European Journal of Medicine and Natural Sciences最新文献

{"title":"Uterine Leiomyofibroma in the Gynecological Pathology of the Emergency County Clinical Hospital Saint Andrew the Apostle Constanta","authors":"C. Tomescu, Ana-Maria Brezeanu, D. Brezeanu, A. Tomescu, Cadar Emin","doi":"10.2478/ejnsm-2023-0006","DOIUrl":"https://doi.org/10.2478/ejnsm-2023-0006","url":null,"abstract":"Abstract Benign pelvic-abdominal tumor formations are an important part of female pelvic pathology. Uterine fibroids occupy an important place in gynecological benign pathology, among pelvic-abdominal tumors, A retrospective study was performed for a period of 5 years (2015-2019) on a number of 1505 patients admitted to the Clinical Emergency Hospital St. Andrew the Apostle Constanta, on the two departments of Obstetrics-Gynecology OG I and OG II. The patients were followed according to the following criteria: age, origin, symptoms, and the type of surgery performed.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"11 1","pages":"55 - 64"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78953238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Course and Treatment of Human Brucellosis in a Sample of Hospitalized Cases in Albania","authors":"Dritan Rami, A. Ylli, P. Pipero, E. Ramosaço, A. Harxhi","doi":"10.2478/ejnsm-2023-0007","DOIUrl":"https://doi.org/10.2478/ejnsm-2023-0007","url":null,"abstract":"Abstract Brucellosis remains a public health problem in many Mediterranean countries. In this work are presenting data of human brucellosis clinics and treatment in a sample of hospitalized patients. Methods: All patient charts at regional hospital in Gjirokastra, Albania were systematically reviewed, during the period 2016-2021. All hospitalized patients with a laboratory confirmed diagnoses of brucellosis were included in the study. Variables of interest were clinical symptoms, clinical course and treatment provided. Sub-acute brucellosis was defined as clinical persistence of 3-12 months while cases with clinical symptoms persisting for ≥12 months were defined as chronic brucellosis. Results: 79% of the 86 patients were male and residing in rural areas. Fever, profuse sweating and arthralgia were the most common clinical signs. Around 70% of the brucellosis patients showed all these three symptoms. Despite a systematic tendency for more frequent presence of high fever, increased sweating and arthralgia on younger patients we could not find statistically significant differences among demographic categories. 18.6% of cases presented persistence of clinical signs after at least 3 months from the moment of the diagnoses. Almost 7% of the cases were classified as chronic cases. 75.6% of all patients were treated with a combination of doxycycline and ceftriaxone antibiotic regime. Conclusions: The massive use of a cephalosporin in treatment of brucellosis cannot be justified and may reflect a larger problem related to population awareness and health provider attitudes concerning antibiotic use in Albania. The results of this study may assist future interventions to improve brucellosis case management at hospitals or primary health care level as well as national measures at a larger scale for control of the disease.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"26 1","pages":"65 - 74"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90637916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of a Spectrophotometric Method of Some Antidepressant Drugs","authors":"Cadar Emin, S. Rodica, A. Ionescu, Anca M. Safta, C. Tomescu","doi":"10.2478/ejnsm-2023-0001","DOIUrl":"https://doi.org/10.2478/ejnsm-2023-0001","url":null,"abstract":"Abstract Although the causes of depression include a wide range of conditions, from neurodegenerative to thyroid, they all have one common denominator, changes in the brain. Depression can be located in multiple brain regions simultaneously, which may be derived from a common molecular abnormality found in neurons in many brain regions. Abnormalities of receptors or impulse transmission could be the answer. In this work, a simple and accurate spectrophotometric method was developed for the analysis of escitalopram oxalate in various pharmaceutical formulations. In this method, absorbance was measured at 238 nm for escitalopram oxalate. Method validation parameters were studied. The method can be used for quality control of pharmaceutical forms containing escitalopram. Also, by the same method, the actual active substance concentrations compared to those listed on the package, the standard deviations and the relative standard deviations.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"64 1","pages":"1 - 9"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91044278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brown Seaweeds from Black Sea Coast as an Important Source of Bioactive Compounds of Interest for Human Health","authors":"A. Drăgan, R. Sîrbu, Emin Cadâr","doi":"10.2478/ejnsm-2023-0010","DOIUrl":"https://doi.org/10.2478/ejnsm-2023-0010","url":null,"abstract":"Abstract For human nutrition, algae are important organisms that can offer essential compounds and new bioactive substances with pharmaceutical and medicinal value. Macroalgae contain nutritional elements such as lipids, proteins, vitamins and minerals and they are used as food supplements because they are known to be high in mineral content. There are a lot of nutritionally compunds that can be identified in algae such as polysaccharides, polyphenols, diterpenes, sterols, carbohydrates, peptides, polyunsaturated fatty acids, pigments and dietary fibers. Nutraceuticals are confirmed to be used as medicines because they are a good protector against chronic diseases and they have physiological benefits. Algae bioactive compounds could be used as an anticoagulant, antioxidant, anti-inflammatory, antibacterial, antimicrobial, antifungal, anticancer, antiviral, antidiabetic, antiobesity, antihypertensive and hypercholesterolemic nutraceuticals. Although only some of the algae have been studied properly for their chemical composition and properties, they are a considerable biological resource with ability for use as a raw material. In this paper the compounds from red and brown algae from the Romanian seaside are evaluated as sources of biologically active ingredients with benefits in human health.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"1 1","pages":"100 - 113"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79931551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plastic Pollution in Albania: Survey on Citizen’s Perceptions and Attitudes","authors":"Ani Bajrami, F. Osmani, Elvisa Sokoli","doi":"10.2478/ejnsm-2023-0004","DOIUrl":"https://doi.org/10.2478/ejnsm-2023-0004","url":null,"abstract":"Abstract Plastics are polymers synthesized from petrochemicals or from biomass raw materials. In recent decades, worldwide plastics production has increased exponentially. An estimated 8.3 billion tons of plastic have been produced worldwide resulting in an estimated 6.3 billion tons of plastic waste disposed in landfill or discarded into the natural environment. Plastic is widely used: is inexpensive, durable, resource efficient and easily attainable. The article makes some preliminary observations based on questionnaire data distributed through probability stratified random sampling method between November 2021 and July 2022. The data provides some useful insights into citizens perceptions and attitudes about plastic pollution. Majority of respondents agree on the fact that plastic pollution is harmful to the environment (94%). Additionally, 77.1% of respondents agree both on the fact that nature conservation activities are necessary and successful if community or citizens are involved. Strategies which can be used to reduce plastic pollution need to provide further incentives for public participation. An example is using citizen science, to address and mitigate plastic pollution both at local and national level.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"20 1","pages":"36 - 42"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80993050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutical Properties of Bioactive Compounds Extracted from Ganoderma lucidum Species on Acute and Chronic Diseases","authors":"Carolina Pascale, R. Sîrbu, Emin Cadâr","doi":"10.2478/ejnsm-2023-0008","DOIUrl":"https://doi.org/10.2478/ejnsm-2023-0008","url":null,"abstract":"Abstract Ganoderma lucidum or Reishi is a medicinal mushroom of significant importance that is being used for the prevention and treatment of various diseases, due to its numerous pharmacological and therapeutic properties. The Ganodermataceae family is diverse, but the focus is on the lucidum species because of its specific biologically active macromolecules such as polysaccharides, triterpenoids, steroids, phenolic compounds, lactones, and fatty acids that were isolated from the mycelia and fruiting bodies. Ganoderma lucidum species have many benefits over the immune system (promoting health) and properties such as: anti-tumoral, anti-inflammatory, anti-allergic, anti-viral, anti-bacterial and antioxidant. Based on the literature, triterpenoids and polysaccharides are the most abundant active compounds that possess anti-diabetic, hepatoprotective, cytotoxic and anti-hypertensive effects. A review of the literature showed that there are very few papers that studied semisolid dosage forms preparations based of Ganoderma lucidum extract to have been used on damaged skin and skin diseases, neither have there been enough studies on its anti-aging properties.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"37 1","pages":"75 - 88"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87326249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mandatory COVID-19 Vaccination and Free Self-Determination in the Health Field in Italy","authors":"Emanuela Furramani","doi":"10.2478/ejnsm-2023-0002","DOIUrl":"https://doi.org/10.2478/ejnsm-2023-0002","url":null,"abstract":"Abstract The COVID-19 pandemic and the issues related to health emergency management have raised concerns about fundamental rights protection. One of the most complex and contentious issues in doctrine and jurisprudence is the introduction of mandatory COVID-19 vaccination for specified categories of subjects, such as healthcare workers and individuals of a specific age range, as occurred in Italy. The debate in Italy over the mandatory COVID-19 vaccination requirement focuses on whether this obligation interferes with the individual’s fundamental right to free self-determination as guaranteed by Article 32 of the Italian Constitution. In jurisprudence and doctrine, conflicting opinions are noted concerning this topic. Part of the doctrine argue that mandatory COVID-19 vaccination compromises some fundamental rights guaranteed by the Italian Constitution, such as the right to free self-determination and respect for human dignity. Other opinions find the basis of the vaccination in the community’s best interests, citing Article 32 of the Italian Constitution, which allows for the imposition of compulsory health treatment to safeguard citizens’ health. In this regard, the issue of mandatory COVID-19 vaccination requires a reflection on the balance of two fundamental rights: the individual right to free self-determination and the community’s interest in terms of protecting public health.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"15 1","pages":"10 - 22"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78760216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Gait in Albanian β-thalassemia Patients","authors":"G. Pano","doi":"10.2478/ejnsm-2023-0003","DOIUrl":"https://doi.org/10.2478/ejnsm-2023-0003","url":null,"abstract":"Abstract One of the most prevalent genetic diseases in the world is beta thalassemia. Hemoglobin synthesis is decreased by the blood condition beta thalassemia. Patients with thalassemia exhibit a range of bone problems, including as spinal deformities, osteopenia and osteoporosis, as well as growth failure. This study’s main goal was to evaluate gait and balance in Albanian β-thalassemia patients. In this study, 18 participants aged 17 to 29 years old (5 males and 13 females) from three distinct epidemiological cities in Albania took part. Gait analysis was performed using “T&T medilogic medizintechnik gmbh” wi-fi insoles. “General Gait Parameters”, results of the “Effective Foot Length, left [%]” parameter mean results [67.59%], reveals approx a 2% difference compared with the relative normative mean [69.7%]. Also, “Effective Foot Length, left [%]” mean results [65.49%], reveals approximately a 3.5% difference compared with the relative normative mean [69.7%]. “General Gait Parameters”, data comparisons revealed statistically significant differences between “is” and “nom.” measurements for the following variables: “Rel Double Step Length”, “Double Step Duration”, “Effective Foot Length Right” and “Width Of Gait Right” (p<0.005). Results for the rest of the variables shwed a not statistically significant difference. The aim of the study was to assess the gait parameter in Albanian individuals with thalassemia. Based on the result of the “General Gait Parameters”, data reveal a difference in the % of the average gait line which is related to effective distribution in the insole length showing a specific indication of insecure gait. According to the findings, gait issues are a significant health issue for beta thalassemia patients which are most likely caused by disease-related side-effects such high calcium levels after blood transfusions, inactivity caused by insufficient muscle mass, and all other health-related disease conditions. It is advised that the gait analysis exam to be included in their regular health check-ups. Future studies should be conducted involving larger ß-thalassemia patients take into account the unique state of this category to better evaluate the gait problems related with general static and dynamic posture problems. Clinicians’ health specialists and rehabilitation experts when planning B-Thal rehabilitation programs sholud use gait analysis exam as a regular health check-up.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"149 1","pages":"23 - 35"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72576228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of Patient Satisfaction with Health Care: A Literature Review","authors":"Rezarta Kalaja","doi":"10.2478/ejnsm-2023-0005","DOIUrl":"https://doi.org/10.2478/ejnsm-2023-0005","url":null,"abstract":"Abstract This research paper aims to explore the field of patient satisfaction in health care, by performing a literature review on existing healthcare articles that analyse determinants of patient’s satisfaction and theories on patient satisfaction assessment. Patient satisfaction is one of the most important factors to determine the success of health care providers. Determining the exact definition, determinants and characteristics of patients that influence satisfaction, as well as different theories on satisfaction, are highly discussed elements in the literature for a long period of time. The research instrument was a literature review by combining different view from many researchers. The literature was searched in databases such as Emerald, Medline/PubMed, Web of Science, ScienceDirect, Scopus. Patient satisfaction appears to play an important role in evaluation of service quality. From the literature review, it was observed that the main determinants of patient satisfaction were the demographic characteristics, expectations and experiences of the patients. Communication is also an extremely important element that affects patient satisfaction. Other research should be conducted to delve even more into this very important area of health care.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"1 1","pages":"43 - 54"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81368398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomedical Applications Based on Marine Collagen Obtained from the Jellyfish Species Rhizostoma Pulmo Extracted from the Black Sea","authors":"Ana-Maria Pesterau, R. Sîrbu, Emin Cadâr","doi":"10.2478/ejnsm-2023-0009","DOIUrl":"https://doi.org/10.2478/ejnsm-2023-0009","url":null,"abstract":"Abstract Due to its unique properties, collagen is used in various emerging fields such as the pharmaceutical and biomedical device industries, as well as in related fields: nutraceuticals, cosmetics, food, beverages and nutritional supplements. Marine gelatin, one of the biomaterials involved in food and medicinal research, is denatured collagen produced from acid, alkaline, or enzyme hydrolysis. Gelatin is a crucial ingredient for the food, pharmaceutical, medical, biomedical focusing on versatile applications. Jellyfish collagen is a valuable resource for bioplastics and biomaterials used in various health sectors. Recently, marine organisms have been considered viable sources of collagen because they do not harbor transmissible diseases. In particular, fish biomass, as well as the catches of other types of organisms, such as small fish, jellyfish, starfish, sea urchins, sponges, possess a significant content of collagen. The collagen extracted from the species Rhizostoma pulmo from the Black Sea basin is also part of the bioresources that can be used to obtain natural marine collagen from this type of invertebrates. The use of discarded or hither to unused biomass could contribute to the development of a sustainable collagen extraction process with a positive impact on the ecosystem. In the future it is desired to approach a world strategy that minimizes the amount of waste and that supports all three general objectives of sustainability: sustainable economic well-being, social well-being and environmental protection.","PeriodicalId":11935,"journal":{"name":"European Journal of Medicine and Natural Sciences","volume":"108 1","pages":"89 - 99"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80846051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}