Eye sciencePub Date : 2020-03-05DOI: 10.21037/AES-19-108
W. Stark, G. Goodman, D. Goodman, J. Gottsch
{"title":"Uveitis secondary to cancer therapeutics","authors":"W. Stark, G. Goodman, D. Goodman, J. Gottsch","doi":"10.21037/AES-19-108","DOIUrl":"https://doi.org/10.21037/AES-19-108","url":null,"abstract":"Because of the high incidence and great variety of complications associated with anterior chamber intraocular lenses, we have developed a technique for the implantation of a posterior chamber intraocular lens in the absence of posterior capsular support. The posterior chamber IOL is placed in the ciliary sulcus by suturing the superior haptic to the iris and the inferior haptic to the sclera at the ciliary sulcus. We have used this technique successfully in both complicated extracapsular surgery and secondary intraocular lens implantation.","PeriodicalId":12096,"journal":{"name":"Eye science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.21037/AES-19-108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68294650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eye sciencePub Date : 2016-04-19DOI: 10.21037/JES.2016.04.15
Jiakui Wang, Tzu-Lun Huang, P. Su, P. Chang
{"title":"Approved pharmacotherapy for myopic choroidal neovascularization: a review of randomized controlled trials in ranibizumab and aflibercept.","authors":"Jiakui Wang, Tzu-Lun Huang, P. Su, P. Chang","doi":"10.21037/JES.2016.04.15","DOIUrl":"https://doi.org/10.21037/JES.2016.04.15","url":null,"abstract":"Myopic choroidal neovascularization (mCNV) can cause severe visual impairment in highly myopic patients. We review the randomized trials of two approved pharmacotherapy for treating mCNV, including intravitreal injections of ranibizumab and aflibercept. These two vascular endothelial growth factor (VEGF) antagonists show superior ability to improve vision and reduce macular thickness, comparing with sham injections or verteporfin photodynamic therapy (vPDT). There is no severe ocular or systemic adverse reaction reported in studies associated with ranibizumab and aflibercept for mCNV. Prompt treatment with these agents can lead to a better outcome.","PeriodicalId":12096,"journal":{"name":"Eye science","volume":"42 1","pages":"198-200"},"PeriodicalIF":0.0,"publicationDate":"2016-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90753240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eye sciencePub Date : 2016-04-19DOI: 10.21037/JES.2016.04.16
Shao-Wei Weng, Tzu-Lun Huang, P. Su, P. Chang, Jiakui Wang
{"title":"Intravitreal aflibercept for rubeosis iridis secondary to proliferative diabetic retinopathy.","authors":"Shao-Wei Weng, Tzu-Lun Huang, P. Su, P. Chang, Jiakui Wang","doi":"10.21037/JES.2016.04.16","DOIUrl":"https://doi.org/10.21037/JES.2016.04.16","url":null,"abstract":"The purpose of this article is to report a case with rubeosis iridis treated by intravitreal aflibercept. A 61-year-old man had iris neovascularization and scanty vitreous hemorrhage secondary to proliferative diabetic retinopathy in the right eye. Neither neovascularization of angle nor elevation of intraocular pressure was found. Single intravitreal aflibercept 2 mg injection was performed. Rubeosis iridis disappeared on the next day. Scattered retinal laser photocoagulation was added 1 week later. There was no recurrence after 3-month follow-up. Aflibercept may serve as another anti-vascular endothelial growth factor (anti-VEGF) for treating rubeosis iridis.","PeriodicalId":12096,"journal":{"name":"Eye science","volume":"21 1","pages":"201-3"},"PeriodicalIF":0.0,"publicationDate":"2016-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80794753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of visual electrophysiology for the diagnosis and treatment of cataracts.","authors":"Duoru Lin, Jingjing Chen, Haotian Lin, Weirong Chen","doi":"10.21037/JES.2016.04.14","DOIUrl":"https://doi.org/10.21037/JES.2016.04.14","url":null,"abstract":"Visual electrophysiology is widely used in clinical ophthalmology. It is also of significant value in the objective assessment of visual function in adult and pediatric cataract patients and for the diagnosis of and research on retinal and visual pathway diseases. This article systematically reviews visual electrophysiology techniques, their applications in the diagnosis and treatment of adult and pediatric cataracts, and factors influencing the application of visual electrophysiology during surgical treatment for cataracts.","PeriodicalId":12096,"journal":{"name":"Eye science","volume":"105 1","pages":"190-7"},"PeriodicalIF":0.0,"publicationDate":"2016-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75911140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eye sciencePub Date : 2016-04-19DOI: 10.21037/JES.2016.04.17
Sailaja Bondalapati, A. Pathengay, J. Chhablani
{"title":"External drainage for exudative retinal detachment secondary to central serous chorioretinopathy.","authors":"Sailaja Bondalapati, A. Pathengay, J. Chhablani","doi":"10.21037/JES.2016.04.17","DOIUrl":"https://doi.org/10.21037/JES.2016.04.17","url":null,"abstract":"BACKGROUND\u0000To report the outcomes of external drainage of subretinal fluid (SRF) in exudative retinal detachment secondary to central serous chorioretinopathy (CSCR).\u0000\u0000\u0000METHODS\u0000Retrospective observational analysis of six eyes with exudative retinal detachment secondary to CSCR who underwent external drainage of SRF between 2004 and 2014 was performed. Collected data included demographics, steroid usage, surgical details, and visual acuity preoperatively and postoperative visual acuity and clinical examination data were collected.\u0000\u0000\u0000RESULTS\u0000Six eyes of six subjects were included with mean age of 45 years (range, 32 to 61 years). All subjects were male. Mean duration of symptoms was 4.6 months (range, 3 to 8 months). The pre-operative best-corrected visual acuity (BCVA) ranged from perception of light to 20/60. Four eyes were treated with conventional external drainage and two underwent Chandelier-assisted external drainage. Three cases had laser treatment before drainage and one case underwent photodynamic therapy (PDT) after drainage. The BCVA at last follow-up ranged from 20/2,000 (counting fingers at 2 feet) to 20/20. No recurrences were noted in any of the cases till the last follow-up. Mean duration of follow-up was 38 months.\u0000\u0000\u0000CONCLUSIONS\u0000Our study demonstrates successful management of exudative retinal detachment secondary to CSCR with external SRF drainage without any complications.","PeriodicalId":12096,"journal":{"name":"Eye science","volume":"59 1","pages":"204-8"},"PeriodicalIF":0.0,"publicationDate":"2016-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90939771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eye sciencePub Date : 2016-04-18DOI: 10.21037/JES.2016.04.10
Zhenggen Wu, Chukai Huang, C. Zheng, Yuqiang Huang, Wanqi Zhang, Di Ma
{"title":"The safety and efficacy of modified minimally invasive trabeculectomy for the treatment of primary chronic angle-closure glaucoma.","authors":"Zhenggen Wu, Chukai Huang, C. Zheng, Yuqiang Huang, Wanqi Zhang, Di Ma","doi":"10.21037/JES.2016.04.10","DOIUrl":"https://doi.org/10.21037/JES.2016.04.10","url":null,"abstract":"BACKGROUND\u0000Primary chronic angle-closure glaucoma (PCACG) is one of the main types of glaucoma in China. Trabeculectomy is the most commonly used glaucoma filtration surgery for glaucoma in the world. Conventional trabeculectomy is prone to anesthesia-related complications intraoperative and operation-related complications postoperative in PCACG treatment. Modified minimally invasive trabeculectomy maybe can reduce the incidence of complications.\u0000\u0000\u0000METHODS\u0000We conducted a prospective case series study and performed modified fornix-based trabeculectomy in 27 patients (30 eyes) under topical anesthesia; we then observed intraoperative anesthesia and cooperation effect, intraoperative and postoperative complications, preoperative and postoperative visual acuity, intraocular pressure (IOP), visual field, and the use of ocular hypotensive drugs. The patients were followed up for at least 12 months.\u0000\u0000\u0000RESULTS\u0000All operations were completed successfully with no intraoperative complications. All 27 patients (30 eyes) were followed up for at least 12 months. No significant decrease in visual acuity was observed at days 1 or 7 and at months 1, 3, 6, and 12 after operation; however, a significant decrease in IOP was observed at days 1 and 7 and at months 1, 3, 6, and 12 after operation. Moreover, no significant progression in visual field mean defect was observed at month 12 after operation, and the number of ocular hypotensive drugs required was significantly reduced at months 6 and 12 after operation. By month 12 after operation, the overall success rate was 93.33% (28/30).\u0000\u0000\u0000CONCLUSIONS\u0000Modified minimally invasive trabeculectomy is safe and effective for the treatment of PCACG.","PeriodicalId":12096,"journal":{"name":"Eye science","volume":"2 1","pages":"160-6"},"PeriodicalIF":0.0,"publicationDate":"2016-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81481886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eye sciencePub Date : 2016-04-18DOI: 10.21037/JES.2016.04.07
Preeti Patil-Chhablani, S. Murthy, M. Swaminathan
{"title":"Ophthalmic profile and systemic features of pediatric facial nerve palsy.","authors":"Preeti Patil-Chhablani, S. Murthy, M. Swaminathan","doi":"10.21037/JES.2016.04.07","DOIUrl":"https://doi.org/10.21037/JES.2016.04.07","url":null,"abstract":"BACKGROUND\u0000Facial nerve palsy (FNP) occurs less frequently in children as compared to adults but most cases are secondary to an identifiable cause. These children may have a variety of ocular and systemic features associated with the palsy and need detailed ophthalmic and systemic evaluation.\u0000\u0000\u0000METHODS\u0000This was a retrospective chart review of all the cases of FNP below the age of 16 years, presenting to a tertiary ophthalmic hospital over the period of 9 years, from January 2000 to December 2008.\u0000\u0000\u0000RESULTS\u0000A total of 22 patients were included in the study. The average age at presentation was 6.08 years (range, 4 months to 16 years). Only one patient (4.54%) had bilateral FNP and 21 cases (95.45%) had unilateral FNP. Seventeen patients (77.27%) had congenital palsy and of these, five patients had a syndromic association, three had birth trauma and nine patients had idiopathic palsy. Five patients (22.72%) had an acquired palsy, of these, two had a traumatic cause and one patient each had neoplastic origin of the palsy, iatrogenic palsy after surgery for hemangioma and idiopathic palsy. Three patients had ipsilateral sixth nerve palsy, two children were diagnosed to have Moebius syndrome, one child had an ipsilateral Duane's syndrome with ipsilateral hearing loss. Corneal involvement was seen in eight patients (36.36%). Amblyopia was seen in ten patients (45.45%). Neuroimaging studies showed evidence of trauma, posterior fossa cysts, pontine gliosis and neoplasms such as a chloroma. Systemic associations included hemifacial macrosomia, oculovertebral malformations, Dandy Walker syndrome, Moebius syndrome and cerebral palsy\u0000\u0000\u0000CONCLUSIONS\u0000FNP in children can have a number of underlying causes, some of which may be life threatening. It can also result in serious ocular complications including corneal perforation and severe amblyopia. These children require a multifaceted approach to their care.","PeriodicalId":12096,"journal":{"name":"Eye science","volume":"3 1","pages":"147-50"},"PeriodicalIF":0.0,"publicationDate":"2016-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89211822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eye sciencePub Date : 2016-04-18DOI: 10.21037/JES.2016.04.08
Hongjie Yu, Y. Shao, H. Yuan, Bo Yan
{"title":"Age-determined referral criteria of myopia for large-scale vision screening.","authors":"Hongjie Yu, Y. Shao, H. Yuan, Bo Yan","doi":"10.21037/JES.2016.04.08","DOIUrl":"https://doi.org/10.21037/JES.2016.04.08","url":null,"abstract":"BACKGROUND\u0000This study aimed to explore the best screening measure of myopia and its associated optimal referral criteria for children aged between 6 and 16.\u0000\u0000\u0000METHODS\u0000After informed consent of cycloplegia was obtained, a total of 6,321 children aged between 6 and 16 from 53 primary or junior middle schools in Jiading District of Shanghai were included in our population-based study. Receiver operating characteristic (ROC) curve was performed to determine the best cutoff points, sensitivities and specificities of different screening tests, including uncorrected visual acuity (UCVA), noncycloplegic autorefraction (NCAR) and the combination of these two tests.\u0000\u0000\u0000RESULTS\u0000There was significant difference in prevalence of myopia between boys and girls (χ2 = 6.358, P = 0.012). Compared with children of low age, the prevalence of older children was significantly higher (χ2 = 1,386.404, P < 0.001). For the combination of UCVA and NCAR, the best cutoff point was UCVA less than or equal to 0.2 logarithm of minimum angle of resolution (MAR) (20/30) and NCAR spherical equivalent refraction (SER) less than or equal to -0.75 diopters (D), with associated sensitivity and specificity of 75.0% and 85.0%, respectively, which were higher than those of UCVA and NCAR alone. After stratified by age, the best cutoff points were varied among children. The accuracy for children aged between 9 and 12 was higher than that for other ages.\u0000\u0000\u0000CONCLUSIONS\u0000The best screening measure of myopia was the combination of UCVA and NCAR. The optimal referral criteria of myopia for children should be age-determined.","PeriodicalId":12096,"journal":{"name":"Eye science","volume":"1 1","pages":"151-5"},"PeriodicalIF":0.0,"publicationDate":"2016-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75422395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eye sciencePub Date : 2016-04-18DOI: 10.21037/JES.2016.04.11
Hongpeng Li, Linxing Chen, H. Fang, Hongxing Diao, Wenyan Liu
{"title":"Analysis of different vision charts used for visual acuity assessment after retinal surgery.","authors":"Hongpeng Li, Linxing Chen, H. Fang, Hongxing Diao, Wenyan Liu","doi":"10.21037/JES.2016.04.11","DOIUrl":"https://doi.org/10.21037/JES.2016.04.11","url":null,"abstract":"BACKGROUND\u0000Different visual acuity chart can be targeted to evaluate the visual function of patients with different eye diseases. We conducted a comparative analysis of the digital logarithm of the minimum angle of resolution (LogMAR) vision chart and the standard logarithmic vision chart for the measurement of visual acuity after retinal detachment surgery.\u0000\u0000\u0000METHODS\u0000We used the digital LogMAR vision chart and the standard logarithmic vision chart to measure the visual acuity of 100 patients (100 eyes) who underwent retinal detachment surgery at our hospital using the LogMAR recording method and compared the differences between the mean measurements obtained by both methods for all patients and for different age groups.\u0000\u0000\u0000RESULTS\u0000When all of the patients were analyzed, the mean visual acuity differed between the digital LogMAR vision chart and the standard logarithmic vision chart by -0.07 LogMAR units. No significant difference was observed in the mean visual acuity between the two vision charts in the 10-20 year and 21-40 year age groups (P > 0.05), while a significant difference was observed in post-operative mean visual acuity between the two vision charts for patients aged 41-65 years (P < 0.05).\u0000\u0000\u0000CONCLUSIONS\u0000Both the digital LogMAR vision chart and the standard vision chart were effective and reliable for the measurement of visual acuity. The visual acuity measured by the standard vision chart was higher than that measured by the digital LogMAR vision chart. We recommend using the digital LogMAR vision chart as the preferred chart for measuring visual acuity after retinal detachment surgery.","PeriodicalId":12096,"journal":{"name":"Eye science","volume":"17 1","pages":"167-70"},"PeriodicalIF":0.0,"publicationDate":"2016-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79244097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eye sciencePub Date : 2016-04-18DOI: 10.21037/JES.2016.04.12
Jiakui Wang, Tzu-Lun Huang, P. Su, P. Chang
{"title":"An updated review of long-term outcomes from randomized controlled trials in approved pharmaceuticals for diabetic macular edema.","authors":"Jiakui Wang, Tzu-Lun Huang, P. Su, P. Chang","doi":"10.21037/JES.2016.04.12","DOIUrl":"https://doi.org/10.21037/JES.2016.04.12","url":null,"abstract":"Diabetic macular edema (DME) is a major sight-threatening cause in diabetic patients. We review the long-term outcome of four approved pharmacotherapy for treating DME, including intravitreal injections of corticosteroids (dexamethasone implants and fluocinolone acetonide inserts) and anti-vascular endothelial growth factor (VEGF) (ranibizumab and aflibercept). They all show superior ability to improve vision and reduce macular thickness, comparing with sham injections or macular focal/grid laser treatment. Anti-VEGF agents result in low incidence of severe ocular or systemic adverse effects, but glaucoma and cataract should be aware after intravitreal corticosteroids. Prompt treatment with these agents can lead to a better outcome","PeriodicalId":12096,"journal":{"name":"Eye science","volume":"29 1","pages":"176-83"},"PeriodicalIF":0.0,"publicationDate":"2016-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86659707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}