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Egyptian Journal of Basic and Applied Sciences最新文献

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Attenuation of streptozotocin induced high fat diet exacerbated dyslipidemia mediated hepatic and aortic injuries in male pigs by camel milk 链脲佐菌素诱导的高脂日粮的衰减加剧了骆驼奶对公猪血脂异常介导的肝脏和主动脉损伤
Egyptian Journal of Basic and Applied Sciences Pub Date : 2022-12-09 DOI: 10.1080/2314808x.2022.2155902
Hadiza Bello Rilwan, S. Adebisi, J. Timbuak, S. Oladele, A. Muhammad, Wusa Makena, Adamu Abubakar Sadeeq
{"title":"Attenuation of streptozotocin induced high fat diet exacerbated dyslipidemia mediated hepatic and aortic injuries in male pigs by camel milk","authors":"Hadiza Bello Rilwan, S. Adebisi, J. Timbuak, S. Oladele, A. Muhammad, Wusa Makena, Adamu Abubakar Sadeeq","doi":"10.1080/2314808x.2022.2155902","DOIUrl":"https://doi.org/10.1080/2314808x.2022.2155902","url":null,"abstract":"","PeriodicalId":11512,"journal":{"name":"Egyptian Journal of Basic and Applied Sciences","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73287541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of sleep deprivation and daylight restriction on the immune response to Escherichia coli-induced septicemia in Wistar rats 睡眠剥夺和日光限制对Wistar大鼠大肠杆菌败血症免疫反应的影响
Egyptian Journal of Basic and Applied Sciences Pub Date : 2022-12-09 DOI: 10.1080/2314808x.2022.2152204
A. Ige, Esther O. Agbo, Dorcas J. Brown, O. Mebude, E. Adewoye
{"title":"Effect of sleep deprivation and daylight restriction on the immune response to Escherichia coli-induced septicemia in Wistar rats","authors":"A. Ige, Esther O. Agbo, Dorcas J. Brown, O. Mebude, E. Adewoye","doi":"10.1080/2314808x.2022.2152204","DOIUrl":"https://doi.org/10.1080/2314808x.2022.2152204","url":null,"abstract":"","PeriodicalId":11512,"journal":{"name":"Egyptian Journal of Basic and Applied Sciences","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88054815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sodium-glucose transporter (SGLT2) inhibition: A potential target for treatment of type-2 Diabetes Mellitus with Natural and Synthetic compounds 钠-葡萄糖转运体(SGLT2)抑制:天然和合成化合物治疗2型糖尿病的潜在靶点
Egyptian Journal of Basic and Applied Sciences Pub Date : 2022-11-28 DOI: 10.1080/2314808x.2022.2145734
Shubham Batra, Prabhjeet Kaur Bamrah, M. Choudhary
{"title":"Sodium-glucose transporter (SGLT2) inhibition: A potential target for treatment of type-2 Diabetes Mellitus with Natural and Synthetic compounds","authors":"Shubham Batra, Prabhjeet Kaur Bamrah, M. Choudhary","doi":"10.1080/2314808x.2022.2145734","DOIUrl":"https://doi.org/10.1080/2314808x.2022.2145734","url":null,"abstract":"","PeriodicalId":11512,"journal":{"name":"Egyptian Journal of Basic and Applied Sciences","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89133044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ecological studies on the helminth parasites of catfishes Bagrus spp. (Bagridae) and Chrysichthys auratus (Claroteidae) inhabiting Damietta branch, River Nile, Egypt 生活在埃及尼罗河达米埃塔支流的鲶鱼Bagrus spp. (Bagridae)和auratus Chrysichthys (Claroteidae)寄生虫的生态学研究
Egyptian Journal of Basic and Applied Sciences Pub Date : 2022-11-25 DOI: 10.1080/2314808x.2022.2146854
Hend E. Allam, M. Mashaly, M. El-Naggar
{"title":"Ecological studies on the helminth parasites of catfishes Bagrus spp. (Bagridae) and Chrysichthys auratus (Claroteidae) inhabiting Damietta branch, River Nile, Egypt","authors":"Hend E. Allam, M. Mashaly, M. El-Naggar","doi":"10.1080/2314808x.2022.2146854","DOIUrl":"https://doi.org/10.1080/2314808x.2022.2146854","url":null,"abstract":"","PeriodicalId":11512,"journal":{"name":"Egyptian Journal of Basic and Applied Sciences","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86222844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A review of the ethnopharmacological significance of Momordica foetida Schumach. (Cucurbitaceae: Cucurbitales) 苦瓜的民族药理学意义综述。(葫芦科:Cucurbitales)
Egyptian Journal of Basic and Applied Sciences Pub Date : 2022-11-25 DOI: 10.1080/2314808x.2022.2149014
Y. Mukaila, Abdulwadud Abiodun Ajao, A. A. Ajao
{"title":"A review of the ethnopharmacological significance of Momordica foetida Schumach. (Cucurbitaceae: Cucurbitales)","authors":"Y. Mukaila, Abdulwadud Abiodun Ajao, A. A. Ajao","doi":"10.1080/2314808x.2022.2149014","DOIUrl":"https://doi.org/10.1080/2314808x.2022.2149014","url":null,"abstract":"","PeriodicalId":11512,"journal":{"name":"Egyptian Journal of Basic and Applied Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89252094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Centella asiatica L. Urban protects against cognitive dysfunction in alluminum chloride-induced neurotoxicity in rats via inhibition of acetylcholinesterase level 积雪草通过抑制乙酰胆碱酯酶水平对氯化铝诱导的神经毒性大鼠认知功能障碍的保护作用
Egyptian Journal of Basic and Applied Sciences Pub Date : 2022-10-31 DOI: 10.1080/2314808x.2022.2139114
Nur Izzaty Binti Rosli Farhani, S. M. Chiroma, T. Mohamad, M. A. Mohd Moklas
{"title":"Centella asiatica L. Urban protects against cognitive dysfunction in alluminum chloride-induced neurotoxicity in rats via inhibition of acetylcholinesterase level","authors":"Nur Izzaty Binti Rosli Farhani, S. M. Chiroma, T. Mohamad, M. A. Mohd Moklas","doi":"10.1080/2314808x.2022.2139114","DOIUrl":"https://doi.org/10.1080/2314808x.2022.2139114","url":null,"abstract":"","PeriodicalId":11512,"journal":{"name":"Egyptian Journal of Basic and Applied Sciences","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72862482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protective role of Vernonia Cinerea against the Carmoisine induced brain injury and anxiogenic effect in mice 水桐对卡莫辛所致小鼠脑损伤的保护作用及焦虑作用
Egyptian Journal of Basic and Applied Sciences Pub Date : 2022-09-27 DOI: 10.1080/2314808x.2022.2122289
N. Subramaniyan, Karthikeyan Elumalai, J. Rajangam, Narahari N Palei, Divya Talari, A. Balaji, Vijayaraj Surendran
{"title":"Protective role of Vernonia Cinerea against the Carmoisine induced brain injury and anxiogenic effect in mice","authors":"N. Subramaniyan, Karthikeyan Elumalai, J. Rajangam, Narahari N Palei, Divya Talari, A. Balaji, Vijayaraj Surendran","doi":"10.1080/2314808x.2022.2122289","DOIUrl":"https://doi.org/10.1080/2314808x.2022.2122289","url":null,"abstract":"","PeriodicalId":11512,"journal":{"name":"Egyptian Journal of Basic and Applied Sciences","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82818777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Interleukin-6 in exhaustive exercises and its correlation to bacteremia: a pilot study 力竭运动中的白细胞介素-6及其与菌血症的相关性:一项初步研究
Egyptian Journal of Basic and Applied Sciences Pub Date : 2022-09-26 DOI: 10.1080/2314808x.2022.2124343
Amr A. Elgharib, Dalia S. Khalifa, S. Magdy, Youstina M. Samir, D. Masallat
{"title":"Interleukin-6 in exhaustive exercises and its correlation to bacteremia: a pilot study","authors":"Amr A. Elgharib, Dalia S. Khalifa, S. Magdy, Youstina M. Samir, D. Masallat","doi":"10.1080/2314808x.2022.2124343","DOIUrl":"https://doi.org/10.1080/2314808x.2022.2124343","url":null,"abstract":"","PeriodicalId":11512,"journal":{"name":"Egyptian Journal of Basic and Applied Sciences","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83412285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhibitory potentials of phytocompounds from Ocimum gratissimum against anti-apoptotic BCL-2 proteins associated with cancer: an integrated computational study 芫花植物化合物对与癌症相关的抗凋亡BCL-2蛋白的抑制潜力:一项综合计算研究
Egyptian Journal of Basic and Applied Sciences Pub Date : 2022-09-20 DOI: 10.1080/2314808X.2022.2106095
Gideon A. Gyebi, Oludare M. Ogunyemi, Ibrahim M. Ibrahim, Saheed O. Afolabi, Rotimi J. Ojo, Uju D.I. Ejike, Joseph O. Adebayo
{"title":"Inhibitory potentials of phytocompounds from Ocimum gratissimum against anti-apoptotic BCL-2 proteins associated with cancer: an integrated computational study","authors":"Gideon A. Gyebi, Oludare M. Ogunyemi, Ibrahim M. Ibrahim, Saheed O. Afolabi, Rotimi J. Ojo, Uju D.I. Ejike, Joseph O. Adebayo","doi":"10.1080/2314808X.2022.2106095","DOIUrl":"https://doi.org/10.1080/2314808X.2022.2106095","url":null,"abstract":"ABSTRACT The anti-apoptotic Bcl-2 family is intrinsically involved in regulating apoptosis. Over expression of these proteins is associated with cancer. Thus, inhibitors of these proteins will enhance the development of anti-apoptotic drugs. Herein, previously reported 103 Ocimum gratissimum derived phytochemicals were screened against five anti-apoptotic BCL-2 proteins (BCL-2, MCL-1, BCL-B BCL-XL and BFL-1) to identify potential inhibitors of multiple anti-apoptotic Bcl-2 proteins, using static and dynamic docking simulations, molecular dynamics (MD) simulations, clustering and Absorption-Distribution-Metabolism-Excretion-Toxicity (ADMET) filtering analysis. Based on the minimal binding energy and a comparative reference inhibitors binding mode analysis, five lead phytochemicals (FLP) (ursolic acid, beta-sitosterol, luteolin, basilimoside and apigenin 7,4’,dimethyl ether) were identified. Ursolic acid, β-sitosterol and luteolin exhibited higher binding tendencies to the BH3 binding groove of multiple targets. Ursolic acid-Bcl-2 and luteolin-BCL-XL, complexes demonstrated structural stability in the simulated MD environment. Also, the FLP demonstrated favorable ADMET properties. Evidences from previously reported antiproliferative activities of ursolic acid, β-sitosterol and luteolin and results from this study suggest that the anti-proliferative activity of O. gratissimum may be as a result of the synergistic activities of, at least, the FLP. They are recommended for further study as natural-inhibitors against cancers defined by over expression of Bcl-2 family protein.","PeriodicalId":11512,"journal":{"name":"Egyptian Journal of Basic and Applied Sciences","volume":"39 1","pages":"588 - 608"},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77545455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hesperidin augments the health beneficial effects of alternate day fasting in male rats 橙皮苷增强隔日禁食对雄性大鼠的健康有益作用
Egyptian Journal of Basic and Applied Sciences Pub Date : 2022-09-12 DOI: 10.1080/2314808x.2022.2119517
Sukanya Bhoumik, Rashmi Kesherwani, Raushan Kumar, S. Rizvi
{"title":"Hesperidin augments the health beneficial effects of alternate day fasting in male rats","authors":"Sukanya Bhoumik, Rashmi Kesherwani, Raushan Kumar, S. Rizvi","doi":"10.1080/2314808x.2022.2119517","DOIUrl":"https://doi.org/10.1080/2314808x.2022.2119517","url":null,"abstract":"","PeriodicalId":11512,"journal":{"name":"Egyptian Journal of Basic and Applied Sciences","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82205162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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