{"title":"PATTERN AND OUTCOME OF RENAL DISEASES IN HOSPITALIZED CHILDREN\u0000IN TIKUR ANBESSA SPECIALIZED TEACHING HOSPITAL,\u0000ADDIS ABABA, ETHIOPIA.","authors":"Kebede Mola, Damte Shimelis","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Renal diseases are major causes of morbidity and mortality in pediatric practice. Pediatric patients\u0000with renal disease, especially younger ones may present with nonspecific signs and symptoms unrelated to the urinary\u0000tract. Unexplained fever or failure to thrive may be the only manifestation. Most children with renal diseases\u0000in our hospital arrive very late either because of inadequate health awareness among the parents or failure of recognizing\u0000the symptoms of renal diseases at a lower health care level. This review will highlight the symptoms of\u0000renal diseases at presentation and outcomes of treatment in children in a major referral hospital.</p><p><strong>Methods: </strong>A cross-sectional retrospective chart review was done over a period of 3 years (June, 2012 to May,\u00002015) in 381 admitted children (Birth-17 years) at Tikur Anbessa Specialized Teaching Hospital in Addis Ababa,\u0000Ethiopia.</p><p><strong>Results: </strong>Out of 14521 pediatric ward admissions in the study period, kidney diseases accounted for 473 admissions\u0000in 381 children, accounting for 3.3% of all admissions. The three most common renal diseases observed were\u0000congenital anomalies of the kidney and urinary tract (CAKUT) seen in 127 children (26.8%), followed by\u0000nephrotic syndrome in 80 children 16.9% and acute glomerulonephritis in 58 children (12.2%). Other renal diseases\u0000observed were urinary tract infection 8.0%, urolithiasis 6.7%, Wilm’s tumor 6.3%, acute kidney injury 4.2%\u0000and chronic kidney disease 4.0%. Other less frequently detected diseases were bladder exstrophy, lupus nephritis,\u0000Henock shonlein Purpura nephritis and prune-belly syndrome.\u0000Out of 381 children 207 (54.3%) recovered normal renal function, 20(5.2%) remained with proteinuria, 13(3.4%)\u0000progressed to chronic kidney disease and 11(2.9%) died. Sixty one nephrotic children (76.3%) achieved remission\u0000but 17 children (21.3%) remained with proteinuria; one steroid resistant child died of end stage renal disease. Ten\u0000children (2.6%) with different renal diseases were lost to follow-up and 5 (1.3%) discharged against medical advice.</p><p><strong>Conclusions: </strong>This data reflects that many of the renal diseases are preventable or potentially curable. Therefore,\u0000improvement of pediatric renal services and training of health workers would help in early detection and treatment\u0000of these conditions leading to reduction in their morbidity and mortality.</p>","PeriodicalId":11937,"journal":{"name":"Ethiopian Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35582412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}