Romanian Journal of Orthopaedic Surgery and Traumatology最新文献

Radical hysterectomy for locally advanced cervical cancer with Para-Aortic lymphadenectomy: case presentation 局部晚期宫颈癌根治性子宫切除术合并腹主动脉旁淋巴结切除术:病例报告

Romanian Journal of Orthopaedic Surgery and Traumatology Pub Date : 2022-06-01 DOI: 10.2478/rojost-2022-0003

R. Tulin, I. Slavu, C. Oprescu, A. Oprescu, D. P. Venter, C. Nitipir, A. Tulin

引用次数: 0

Bone and soft tissue pathology, the importance of the systematic approach 骨与软组织病理学，系统方法的重要性

Romanian Journal of Orthopaedic Surgery and Traumatology Pub Date : 2022-06-01 DOI: 10.2478/rojost-2022-0001

C. Cirstoiu

引用次数: 0

How to choose the bone modifying treatment for early stage and locally advanced breast cancer? 早期和局部晚期乳腺癌如何选择骨修饰治疗?

Romanian Journal of Orthopaedic Surgery and Traumatology Pub Date : 2022-06-01 DOI: 10.2478/rojost-2022-0005

Irina Alexandra Răduţ, R. Stoica, A. Paroșanu, I. Slavu, R. Tulin, Cristina Orlov-Slavu, A. Oprescu, Ioana Crețu, B. Crețu, Niţipir Cornelia

{"title":"How to choose the bone modifying treatment for early stage and locally advanced breast cancer?","authors":"Irina Alexandra Răduţ, R. Stoica, A. Paroșanu, I. Slavu, R. Tulin, Cristina Orlov-Slavu, A. Oprescu, Ioana Crețu, B. Crețu, Niţipir Cornelia","doi":"10.2478/rojost-2022-0005","DOIUrl":"https://doi.org/10.2478/rojost-2022-0005","url":null,"abstract":"Abstract Introduction: Breast cancer continues to be the most frequent malignancy in women worldwide. Considerable advances in oncology over the years have led to decreased mortality in early stage (EBC) and locally advanced (ABC) breast cancer, but this has raised concerns about possible long-term effects of anticancer treatment nonetheless. Purpose: The present paper aims to describe the efficacy and safety of osteoclast inhibitors, both as antiresorptive agents, reducing osteoporosis and fracture risk, and as adjuvant anticancer agents, potentially improving disease-related outcomes in patients with early stage and locally advanced breast cancer. Materials and methods: In this article, literature sources were selected and evaluated using the PRISMA 2020 guideline. Conclusions: Bisphosphonates are recommended for early stage and advanced breast cancer patients, either premenopausal or postmenopausal, with osteoporosis. Denosumab may also be used for postmenopausal women. Bisphosphonates also showed a statistically significant benefit for overall survival in postmenopausal women only. However, denosumab is not presently used for indications other than prevention or treatment of osteoporosis.","PeriodicalId":122325,"journal":{"name":"Romanian Journal of Orthopaedic Surgery and Traumatology","volume":"260 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125873285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Myositis ossificans in a 29 years old athletic female 一例29岁运动女性骨化性肌炎

Romanian Journal of Orthopaedic Surgery and Traumatology Pub Date : 2022-06-01 DOI: 10.2478/rojost-2022-0002

Mihai Mehedințu, Horia Toader, B. Serban, C. Cirstoiu

{"title":"Myositis ossificans in a 29 years old athletic female","authors":"Mihai Mehedințu, Horia Toader, B. Serban, C. Cirstoiu","doi":"10.2478/rojost-2022-0002","DOIUrl":"https://doi.org/10.2478/rojost-2022-0002","url":null,"abstract":"Abstract Myositis ossificans (MO) is a rare group of diseases in which heterotopic ossification occurs in muscles, tendons, nerves, or even subcutaneous fat. MO can occur in patients of all ages, but usually appears in young adults who practice sports or have a history of mechanical trauma, burns, infections or drug abuse. The article highlights the case of a 29-year-old athletic female who noticed, by random palpation, a small lump in her left biceps, near the radial insertion. The lump was not painful and noticeable with the naked eye. Rest and NSAIDs were recommended and all went well for about 3 months. However, after almost a week from that moment, the pain was excruciating, inflammation extend on the arm and forearm, she could not extend her arm anymore and its circumference was 30 cm from 24 initially. A biopsy was performed and the result was calcified fibrous tissue with suggestive aspect of myositis ossificans. Surgery was planned with reconstruction of the biceps tendon in mind. After surgery, the elbow was splinted at 90 degrees for two weeks, then dynamic splinting was performed with increasingly wider range of motion until full recovery was achieved. MO is a rare disease that involves many differential diagnoses, some of which are deadly and each with its own particularities, different imaging aspects and different treatments.","PeriodicalId":122325,"journal":{"name":"Romanian Journal of Orthopaedic Surgery and Traumatology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129380754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gene expression and molecular aspects in osteoarthritis of the knee - review of literature 膝关节骨关节炎的基因表达和分子研究——文献综述

Romanian Journal of Orthopaedic Surgery and Traumatology Pub Date : 2022-06-01 DOI: 10.2478/rojost-2022-0007

Sergiu-Andrei Iordache, B. Crețu, B. Serban, A. Cursaru, M. Popa, C. Cirstoiu

引用次数: 0

Breast cancer and musculoskeletal implications - potential mechanism of dissemination 乳腺癌和肌肉骨骼的影响-潜在的传播机制

Romanian Journal of Orthopaedic Surgery and Traumatology Pub Date : 2022-06-01 DOI: 10.2478/rojost-2022-0004

C. Șerboiu, D. Secară, B. Crețu, A. Dumitru, G. Pariza, C. Mavrodin, A. Baros, F. Păuleț, Alina Potorac, M. Cirstoiu

引用次数: 0

The use of osteoclast inhibitors in metastatic breast cancer 破骨细胞抑制剂在转移性乳腺癌中的应用

Romanian Journal of Orthopaedic Surgery and Traumatology Pub Date : 2022-06-01 DOI: 10.2478/rojost-2022-0006

C. Nitipir, Irina Alexandra Răduţ, A. Paroșanu, I. Slavu, Maria Cristina Orlov-Slavu, R. Tulin, A. Oprescu-Macovei, Ioana Crețu, B. Crețu, R. Stoica

{"title":"The use of osteoclast inhibitors in metastatic breast cancer","authors":"C. Nitipir, Irina Alexandra Răduţ, A. Paroșanu, I. Slavu, Maria Cristina Orlov-Slavu, R. Tulin, A. Oprescu-Macovei, Ioana Crețu, B. Crețu, R. Stoica","doi":"10.2478/rojost-2022-0006","DOIUrl":"https://doi.org/10.2478/rojost-2022-0006","url":null,"abstract":"Abstract Introduction: In most patients, metastatic breast cancer (MBC) is incurable. Consequently, the goal in this setting is life prolongation and quality of life improvement, although possible long-term effects of anticancer treatment need to be considered. Bone is the most common site of metastasis in breast cancer and its complex management includes minimizing the risk of skeletal-related events (SRE), maximizing pain control, stabilizing or even restoring function, preventing spinal cord compression, hypercalcemia of malignancy and fractures and reducing the need for radiotherapy and orthopedic surgery. Aim: The present paper aims to compare the efficacy and safety of zoledronic acid (and other bisphosphonates) with denosumab in the management of bone metastases in breast cancer patients. Materials and methods: In this article, required information was collected through literature review and keyword query using the PRISMA 2020 guideline. Conclusions: In the metastatic setting, it appears that denosumab is indeed superior to zoledronic acid in delaying and preventing skeletal related events, except for spinal cord compression and risk of surgery, and equally efficient in treatment of already present bone pain and hypercalcemia of malignancy, with similar adverse effects, overall survival and disease progression.","PeriodicalId":122325,"journal":{"name":"Romanian Journal of Orthopaedic Surgery and Traumatology","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131181605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Muscle-skeletal metastatic pattern in vulvar cancer 外阴癌的肌肉-骨骼转移模式

Romanian Journal of Orthopaedic Surgery and Traumatology Pub Date : 2021-12-01 DOI: 10.2478/rojost-2021-0014

D. Secară, Daniela C. Meca, S. Vasilescu, A. Uzunov, A. Baros, G. Pariza, Mădălina Iordache, M. Sajin, A. Dumitru, B. Crețu, C. Cirstoiu, N. Turcan, M. Cirstoiu

{"title":"Muscle-skeletal metastatic pattern in vulvar cancer","authors":"D. Secară, Daniela C. Meca, S. Vasilescu, A. Uzunov, A. Baros, G. Pariza, Mădălina Iordache, M. Sajin, A. Dumitru, B. Crețu, C. Cirstoiu, N. Turcan, M. Cirstoiu","doi":"10.2478/rojost-2021-0014","DOIUrl":"https://doi.org/10.2478/rojost-2021-0014","url":null,"abstract":"Abstract Vulvar cancer is a rare malignancy of the genital tract, the fourth most common type in this category. The most common form of the clinical appearance is long-lasting pruritus, a lump or mass on the vulva. Despite its histological type, in most cases, invasive vulvar cancer metastasizes primarily through the lymphatic system. Bone metastases related to gynecological cancers are rare, often underdiagnosed, and have a very poor prognosis. The most common site of metastasis in vulvar cancer is the lung, which is affected in about 45%, followed closely by the liver and brain. Bone metastases are present in about 10% to a quarter of cases. The most common places are the spine, pelvic bone, ribs, skull, limb bones and sternum. The only characteristic of the bone microenvironment is its high sensitivity to endocrine status, as vulvar cancer affects postmenopausal women. Thus, the theory of the protective role of estrogen on bone density and bone metastases remains an open door for future protection and treatment strategies.","PeriodicalId":122325,"journal":{"name":"Romanian Journal of Orthopaedic Surgery and Traumatology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123618924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medical rehabilitation of a patient with CRPS type I after tibial plateau fracture and sprain of the ankle: A case report and Literature review 1例I型CRPS患者胫骨平台骨折踝关节扭伤后的医学康复:1例报告并文献复习

Romanian Journal of Orthopaedic Surgery and Traumatology Pub Date : 2021-12-01 DOI: 10.2478/rojost-2021-0011

Claudia-Gabriela Potcovaru, T. Salmen, Alexandra Zarzu, P. Filip, C. Pop, D. Cinteză

{"title":"Medical rehabilitation of a patient with CRPS type I after tibial plateau fracture and sprain of the ankle: A case report and Literature review","authors":"Claudia-Gabriela Potcovaru, T. Salmen, Alexandra Zarzu, P. Filip, C. Pop, D. Cinteză","doi":"10.2478/rojost-2021-0011","DOIUrl":"https://doi.org/10.2478/rojost-2021-0011","url":null,"abstract":"Abstract Complex regional pain syndrome is a clinical syndrome characterized by chronic, severe, neuropathic pain, which is associated with sensory, trophic, and autonomic disorders and decreased range of motion of the affected joint. Symptoms begin at a variable interval, at least 6 weeks after a traumatic event or after surgery. The evolution of symptoms is unpredictable, as they can range from complete and self-limiting resolution to significant chronic pain with decreasing limb function and quality of life. Depending on the absence or presence of a well-identified neural lesion, types I and II of CRPS can be observed. Because it is a relatively rare condition, it can be overlooked due to the limited experience that doctors have with this one. A 61-year-old male patient presented with severe pain 9/10 on the Visual Analogue Scale (VAS) and a significant decrease in mobility after suffering a traumatic fracture with a left tibial plateau fracture 4 months before, which required orthopedic treatment with a plate and screws, and a left ankle sprain. Previously, the patient presented to several emergency services where he received anti-inflammatory and analgesic treatment with gradual aggravation of pain and impaired mobility of the left lower limb, walking being possible only on two axillary crutches. The patient received treatment that combined drug therapy with medical rehabilitation exercises and physical therapy agents, with a favorable evolution. At the time of discharge, the pain was 5/10 on the VAS scale and the patient could move with a single Canadian crutch.","PeriodicalId":122325,"journal":{"name":"Romanian Journal of Orthopaedic Surgery and Traumatology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126129222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perioperative pain management in total hip and knee arthroplasty 全髋关节置换术围手术期疼痛处理

Romanian Journal of Orthopaedic Surgery and Traumatology Pub Date : 2021-12-01 DOI: 10.2478/rojost-2021-0009

C. Cirstoiu

引用次数: 0