Egyptian Liver Journal最新文献_第10页

Liver function test (SGPT) abnormality in 319 confirmed COVID-19 cases in Bangladesh 孟加拉国319例新冠肺炎确诊病例肝功能检测(SGPT)异常

Egyptian Liver Journal Pub Date : 2023-09-28 DOI: 10.1186/s43066-023-00283-7

Mahbuba Yesmin, Nirmol Kumar Biswas, Afroja Alam

{"title":"Liver function test (SGPT) abnormality in 319 confirmed COVID-19 cases in Bangladesh","authors":"Mahbuba Yesmin, Nirmol Kumar Biswas, Afroja Alam","doi":"10.1186/s43066-023-00283-7","DOIUrl":"https://doi.org/10.1186/s43066-023-00283-7","url":null,"abstract":"Abstract Background Deranged liver function abnormalities are well-recognized sequela of COVID-19 infection. Globally, there are studies dedicated to evaluate spectrum of liver injury by COVID-19. In this study, we have described the impact of COVID-19 on liver function tests in 319 confirmed COVID cases in Bangladesh. Our study aimed to determine the liver function alteration by COVID-19 in our population. Methods This study included all adult inpatients (> 18 years old) with laboratory-confirmed (RT-PCR) COVID-19 from March to April, 2020 in a tertiary COVID-dedicated hospital. We assessed liver function test and categorized patients according to COVID severity. This was a single-center, retrospective, observational study. Results Among 319 patients with COVID-19, 36% had normal and 64% had abnormal liver function test. Out of this, 18% had 1–2 times, 42% had 2–3 times, and 19% had > 3 times upper limit of normal SGPT during admission. Fifty-seven (18%) patients presented with mild illness, 83 (26%) with moderate, 124 (39%) patients with severe, and 54 (17%) with critical COVID-19 during admission. Significant correlation was found between severity of COVID-19 and raised SGPT level. Conclusion More than half of patients presented during admission with abnormal liver function. COVID-19 has a significant impact on liver function derangement in this population.","PeriodicalId":11620,"journal":{"name":"Egyptian Liver Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135386809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lifestyle determinants as predictor of severity of metabolic associated fatty liver disease (MAFLD) 生活方式决定因素作为代谢性脂肪肝(MAFLD)严重程度的预测因子

Egyptian Liver Journal Pub Date : 2023-09-19 DOI: 10.1186/s43066-023-00282-8

Abeer Attia, Nargis Albert Labib, Noha Essameldin Elsayed Abdelzaher, Sherief Musa, Mira Atef

{"title":"Lifestyle determinants as predictor of severity of metabolic associated fatty liver disease (MAFLD)","authors":"Abeer Attia, Nargis Albert Labib, Noha Essameldin Elsayed Abdelzaher, Sherief Musa, Mira Atef","doi":"10.1186/s43066-023-00282-8","DOIUrl":"https://doi.org/10.1186/s43066-023-00282-8","url":null,"abstract":"Abstract Background Metabolic-associated fatty liver disease (MAFLD) is a public health issue that can result in liver cirrhosis and its complications. Aim of work Assess the dietary pattern, physical activity, and sleep quality of MAFLD patients. Methods Cross-sectional study of 77 MAFLD patients being present in the outpatient clinic of Endemic Medicine Department at Cairo University Hospital. An interview questionnaire including sociodemographic, medical history, validated food frequency questionnaire (FFQ), Pittsburg Sleep Quality Index (PSQI), and international physical activity questionnaire (IPAQ) were utilized to collect data. Results Among patients, 36%, 34%, and 30% had liver steatosis grades I (mild), II (moderate), and III (severe) respectively. Waist circumference, body mass index (BMI), daily caloric and carbohydrate intake, impaired sleep quality, and low physical activity were significantly linked with steatosis grades. The independent significant predictors for MAFLD severity were waist circumference ( P = 0.011, OR 1.119), poor sleep quality ( P = 0.038, OR 3.871), habitual sleep efficiency (OR 3.402, 95%CI 1.403–8.252), daytime dysfunction (OR 2.487, 95%CI 1.374–4.501), and physical activity ( P = 0.027, OR 4.6). Conclusion Waist circumference, poor sleep quality, habitual sleep efficiency, daytime dysfunction, and low physical activity were the real marked predictors for MAFLD severity.","PeriodicalId":11620,"journal":{"name":"Egyptian Liver Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135060723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genotoxic effect of Tamiflu and Adamine on DNA content in male albino mice 达菲和阿达明对雄性白化小鼠DNA含量的遗传毒性影响

IF 0.8

Egyptian Liver Journal Pub Date : 2023-09-09 DOI: 10.1186/s43066-023-00279-3

N. Z. El-alfy, Samia M Sakr, M. Mahmoud, Heba Ahmed Omar

引用次数: 0

Hepatic involvement in childhood dengue infection 儿童登革热感染的肝脏受累

IF 0.8

Egyptian Liver Journal Pub Date : 2023-09-08 DOI: 10.1186/s43066-023-00281-9

R. Alam, M. Rukunuzzaman, K. Nahid

引用次数: 0

Hepatic function and structure in feral pigeons (Columba livia domestica) exposed to zinc oxide nanoparticles 氧化锌纳米粒子对家鸽肝脏功能和结构的影响