dimensions and Variation on Computed Tomography Angiogram: A Cross-sectional Study.","authors":"O. Panta, Vivek Dhakal, Shahjan Raj Giri, Bibek Gurung, R. Ghimire","doi":"10.3126/medphoenix.v6i2.38371","DOIUrl":"https://doi.org/10.3126/medphoenix.v6i2.38371","url":null,"abstract":"Introduction\u0000A knowledge of renal artery dimension is necessary for characterizing the physiological change as well as pathological process undergoing in the renal artery likely stenosis, ectasia, or aneurysm. This study aims to explore the anatomy of the renal artery with regards to its dimension, relation, and branching and identify the common anatomical variation.\u0000Materials and Methods\u0000The study was a retrospective hospital record-based study conducted during the period of one year from 2019 January to 2019 December. All abdominal CT angiograms were reviewed for renal artery anatomy and variation. Abnormal Abdominal CT angiograms were excluded from the study. Normal anatomy, dimensions, and variation of renal vasculature were assessed.\u0000ResultsA total of 110 patients included the inclusion criteria and was included in the study. The renal length and size of the renal artery were significantly larger on the left side. The renal artery diameter showed positive correlation with renal length (r= 0.432; p<0.001). No variation of the renal size of renal artery diameter was however noted with sex. Supernumerary arteries were seen in 33(30%) patients. The optimum cut-off value of renal artery diameter for predicting accessory renal artery was 5.35 or less which yielded a sensitivity of 75% and specificity of 70%. (AUC-0.79; p<0.001). When 4.15 mm was taken as cut-off, the specificity increased to 96% with a marked reduction in sensitivity to 3.6%.\u0000Conclusion\u0000Renal artery diameter is dependent on laterality, kidney size, and presence of accessory artery and independent of sex.","PeriodicalId":123544,"journal":{"name":"Med Phoenix","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131646863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Leprosy in Post Elimination Era 麻风病在后消灭时代

Med Phoenix Pub Date : 2022-02-16 DOI: 10.3126/medphoenix.v6i2.42540

V. Paudel, Brijesh Shrestha

引用次数: 0

Diagnostic Dilemma During Laparoscopic Cystectomy of Twisted Serous Cystadenofibroma of Ovary in Adolescent Girl – A Case Report with Literature Review 青春期女孩卵巢扭曲浆液性囊腺纤维瘤腹腔镜胆囊切除术诊断困境1例并文献复习

Med Phoenix Pub Date : 2022-02-16 DOI: 10.3126/medphoenix.v6i2.37176

S. Kayastha, Jamuna Kiran Paudel, R. Deo, Hari Om Joshi, Sweta Thapa

引用次数: 0

Comparison Between Single Dose Versus Multiple Doses Antibiotics in Laparoscopic Cholecystectomy 腹腔镜胆囊切除术中单剂量与多剂量抗生素的比较

Med Phoenix Pub Date : 2022-02-16 DOI: 10.3126/medphoenix.v6i2.37503

U. Yadav, A. Raya, P. Bhatta, B. Rai, A. Yadav, Sanjiv Kumar Shahi

{"title":"Comparison Between Single Dose Versus Multiple Doses Antibiotics in Laparoscopic Cholecystectomy","authors":"U. Yadav, A. Raya, P. Bhatta, B. Rai, A. Yadav, Sanjiv Kumar Shahi","doi":"10.3126/medphoenix.v6i2.37503","DOIUrl":"https://doi.org/10.3126/medphoenix.v6i2.37503","url":null,"abstract":"Introduction: Laparoscopic cholecystectomy is clean-contaminated surgery. Prophylactic antibiotics are used to reduce SSI but there is still controversy regarding use of antibiotics in postoperative period. The aim of this study is to compare the effect of single dose versus multiple doses of antibiotics in terms of wound infection.\u0000Methods: This prospective study was carried out in department of surgery of National Medical College and Teaching Hospital, Birgunj from March 2020 to March 2021. Patients with diagnosis of symptomatic cholelithiasis were divided alternatively in single dose (SD) group and multiple doses (MD) group. SD group were given injection ceftriaxone 1gm at the time of induction of anaesthesia and MD group received injection ceftriaxone 1gm at the time induction of anaesthesia and followed by continuation of same dose twice a day for 2 days.\u0000Results: A total of 249 patients were enrolled in the study. Among 249 patients, 127 patients were in the single dose (SD) group and 122 patients in (MD) group. The mean age of patient was 37.37±14.30 years with minimum age of 13 years and maximum 75 years. In single dose (SD) group, 5(3.9%) patients developed wound infection and 3(2.5%) patients in multiple (MD) group developed wound infection which was not statistically significant (p=0.437)\u0000Conclusion: Single dose antibiotic was found as effective as multiple doses of antibiotics in terms of wound infection in laparoscopic cholecystectomy.","PeriodicalId":123544,"journal":{"name":"Med Phoenix","volume":"223 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127452042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Profile, Precipitating Factors and Outcome of Hepatic Encephalopathy in Patients with Liver Cirrhosis 肝硬化肝性脑病的临床特点、诱发因素及预后

Med Phoenix Pub Date : 2021-07-19 DOI: 10.3126/MEDPHOENIX.V6I1.36796

S. Bhattarai, D. Karki

{"title":"Clinical Profile, Precipitating Factors and Outcome of Hepatic Encephalopathy in Patients with Liver Cirrhosis","authors":"S. Bhattarai, D. Karki","doi":"10.3126/MEDPHOENIX.V6I1.36796","DOIUrl":"https://doi.org/10.3126/MEDPHOENIX.V6I1.36796","url":null,"abstract":"Introduction: Hepatic encephalopathy (HE) is characterized by reversible neuropsychological features and is observed with advanced and decompensated cirrhosis of the liver. Patients outcomes and survival depends on clinical presentation, identification of the precipitating factor, early management, and treatment of complications. This study aims to find out the clinical profile of cirrhotic patients with hepatic encephalopathy, their precipitating factors, and clinical outcomes in patients admitted at a tertiary care Teaching Hospital in Gandaki province, Nepal. \u0000Materials and Methods: An observational, cross-sectional, hospital-based prospective study comprising of 140 cirrhotic patients with encephalopathy was conducted over a study period of 18 months. Their clinical profile, precipitating factors, and outcomes during hospitalization including mortality were studied. The data analysis was done using SPSS version 20 and a P-value of ≤0.05 was considered significant. \u0000Results: Majority (36.5%) of the patients presented with Grade II HE. Upper gastrointestinal (GI) bleeding and spontaneous bacterial peritonitis were the most common precipitating factors. Inpatient mortality was 22.9%. The increased mortality rate was observed in patients with Child class C and with higher grading (Grade III and IV) of hepatic encephalopathy and in presence of more than two precipitating factors \u0000Conclusion: Most of the patients presented with Grade II HE. Upper gastrointestinal bleed and infections were the most common precipitating factors. Patients with Hepatic encephalopathy of Grades III and IV, those with CTP Child class C, and in presence of more than two precipitating factors have high mortality.","PeriodicalId":123544,"journal":{"name":"Med Phoenix","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116572708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Posterior Reversible Encepalopathy Syndrome in A Child With Post Streptococcal Glomerulonephritis- A Rare Case Report 儿童链球菌感染后肾小球肾炎后可逆性脑病综合征-一例罕见病例报告

Med Phoenix Pub Date : 2021-07-19 DOI: 10.3126/MEDPHOENIX.V6I1.36781

Sunita Ghimire, S. Shrestha, R. Bastola, A. Dahal, P. Shakya

引用次数: 0

Bilateral Post-typhoid Retinitis: A Case Report 双侧伤寒后视网膜炎1例

Med Phoenix Pub Date : 2021-07-19 DOI: 10.3126/MEDPHOENIX.V6I1.34638

K. Subedi, Smita Shrestha, A. Manandhar

引用次数: 0