MedPulse International Journal of Biochemistry最新文献_第3页

Relevance of Lipoprotein (a) in predicting the diagnosis of type II diabetes mellitus 脂蛋白(a)在预测II型糖尿病诊断中的相关性

MedPulse International Journal of Biochemistry Pub Date : 1900-01-01 DOI: 10.26611/1002916

Amrita, Amrendra Amar

引用次数: 1

Glucose levels in pleural fluids of effusive pleural diseases 积液性胸膜疾病胸膜液中的葡萄糖水平

MedPulse International Journal of Biochemistry Pub Date : 1900-01-01 DOI: 10.26611/10021114

Sneha S Narkar, S. Rane, D. S. Salgaonkar

引用次数: 0

Total cholesterol/high density lipoprotein-cholesterol ratio as an indicator of Dyslipidemia in hypothyroidism 总胆固醇/高密度脂蛋白-胆固醇比值作为甲减患者血脂异常的指标

MedPulse International Journal of Biochemistry Pub Date : 1900-01-01 DOI: 10.26611/10021921

N. Chandrika

{"title":"Total cholesterol/high density lipoprotein-cholesterol ratio as an indicator of Dyslipidemia in hypothyroidism","authors":"N. Chandrika","doi":"10.26611/10021921","DOIUrl":"https://doi.org/10.26611/10021921","url":null,"abstract":"Background: The thyroid hormones are involved in controlling metabolism, growth and functions of various organ systems of our body. Hypothyroidism, a very common endocrinopathy features reduced production of thyroid hormones. In hypothyroidism we encounter abnormal circulating lipid fractions which is termed as ‘Dyslipidemia’. The coexistence of dyslipidemia and hypothyroidism is associated with development of atherosclerosis. Aim: This research is undertaken to assess the potential of TC/HDL-C ratio to disclose dyslipidemia in hypothyroidism. Methodology: The study consists of two major groups, the ‘Cases’ comprising of Fifty hypothyroid patients and ‘Controls’, with fifty age and gender matched healthy adults. The Cases are further subdivided into Twenty ‘Known cases’ of Hypothyroid patients, already receiving treatment and thirty ‘New cases’. The ‘New cases’ sub group further is subdivided as Twenty-one ‘Overt hypothyroids’(OH) and nine ‘Subclinical Hypothyroids’ (SCH). The Biochemical parameters estimated in all subjects of the study includes, Serum TSH, T3, T4, Total Cholesterol (TC) and High density lipoprotein-cholesterol(HDL-C). TC/HDL ratio was then calculated . Result: The study shows a significant elevation (p = 0.05) in the TC/HDL-C ratio in hypothyroid patients (3.67 ± 1.02) when compared to healthy controls (3.29 ± 0.95). TC/HDL-C ratio is more elevated in OH (4.01 ± 1.28) than in SCH (3.46 ± 0.92). The levels in ‘New cases’ sub-group and OH sub sub group have significantly higher ratio than in healthy controls (p = 0.02 and p = 0.01 respectively). TC/HDL-C ratio value in “known cases’ group who are those hypothyroid patients on Levo-thyroxine therapy is (3.40 ± 0.61) less than those who are newly diagnosed. Conclusion: TC/HDL-C ratio is not only raised in hypothyroid patients but it is seen increasing with severity and prolonged duration of disease. The calculation of TC/HDL-C ratio should be routinely put into practice to detect hypothyroid patients with dyslipidemia.","PeriodicalId":121008,"journal":{"name":"MedPulse International Journal of Biochemistry","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115329263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation and characterization of melatonin conjugates as an immunogen 褪黑素缀合物作为免疫原的评价和表征

MedPulse International Journal of Biochemistry Pub Date : 1900-01-01 DOI: 10.26611/10022013

Lathika .

引用次数: 0

Interleukin-23, a novel marker in the diagnosis of psoriasis 白介素-23:诊断银屑病的新标志物

MedPulse International Journal of Biochemistry Pub Date : 1900-01-01 DOI: 10.26611/1002928

T. Rameswari, G. Ezhil

引用次数: 0

Association among vitamin d and HbA1c in type-2 diabetes mellitus patients in the north coastal Andhra Pradesh 安得拉邦北部沿海地区2型糖尿病患者维生素d与HbA1c的关系

MedPulse International Journal of Biochemistry Pub Date : 1900-01-01 DOI: 10.26611/10021121

Mandarapu Roopalath

引用次数: 0

Gender wise comparison of biochemical variables in normal individuals and Chronic kidney disease patients with Diabetes mellitus 正常人与慢性肾病合并糖尿病患者生化指标的性别比较

MedPulse International Journal of Biochemistry Pub Date : 1900-01-01 DOI: 10.26611/10021228

P. Mohanalakshmi, N. Muninathan

引用次数: 0

Compressive idea of manifestation and biochemical relation of acute pancreatitis in tertiary care hospital 三级医院急性胰腺炎临床表现及生化关系的压缩观念

MedPulse International Journal of Biochemistry Pub Date : 1900-01-01 DOI: 10.26611/10021932

S. Bharti

引用次数: 0

Assessment of serum nitric oxide level in cigarette smoking 吸烟时血清一氧化氮水平的评估

MedPulse International Journal of Biochemistry Pub Date : 1900-01-01 DOI: 10.26611/10021834

G. Sasirekha

{"title":"Assessment of serum nitric oxide level in cigarette smoking","authors":"G. Sasirekha","doi":"10.26611/10021834","DOIUrl":"https://doi.org/10.26611/10021834","url":null,"abstract":"Background: Cigarette smoke has been implicated as a major risk factor in various diseases associated with endothelial dysfunction like essential hypertension, atherosclerosis and related cardiovascular dysfunction. Nitric oxide, an important second messanger plays a pivotal role in maintaining vasomotor tone and its level is also found to be altered in many chronic vascular disorders. The particulates in cigarette smoke is presumed to affect the production NO in vascular endothelium. Hence, it is proposed to study the effect of cigarette smoking in influencing Nitric oxide level. The study sample comprised of 138 chronic smokers and144 apparently healthy nonsmokers . Plasma glucose, total cholesterol (TC), high density lipoprotein cholesterol (HDL-c) and triglyceride concentration (TGL) were determined enzymatically and serum NO index (NOx) estimated by Griess method. It was found that serum NOx level was not influenced by biochemical parameters like plasma glucose and lipid profile. The estimated mean NOx levels was slightly lower in smokers(15.92 with SD 5.4) than in nonsmokers (16.66with SD 6.73) . However the difference was not statistically significant ( P= 0.31). It is concluded that there is no significant correlation between serum nitric oxide level and smoking, based on this study.","PeriodicalId":121008,"journal":{"name":"MedPulse International Journal of Biochemistry","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130419805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of protein carbonyl in type II diabetes mellitus in a tertiary care hospital 某三级医院2型糖尿病患者蛋白羰基的评价

MedPulse International Journal of Biochemistry Pub Date : 1900-01-01 DOI: 10.26611/10021022

G. Kumar, S. Priya, Nagarjuna Sivaraj

引用次数: 0