Alexis Fremery, Jean Pujo, Alolia Aboikoni, Karim Hamiche, Timothée Bonifay
{"title":"Body-packing, a public health issue requiring more researches.","authors":"Alexis Fremery, Jean Pujo, Alolia Aboikoni, Karim Hamiche, Timothée Bonifay","doi":"10.1097/MEJ.0000000000001095","DOIUrl":"10.1097/MEJ.0000000000001095","url":null,"abstract":"","PeriodicalId":11893,"journal":{"name":"European Journal of Emergency Medicine","volume":"31 2","pages":"158-159"},"PeriodicalIF":3.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10901218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Klara De Baerdemaeker, Alison M Dines, Thomas Nefau, Katerina Skapurova, Isabelle Giraudon, Djamel Alachaher, John R H Archer, Yedidia Bentur, Tharwat El Zahran, Jasmina Jovic-Stocic, Asaad Omary, Ait Mouhab Tahar, Hafedh Thabet, Esmeralda Thoma, Slavica Vucinic, David M Wood, Paul I Dargan
{"title":"Comparison of recreational drug presentations to the emergency department in Europe, the Middle East and Northern Africa.","authors":"Klara De Baerdemaeker, Alison M Dines, Thomas Nefau, Katerina Skapurova, Isabelle Giraudon, Djamel Alachaher, John R H Archer, Yedidia Bentur, Tharwat El Zahran, Jasmina Jovic-Stocic, Asaad Omary, Ait Mouhab Tahar, Hafedh Thabet, Esmeralda Thoma, Slavica Vucinic, David M Wood, Paul I Dargan","doi":"10.1097/MEJ.0000000000001087","DOIUrl":"10.1097/MEJ.0000000000001087","url":null,"abstract":"","PeriodicalId":11893,"journal":{"name":"European Journal of Emergency Medicine","volume":"31 2","pages":"149-151"},"PeriodicalIF":3.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zengzheng Ge, Yanxia Gao, Xin Lu, Shiyuan Yu, Mubing Qin, Chao Gong, Joseph Harold Walline, Huadong Zhu, Yi Li
{"title":"The association between levosimendan and mortality in patients with sepsis or septic shock: a systematic review and meta-analysis.","authors":"Zengzheng Ge, Yanxia Gao, Xin Lu, Shiyuan Yu, Mubing Qin, Chao Gong, Joseph Harold Walline, Huadong Zhu, Yi Li","doi":"10.1097/MEJ.0000000000001105","DOIUrl":"10.1097/MEJ.0000000000001105","url":null,"abstract":"<p><strong>Background: </strong>Levosimendan is increasingly being used in patients with sepsis or septic shock because of its potential to improve organ function and reduce mortality. We aimed to determine if levosimendan can reduce mortality in patients with sepsis or septic shock via meta-analysis.</p><p><strong>Evidence sources and study selection: </strong>We comprehensively searched the PubMed, Embase, Web of Science, and Cochrane Library databases from inception through 1 October 2022. Literature evaluating the efficacy of levosimendan in patients with sepsis or septic shock was included.</p><p><strong>Data extraction and outcome measurements: </strong>Two reviewers extracted data and assessed study quality. A meta-analysis was performed to calculate an odds ratio (OR), 95% confidence intervals (CI), and P -values for 28-day mortality (primary outcome). Secondary outcomes included changes in indexes reflecting cardiac function before and after treatment, changes in serum lactate levels in the first 24 h of treatment, and the mean SOFA score during the study period. Safety outcomes included rates of tachyarrhythmias and total adverse reactions encountered with levosimendan.</p><p><strong>Results: </strong>Eleven randomized controlled trials were identified, encompassing a total of 1044 patients. After using levosimendan, there was no statistical difference between groups for 28-day mortality (34.9% and 36.2%; OR: 0.93; 95% CI [0.72-1.2]; P = 0.57; I 2 = 0%; trial sequential analysis-adjusted CI [0.6-1.42]) and sequential organ failure assessment (SOFA) score, and more adverse reactions seemed to occur in the levosimendan group, although the septic shock patient's heart function and serum lactate level improved.</p><p><strong>Conclusion: </strong>There was no association between the use of levosimendan and 28-day mortality and SOFA scores in patients with septic shock, though there was statistically significant improvement in cardiac function and serum lactate.</p>","PeriodicalId":11893,"journal":{"name":"European Journal of Emergency Medicine","volume":" ","pages":"90-97"},"PeriodicalIF":3.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10901220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138451263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Identification of causal diseases associated with the occurrence of out-of-hospital cardiac arrest in toilets.","authors":"Yoshio Tanaka, Takahisa Kamikura, Hitoshi Owada, Hideo Inaba","doi":"10.1097/MEJ.0000000000001104","DOIUrl":"10.1097/MEJ.0000000000001104","url":null,"abstract":"","PeriodicalId":11893,"journal":{"name":"European Journal of Emergency Medicine","volume":"31 2","pages":"152-154"},"PeriodicalIF":3.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elisabeth Helen Anna Mills, Amalie Lykkemark Møller, Filip Gnesin, Nertila Zylyftari, Britta Jensen, Helle Collatz Christensen, Stig Nikolaj Blomberg, Kristian Hay Kragholm, Gunnar Gislason, Lars Køber, Thomas Gerds, Fredrik Folke, Freddy Lippert, Christian Torp-Pedersen, Mikkel Porsborg Andersen
{"title":"Association between mortality and phone-line waiting time for non-urgent medical care: a Danish registry-based cohort study.","authors":"Elisabeth Helen Anna Mills, Amalie Lykkemark Møller, Filip Gnesin, Nertila Zylyftari, Britta Jensen, Helle Collatz Christensen, Stig Nikolaj Blomberg, Kristian Hay Kragholm, Gunnar Gislason, Lars Køber, Thomas Gerds, Fredrik Folke, Freddy Lippert, Christian Torp-Pedersen, Mikkel Porsborg Andersen","doi":"10.1097/MEJ.0000000000001088","DOIUrl":"10.1097/MEJ.0000000000001088","url":null,"abstract":"<p><strong>Background and importance: </strong>Telephone calls are often patients' first healthcare service contact, outcomes associated with waiting times are unknown.</p><p><strong>Objectives: </strong>Examine the association between waiting time to answer for a medical helpline and 1- and 30-day mortality.</p><p><strong>Design, setting and participants: </strong>Registry-based cohort study using phone calls data (January 2014 to December 2018) to the Capital Region of Denmark's medical helpline. The service refers to hospital assessment/treatment, dispatches ambulances, or suggests self-care guidance.</p><p><strong>Exposure: </strong>Waiting time was grouped into the following time intervals in accordance with political service targets for waiting time in the Capital Region: <30 s, 0:30-2:59, 3-9:59, and ≥10 min.</p><p><strong>Outcome measures and analysis: </strong>The association between time intervals and 1- and 30-day mortality per call was calculated using logistic regression with strata defined by age and sex.</p><p><strong>Main results: </strong>In total, 1 244 252 callers were included, phoning 3 956 243 times, and 78% of calls waited <10 min. Among callers, 30-day mortality was 1% (16 560 deaths). For calls by females aged 85-110 30-day mortality increased with longer waiting time, particularly within the first minute: 9.6% for waiting time <30 s, 10.8% between 30 s and 1 minute and 9.1% between 1 and 2 minutes. For calls by males aged 85-110 30-day mortality was 11.1%, 12.9% and 11.1%, respectively. Additionally, among calls with a Charlson score of 2 or higher, longer waiting times were likewise associated with increased mortality. For calls by females aged 85-110 30-day mortality was 11.6% for waiting time <30 s, 12.9% between 30 s and 1 minute and 11.2% between 1 and 2 minutes. For calls by males aged 85-110 30-day mortality was 12.7%, 14.1% and 12.6%, respectively. Fewer ambulances were dispatched with longer waiting times (4%/2%) with waiting times <30 s and >10 min.</p><p><strong>Conclusion: </strong>Longer waiting times for telephone contact to a medical helpline were associated with increased 1- and 30-day mortality within the first minute, especially among elderly or more comorbid callers.</p>","PeriodicalId":11893,"journal":{"name":"European Journal of Emergency Medicine","volume":" ","pages":"127-135"},"PeriodicalIF":3.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41144166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew J Reed, Suvi Karuranga, David Kearns, Salma Alawiye, Ben Clarke, Martin Möckel, Mehmet Karamercan, Kelly Janssens, Luis Garcia-Castrillo Riesgo, Francisco Moya Torrecilla, Adela Golea, Juan Antonio Fernández Cejas, Eugenia Maria Lupan-Muresan, Edmond Zaimi, Alexander Nuernberger, Ondřej Rennét, Christian Skjaerbaek, Effie Polyzogopoulou, Judit Imecz, Paolo Groff, Rene Camilleri, Diana Cimpoesu, Miljan Jovic, Òscar Miró, Rory Anderson, Said Laribi
{"title":"Management of syncope in the Emergency Department: a European prospective cohort study (SEED).","authors":"Matthew J Reed, Suvi Karuranga, David Kearns, Salma Alawiye, Ben Clarke, Martin Möckel, Mehmet Karamercan, Kelly Janssens, Luis Garcia-Castrillo Riesgo, Francisco Moya Torrecilla, Adela Golea, Juan Antonio Fernández Cejas, Eugenia Maria Lupan-Muresan, Edmond Zaimi, Alexander Nuernberger, Ondřej Rennét, Christian Skjaerbaek, Effie Polyzogopoulou, Judit Imecz, Paolo Groff, Rene Camilleri, Diana Cimpoesu, Miljan Jovic, Òscar Miró, Rory Anderson, Said Laribi","doi":"10.1097/MEJ.0000000000001101","DOIUrl":"10.1097/MEJ.0000000000001101","url":null,"abstract":"<p><strong>Background and importance: </strong>In 2018, the European Society of Cardiology (ESC) produced syncope guidelines that for the first-time incorporated Emergency Department (ED) management. However, very little is known about the characteristics and management of this patient group across Europe.</p><p><strong>Objectives: </strong>To examine the prevalence, clinical presentation, assessment, investigation (ECG and laboratory testing), management and ESC and Canadian Syncope Risk Score (CSRS) categories of adult European ED patients presenting with transient loss of consciousness (TLOC, undifferentiated or suspected syncope).</p><p><strong>Design: </strong>Prospective, multicentre, observational cohort study.</p><p><strong>Settings and participants: </strong>Adults (≥18 years) presenting to European EDs with TLOC, either undifferentiated or thought to be of syncopal origin.</p><p><strong>Main results: </strong>Between 00:01 Monday, September 12th to 23:59 Sunday 25 September 2022, 952 patients presenting to 41 EDs in 14 European countries were enrolled from 98 301 ED presentations (n = 40 sites). Mean age (SD) was 60.7 (21.7) years and 487 participants were male (51.2%). In total, 379 (39.8%) were admitted to hospital and 573 (60.2%) were discharged. 271 (28.5%) were admitted to an observation unit first with 143 (52.8%) of these being admitted from this. 717 (75.3%) participants were high-risk according to ESC guidelines (and not suitable for discharge from ED) and 235 (24.7%) were low risk. Admission rate increased with increasing ESC high-risk factors; 1 ESC high-risk factor; n = 259 (27.2%, admission rate=34.7%), 2; 189 (19.9%; 38.6%), 3; 106 (11.1%, 54.7%, 4; 62 (6.5%, 60.4%), 5; 48 (5.0%, 67.9%, 6+; 53 (5.6%, 67.9%). Furthermore, 660 (69.3%), 250 (26.3%), 34 (3.5%) and 8 (0.8%) participants had a low, medium, high, and very high CSRS respectively with respective admission rates of 31.4%, 56.0%, 76.5% and 75.0%. Admission rates (19.3-88.9%), use of an observation/decision unit (0-100%), and percentage high-risk (64.8-88.9%) varies widely between countries.</p><p><strong>Conclusion: </strong>This European prospective cohort study reported a 1% prevalence of syncope in the ED. 4 in 10 patients are admitted to hospital although there is wide variation between country in syncope management. Three-quarters of patients have ESC high-risk characteristics with admission percentage rising with increasing ESC high-risk factors.</p>","PeriodicalId":11893,"journal":{"name":"European Journal of Emergency Medicine","volume":" ","pages":"136-146"},"PeriodicalIF":3.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138451262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Authors' reply to the comment on 'Effect of early ultrasound-guided femoral nerve block on preoperative opioid consumption in patients with hip fracture: a randomized trial'.","authors":"Camille Gerlier, Rami Mijahed, Olivier Ganansia, Gilles Chatellier","doi":"10.1097/MEJ.0000000000001116","DOIUrl":"10.1097/MEJ.0000000000001116","url":null,"abstract":"","PeriodicalId":11893,"journal":{"name":"European Journal of Emergency Medicine","volume":"31 1","pages":"78-79"},"PeriodicalIF":4.4,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138797959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metabolomics, the future of biomarkers?","authors":"Céline Occelli, Jacques Levraut, Thierry Pourcher","doi":"10.1097/MEJ.0000000000001097","DOIUrl":"10.1097/MEJ.0000000000001097","url":null,"abstract":"","PeriodicalId":11893,"journal":{"name":"European Journal of Emergency Medicine","volume":" ","pages":"7-8"},"PeriodicalIF":4.4,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138290726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pierre Catoire, Mélanie Roussel, Dorian Teissandier
{"title":"Sequence of administration of anesthetic agents during rapid sequence induction for emergency intubation: a French survey on current practices.","authors":"Pierre Catoire, Mélanie Roussel, Dorian Teissandier","doi":"10.1097/MEJ.0000000000001085","DOIUrl":"10.1097/MEJ.0000000000001085","url":null,"abstract":"","PeriodicalId":11893,"journal":{"name":"European Journal of Emergency Medicine","volume":" ","pages":"71-73"},"PeriodicalIF":4.4,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41095529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}