European Urology Open Science最新文献

{"title":"P087 Comprehensive evaluation of androgen receptor pathway inhibitor monotherapy in prostate cancer: Safety, oncologic outcomes, and quality of life – a systematic review and meta-analysis","authors":"Fazekas T., Kói T.S., Miszczyk M., Giesen A., Matsukawa A., Zattoni F., Rodriguez-Sanchez L., Szarvas T., Rivas J.G.M., Nyirády P.T., Shariat S.F., Gandaglia G., Rajwa P.","doi":"10.1016/S2666-1683(24)01215-1","DOIUrl":"10.1016/S2666-1683(24)01215-1","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"69 ","pages":"Pages 105-106"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P083 PSMA RNA aptamer a10-3.2Iindocyanine green chimeric enables immediate fluorescence tracking of prostate cancer","authors":"Mulati Y., Cong L., Jiawen L., Cheng L., Kewei X.","doi":"10.1016/S2666-1683(24)01211-4","DOIUrl":"10.1016/S2666-1683(24)01211-4","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"69 ","pages":"Page 100"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Capabilities of ChatGPT-3.5 as a Urological Triage System","authors":"Christopher Hirtsiefer ,&nbsp;Tim Nestler ,&nbsp;Johanna Eckrich ,&nbsp;Henrieke Beverungen ,&nbsp;Carolin Siech ,&nbsp;Cem Aksoy ,&nbsp;Marianne Leitsmann ,&nbsp;Martin Baunacke ,&nbsp;Annemarie Uhlig","doi":"10.1016/j.euros.2024.10.015","DOIUrl":"10.1016/j.euros.2024.10.015","url":null,"abstract":"<div><h3>Background and objective</h3><div>Patients struggle to classify symptoms, which hinders timely medical presentation. With 35–75% of patients seeking information online before consulting a health care professional, generative language–based artificial intelligence (AI), exemplified by ChatGPT-3.5 (GPT-3.5) from OpenAI, has emerged as an important source. The aim of our study was to evaluate the role of GPT-3.5 in triaging acute urological conditions to address a gap in current research.</div></div><div><h3>Methods</h3><div>We assessed GPT-3.5 performance in providing urological differential diagnoses (DD) and recommending a course of action (CoA). Six acute urological pathologies were identified for evaluation. Lay descriptions, sourced from patient forums, formed the basis for 472 queries that were independently entered by nine urologists. We evaluated the output in terms of compliance with the European Association of Urology (EAU) guidelines, the quality of the patient information using the validated DISCERN questionnaire, and a linguistic analysis.</div></div><div><h3>Key findings and limitations</h3><div>The median GPT-3.5 ratings were 4/5 for DD and CoA, and 3/5 for overall information quality. English outputs received higher median ratings than German outputs for DD (4.27 vs 3.95; <em>p</em> &lt; 0.001) and CoA (4.25 vs 4.05; <em>p</em> &lt; 0.005). There was no difference in performance between urgent and non-urgent cases. Analysis of the information quality revealed notable underperformance for source indication, risk assessment, and influence on quality of life.</div></div><div><h3>Conclusion and clinical implications</h3><div>Our results highlights the potential of GPT-3.5 as a triage system for offering individualized, empathetic advice mostly aligned with the EAU guidelines, outscoring other online information. Relevant shortcomings in terms of information quality, especially for risk assessment, need to be addressed to enhance the reliability. Broader transparency and quality improvements are needed before integration into, primarily English-speaking, patient care.</div></div><div><h3>Patient summary</h3><div>We looked at the performance of ChatGPT-3.5 for patients seeking urology advice. We entered more than 400 German and English inputs and assessed the possible diagnoses suggested by this artificial intelligence tool. ChatGPT-3.5 scored well in providing a complete list of possible diagnoses and recommending a course of action mostly in line with current guidelines. The quality of the information was good overall, but missing and unclear sources for the information can be a problem.</div></div>","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"70 ","pages":"Pages 148-153"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142571737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P050 Real-world risk of death from cardiovascular disease, prostate cancer, and other causes in patients treated with radical prostatectomy or definitive radiation therapy for high-risk prostate cancer","authors":"Kvåle R.,&nbsp;Myklebust T.Å.","doi":"10.1016/S2666-1683(24)01178-9","DOIUrl":"10.1016/S2666-1683(24)01178-9","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"69 ","pages":"Pages 61-62"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142650732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P027 TRACER-study: The diagnostic accuracy of 18F-Prostate Specific Membrane Antigen (PSMA)-1007 PET/CT and 18F-Fluciclovine PET/CT for local staging in primary prostate cancer","authors":"Peeters L.,&nbsp;Hoekstra R.J.,&nbsp;Van Basten J-P.A.,&nbsp;Beulens A.,&nbsp;Roef M.,&nbsp;Brouwer C.,&nbsp;Nederend J.,&nbsp;Küsters - Van De Velde H.,&nbsp;Baas D.,&nbsp;Beerlage H.,&nbsp;Somford R.,&nbsp;Sedelaar M.,&nbsp;Vrijhof E.","doi":"10.1016/S2666-1683(24)01155-8","DOIUrl":"10.1016/S2666-1683(24)01155-8","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"69 ","pages":"Pages 29-30"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P002 Multi-omics investigation of the association and underlying mechanisms between antihypertensive drugs and urologic tumors: A Mendelian randomization study","authors":"Yang F.,&nbsp;Wang K.,&nbsp;Zhang X.,&nbsp;Liu T.","doi":"10.1016/S2666-1683(24)01133-9","DOIUrl":"10.1016/S2666-1683(24)01133-9","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"69 ","pages":"Page 2"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P018 Prostate cancer radiogenomics analysis reveals links between mpMRI and transcriptomics features in aggressive prostate cancer","authors":"Dinis Fernandes C.,&nbsp;Schaap A.,&nbsp;Kant J.,&nbsp;Van Houdt P.,&nbsp;Wijkstra H.,&nbsp;Bekers E.,&nbsp;Linder S.,&nbsp;Bergman A.M.,&nbsp;Van Der Heide U.,&nbsp;Massimo M.,&nbsp;Zwart W.,&nbsp;Eduati F.,&nbsp;Turco S.","doi":"10.1016/S2666-1683(24)01146-7","DOIUrl":"10.1016/S2666-1683(24)01146-7","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"69 ","pages":"Page 18"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P024 The added Value of PSMA PET/CT to MRI for local staging in prostate cancer patients undergoing radical prostatectomy","authors":"Soeterik T.,&nbsp;Heetman J.G.,&nbsp;Hermsen R.,&nbsp;Wever L.,&nbsp;Lavalaye J.,&nbsp;Vinken M.,&nbsp;Bahler C.D.,&nbsp;Yong C.,&nbsp;Tann M.,&nbsp;Kesch C.,&nbsp;Seifert R.,&nbsp;Telli T.,&nbsp;Chiu P.K.F.,&nbsp;Wu K.K.,&nbsp;Zattoni F.,&nbsp;Evangelista L.,&nbsp;Bettella S.,&nbsp;Ceci F.,&nbsp;Barone A.,&nbsp;Miszczyk M.,&nbsp;Gandaglia G.","doi":"10.1016/S2666-1683(24)01152-2","DOIUrl":"10.1016/S2666-1683(24)01152-2","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"69 ","pages":"Pages 24-25"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P042 Omission of contralateral systematic biopsies in unilateral suspicious prostate cancer on magnetic resonance imaging: Implications for radiotherapeutical treatment planning","authors":"van den Kroonenberg D.L.,&nbsp;Jonker S.,&nbsp;Jager A.,&nbsp;Stoter J.D.,&nbsp;Schaake E.,&nbsp;Hinnen K.A.,&nbsp;Van Der Voort Van Zyp J.R.N.,&nbsp;Eppinga W.S.C.,&nbsp;Schoots I.G.,&nbsp;Vis A.N.","doi":"10.1016/S2666-1683(24)01170-4","DOIUrl":"10.1016/S2666-1683(24)01170-4","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"69 ","pages":"Pages 51-52"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P090 Ten year results of a phase i trial of oncolytic adenovirus-mediated sodium Iodide Symporter (nis) gene delivery in locally recurrent prostate cancer following primary radiotherapy","authors":"Shah S.N.,&nbsp;Morris J.C.,&nbsp;Wiseman G.A.,&nbsp;Federspiel M.J.,&nbsp;Galanis E.,&nbsp;Russell S.J.,&nbsp;Wilson T.M.,&nbsp;Mynderse L.A.,&nbsp;Davis B.","doi":"10.1016/S2666-1683(24)01218-7","DOIUrl":"10.1016/S2666-1683(24)01218-7","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"69 ","pages":"Page 110"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}