发布求助
文献互助 智能选刊 最新文献

Expert Review of Anti-infective Therapy最新文献

筛选
英文 中文
The clinical outcomes and effectiveness of antiviral agents among underweight patients with COVID-19. 体重不足的 COVID-19 患者的临床结果和抗病毒药物的有效性。
IF 5.7 2区 医学
Expert Review of Anti-infective Therapy Pub Date : 2024-05-01 Epub Date: 2024-01-08 DOI: 10.1080/14787210.2024.2303017
Jheng-Yan Wu, Mei-Yuan Liu, Mei-Chuan Lee, Kuo-Chuan Hung, Wan-Hsuan Hsu, Ya-Wen Tsai, Ting-Hui Liu, Po-Yu Huang, Min-Hsiang Chuang, Shu-Ching Tseng, Chih-Ying Lu, Chih-Cheng Lai
{"title":"The clinical outcomes and effectiveness of antiviral agents among underweight patients with COVID-19.","authors":"Jheng-Yan Wu, Mei-Yuan Liu, Mei-Chuan Lee, Kuo-Chuan Hung, Wan-Hsuan Hsu, Ya-Wen Tsai, Ting-Hui Liu, Po-Yu Huang, Min-Hsiang Chuang, Shu-Ching Tseng, Chih-Ying Lu, Chih-Cheng Lai","doi":"10.1080/14787210.2024.2303017","DOIUrl":"10.1080/14787210.2024.2303017","url":null,"abstract":"<p><strong>Objectives: </strong>This study investigated the outcomes of underweight patients with COVID-19 and the effectiveness of antiviral agents in this population.</p><p><strong>Methods: </strong>A retrospective cohort study using theTriNetX research network was conducted. Propensity score matching (PSM) was employed to balance the first cohort involving COVID-19 patients with underweight and normal-weight. In the second cohort, underweight patients receiving antiviral agents and untreated individuals were matched using PSM. The primary outcome was a composite of all-cause hospitalization and death during the 7-30-day follow-up period.</p><p><strong>Results: </strong>After PSM, the first cohort including each group of 13,502 patients with balanced baseline characteristics were identified for comparing the outcome of patients with underweight and normal weight. The underweight group had a higher risk of the composite primary outcome than those with normal weight (hazard ratio [HR], 1.251; 95% confidence interval [CI], 1.132-1.382). The second cohort included each 884 underweight patients with and without receiving antivirals.Compared with untreated patients, those receiving antiviral treatment had a lower risk of composite primary outcomes (HR, 0.426; 95% CI, 0.278-0.653).</p><p><strong>Conclusion: </strong>Underweight status may be associated with a higher risk of all-cause hospitalization and death in patients with COVID-19.Among underweight patients, antiviral agents demonstrated clinically beneficial effects.</p>","PeriodicalId":12213,"journal":{"name":"Expert Review of Anti-infective Therapy","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139097679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A multifaceted strategy is needed to limit the over-the-counter sale of antimicrobials. 需要采取多方面的战略来限制抗菌药的非处方销售。
IF 4.2 2区 医学
Expert Review of Anti-infective Therapy Pub Date : 2024-05-01 Epub Date: 2024-03-11 DOI: 10.1080/14787210.2024.2322450
Carl Llor, Ana Moragas
{"title":"A multifaceted strategy is needed to limit the over-the-counter sale of antimicrobials.","authors":"Carl Llor, Ana Moragas","doi":"10.1080/14787210.2024.2322450","DOIUrl":"10.1080/14787210.2024.2322450","url":null,"abstract":"","PeriodicalId":12213,"journal":{"name":"Expert Review of Anti-infective Therapy","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139912438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biosimilars as antivirals: opportunities and challenges. 作为抗病毒药物的生物仿制药：机遇与挑战。
IF 5.7 2区 医学
Expert Review of Anti-infective Therapy Pub Date : 2024-05-01 Epub Date: 2024-02-01 DOI: 10.1080/14787210.2024.2313064
Anan S Jarab, Shrouq R Abu Heshmeh, Ahmad Z Al Meslamani
{"title":"Biosimilars as antivirals: opportunities and challenges.","authors":"Anan S Jarab, Shrouq R Abu Heshmeh, Ahmad Z Al Meslamani","doi":"10.1080/14787210.2024.2313064","DOIUrl":"10.1080/14787210.2024.2313064","url":null,"abstract":"","PeriodicalId":12213,"journal":{"name":"Expert Review of Anti-infective Therapy","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of vaginitis caused by non-albicans Candida species. 治疗由非阿氏念珠菌引起的阴道炎。
IF 5.7 2区 医学
Expert Review of Anti-infective Therapy Pub Date : 2024-05-01 Epub Date: 2024-05-16 DOI: 10.1080/14787210.2024.2347953
Jack D Sobel
{"title":"Treatment of vaginitis caused by non-albicans Candida species.","authors":"Jack D Sobel","doi":"10.1080/14787210.2024.2347953","DOIUrl":"10.1080/14787210.2024.2347953","url":null,"abstract":"<p><strong>Introduction: </strong>In the face of increased frequency of non-albicans Candida vulvovaginitis (VVC) reported worldwide, there is a paucity of effective oral and topical antifungal drugs available. Drug selection is further handicapped by an absence of data of clinical efficacy of available antifungal drugs for these infections.</p><p><strong>Areas covered: </strong>In this review, attention is directed at the cause of drug shortage as well as increased frequency of non-albicans Candida (NAC) vulvovaginitis. There is widespread recognition of reduced in vitro azole drug susceptibility in NAC species. Moreover, antifungal susceptibility tests have not been standardized or validated for NAC isolates, hence clinicians rely on an element of empiricism especially given the absence of randomized controlled comparative studies targeting NAC species. Clinical spectrum of NAC species isolates is highly variable with ongoing difficulty in determining a causal role in symptomatic patients.</p><p><strong>Expert opinion: </strong>We have entered the era of demand for Candida species-specific therapy and although consensus treatment guidelines are emerging, new antifungal agents that target these multiple-azole resistant or relatively resistant vaginal NAC species are urgently needed.</p>","PeriodicalId":12213,"journal":{"name":"Expert Review of Anti-infective Therapy","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors and patterns of empirical antibiotic therapy and associated outcomes in COVID-19 patients: a retrospective study in a tertiary care facility in South India. COVID-19 患者经验性抗生素治疗的预测因素和模式及相关结果：印度南部一家三级医疗机构的回顾性研究。
IF 5.7 2区 医学
Expert Review of Anti-infective Therapy Pub Date : 2024-05-01 Epub Date: 2024-01-18 DOI: 10.1080/14787210.2024.2303019
Lipin Lukose, Gursimran Kaur, Mohammed Asif M, Gail Ann Abraham, Kanav Khera, Viswam K Subeesh, Ronald L Castelino, Shubhada Karanth, Chandrashekar Udyavara Kudru, Muralidhar Varma, Sonal Sekhar Miraj
{"title":"Predictors and patterns of empirical antibiotic therapy and associated outcomes in COVID-19 patients: a retrospective study in a tertiary care facility in South India.","authors":"Lipin Lukose, Gursimran Kaur, Mohammed Asif M, Gail Ann Abraham, Kanav Khera, Viswam K Subeesh, Ronald L Castelino, Shubhada Karanth, Chandrashekar Udyavara Kudru, Muralidhar Varma, Sonal Sekhar Miraj","doi":"10.1080/14787210.2024.2303019","DOIUrl":"10.1080/14787210.2024.2303019","url":null,"abstract":"<p><strong>Background: </strong>The coronavirus disease (COVID-19) led to a global health crisis. Inappropriate use of antibiotics in COVID-19 patients has been a concern, leading to antimicrobial resistance. This study evaluated the patterns and predictors of empirical antibiotic therapy in COVID-19 patients and associated outcomes.</p><p><strong>Methods: </strong>A hospital-based retrospective study was conducted with 525 patients admitted to Kasturba Hospital, Manipal, India, with moderate and severe COVID-19 from 1 March to 1 August 2021. They were divided based on empirical therapy, and predictors of antibiotic usage were assessed by logistic regression.</p><p><strong>Results: </strong>Four hundred and eighty (91.4%) COVID-19 patients received at least one course of antibiotics, with 440 (83.8%) initiating empirical therapy. Patients with severe COVID-19 manifestations were more likely to be prescribed empirical antibiotics. Multivariable analysis showed that patients initiated on empirical antibiotics had significantly elevated levels of procalcitonin [OR: 3.91 (95% CI: 1.66-9.16) (<i>p</i> = 0.001)], invasive ventilation [OR: 3.93 (95% CI: 1.70-9.09) (<i>p</i> = 0.001)], shortness of breath [OR: 2.25 (95% CI: 1.30-3.89) (<i>p</i> = 0.003)] and higher CRP levels [OR: 1.01 (95% CI: 1.00-1.01) (<i>p</i> = 0.005)]. Most antibiotics (65.9%) were prescribed from the 'Watch' group, the highest being ceftriaxone. Only 23.8% of the patients had microbiologically confirmed infections.</p><p><strong>Conclusion: </strong>The study identified predictors for initiating empirical antibacterial therapy in our setting.</p>","PeriodicalId":12213,"journal":{"name":"Expert Review of Anti-infective Therapy","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139377354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How do we change our approach to COVID with the changing face of disease? 面对不断变化的疾病，我们如何改变 COVID 的方法？
IF 5.7 2区 医学
Expert Review of Anti-infective Therapy Pub Date : 2024-04-20 DOI: 10.1080/14787210.2024.2345881
Vasso Apostolopoulos, Jack Feehan, Vivek P. Chavda
{"title":"How do we change our approach to COVID with the changing face of disease?","authors":"Vasso Apostolopoulos, Jack Feehan, Vivek P. Chavda","doi":"10.1080/14787210.2024.2345881","DOIUrl":"https://doi.org/10.1080/14787210.2024.2345881","url":null,"abstract":"The emergence of SARS-CoV-2 triggered a global health emergency, causing > 7 million deaths thus far. Limited early knowledge spurred swift research, treatment, and vaccine developments. Implementa...","PeriodicalId":12213,"journal":{"name":"Expert Review of Anti-infective Therapy","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140628333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surveillance and prevention of healthcare-associated infections: best practices to prevent ventilator-associated events 医疗保健相关感染的监测和预防：预防呼吸机相关事件的最佳实践
IF 5.7 2区 医学
Expert Review of Anti-infective Therapy Pub Date : 2024-04-20 DOI: 10.1080/14787210.2024.2345877
Leonardo Lorente, Joan Sabater-Riera, Jordi Rello
{"title":"Surveillance and prevention of healthcare-associated infections: best practices to prevent ventilator-associated events","authors":"Leonardo Lorente, Joan Sabater-Riera, Jordi Rello","doi":"10.1080/14787210.2024.2345877","DOIUrl":"https://doi.org/10.1080/14787210.2024.2345877","url":null,"abstract":"Ventilator associated pneumonia (VAP) leads to an increase in morbidity, mortality and healthcare costs. In addition to increased evidence from the latest European and American guidelines (publishe...","PeriodicalId":12213,"journal":{"name":"Expert Review of Anti-infective Therapy","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140628460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding the influence of the microbiome on childhood infections 了解微生物群对儿童感染的影响
IF 5.7 2区 医学
Expert Review of Anti-infective Therapy Pub Date : 2024-04-12 DOI: 10.1080/14787210.2024.2340664
Sarah M. Heston, Jillian H. Hurst, Matthew S. Kelly
{"title":"Understanding the influence of the microbiome on childhood infections","authors":"Sarah M. Heston, Jillian H. Hurst, Matthew S. Kelly","doi":"10.1080/14787210.2024.2340664","DOIUrl":"https://doi.org/10.1080/14787210.2024.2340664","url":null,"abstract":"The microbiome is known to have a substantial impact on human health and disease. However, the impacts of the microbiome on immune system development, susceptibility to infectious diseases, and vac...","PeriodicalId":12213,"journal":{"name":"Expert Review of Anti-infective Therapy","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140584034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to: ‘letter to the editor: “A multifaceted strategy is needed to limit the over-the-counter sale of antimicrobials “’ 回应：致编辑的信："限制非处方销售抗菌药需要多方面的策略"'
IF 5.7 2区 医学
Expert Review of Anti-infective Therapy Pub Date : 2024-04-05 DOI: 10.1080/14787210.2024.2337824
Eric Kofi Ngyedu, Joseph Elikem Efui Acolatse, George Akafity, Robert Incoom, Audu Rauf, R Andrew Seaton, Jacqueline Sneddon, Elaine Cameron, Margaret Watson, Marta Wanat, Brian Godman, Amanj Kurdi
{"title":"Response to: ‘letter to the editor: “A multifaceted strategy is needed to limit the over-the-counter sale of antimicrobials “’","authors":"Eric Kofi Ngyedu, Joseph Elikem Efui Acolatse, George Akafity, Robert Incoom, Audu Rauf, R Andrew Seaton, Jacqueline Sneddon, Elaine Cameron, Margaret Watson, Marta Wanat, Brian Godman, Amanj Kurdi","doi":"10.1080/14787210.2024.2337824","DOIUrl":"https://doi.org/10.1080/14787210.2024.2337824","url":null,"abstract":"Published in Expert Review of Anti-infective Therapy (Ahead of Print, 2024)","PeriodicalId":12213,"journal":{"name":"Expert Review of Anti-infective Therapy","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140584024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effectiveness of novel oral antiviral treatment for non-hospitalized high-risk patients with COVID-19 during predominance of omicron XBB subvariants 新型口服抗病毒治疗对奥米克隆 XBB 亚变体占优势期间非住院高危 COVID-19 患者的有效性
IF 5.7 2区 医学
Expert Review of Anti-infective Therapy Pub Date : 2024-04-03 DOI: 10.1080/14787210.2024.2339398
Chi-Kuei Hsu, Wan-Hsuan Hsu, Bo-Wen Shiau, Ya-Wen Tsai, Jheng-Yan Wu, Ting-Hui Liu, Po-Yu Huang, Min-Hsiang Chuang, Chih-Cheng Lai
{"title":"The effectiveness of novel oral antiviral treatment for non-hospitalized high-risk patients with COVID-19 during predominance of omicron XBB subvariants","authors":"Chi-Kuei Hsu, Wan-Hsuan Hsu, Bo-Wen Shiau, Ya-Wen Tsai, Jheng-Yan Wu, Ting-Hui Liu, Po-Yu Huang, Min-Hsiang Chuang, Chih-Cheng Lai","doi":"10.1080/14787210.2024.2339398","DOIUrl":"https://doi.org/10.1080/14787210.2024.2339398","url":null,"abstract":"This study investigated the association between nirmatrelvir plus ritonavir (NMV-r) or molnupiravir and the outcomes of non-hospitalized high-risk patients with COVID-19 during Omicron XBB subvaria...","PeriodicalId":12213,"journal":{"name":"Expert Review of Anti-infective Therapy","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140584401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信