{"title":"Challenges in Managing Multidrug-Resistant Infections Among Refugees: Clinical Experience During the Ukrainian War.","authors":"Josu Urbieta-Mancisidor, Jesús-Martín Treviño-Theriot","doi":"10.12890/2025_005338","DOIUrl":"https://doi.org/10.12890/2025_005338","url":null,"abstract":"<p><p>The war in Ukraine, initiated in 2022, triggered a massive humanitarian crisis with millions displaced. This population exodus posed significant healthcare challenges, including the spread of infections caused by multidrug-resistant (MDR) bacteria. Factors such as disrupted healthcare services, inappropriate antimicrobial use and environmental contamination contributed to increased bacterial resistance. In this context, in 2023 an 86-year-old Ukrainian migrant was treated in a Spanish hospital for severe infections complicated by MDR bacteria. During hospitalisation, complex resistant strains of <i>Pseudomonas aeruginosa</i> and <i>Klebsiella pneumoniae</i> were identified. Treatment was guided by culture results, though infections recurred multiple times. A literature review indicated that infections among displaced Ukrainians commonly involve Gram-negative bacteria such as <i>P. aeruginosa</i> and <i>K. pneumoniae</i>, often exhibiting high resistance levels. This underscores the urgent need for infection control strategies, improved antibiotic stewardship and enhanced epidemiological surveillance. Additionally, it highlights the importance of international cooperation and networked efforts in managing antimicrobial resistance during conflicts and mass displacement.</p><p><strong>Learning points: </strong>Multidrug-resistant (MDR) bacterial infections are frequent among displaced populations from conflict zones, presenting significant clinical challenges.Effective management requires multidisciplinary teamwork, stringent infection control measures and rational use of antibiotics.Enhanced international cooperation and surveillance systems are essential to combating antimicrobial resistance in crisis contexts.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005338"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Mimicker of Meningitis, Retropharyngeal Abscess and Cervical Spondylodiscitis - Acute Calcific Tendinitis of Longus Colli Muscle.","authors":"Chin Ben Soh, Kai Xiong Lim","doi":"10.12890/2025_005278","DOIUrl":"https://doi.org/10.12890/2025_005278","url":null,"abstract":"<p><strong>Introduction: </strong>Acute calcific tendinitis of the longus colli muscle can present with symptoms resembling severe conditions such as meningitis, an intracranial abscess, a retropharyngeal abscess or cervical spondylodiscitis.</p><p><strong>Case description: </strong>A 37-year-old Chinese female was admitted with neck pain, headache, fever and odynophagia, raising concerns for meningitis, a retropharyngeal abscess or cervical spondylodiscitis. The physical examination was unremarkable except for restricted neck movement and tenderness over right upper paravertebral area. Laboratory investigations were unremarkable. A CT scan of the neck showed nodular calcification just below the C1 anterior arch; MRI with contrast revealed T2-weighted hyperintensity with enhancement in the retropharyngeal space, along with minor oedema over the adjacent longus coli muscle. A final diagnosis of acute calcific tendinitis of longus colli was established, based on the radiological findings and clinical response to treatment.</p><p><strong>Discussion: </strong>Acute calcific tendinitis of the longus muscle is a rare inflammatory condition caused by the deposition of amorphous calcium hydroxyapatite crystals in the anterior C1-C2 disc space. Due to its anatomical location, inflammation will result in triggering similar symptoms as in meningitis, an intracranial abscess, a retropharyngeal abscess or cervical spondylodiscitis. CT and MRI imaging are the gold standard for diagnostic investigation; there are no formal treatment guidelines, and management is conservative, primarily involving analgesia.</p><p><strong>Conclusion: </strong>Clinicians should be aware that acute calcific tendinitis of the longus muscle can present with symptoms that mimic other severe conditions such as meningitis, an intracranial abscess, a retropharyngeal abscess or cervical spondylodiscitis.</p><p><strong>Learning points: </strong>Be aware of the presentation of acute calcific tendinitis of the longus colli muscle, which can mimic severe conditions such as meningitis, an intracranial abscess, a retropharyngeal abscess or cervical spondylodiscitis.Recognising the characteristic radiological findings of acute calcific tendinitis of the longus colli muscle is crucial to avoid unnecessary invasive and surgical interventions and ensure appropriate conservative management.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005278"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dylani Rosa Ávila Salcedo, Jorge Alejandro Ayala San Pedro, Julia Rábago Arredondo, Rodrigo Santiago Sánchez García
{"title":"Recurrent Acute Suppurative Thyroiditis Secondary to Pyriform Sinus Fistula Due to <i>Staphylococcus Sciuri</i> with Subclinical Hyperthyroidism in an Adult. A Diagnostic and Therapeutic Challenge.","authors":"Dylani Rosa Ávila Salcedo, Jorge Alejandro Ayala San Pedro, Julia Rábago Arredondo, Rodrigo Santiago Sánchez García","doi":"10.12890/2025_005360","DOIUrl":"https://doi.org/10.12890/2025_005360","url":null,"abstract":"<p><strong>Background: </strong>Acute suppurative thyroiditis (AST) caused by pyriform sinus fistula (PSF) is a rare condition in adults. PSF is a congenital malformation that can cause an infection of the thyroid gland, usually located on the left side. AST presents with symptoms similar to respiratory infections, which can make it difficult to diagnose. It is essential to consider PFS as a differential diagnosis due to its relationship with the recurrence of thyroid abscesses.</p><p><strong>Case report: </strong>We report the case of a 32-year-old woman who presented with neck pain and fever, initially mistaken for an upper respiratory infection. After 3 weeks, she was diagnosed with AST with an abscess in the left thyroid lobe. Drainage and initial antibiotic treatment (metronidazole and clindamycin) improved her condition. However, due to non-compliance with medical follow-up, the patient suffered a recurrence of the abscess and required a left thyroid lobectomy. The culture identified multidrug-resistant <i>Staphylococcus sciuri</i> and the patient was finally referred for a successful fistulectomy.</p><p><strong>Conclusion: </strong>AST due to PSF is uncommon in adults, with few documented cases. Initial treatment includes antibiotics and surgical drainage, although recurrence can occur if the risk factor is not eliminated. In this case, failure to comply with medical follow-up contributed to the recurrence. It is crucial to identify PSF as a causative factor early on and to carry out adequate follow-up to avoid serious complications.</p><p><strong>Learning points: </strong>Thyrotoxicosis can occur in up to 42% of cases of acute suppurative thyroiditis, making it less relevant to differentiate it from other causes of thyroiditis.In adults with no obvious risk factors, congenital malformations should be considered, especially when the condition affects the left lobe.To avoid recurrences, it is necessary to evaluate the pyriform sinus in any age group and patient adherence to medical instructions is essential.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005360"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peripheral Facial Palsy in Small Cell Lung Cancer with Mastoid Metastasis.","authors":"Mariana Gaspar, Mariana Marques Silva, Márcia Agostinho Pereira, Joana Silva, Nathalie Duarte","doi":"10.12890/2025_005329","DOIUrl":"https://doi.org/10.12890/2025_005329","url":null,"abstract":"<p><strong>Introduction: </strong>Peripheral facial palsy is commonly associated with benign self-limited conditions. In rare circumstances, it may be the manifestation of underlying malignancy.</p><p><strong>Case description: </strong>We present an unusual case of a 53-year-old woman with previously diagnosed small cell lung cancer (SCLC), who developed sudden-onset peripheral facial palsy. Imaging studies revealed mastoid metastasis with facial nerve involvement and venous sinus thrombosis, despite a normal MRI performed just one month prior. Despite ongoing treatment, the disease showed rapid progression culminating in the patient's death.</p><p><strong>Discussion: </strong>Metastatic involvement of the mastoid is extremely rare in SCLC. Such metastases can occur via haematogenous or meningeal spread, resulting in complex clinical phenotypes with mastoid involvement, including facial palsy and venous sinus thrombosis among others.</p><p><strong>Conclusion: </strong>This case emphasises the importance of individualised assessment in peripheral facial palsy and vigilance regarding unusual metastatic patterns in cancer patients. The rapid clinical deterioration despite appropriate treatment underscores both the aggressive nature of SCLC and the critical need for more effective treatment strategies.</p><p><strong>Learning points: </strong>Small cell lung cancer's neuroendocrine nature drives metastasis to unexpected territories, including the rarely affected mastoid region.In patients with peripheral facial palsy and malignancy risk factors, prompt imaging should be considered, even when other suspicious features are absent.Small cell lung cancer evolves rapidly in spite of treatment, requiring vigilance for metastatic complications despite reassuringly normal recent examinations.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005329"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tiago Dias da Costa, Marta Rodrigues, António Mateus-Pinheiro, Sónia Moreira
{"title":"Rhabdomyolysis as an Uncommon Manifestation of Anoctamin-5 Muscular Dystrophy.","authors":"Tiago Dias da Costa, Marta Rodrigues, António Mateus-Pinheiro, Sónia Moreira","doi":"10.12890/2025_005325","DOIUrl":"https://doi.org/10.12890/2025_005325","url":null,"abstract":"<p><strong>Background: </strong>Anoctamin-5 (ANO5) muscular dystrophy is a rare neuromuscular disease. Muscular weakness and impaired gait may be evident at the moment of diagnosis, serving as defining characteristics of additional muscular dystrophies. Rhabdomyolysis, on the other hand, is a rare presentation Understanding this phenotype is of great importance since it can go unnoticed by physicians, leading to misdiagnosis of metabolic myopathies or delayed diagnosis. We discuss a case of recurrent rhabdomyolysis due to ANO5 muscular dystrophy.</p><p><strong>Case report: </strong>A 34-year-old man was referred to our Reference Centre for Hereditary and Metabolic Diseases due to incidentally elevated creatine kinase levels of 4369 U/l (normal value: < 171 U/l) in the context of acute renal colic. He described a 10-year history of progressive myalgia induced by physical activity, particularly in the lower extremities, muscle spasms, and sporadic reddish to brown urine. Although no muscle weakness was detected upon neurological examination, bilateral calf hypertrophy was noted. A comprehensive laboratory analysis was conducted to exclude acquired causes of rhabdomyolysis, including electrolyte abnormalities, endocrine disruptions, and autoimmune myopathies. Considering the high suspicion of an inherited aetiology, we proceeded with next-generation sequencing of rhabdomyolysis-related genes. Genetic testing revealed a c.1180+6t>Cp homozygous mutation in ANO5 gene, which confirmed anoctamin-5 muscular dystrophy.</p><p><strong>Conclusions: </strong>ANO5 muscular dystrophy is a rare cause of inherited rhabdomyolysis. Understanding this phenotype is crucial for accurate and timely diagnosis. Currently, there is no specific treatment for this condition, but management should include avoiding heavy muscle training and use of statins.</p><p><strong>Learning points: </strong>Anoctamin-5 (ANO5) muscular dystrophy is a rare neuromuscular disease originated by homozygous mutations in ANO5, a gene encoding a protein with the same name located on chromosome 11. ANO5 is a calcium-activated chloride channel that is highly expressed in heart and skeletal muscle. It is a rare cause of inherited rhabdomyolysis. Understanding this phenotype is crucial for accurate and timely diagnosis.We must emphasize how meticulous medical history taking along with a high index of suspicion are essential to diagnose this disease.Currently, there is no specific treatment for this condition, but management should include avoiding heavy muscle training and use of statins.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005325"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary Tumour Embolism from Gastric Adenocarcinoma Causing Respiratory and Cardiac Failure may not be Identified on Standard Ante-Mortem Imaging.","authors":"Konstantīns Ščerbakovs, Valentīna Mihejeva, Sergejs Dubencovs, Evelīna Stunda, Dace Žentiņa","doi":"10.12890/2025_005294","DOIUrl":"https://doi.org/10.12890/2025_005294","url":null,"abstract":"<p><p>Pulmonary tumour embolism is severe complication of malignancy, often presenting with progressive dyspnoea and respiratory failure. Due to their non-specific symptoms and absence of clear imaging findings, diagnosis is frequently delayed or made post-mortem. This is a case of previously undiagnosed gastric adenocarcinoma presenting with rapidly worsening respiratory symptoms: hypoxaemia, pulmonary hypertension and heart failure. Standard imagining - computed tomography angiography and echocardiography - provide indirect evidence, definitive diagnosis of pulmonary tumour embolism confirmed post-mortem. This case highlights the diagnostic challenges associated with a pulmonary tumour embolism and underscores the importance of early suspicion of malignancy-related complications in cases of progressive respiratory and cardiac failure without radiographic evidence of pulmonary embolism.</p><p><strong>Learning points: </strong>Standard diagnostic imaging lacks specificity and fails to detect pulmonary tumour embolism. Computed tomography angiography and echocardiography provide indirect evidence, but definitive diagnosis often requires histopathological confirmation, frequently post-mortem.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005294"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suzanne K Veneman, Stephanie E Veneman, Thiemo F Veneman
{"title":"Temporomandibular Joint Dislocation After Long-Term Mechanical Ventilation.","authors":"Suzanne K Veneman, Stephanie E Veneman, Thiemo F Veneman","doi":"10.12890/2025_005340","DOIUrl":"https://doi.org/10.12890/2025_005340","url":null,"abstract":"<p><strong>Introduction: </strong>Dislocations of the temporomandibular joints (TMJ) are relatively common and occur in as many as 7% of the entire population at some point in their lives. Anterior dislocations are the most common and are defined as the excessive forward movement of the mandibular condyle out of the glenoid fossa beyond the articular eminence with complete separation of the articular surfaces. However, anterior bilateral TMJ dislocation after intubation described in this case report, is a very uncommon complication.</p><p><strong>Case description: </strong>A 43-year-old woman with an unremarkable medical history presented to the emergency department with respiratory distress. She was admitted to the intensive care unit for non-invasive ventilation and intubated on the same day. After 10 days she was extubated. Post-extubation, the patient was unable to close her mouth, speak, or swallow, causing severe drooling. A computed tomography scan revealed a bilateral dislocation of the TMJ. An ear, nose and throat specialist successfully and easily repositioned the mandible under 5 ml of propofol, restoring normal jaw anatomy and function.</p><p><strong>Discussion: </strong>Endotracheal intubation is a predisposing factor for TMJ dislocation. Other risk factors include female sex, interincisal distance, and age. Early recognition and management are imperative, since delay scan cause difficult repositioning due to muscle spasms. Longer delays can cause long-lasting dysfunctions and pain.</p><p><strong>Conclusion: </strong>Bilateral anterior TMJ dislocation is a known but rare complication of endotracheal intubation. Swift recognition and treatment are imperative in order to prevent long-lasting anatomical and functional defects.</p><p><strong>Learning points: </strong>Bilateral temporomandibular dislocation is a rare complication after intubation.Swift repositioning of anatomical structures is important to prevent long term complications.Long-term complications of prolonged dislocation of the temporomandibular joint include persistent disfunction and/or pain.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005340"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angelo Nigro, Pasquale Santarcangelo, Antonio Bonelli, Serena Digregorio, Carmela Mazzoccoli, Giuseppe Nicoletti
{"title":"Improvement of Microangiopathy in A Systemic Sclerosis Patient Following Hysterectomy for Leiomyoma: A Potential Role of Neoplasia.","authors":"Angelo Nigro, Pasquale Santarcangelo, Antonio Bonelli, Serena Digregorio, Carmela Mazzoccoli, Giuseppe Nicoletti","doi":"10.12890/2025_005286","DOIUrl":"https://doi.org/10.12890/2025_005286","url":null,"abstract":"<p><strong>Background: </strong>Systemic sclerosis (SSc) is a complex autoimmune disease characterised by vascular alterations, immune dysregulation and fibrosis. Microangiopathy is a hallmark of SSc and can be assessed non-invasively using nailfold videocapillaroscopy (NVC).</p><p><strong>Case description: </strong>This is a case of a 50-year-old Caucasian woman with anticentromere-positive SSc, experiencing Raynaud's phenomenon and hand oedema. She met the 2013 ACR/EULAR classification criteria for SSc. Despite stable nifedipine therapy, her vasospastic episodes were only partially controlled. In March 2024, she underwent a total hysterectomy for a symptomatic uterine leiomyoma. Postoperatively, there was a marked improvement in Raynaud's phenomenon and NVC findings.</p><p><strong>Discussion: </strong>This case suggests a potential link between neoplastic processes and exacerbation of SSc-related microangiopathy. It is hypothesised that tumour-derived factors, such as inflammatory cytokines and angiogenic mediators, may contribute to endothelial dysfunction and worsen vascular impairment. The observed microvascular improvement following tumour removal supports the hypothesis that neoplasms may act as disease-modifying factors in SSc. Further studies are needed to determine whether systematic malignancy screening in selected SSc patients may help identify modifiable triggers of microangiopathy.</p><p><strong>Learning points: </strong>Observation of clinical and microvascular improvement in a systemic sclerosis patient is recommended following the removal of a uterine leiomyoma.The potential aggravating role of neoplastic processes in systemic sclerosis-associated microangiopathy.The importance of timely identification and management of neoplasms in systemic sclerosis patients to modulate disease progression.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005286"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yusuke Hirao, Bradley Fujiuchi, Kevin Benavente, Clarke Morihara, Ayumi Sakamoto, Nathan Itoga, Joseph Lee
{"title":"Acute Limb Ischemia Presenting as a Clinical Conundrum: Stroke Mimic or Aortic Dissection?","authors":"Yusuke Hirao, Bradley Fujiuchi, Kevin Benavente, Clarke Morihara, Ayumi Sakamoto, Nathan Itoga, Joseph Lee","doi":"10.12890/2025_005317","DOIUrl":"https://doi.org/10.12890/2025_005317","url":null,"abstract":"<p><p>Patients with atrial fibrillation and transthyretin amyloid cardiomyopathy (ATTR-CM) have been found to have a very high incidence of intracardiac thrombus and thromboembolic disease. Acute limb ischemia is a rare, highly morbid condition that may mimic other medical emergencies. An 88-year-old male with ATTR-CM presented with left sided hemiparesis and paraesthesia. Computed tomography scan and magnetic resonance imaging of the head was negative for stroke. Subsequent computed tomography angiography (CTA) of the chest was obtained due to an abnormal interarm blood pressure differential which was negative for acute aortic dissection but revealed simultaneous occlusions of the left axillary and common femoral arteries. These occlusions were presumed to be cardioembolic from a left atrial appendage thrombus concurrently visualized on CTA. This case highlights the importance of avoiding anchoring bias, and systematically reevaluating the differential diagnosis in cases where the initial workup is unrevealing. While an uncommon entity, simultaneous upper and lower acute limb ischemia should be considered in patients with atrial fibrillation and prothrombotic comorbidities, such as ATTR-CM.</p><p><strong>Learning points: </strong>Acute limb ischemia can mimic stroke and aortic dissection, requiring a broad differential diagnosis in patients with atrial fibrillation and transthyretin amyloid cardiomyopathy.A systematic vascular-anatomic approach helps identify embolic events when initial stroke imaging is negative.Acute ischemia may be indicated by lactic acidosis without hemodynamic instability, which should lead to additional vascular assessment.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005317"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Zinner's Syndrome: A Case Report with Typical Radiological Findings.","authors":"Mohamed Sherif El-Sharkawy, Saad Alshahrani, Mohamed A Bedewi, Kholoud J Sandougah","doi":"10.12890/2025_005284","DOIUrl":"https://doi.org/10.12890/2025_005284","url":null,"abstract":"<p><p>Zinner syndrome is a rare anomaly of the urogenital tract. The syndrome is related to delay in the embryogenesis of the ureteric buds and is associated with unilateral renal absence, cyst formation in the seminal vesicles, and ipsilateral obstruction of the ejaculatory.</p><p><strong>Learning points: </strong>Zinner syndrome is a rare syndrome with delayed embryogenesis of the ureteric buds.Three features are typically present, absence of one kidney, cyst formation of the seminal vesicles, and ejaculatory duct obstruction at the same side.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005284"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}