New Frontiers in Medicine and Medical Research Vol. 12最新文献

{"title":"Study on Evaluation of Laparoscopic Retroperitoneal Approach for Management of Various Renal Calculi","authors":".. Rudramani, V. Singh, Shesh Kumar, Anil Kumar, Shailendra Kumar, M. Singh","doi":"10.9734/bpi/nfmmr/v12/3179f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v12/3179f","url":null,"abstract":"Background: Laparoscopic surgery as an alternate to open surgery has been grown in recent years as a result of the increasing use of laparoscopy in urology together with inherent limitations of Percutaneous nephrolithotomy (PCNL). Evaluation of Laparoscopic retroperitoneal approach for management of various renal calculi must be done to get the efficacy of the procedure according to the calculus and renal morphology. \u0000Aims: The aim of present study was to evaluate laparoscopic retroperitoneal approach for management of various renal calculi. \u0000Methods: Laparoscopic retroperitoneal pyelolithotomy/nephrolithotomy was performed on 58 patients with various renal calculi patterns viz. solitary pelvic calculus, staghorn calculus, staghorn calculus with calyceal and isolated calyceal calculi. Extended pyelolithotomy, Gilvernet’s technique were used as per the need. \u0000Results: Out of the 58 cases with renal calculi, solitary renal pelvic stones (n=23; 39.7%) were most common followed by staghorn (n=11; 19% Mean size 4.40±1.17 cm) and isolated caliceal stones (n=9; 15.5% with Mean size2.21±0.25 cm) respectively. There were 15 (25.9%) cases with mixed stones (11 cases solitary renal pelvic and isolated caliceal stones and 4 cases had staghorn and isolated caliceal stones). Stone clearance was 93.3 to 100%. \u0000Conclusions: laparoscopic retroperitoneal approach is a useful modality for clearance of renal calculi of different types with minimum complications and a high success rate. However, the technique seems to have a limited role for isolated caliceal stones where direct or C-arm guided nephrolithotomy can be performed for better clearance of stones.","PeriodicalId":118581,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 12","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115583418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maxillofacial Non-Hodgkin’s Lymphoma","authors":"Santan Reddy Muthyam, P. Surekha, Charan Paul Motupalli","doi":"10.9734/bpi/nfmmr/v12/12289d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v12/12289d","url":null,"abstract":"Morbidity and mortality are the devastating outcomes of noncommunicable diseases like cancer. Incidence of cancer has been growing globally due to consumption of tobacco, alcohol, radiation, chemicals, viral infections, obesity and immunosupression. Non-Hodgkin’s Lymphoma is one of the many cancers that humans suffer with. With the increasing number of health conditions that eventually lead to immunosupression and exposure to potential risk factors, the incidence of Non-Hodgkin’s Lymphoma has increased. It’s multivariate and misleading presentation in the head and neck region is a diagnostic nightmare. Early diagnosis is possible with critical evaluation of the presenting symptoms even in disseminated cases. Fine needle aspiration cytology should be unhesitently performed that may lead the physician in opting for more confirmative histological and radiological investigations. Standard therapeutic regimens seem to work well with patients diagnosed early, however risk of relapse looms over the future. The contents of this chapter focus on the maxillofacial and head and neck manifestations of Non-Hodgkin’s Lymphoma which are not frequently encountered.","PeriodicalId":118581,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 12","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134401389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination Coagulase-nagative Staphylococcus and Antibiotic Susceptibility Patterns in Cases of Sepsis in the Neonatal Intensive Care Unit of Amiens-Picardie University Hospital (France)","authors":"A. Léké, Géraldine Amar, Bertin Elion Dzon, G. Kongolo, M. Biendo","doi":"10.9734/bpi/nfmmr/v12/11838d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v12/11838d","url":null,"abstract":"Neonatal sepsis is the most serious disease encountered in the neonatal Intensive Care Unit, and is associated with high morbidity and mortality rates. Here, we evaluated coagulase-negative Staphylococcus strains and the corresponding antibiotic susceptibility profiles in clinically suspected cases of neonatal sepsis. The objectives of the study were to determine the significance of coagulase-negative Staphylococcus strains isolated from cases of neonatal sepsis, another isolation site for coagulase-negative Staphylococcus other than blood culture and their susceptibility pattern. In a prospective study of newborns admitted to our neonatal Intensive Care Unit between January 20th, 2017, and January 20th, 2019, we analyzed all cases of sepsis with a positive blood culture, and available stool, central venous catheter, tracheobronchial, and nasopharyngeal fluid. Strains were identified using Matrix-Assisted-Laser Desorption Ionization Time of Flight Mass Spectrometry. Antimicrobial susceptibility patterns were recorded and analyzed. Of 157 premature newborns enrolled in the study, 28 (17.8%) had a coagulase-negative Staphyloccus-positive blood culture. Eighteen (64.2%) presented with early onset sepsis and 10 (35.8%) presented with late onset sepsis. Based on the gestational age at birth, there were 10 (35%) extremely preterm newborns, 12 (42.8%) very preterm newborns, and 6 (21.5%) moderately preterm newborns. The birth weight was extremely low in 13 (46.4%), very low in 9 (32.2%), low in 4 (14.2%), and normal 2 (7.2%). All coagulase-negative Staphylococcus isolates showed high levels of resistance to cefoxitin (100% of the strains), aminoglycosides (100%), fusidic acid and, ofloxacin (100%). The isolates were highly susceptible to pristinamycin (100% of the strains), vancomycin (100%) and trimethoprim-sulfamethoxazole (100%). Coagulase-negative Staphylococcus isolates constituted the most frequent cause of neonatal sepsis. The abundance of these strains may contribute to the emergence of multi-drug resistance.","PeriodicalId":118581,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 12","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134551130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Latent Class Analysis of Exposure to Childhood Trauma and Health Risks among Justice-Involved Youth: An Approach towards Gender Differences","authors":"R. Dembo, Julie M. Krupa, Jennifer Wareham, Jessica Wolff, R. DiClemente, J. Schmeidler","doi":"10.9734/bpi/nfmmr/v12/12366d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v12/12366d","url":null,"abstract":"Research indicates juvenile justice-involved youth experience increased risk of exposure to childhood trauma and health risks. Little is known about the heterogeneity in trauma and health risk experiences among delinquent youth, especially across gender. The current study uses latent class analysis to examine typologies of self-reported exposure to trauma and health risks among a sample of 435 female and 1,198 male juvenile offenders. The study objectives were to identify any subgroups of justice-involved youths with varying patterns of trauma and health risk behaviors across gender, examine the size of these trauma-health risk subgroups, and examine socio-demographic differences in the trauma-health risk latent classes. Findings suggest the presence of three groups of trauma and health risk behaviors within the gender groups. For females, the three subgroups demonstrated linear trends in increasing prevalence of trauma and health risks. For males, the three subgroups reflected a generally low-risk group, a group with high rates of marijuana use and risky sexual behaviors, and a group with high rates of depression, family problems, sexual assault victimization, and bullying. The analyses for the covariates revealed racial differences in trauma and health risks. The findings suggest gendered intervention strategies should be considered for justice-involved youth.","PeriodicalId":118581,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 12","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134312885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New-Competitive- Principal of Tumor Control by Low Dose Radiation","authors":"A. N. Shoutko, L. Yurkova, K. S. Borodulya, L. P. Ekimova","doi":"10.9734/bpi/nfmmr/v12/12422d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v12/12422d","url":null,"abstract":"In order to verify the principle of indirect control a tumor on the base of morphogenic cells distraction from it, the 114 patients with advanced ovarian carcinoma (stage III-56, stage IY-21, relapse 37), were treated with subtotal half-body (low part) irradiation at low doses (0,1 Gy x 10 for 3 weeks or 3Gy x 3 daily), and obtained data were compared with that for 190 patients (stage III-66, stage IY-25, relapse-99) received conventional local irradiation of the tumor (2 Gy x 23 daily). The surgery and chemotherapy components were equalized in both groups. The 34% and 11% of 5-years survival was obtained at low dose half body irradiation for primary and relapsed patients in comparison with conventional local radiotherapy (7% and 0%). It is concluded, that reparation /regeneration processes being provoked artificially in normal tissues of cancer host are capable to compete remotely with tumor for the morphogenic/feeding cells originated from bone marrow and circulating with the blood.","PeriodicalId":118581,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 12","volume":"216 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132523449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID Epitope is Magic","authors":"G. Pieczenik","doi":"10.9734/bpi/nfmmr/v12/12683d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v12/12683d","url":null,"abstract":"We have identified the amino acid sequences that are almost identical between the COVID 19 amino acid sequence and the Platelet Factor 4 amino acid sequence by using proprietary modifications of the NIH Blast amino acid comparison algorithm. Using molecular mimicry one can then deduce which of the many possible epitopes on the surface of the Spike protein is the true epitope which actually induces the antibody response to the COVID 19 virus and, thereby, cross reacting with the platelets. Molecular mimicry with vaccines is a known phenomenon. However, it has never been used before to identify the actual binding sequence induced by a vaccine.","PeriodicalId":118581,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 12","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132753279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report on Persistent Mullerian Duct Syndrome","authors":"Shabnam Izhar, Purnima Singh, K. Gupta","doi":"10.9734/bpi/nfmmr/v12/4099f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v12/4099f","url":null,"abstract":"Persistent Mullerian duct syndrome (PMDS) is usually an accidental finding either during orchidopexy or during routine inguinal hernia repair in male patients presenting with undescended testes. It is a rare form of internal male pseudohermaphroditism caused by defect in synthesis or action of Mullerian inhibiting factor due to which Mullerian derivatives such as uterus, fallopian tube and upper vagina are normally present in 46XY males. PMDS has an autosomal recessive inheritance. Screening of the siblings is necessary. Familiarity of operating surgeon with this disease condition would increase the chances of correctly diagnosing the case. Distinguishing PMDS from other intersex disorder is critical. A karyotyping and assessment of testicular response to chorionic gonadotropin stimulation are essential to verify both genetic sex and existence of functional testicular tissue. Here we report a 7 year old male presenting with bilateral undescended testes.","PeriodicalId":118581,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 12","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114693176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two Dimensional Ultrasonographic Analysis of Placental Maturity and Its Correlation to Gestational Age and Maternal Parameters","authors":"M. N. Mishra","doi":"10.9734/bpi/nfmmr/v12/11915d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v12/11915d","url":null,"abstract":"","PeriodicalId":118581,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 12","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129270819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Psychiatric Disorders and Their Medical-Social Consequences in Patients with Amyotrophic Lateral Sclerosis and Members of Their Families","authors":"G. Levitsky, A. S. Levitsky, Vadim M. Gilod","doi":"10.9734/bpi/nfmmr/v12/4030f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v12/4030f","url":null,"abstract":"","PeriodicalId":118581,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 12","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124810677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surrogate Motherhood-An Act of Violation or Protection of Human Rights","authors":"P. Mol, Shweta D. Gowda","doi":"10.9734/bpi/nfmmr/v12/4045f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v12/4045f","url":null,"abstract":"Introduction: Surrogacy is providing joy of parenthood to the intended couple but the irony is that to protect one woman from being called childless, surrogate takes over the responsibility of carrying her child to be stigmatized by the society. Though many issues of exploitation have received attention some like surrogacy have been overlooked. The global crisis of population and resources limitation is turning the attention of the world of reproduction towards adoption. Deep down everyone who opts for surrogacy wants to have their own DNA but how does genetic linkage tend to be more than humanity. \u0000Objectives: The objective of this commentary is to give an insight into the exploitation of surrogacy market. Another objective is to discuss how adoption is an alternative option to surrogacy.","PeriodicalId":118581,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 12","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132441450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}