{"title":"The effect of pelvic incidence on age-related changes in spinopelvic sagittal alignment in older individuals: a longitudinal study for 10 years.","authors":"Yu Yamato, Tomohiko Hasegawa, Go Yoshida, Tomohiro Banno, Hideyuki Arima, Shin Oe, Koichiro Ide, Tomohiro Yamada, Yusuke Murakami, Yukihiro Matsuyama","doi":"10.1007/s00586-025-09136-w","DOIUrl":"https://doi.org/10.1007/s00586-025-09136-w","url":null,"abstract":"<p><strong>Purpose: </strong>Spinopelvic sagittal alignment is a critical determinant of the quality of life and clinical outcomes in older adults. Although pelvic incidence (PI) is a well-established morphological parameter influencing spinopelvic alignment, its role in age-related alignment changes and compensatory mechanisms remains incompletely understood. This study aimed to investigate the influence of PI magnitude on 10-year changes in spinopelvic sagittal alignment and compensatory adaptations in a community-dwelling older population.</p><p><strong>Methods: </strong>We analyzed 135 adults (mean age: 68.5 years in 2012) who underwent whole-spine lateral radiography between 2012 and 2022. Participants were classified into three groups based on their 2012 PI values: Low PI, Mid PI, and High PI. Radiographic parameters, including thoracic kyphosis (TK), upper and lower lumbar lordosis, sacral slope, pelvic tilt (PT), and sagittal vertical axis (SVA), were compared longitudinally. Changes in alignment were assessed, and compensatory mechanisms were evaluated in relation to PI magnitude.</p><p><strong>Results: </strong>Regardless of PI magnitude, participants demonstrated pelvic retroversion and kyphotic changes in the upper lumbar spine over the 10-year period. However, compensatory strategies differed among the groups. Individuals with low PI exhibited increased TK and compensatory hyperlordosis in the lower lumbar region. Conversely, those with high PI showed decreased TK and progressive kyphotic changes in the lower lumbar spine. Notably, no significant group differences were observed in SVA or PT progression.</p><p><strong>Conclusion: </strong>PI magnitude significantly influences compensatory mechanisms associated with age-related deterioration of spinopelvic alignment. These findings highlight the need for individualized evaluation and management strategies based on PI morphology in aging populations.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor concerning \"relationship between posterior paraspinal muscle fat infiltration and early conversion to lumbar spinal fusion following decompression surgery\" by Chiapparelli E, et al. (Eur spine J [2025]: doi: 10.1007/s00586-025-09030-5).","authors":"Jiajun Deng, Yongchun Xiao","doi":"10.1007/s00586-025-09148-6","DOIUrl":"https://doi.org/10.1007/s00586-025-09148-6","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suzanne McIlroy, Yee Mah, Vassilios Tahtis, Abigail Beddard, Lindsay Bearne, John Weinman, Sam Norton
{"title":"Minimal clinically important difference of the 6-Minute walk test and daily step count at 3 months following surgery for lumbar spinal stenosis.","authors":"Suzanne McIlroy, Yee Mah, Vassilios Tahtis, Abigail Beddard, Lindsay Bearne, John Weinman, Sam Norton","doi":"10.1007/s00586-025-09085-4","DOIUrl":"https://doi.org/10.1007/s00586-025-09085-4","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to estimate the minimal clinically important difference (MCID) in two objective measures of walking: 6-minute walk distance (6MWD) and mean daily step count in patients with lumbar spinal stenosis, three months post-surgery. Both anchor-based and distribution-based approaches were used to support result robustness and comparability.</p><p><strong>Methods: </strong>97 patients (mean age 70 ± 8.3 years; 50 female) were recruited from three UK hospitals. 6MWD (metres) and mean daily step count (measured over 7 days with an accelerometer), and self-rated clinical questionnaires were assessed pre- and 12-weeks post-surgery. The anchor-based method used the Oswestry Disability Index (ODI) and the satisfaction subscale of the Zurich Claudication Questionnaire. Receiver-operating characteristic (ROC) curve analysis was used to determine the optimal cutoff points for MCIDs for changes in the 6MWD and step count. The distribution-based method used 0.3 SD of the change scores.</p><p><strong>Results: </strong>Anchor-based MCIDs for the 6MWD were 26 m (ODI) and 35 m (walking satisfaction). The step count MCID could not be determined using the ODI but was 680 steps when anchored to satisfaction. The distribution-based method estimated MCIDs of 34 m for the 6MWD and 750 steps for step count.</p><p><strong>Conclusion: </strong>Even modest improvements in walking capacity and daily step count may be meaningful to patients recovering from LSS surgery. Further research is needed to validate the MCID for daily step count however, the identified MCIDs for the 6MWD (26-35 m) and daily step count (680-750 steps) provide practical thresholds for assessing meaningful change and can be used to inform goal setting within rehabilitation.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk factors for new vertebral fracture after percutaneous vertebroplasty or kyphoplasty for osteoporotic vertebral compression fractures (OVCFs): an updated systematic review and meta-analysis.","authors":"Yan-Shiang Lian, Lei-Po Chen, Ji-Ying Chen","doi":"10.1007/s00586-025-09082-7","DOIUrl":"https://doi.org/10.1007/s00586-025-09082-7","url":null,"abstract":"<p><strong>Purpose: </strong>Osteoporotic vertebral compression fractures (OVCFs) are common in older persons, and percutaneous vertebroplasty (PVP) and kyphoplasty (PKP) are effective minimally invasive treatments. This systematic review and meta-analysis aim to update knowledge on risk factors associated with NVCF after these procedures.</p><p><strong>Methods: </strong>PubMed, EMBASE, and the Cochrane Library were searched to December 2023 for studies evaluating risk factors for NVCF after PVP and PKP, using the following keywords: \"osteoporotic vertebral compression fractures,\" \"percutaneous vertebral augmentation,\" \"vertebroplasty\", \"kyphoplasty,\" \"new vertebral fracture,\" and \"risk factor\". Eligible studies included randomized controlled trials (RCTs), prospective and retrospective studies, and case-control studies. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to derive summary effects. Heterogeneity among the studies was assessed using the I<sup>2</sup> statistic.</p><p><strong>Results: </strong>Fifteen studies including a total of 6,546 patients were analyzed. Significant risk factors for new vertebral fractures (NVCF) following PVP and PKP were older age (adjusted OR [aOR] = 1.08, 95% CI: 1.01-1.15), female sex (aOR = 2.11, 95% CI: 1.60-2.79), a higher number of treated vertebrae (aOR = 2.27, 95% CI: 1.18-4.35), and cement leakage (aOR = 3.43, 95% CI: 2.17-5.41). No statistical significances on the associations between bone mineral density (BMD), body mass index (BMI) with NVCF were observed.</p><p><strong>Conclusion: </strong>Significant risk factors for NVCF after PVP and PKP include older age, female sex, higher number of treated vertebrae, and cement leakage. The findings highlight the importance of careful patient selection to minimize the risk of NVCF.</p><p><strong>Level of evidence: </strong>IV.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk factors for adjacent vertebral fracture after kyphoplasty or percutaneous vertebroplasty in osteoporotic vertebral systematic review and meta-analysis compression fractures.","authors":"Lei He, Wei Li, Xingpeng Zhai, Zhiwei Li","doi":"10.1007/s00586-025-09111-5","DOIUrl":"https://doi.org/10.1007/s00586-025-09111-5","url":null,"abstract":"<p><strong>Objective: </strong>To systematically evaluate the risk factors of adjacent vertebral re-fracture after percutaneous vertebroplasty and percutaneous kyphoplasty for osteoporotic vertebral compression fractures.</p><p><strong>Methods: </strong>PubMed, Embase, The Cochrane Library, Web of Science, CNKI, Wanfang, VIP, CBM and other databases were searched by computer to collect case-control studies on adjacent vertebral re-fracture after vertebroplasty for osteoporotic vertebral compression fractures. The retrieval time was from the establishment of the database to July 17,2024. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Meta-analysis was performed using Stata 17.0 software.</p><p><strong>Results: </strong>A total of 26 articles were included, including 7604 patients. The results of Meta-analysis showed that postoperative bone cement leakage, excessive recovery rate of vertebral height, too little or too much bone cement injection, low bone mineral density, high recovery rate of anterior vertebral height, no anti-osteoporosis treatment after operation, too many injured vertebrae, previous history of fracture, older age and female patients were risk factors for AVCF. High level of bone cement distribution index, physical exercise after operation and low BMI index are protective factors for AVCF.</p><p><strong>Conclusion: </strong>There are many risk factors for adjacent vertebral re-fracture after vertebroplasty for osteoporotic vertebral compression fractures. Medical staff should make comprehensive assessment, prevention and intervention.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bernhard Heimkes, Nina Berger, Vincent Frimberger, Bronek Boszczyk, Miguel Pishnamaz, Heide Delbrück
{"title":"Normative values of the sagittal lumbopelvic alignment in children during the first decade of life : A retrospective observational study from a German paediatric orthopaedic hospital.","authors":"Bernhard Heimkes, Nina Berger, Vincent Frimberger, Bronek Boszczyk, Miguel Pishnamaz, Heide Delbrück","doi":"10.1007/s00586-025-09107-1","DOIUrl":"https://doi.org/10.1007/s00586-025-09107-1","url":null,"abstract":"<p><strong>Purpose: </strong>Normal values for lumbopelvic sagittal alignment in prepubertal non-Asian children have rarely been reported. However, they are becoming increasingly important for treating of hip and spinal disorders in this age group.</p><p><strong>Methods: </strong>Standing lateral radiographs of the lumbar spine and pelvis of children aged 3-10 years from 2016 to 2024 from a German paediatric orthopaedic hospital with defined inclusion criteria were evaluated in terms of pelvic incidence (PI), lumbar lordosis (LL), pelvic tilt (PT), and sacral slope (SS). The results were compared with those of comparable studies. Parametric and non-parametric statistical tests, as well as linear correlation and regression analyses, were performed according to the characteristics of the variables.</p><p><strong>Results: </strong>X-rays of 54 children aged 7.8 ± 1.9 years (30 boys, 24 girls, 44 children aged 7-10 years) were included. The mean [± standard deviation (SD)] of LL, PI, PT, and SS were 47.7°±11.2°, 35.8°±7.1°, 5.6°±7.1°, and 30.2°±8.3°, respectively. There were no significant differences between the genders and no age dependencies in our sample. The following significant correlations were observed: PI vs. LL (r = 0.393), PI vs. SS (r = 0.580), PI vs. PT (r = 0.307), SS vs. LL (r = 0.755), SS vs. PT (r=-0.586), and LL vs. PT (r=-0.534). The linear regression analysis yields the following equations: LL = 0.6 PI + 26.35 (R<sup>2</sup> = 0.155; p = 0.006), PT = 0.31 PI - 5.41 (R<sup>2</sup> = 0.094; p = 0.024) and SS = 0.68 PI + 5.86 (R<sup>2</sup> = 0.337; p < 0.001). The measured parameters were not significantly different from those of the Chinese studies, whereas the PI, LL, and SS of the only comparable non-Asian study were significantly higher.</p><p><strong>Conclusion: </strong>This study adds normal values for lumbopelvic alignment parameters in children aged 3-10 years. Differences and similarities in the parameters and their possible influencing variables between the studies published to date call for further studies, especially with the most likely influencing variables of bone age, percentile curves, body composition, and X-ray technique.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endplate Hounsfield units outperform lumbar HU and VBQ in predicting cage subsidence after posterior lumbar interbody fusion: a retrospective cohort study.","authors":"Sheyang Xu, Xingling Liu, Xianglong Meng","doi":"10.1007/s00586-025-09062-x","DOIUrl":"https://doi.org/10.1007/s00586-025-09062-x","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anthony N Baumann, Robert J Trager, Omkar Anaspure, Maria LaMontagne, Gordon Preston, Keegan T Conry, Jacob C Hoffmann
{"title":"Answer to Letter to the Editor of L. Dai, et al. concerning \"The association between postoperative physical therapy and opioid prescription after posterior lumbar interbody fusion: a retrospective cohort study of United States academic health centers\" by Baumann AN, et al. (Eur Spine J [2025]: doi: 10.1007/s00586-025-08824-x).","authors":"Anthony N Baumann, Robert J Trager, Omkar Anaspure, Maria LaMontagne, Gordon Preston, Keegan T Conry, Jacob C Hoffmann","doi":"10.1007/s00586-025-09145-9","DOIUrl":"https://doi.org/10.1007/s00586-025-09145-9","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giovanni Viroli, Alberto Ruffilli, Matteo Traversari, Mohammadreza Chehrassan, Javad Moeini, Marco Manzetti, Marco Ialuna, Cesare Faldini
{"title":"What factors predict cervical sagittal alignment restoration after correction of thoracic adolescent idiopathic scoliosis with severe thoracic hypokyphosis? A multicenter retrospective study of 57 patients.","authors":"Giovanni Viroli, Alberto Ruffilli, Matteo Traversari, Mohammadreza Chehrassan, Javad Moeini, Marco Manzetti, Marco Ialuna, Cesare Faldini","doi":"10.1007/s00586-025-09131-1","DOIUrl":"https://doi.org/10.1007/s00586-025-09131-1","url":null,"abstract":"<p><strong>Purpose: </strong>to evaluate changes in cervical sagittal alignment after correction of AIS with severe thoracic hypokyphosis (< 10°); to assess radiographical parameters predicting postoperative cervical sagittal alignment through multivariate regression analysis.</p><p><strong>Methods: </strong>A multicenter retrospective study included AIS patients with severe thoracic hypokyphosis. Treatment involved posterior spinal fusion with pedicle screws, Ponte osteotomies, differential rod contouring and DVR. Radiographic analysis was conducted preoperatively and at a minimum 2-year follow-up.</p><p><strong>Results: </strong>Among 57 patients, a significant improvement in T5-T12 thoracic kyphosis was noted at the last follow-up. Cervical Lordosis (CL) also significantly increased, with a remaining mismatch between ideal and actual postoperative CL. Correlation analyses revealed associations between thoracic kyphosis and postoperative CL. In patients with preoperative neutral or kyphotic CL, additional factors, such as TK apex-SVA, C5-T2° Change, and TK apex-scoliosis apex distance, correlated with CL changes.</p><p><strong>Conclusion: </strong>Posterior correction of hypokyphotic AIS demonstrated significant CL improvement, yet a mismatch between ideal and achieved alignment persisted. The degree of thoracic and cervicothoracic alignment restoration correlated with spontaneous CL improvement. Overall, the study highlights the complexities of sagittal alignment in AIS.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor concerning \"the CASINO trial: surgical versus Conservative management in patients with cervical radiculopathy due to intervertebral disc herniation: a prospective cohort study\" by Gül A, et al. (Eur spine J [2025]: doi: 10.1007/s00586-025-09045-y.","authors":"Yang Zhang, Anqi Sun, Xiujuan Qian","doi":"10.1007/s00586-025-09121-3","DOIUrl":"https://doi.org/10.1007/s00586-025-09121-3","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}