Evidence Based Women's Health Journal最新文献

{"title":"Effect of Laparoscopic Ovarian Drilling on Outcomes of In-Vitro Fertilization in Clomiphene-Resistant Women with Polycystic Ovary Syndrome","authors":"H. Sammour, Wessam Magdy Abuelghar, R. Kamel, A. Abd El-Rahim","doi":"10.21608/ebwhj.2022.167044.1210","DOIUrl":"https://doi.org/10.21608/ebwhj.2022.167044.1210","url":null,"abstract":"","PeriodicalId":12080,"journal":{"name":"Evidence Based Women's Health Journal","volume":"97 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85900136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Nifedipine on Uterine and Middle Cerebral Artery Doppler in Pre-Eclampsia Patients","authors":"S. Mohamed, H. Shalaby, Mohamed Eid","doi":"10.21608/ebwhj.2022.166468.1207","DOIUrl":"https://doi.org/10.21608/ebwhj.2022.166468.1207","url":null,"abstract":"Background: Preeclampsia AKA PE was defined based on NICE guidelines as new hypertension presenting after 20 weeks with significant proteinuria. Severe pre-eclampsia is pre-eclampsia with severe hypertension and/or with symptoms, and/or biochemical and/or hematological impairment. Nifedipine is used for control of blood pressure in cases with preeclampsia aiming to prevent rise of blood pressure during expectant management of these cases. Objective: To evaluate changes in uterine artery and middle cerebral artery Doppler indices before and a week after Nifedipine administration for control of blood pressure in PE patients. Design: Prospective observational study over six months that started to recruit patients from Mansoura university hospitals antenatal care clinics from May, 2019 to December, 2019. Methods: Doppler on uterine and middle cerebral artery was done before and a week after administration of Nifedipine. Dose of nifedipine: starting dose 10 mg orally twice daily increased after 48hs according to response. Maximum safe dose is 60 mg per day in dividing doses 8 hours apart. Drug stopped immediately if severe side effects like sudden hypotension where IV fluids and corticosteroid to support blood pressure will be commenced immediately. If no respons after maximum dose of medication conservative management was abandoned and delivery took place. Main Outcome Measure: Changes in uterine and middle cerebral artery Doppler indices before and after Nifedipine administration. Use of these changes to evaluate decisions for conservative management in preeclampsia patients. Conclusion: Nifedipine is a valid option to treat hypertensive patients, however more extended studies on fetal effects are required.","PeriodicalId":12080,"journal":{"name":"Evidence Based Women's Health Journal","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87166456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of maternal serum magnesium level in eclampsia, preeclampsia and normal pregnant women admitted to El-Shatby Maternity Hospital","authors":"M. Farag, Z. El-Baz, El-Habashy Ahmed","doi":"10.21608/ebwhj.2022.163590.1201","DOIUrl":"https://doi.org/10.21608/ebwhj.2022.163590.1201","url":null,"abstract":"Background: Preeclampsia is a pregnancy multisystem disorder of unknown etiology. It is a significant cause of maternal and fetal morbidity and mortality. Magnesium may be physiologically important in blood pressure regulation whereas changes in magnesium levels could contribute to the patho-etiology of hypertension. Objective: comparison of the level of serum magnesium between preeclamptic, eclamptic patients and normal pregnant women. Materials and Methods: This case-control study was conducted on 250 patients at EL-Shatby Maternity University Hospital. 100 cases were preeclamtic, 100 cases were eclamptic and 50 cases were normal pregnancy (control group) . Results: Serum magnesium was higher in eclamptic and preeclamptic women compared to normal pregnant women. In eclampsia serum magnesium was markedly reduced than in pre-eclampsia. Conclusion : Serum magnesium is lower in PET cases versus normal pregnant cases. This might supported the hypothesis that Mg deficiency might be the causative factor in the development of preeclampsia and eclampsia.","PeriodicalId":12080,"journal":{"name":"Evidence Based Women's Health Journal","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78740304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatitis C Vertical Transmission (Laboratory Testing in Mothers and Neonates)","authors":"A. Abdelaziz, A. Kandil","doi":"10.21608/ebwhj.2022.169356.1218","DOIUrl":"https://doi.org/10.21608/ebwhj.2022.169356.1218","url":null,"abstract":"Background: Infection with the hepatitis C virus (HCV) affects 2%-3% of the world’s population. Egypt has the highest recorded prevalence of HCV in the world, reaching 14.7% for HCV-antibody (Ab) positivity among 15- to 59-year-olds in 2008. The natural history of vertically acquired HCV in children is uncertain, with the majority (73–92%) suffer continual infectious state but stay asymptomatic in the first few years. Aim: To investigate the diagnostic performance and characteristics of maternal HCV RNA testing in predictability of developing neonatal positive HCV Ab and positive HCV RNA. Methodology: At Benha University hospital from 2016 to 2018 Obstetrics and Gynecology department in collaboration with Hepatology, Gastroenterology and infectious disease department, HCV RNA +ve pregnant women were recruited into a cohort study from gestation to 6 months after delivery. Maternal and child research data were collected via HCV antibody testing and HCV RNA testing. Results: Maternal HCV RNA had statistically significant low diagnostic performance and characteristics in prediction of developing neonatal positive HCV Ab (AUC = 0.749, SE = 0.050, Pvalue < 0.001, 95% CI = 0.651 – 0.847 , cutoff ≥ 4.7, sensitivity = 0.839, specificity = 0.614) and positive HCV RNA (AUC = 0.787, SE = 0.080, P value = 0.007, 95% CI = 0.629 – 0.944, cutoff ≥ 9.2 sensitivity = 0.625, specificity = 0.870). Conclusions: Possibly, there is inadequate or incomplete screening of vulnerable due to, low maternal health-care compliance. Complete testing of all neonates at risk of vertically acquired HCV requires to be noted in medical recording system as early management intervention could influence disease course.","PeriodicalId":12080,"journal":{"name":"Evidence Based Women's Health Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75228973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Trans Obturator Tape (TOT) in the Treatment of Urinary Incontinence","authors":"A. Abd El-Raouf, A. Abdel Rahim, Ahmed Mohamed, M. Ragab","doi":"10.21608/ebwhj.2022.168012.1215","DOIUrl":"https://doi.org/10.21608/ebwhj.2022.168012.1215","url":null,"abstract":"Aim: To evaluate the role of trans obturator tape (TOT) insertion in the treatment of women with mixed urinary incontinence using subjective and objective measures. Patient and Methods: Included 25 female patients with mixed urinary incontinence with failure of response to medical treatment and other forms of conservative methods underwent trans obturator tape insertion (TOT) and followed until six months postoperative. Results: TOT was successful in treatment of stress urinary incontinence, but 60% successful in treatment of urge incontinence 6 months post-operative. Conclusion: TOT is an effective operation for the treatment of stress urinary incontinence; however, large studies with long term follow-up are needed to confirm that finding.","PeriodicalId":12080,"journal":{"name":"Evidence Based Women's Health Journal","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76687417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Controversy over the use of Fresh Versus Frozen-Thawed Testicular Sperm in Men with Non-Obstructive Azoospermia Undergoing ICSI","authors":"Sherif Gafaar, Anis Hebisha, Mohamed Eldeeb, S. Galal","doi":"10.21608/ebwhj.2022.172594.1222","DOIUrl":"https://doi.org/10.21608/ebwhj.2022.172594.1222","url":null,"abstract":"Objective: The aim of this study is to compare fresh versus frozen-thawed TESE-ICSI in Egyptian men with NOA regarding fertilization and pregnancy rates. Moreover, the study aimed at finding the effect of testicular sperm motility on various ICSI outcomes. Study Design: A case control nonrandomized study Materials and Methods: The study was approved by the medical ethical committee of the Faculty of Medicine, Alexandria University. It was conducted on 226 consecutive TESE-ICSI cycles that were performed at El Shatby ICSI center Alexandria university, Egypt, between October 2017 and August 2018. Patients suffering from non-obstructive azoospermia were included in the study. Patients with history of negative testicular biopsy were excluded from the study. In addition, female partners with uncorrected uterine pathology and those with history of recurrent implantation failure were also excluded. The decision of fresh or frozen TESE was taken according to logistic factor (the availability of the andrologist). Samples were either directly used for ICSI or cryopreserved . Results: 63 fresh TESE and 163 frozen-thawed TESE ICSI cycles were performed. The fresh and the frozen-thawed TESE groups had comparable fertilization (67% and 55% respectively, p=0.101 ) and clinical pregnancy rate (42.6% and 39% respectively, p= 0.647 ). The clinical pregnancy rate increased significantly when motile versus immotile sperms (49% Vs 15.4% respectively, p <0.001 * ) were used for injection. Conclusion : ICSI cycles injected by fresh or frozen- thawed TESE have comparable fertilization and clinical pregnancy rates. However, injected oocytes with motile sperms leads to significant increase in fertilization and clinical pregnancy.","PeriodicalId":12080,"journal":{"name":"Evidence Based Women's Health Journal","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82001067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of COVID-19 Infection on the Maternal and Perinatal Outcome of Pregnancies Associated with Preeclampsia","authors":"R. Elkhateeb, Hesham Fares","doi":"10.21608/ebwhj.2022.167996.1211","DOIUrl":"https://doi.org/10.21608/ebwhj.2022.167996.1211","url":null,"abstract":"Objectives: To compare the severity and complications of preeclampsia in the presence and absence of COVID-19 infection Methods: A cross-sectional study was carried out at Minia Governate isolation Hospitals which have a standard procedure for monitoring and testing COVID-19. The study enrolled 345 pregnant women after considering eligibility criteria. One hundred fifteen cases were positive for COVID-19 infection compared with randomly chosen control cases with a ratio of 1:2 of COVID-19-negative pregnant women. Result: The incidence of preeclampsia in COVID-19-infected pregnant women was 31.3% (36 cases), while 42 cases in the non-COVID-19 group had preeclampsia with an incidence of 18.3%. There was a high incidence of maternal complications in the study group (ICU admission incidence was 72.2% versus 45.2%, and maternal mortality was 41.6% versus 38%). Fetal complications were higher in the study group. Conclusion: The development of preeclampsia in COVID-19 patients is associated with hazardous maternal and fetal outcomes. It increases the need for ICU admission, invasive ventilation support, maternal and perinatal mortality.","PeriodicalId":12080,"journal":{"name":"Evidence Based Women's Health Journal","volume":"117 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79386215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of COVID-19 on Premenstural Tension Syndrome Among Qalyoubia Governorate Physicians, A Cross Sectional Study","authors":"E. Shebl, Eman Ajwa, Wael Naeem, A. Negm","doi":"10.21608/ebwhj.2022.163904.1204","DOIUrl":"https://doi.org/10.21608/ebwhj.2022.163904.1204","url":null,"abstract":"Background: The late luteal phase of a woman's menstrual cycle is associated with a collection of a variety of mood-related, physical, and behavioral symptoms that are referred to together as premenstrual symptoms. The purpose of this research was to investigate whether or not there is a correlation between COVID-19-induced premenstrual symptom syndrome (PTSS) and premenstrual symptoms in Japanese high school students. Material and Methods: A cross sectional study hospital based study via cluster sampling technique Qalyoubia governorate, Egypt (from Jan 5 to March 21, 2022) was conducted. Two hospitals (sampling unit) were chosen randomly, all non -pregnant female physicians in child bearing period (15-49 years), of different departments in the selected hospitals were invited to participate in the study. Results: Our data and work indicate that there is increase in PMS .PMDD during the pandemic among the studied group, these changes were linked to psychological stress related to the covid pandemic. Our study showed a relation between front line work and the post traumatic stress symptoms this is in line with previous studies in literature that suggest worsening of PMS symptoms during stressful events, no one can deny that front line work is more stressful than those on the second line which confirm the role of stress in these events. When we compared the difference in mean premenstrual symptoms total score and intensity of menstrual pain our study confirmed the relation in the group of PTSS. According to the results of regression analysis there was a correlations of significance between BMI and FCV-19 score and a correlations of high significance between intensity of menstrual pain and IES-R score of the study group characteristics and the total premenstrual score. Conclusion: In the era of covid many aspects of life has been changed, covid not only affect the general health but also many aspects of affection of menstrual pattern and premenstrual tension , social life has been affected deeply by covid. its negative impact should be dealt with .in this study we examined the psyclogical distress effects of covid on female physicians and its negative impact on premenstrual tension among and there social life affection.","PeriodicalId":12080,"journal":{"name":"Evidence Based Women's Health Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80196985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Serum Levels of Afamin and Tumor Necrosis Factor-α during The First Trimester might be used as Early Predictors for Gestational Diabetes Mellitus in Euglycemic Pregnant women","authors":"Ali Bendary, Y. Marei","doi":"10.21608/ebwhj.2022.167998.1213","DOIUrl":"https://doi.org/10.21608/ebwhj.2022.167998.1213","url":null,"abstract":"","PeriodicalId":12080,"journal":{"name":"Evidence Based Women's Health Journal","volume":"189 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77351364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endometrial Spiral Artery Doppler Parameters, Vitamin D, B2 Glycoprotien 1 Assessment in Cases with Recurrent Unexplained Pregnancy Loss","authors":"Wael El Gazayerli, S. El Sayed, Tarek Tappozada","doi":"10.21608/ebwhj.2022.169208.1217","DOIUrl":"https://doi.org/10.21608/ebwhj.2022.169208.1217","url":null,"abstract":"Background: Recurrent pregnancies loss (RPL) is physically andemotionally devasting situation for the parents, along with difficult situationfor obstetrician to handle. Aim of the Work: The present study aimed at investigation of the significanceof various etiology in relation to pregnancy outcome in cases ofunexplained recurrent pregnancy loss. Materials And Methods: It is a retrospective analysis of 100 patientswho presented to El-Shatby maternity university hospital, betweenMay 2017 to October 2018, with history of two or more unexplained earlytrimester abortions fullfiling the common investigations done for thesecases. all the patients during mid-luteal phase, examined by transvaginal3D pulse Doppler ultrasound to detect endometrial perfusion with measuringin the sera 25-hydroxy vitamin D3 and B2 glycoprotein 1 antibodieswhich is a marker of antiphospholipid syndrome. evaluation of uterineartery blood flow and subendometrial blood flow, detection uterine arterypulsatility index (UAPI) and subendometrial blood flow presented by the indiciesvascularisation index (VI), flow index (FI) and vascular flow index(VFI). Results and Conclusion: All of the studied parameters namely; doppler indices, vitamin D level and B2glycoprotien were significantly related to the incidence of the pregnancy loss and should be tested in those particular category of women who are at risk of recurrent pregnancy loss..","PeriodicalId":12080,"journal":{"name":"Evidence Based Women's Health Journal","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90248916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}