European Spine Journal最新文献

{"title":"Early clinical experience with a new supercritical CO₂ virus-inactivated bone paste allograft in cervical interbody fusion.","authors":"Jean Charles Le Huec, Thibault Cloche, Wendy Thompson, Grégoire Edorh, Lisa Boue, Stéphnae Bourret","doi":"10.1007/s00586-025-08851-8","DOIUrl":"https://doi.org/10.1007/s00586-025-08851-8","url":null,"abstract":"<p><strong>Study design: </strong>Prospective, single-center study OBJECTIVE: To assess the efficacy, tolerance, and safety of BIOBank supercritical CO₂-treated bone paste for cervical interbody arthrodesis using grafts and plates.</p><p><strong>Materials and methods: </strong>This was a prospective, single-center, observational clinical study of 49 individuals (72 grafted levels) undergoing anterior cervical discectomy and fusion (ACDF) with interbody cages and grafting with a novel bone paste (BIOBank Synergy^®, France) with fixation plates. The clinical and radiographic outcomes were evaluated at 3, 12, and 24 months.</p><p><strong>Results: </strong>The mean (SD) NDI improved significantly from 41.3 (17.0) preoperatively to 22.2 (19.7) at 24 months (p < 0.001). Median (IQR) neck pain significantly improved from 6.0 (3.0) preoperatively to 0 (4.0) at 24 months (p < 0.001), and median arm pain significantly improved from 3.25 (2.5) preoperatively to 0.0 (0.0) at 24 months (p < 0.001). In terms of quality of life, the mean physical score significantly improved from 37.8 (8.6) preoperatively to 45.1 (11.0) (p < 0.001) at 24 months. The cumulative fusion rate at 24 months post-operatively was 96.7%. Surgical ease of handling was excellent (9.9 ± 0.5 points/10 maximum). There were no graft-related serious adverse events.</p><p><strong>Conclusions: </strong>This first clinical study of BIOBank bone paste shows that the material is acceptable to surgeons and results in good functional, radiological, and outcomes for patients requiring anterior cervical arthrodesis combined with interbody grafting with a fixation plate.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Announcements.","authors":"","doi":"10.1007/s00586-025-08928-4","DOIUrl":"https://doi.org/10.1007/s00586-025-08928-4","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterising patients undergoing surgery for lumbar spinal stenosis associated neurogenic claudication in the UK: what does the British Spinal Registry tell us?","authors":"Lianne Wood, Rebecca Hunter, Esther Williamson, Khalid M Salem, Opinder Sahota, Bethan E Phillips, Paul Hendrick, Sarah E Lamb","doi":"10.1007/s00586-025-09000-x","DOIUrl":"https://doi.org/10.1007/s00586-025-09000-x","url":null,"abstract":"<p><strong>Purpose: </strong>Surgery for lumbar spinal stenosis (LSS) has a variable outcome with many not returning to pre-condition activity levels. We aimed to explore the (1) baseline characteristics of UK patients undergoing surgery, and (2) association of patient characteristics with a clinically important improvement in the 6-month Oswestry Disability Index (ODI) in a population defined by previously developed LSS criteria.</p><p><strong>Methods: </strong>We used data from the British Spinal Registry (BSR) (2012-2023). Anonymised data included demographics, patient reported outcome measures (PROMs) (ODI; visual analogue scale (VAS) for back and leg pain); quality of life (EQ-5D)) at baseline, and 6-weeks and 6-months post-surgery, surgical procedure, surgery duration and intra-operative blood loss. We used descriptive and multivariate analyses to estimate the association between variables and the minimum clinically important difference (MCID) (30% improvement from baseline) in 6-month disability (ODI). MCIDs define the smallest benefit of value to patients. We explored differences in baseline values between 6-month responders and the total database, and between primary and revision surgery.</p><p><strong>Results: </strong>In 6801 patients sampled from the BSR the mean age was 70.5 (SD 9.1), 51% (3452/6794) were female, and most were from higher socioeconomic areas (mean Index of Multiple Deprivation rank 84.3, SD 38.8). Preoperatively most had severe disability (ODI 48.7, SD 17.5), moderate leg (VAS 7.0, SD 2.4) and back pain (VAS 6.3, SD 2.5). Proportionally 58% (1160/2008) of the 6-month responders achieved the MCID in ODI. Higher baseline back pain intensity (odds ratio (OR) 0.9, 95%CI 0.9, 0.9), revision surgery (OR 0.5 95%CI 0.3, 0.8), higher 6-week leg pain intensity (OR 0.9, 95%CI 0.8, 1.0) and severe 6-week disability (OR 0.3, 95%CI 0.2, 0.5) reduced the odds of achieving the MCID in 6-month ODI.</p><p><strong>Conclusions: </strong>Patients undergoing surgery in the UK are severely disabled prior to surgery. The available data suggests that 42% of UK patients do not achieve a clinically important improvement in 6-month disability.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simplified sagittal slice HU measurement as a practical alternative to conventional axial HU in opportunistic osteoporosis screening.","authors":"Akihiko Hiyama, Daisuke Sakai, Hiroyuki Katoh, Masato Sato, Masahiko Watanabe","doi":"10.1007/s00586-025-09013-6","DOIUrl":"https://doi.org/10.1007/s00586-025-09013-6","url":null,"abstract":"<p><strong>Purpose: </strong>Opportunistic assessment of bone quality using CT-derived Hounsfield Unit (HU) values has gained attention as an alternative to DXA-based osteoporosis screening. However, conventional axial HU measurements are time-consuming and operator-dependent. A simplified sagittal HU measurement method may provide a more practical approach, although its clinical validity has yet to be fully established. This study aimed to evaluate the correlation between HU values obtained from simplified sagittal and conventional axial slices and determine their respective diagnostic performance in identifying osteoporosis.</p><p><strong>Methods: </strong>We retrospectively analyzed 162 patients aged ≥ 50 years who underwent both lumbar spine CT and DXA scans. HU values were measured using both conventional axial slices (Ax L1-4 Ave HU) and a simplified sagittal slice method (Sg L1-4 Ave HU). Spearman's rank correlation was calculated to assess the association between each HU measurement and the lowest T-score (Low-T score). Agreement between the two methods was evaluated using Bland-Altman analysis, and the predictive performance for diagnosing osteoporosis (Low T-score ≤ - 2.5) was assessed by ROC curve analysis. Vertebra-specific differences between axial and sagittal HU values were also analyzed.</p><p><strong>Results: </strong>Sg L1-4 Ave HU showed a moderate correlation with Low T-score (ρ = 0.476), comparable to Ax L1-4 Ave HU (ρ = 0.493). The Bland-Altman analysis revealed a mean difference of - 4.08 HU between Sg and Ax measurements, with most differences falling within the 95% limits of agreement. Axial HU values were consistently higher than sagittal HU values across all lumbar levels, particularly at L1 and L4. The AUC for predicting osteoporosis was 0.692 for Sg L1-4 Ave HU and 0.707 for Ax L1-4 Ave HU. Based on Youden's index, the optimal cutoff values were 94.0 HU for sagittal and 99.5 HU for axial measurements.</p><p><strong>Conclusions: </strong>Simplified sagittal HU measurements demonstrated good agreement with conventional axial measurements and exhibited similar diagnostic accuracy in identifying osteoporosis. Given their efficiency and consistency, sagittal HU values may serve as a practical and reproducible alternative for CT-based opportunistic bone quality assessment, especially in routine clinical settings or where DXA is unavailable.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to percutaneous pedicle screw placement with a mini-open decompression versus open surgery in the treatment of lumbar spondylolisthesis: one-year results of a randomised controlled trial.","authors":"A E H Broekema, C D Schenck, J F C Wolfs, B Torensma, G C W de Ruiter, J M A Kuijlen, M P Arts","doi":"10.1007/s00586-025-08989-5","DOIUrl":"https://doi.org/10.1007/s00586-025-08989-5","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Back and pelvic girdle pain from prepregnancy to postpartum: a new pain tracking method considering pain intensity and chronological patterns.","authors":"Tetsuhiro Iguchi, Kenichiro Kakutani, Hiroo Souda, Keisuke Kinoshita, Natsuko Funada, Masaki Tomatsuri, Takashi Sadamitsu, Takashi Yurube","doi":"10.1007/s00586-025-08954-2","DOIUrl":"https://doi.org/10.1007/s00586-025-08954-2","url":null,"abstract":"<p><strong>Purpose: </strong>To identify differences in severe pain levels during prepregnancy to four months postpartum among groups along with risk factors for residual pain early in pregnancy.</p><p><strong>Methods: </strong>We examined 298 patients who participated in the questionnaire. Pain intensity was evaluated using a numerical rating scale (NRS) monthly postpartum. Four patterns emerged: recovery group (n = 200), with NRS 0-3 at 4 months postpartum; keep-high group (n = 20), with NRS ≥ 6 every month after delivery; worse group (n = 28), where NRS increased ≥ 3 during months 1-4; and mixed group (n = 50). Age, body mass index (BMI), history of back pain, breastfeeding, feeding posture, depression, and postpartum stress factors were compared.</p><p><strong>Results: </strong>Overall, 15% patients had pain with NRS ≥ 4 before pregnancy and 33% at 4 months postpartum. NRS score of the keep-high group was the highest (4.18) before pregnancy, with a distinctive pain pattern. For participants with NRS ≥ 4 before pregnancy, the odds ratio of NRS ≥ 7 in the final month was 5.56 [95% confidence interval: 2.52-12.58, p < 0.001]. All three groups compared with the recovery group demonstrated significant differences in the questionnaires for depression (p < 0.01) and postpartum stress factors (p < 0.05). The combination of lower back and back pain was an early indicator of severe postpartum pain.</p><p><strong>Conclusion: </strong>Higher NRS scores before pregnancy and at multiple pain sites are early indicators of severe postpartum pain. All three groups, except the recovery group, showed a tendency for depression. However, the mixed group exhibited features similar to the recovery group.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative assessment of lumbar posterior anatomy on axial t2-weighted MR imaging: a comprehensive analysis of muscle-bone interval and spinous process muscle-ligaments complex.","authors":"Guanyi Liu, Shuping Cai, Changting Wu, Lu Mao, Yizhong Ma, Weihu Ma, Yong Hu, Qing Li, Lushuang Ye","doi":"10.1007/s00586-025-09009-2","DOIUrl":"https://doi.org/10.1007/s00586-025-09009-2","url":null,"abstract":"<p><strong>Objective: </strong>To quantitatively evaluate the lumbar posterior anatomy, specifically the muscle-bone interval (MBI) and spinous process muscle-ligament complex, using magnetic resonance imaging (MRI) and investigate their clinical significance in surgical approaches.</p><p><strong>Methods: </strong>140 patients (70 males and 70 females, aged 20 to 90 years) underwent lumbar spine MRI. Measurements of the MBI and spinous process, including length, width, height, and cross-sectional area, were taken at each lumbar level from L2 to L5 using ImageJ open-source software.</p><p><strong>Results: </strong>The MBI was confirmed along the midline plane of the spinous processes at the L2-L5 levels. The mean values for the MBI's length, width, height, and cross-sectional area were 20.43 ± 4.44 mm, 10.63 ± 3.18 mm, 12.81 ± 2.99 mm, and 77.57 ± 47.89 mm², respectively. Notably, multifidus muscle (MFM) decreases with age, while MBI increases, with males showing larger MFM and smaller MBI than females. These anatomical features exhibited a gradual increase from L2 to L5.</p><p><strong>Conclusions: </strong>We identified the MBI as a significant anatomical space between the MFM, lamina, and the spinous processes, with its prominence increasing in the lower lumbar regions. The MBI expands with age, particularly its cross-sectional area, while the MFM cross-sectional area diminishes. These anatomical changes have notable implications for surgical approaches, including the potential refinement of posterior midline approaches to enhance muscle preservation and surgical outcomes.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a deep learning-powered system for multi-version global alignment and proportion score to predict mechanical complications after adult degenerative scoliosis surgery.","authors":"Qifeng Lan, Shanshan Liu, Cheng Zhang, Chenyi Guo, Yiming Shi, Jian He, Xingyu Zhou, Jiaheng Shang, Qiang Qi, Zhaoqing Guo, Zhuoran Sun, Siyu Zhou, Ji Wu, Nanfang Xu, Weishi Li","doi":"10.1007/s00586-025-08995-7","DOIUrl":"https://doi.org/10.1007/s00586-025-08995-7","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Answer to the Letter to the Editor of W. Yue, et al. concerning \"A multimodal machine learning model integrating clinical and MRI data for predicting neurological outcomes following surgical treatment for cervical spinal cord injury\" by Shimizu T, et al. (Eur Spine J [2025]: doi: 10.1007/s00586-025-08873-2).","authors":"Tomoaki Shimizu","doi":"10.1007/s00586-025-09021-6","DOIUrl":"https://doi.org/10.1007/s00586-025-09021-6","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor concerning \"A multimodal machine learning model integrating clinical and MRI data for predicting neurological outcomes following surgical treatment for cervical spinal cord injury\" by Shimizu T, et al. (Eur Spine J [2025]: doi: 10.1007/s00586-025-08873-2).","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1007/s00586-025-09018-1","DOIUrl":"https://doi.org/10.1007/s00586-025-09018-1","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}