Journal of Cardiology & Current Research最新文献_第2页

Atrioventricular dyssynchrony in patients with permanent pacemaker due to sinus node dysfunction and first-degree atrioventricular block: does the long PR syndrome exist? 窦房结功能障碍和一级房室传导阻滞导致永久性起搏器患者房室非同步化:长PR综合征存在吗?

Journal of Cardiology & Current Research Pub Date : 2022-12-27 DOI: 10.15406/jccr.2022.15.00567

Andrés Di Leoni Ferrari, E. Bartholomay, Fabio Michalsky Velho, A. Borges, Matheus Bom Fraga, Luis Manuel Ley Domingues, J. C. Pachón Mateos

引用次数: 0

Hypolipidemic trials in the elderly - a recent historic standpoint 老年人的低血脂试验——最近的历史观点

Journal of Cardiology & Current Research Pub Date : 2022-08-08 DOI: 10.15406/jccr.2022.15.00562

L. K. Junior, Naiara Pedrassi Engracia Garcia Caluz, Anita L R Saldanha, A. L. Valera Gasparoto, Bruno de Carvalho Abdala, Paulo Maurício Garcia Nosé, Dalton Fonseca Almeida, Tereza Luiza Bellincanta Fakhouri, Ana Paula Pantoja Margeotto, Tania Leme da Rocha Martinez

{"title":"Hypolipidemic trials in the elderly - a recent historic standpoint","authors":"L. K. Junior, Naiara Pedrassi Engracia Garcia Caluz, Anita L R Saldanha, A. L. Valera Gasparoto, Bruno de Carvalho Abdala, Paulo Maurício Garcia Nosé, Dalton Fonseca Almeida, Tereza Luiza Bellincanta Fakhouri, Ana Paula Pantoja Margeotto, Tania Leme da Rocha Martinez","doi":"10.15406/jccr.2022.15.00562","DOIUrl":"https://doi.org/10.15406/jccr.2022.15.00562","url":null,"abstract":"In spite of the first trials on the effect of cholesterol reduction and its beneficial impact on morbidity and mortality in the elderly many have already proven the antecipated positive results. The high risk attributable to the elderly is a guarantee for an effort in primary prevention, especially when a high level of serum cholesterol is combined with other risk factors linked to coronary artery disease. There are elements of similarity for primary prevention in the elderly over 65 years of age, compared to middle-aged patients. This consideration opened the need for scientific evidence with confirmed levels of evidence. The first studies were WOSCOPS, AFCAPS/TEXCAPS, Heart Protection Study, PROSPER, ALLHAT (Antihipertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial-Lipid Lowering Trial), REVERSAL, Health Study, ASCOT (Anglo Scandinavian Cardiac Outcomes), MIRACL, Post CABG, AVERT, ACCESS, ASSET, ATGOAL, CHALLENGE, CURVES, BELLS, ARBITER, NASDAC, PROVE-IT and DEBATE. Positive evidences were shown from the first to the last trial recalled in this historical beginning.","PeriodicalId":115064,"journal":{"name":"Journal of Cardiology & Current Research","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126972124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temporary and reversible clopidogrel, ticagrelor and prasugrel high on-treatment platelet reactivity associated to the concomitant use of morphine and fentanyl in acute coronary syndrome 暂时性和可逆性氯吡格雷、替格瑞和普拉格雷:急性冠状动脉综合征患者同时使用吗啡和芬太尼与高治疗期血小板反应性相关

Journal of Cardiology & Current Research Pub Date : 2022-08-08 DOI: 10.15406/jccr.2022.15.00563

C. Barrera-Ramı́rez, L. Pineda-Pompa, María del Rayo Pacheco Ríos, H. Ilárraza-Lomelí

{"title":"Temporary and reversible clopidogrel, ticagrelor and prasugrel high on-treatment platelet reactivity associated to the concomitant use of morphine and fentanyl in acute coronary syndrome","authors":"C. Barrera-Ramı́rez, L. Pineda-Pompa, María del Rayo Pacheco Ríos, H. Ilárraza-Lomelí","doi":"10.15406/jccr.2022.15.00563","DOIUrl":"https://doi.org/10.15406/jccr.2022.15.00563","url":null,"abstract":"Background: Recent evidence demonstrates that morphine significantly reduces absorption and delays onset of action of P2Y12-receptor inhibitors in patients with acute coronary syndrome. Case summary: 55-year-old male with inferior ST-segment–elevation myocardial infarction was treated with opioids previous and during primary angioplasty, developing temporary and reversible clopidogrel, ticagrelor and prasugrel high on-treatment platelet reactivity assessed by platelet function test. We treated with glycoprotein IIb/IIIa inhibitor as a bridge to obtain antplatelet effect by P2Y12–receptor inhibitors. Discussion: The interaction between opioids and oral P2Y12-receptor inhibitors in patients with acute coronary syndrome should be highlighted. Although morphine administration may potentially lead to detrimental clinical consequences by diminish of antiplatelet effect, its routine avoidance cannot be recommended until large scale trials be available. We suggest that if the use of morphine and other opioids is inevitable, utilization of platelet function tests to guide the antiplatelet treatment is an option.","PeriodicalId":115064,"journal":{"name":"Journal of Cardiology & Current Research","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127277841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Up is down, down is up: ectopic atrial bradycardia or junctional Rhythm? 上是下，下是上:异位房性心动过缓还是结性心律?

Journal of Cardiology & Current Research Pub Date : 2022-07-21 DOI: 10.15406/jccr.2022.15.00561

Belal Sultanzai, E. Amsterdam

引用次数: 0

Outpatient cardiac telemetry monitoring for early patient discharge: continuous focused rhythm surveillance for patients recovering outside of the hospital setting 门诊心脏遥测监测早期病人出院:持续集中节律监测病人康复院外设置

Journal of Cardiology & Current Research Pub Date : 2022-06-30 DOI: 10.15406/jccr.2022.15.00559

V. Lukyanov, Purvee Parikh, Heather Luke, Jennifer Lavelle, G. Medic, Andrew Armanious, Leigh Ann Kelly, Manish Wadhwa MD, Marie Noelle-Langan MD

引用次数: 0

A panoramic view of the myocardial infarction. etiology, pathology, and comparison with the past 心肌梗塞的全景图。病因、病理及与过去的比较

Journal of Cardiology & Current Research Pub Date : 2022-04-14 DOI: 10.15406/jccr.2022.15.00552

A. Leone

引用次数: 0

Frequency of ST-segment elevation acute myocardial infarction in patients with Type 2 Diabetes Mellitus 2型糖尿病患者st段抬高急性心肌梗死的发生频率

Journal of Cardiology & Current Research Pub Date : 2022-04-11 DOI: 10.15406/jccr.2022.15.00551

Anuradha Ghosal, S. Ghosal

{"title":"Frequency of ST-segment elevation acute myocardial infarction in patients with Type 2 Diabetes Mellitus","authors":"Anuradha Ghosal, S. Ghosal","doi":"10.15406/jccr.2022.15.00551","DOIUrl":"https://doi.org/10.15406/jccr.2022.15.00551","url":null,"abstract":"Type 2 diabetes mellitus (T2DM) is the most frequent metabolic disease encountered in India. One of the most fearful complications associated with T2DM is acute coronary syndrome (ACS). In contrast to the non-T2DM patients T2DM patients presents with atypical clinical picture and has a worse prognosis. Electrocardiogram (ECG) is a very important tool used to diagnose ACS. The ST-segment elevation (STEMI) pattern in ECG is associated with a significant and prolonged occlusion of the coronary arteries. The aim of this pilot project was to highlight the difference in ECG presentation between T2DM patients and their non-T2DM counterparts (if any). Relevant data was collected from 29 consecutive patients presenting with AMI in the cardiac care center in Nightingale hospital, Kolkata, India, after procuring their informed consent. The data was analyzed using the presence or absence of STEMI as the categorical output and its association with T2DM status as the input. The association was assessed using chi-square statistics. Jupyter notebook was used to perform the statistical analysis. The mean age of the selected population was 61.2 years with a mean blood pressure (BP) of 136/77 mm of Hg. There was a significant association between T2DM and STEMI (P=0.02), as assessed by chi-square statistics. In this small cohort from Kolkata, T2DM was significantly associated with an ECG presentation of STEMI in patients with AMI.","PeriodicalId":115064,"journal":{"name":"Journal of Cardiology & Current Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129873086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between the efficacy of tolvaptan and hemoglobin levels in acute decompensated heart failure 托伐普坦治疗急性失代偿性心力衰竭疗效与血红蛋白水平的关系

Journal of Cardiology & Current Research Pub Date : 2022-04-07 DOI: 10.15406/jccr.2022.15.00550

T. Shibata, Eiko Fukuro, Hirotake Takahashi, Y. Kayama, C. Mori, M. Kawai, M. Yoshimura

{"title":"Relationship between the efficacy of tolvaptan and hemoglobin levels in acute decompensated heart failure","authors":"T. Shibata, Eiko Fukuro, Hirotake Takahashi, Y. Kayama, C. Mori, M. Kawai, M. Yoshimura","doi":"10.15406/jccr.2022.15.00550","DOIUrl":"https://doi.org/10.15406/jccr.2022.15.00550","url":null,"abstract":"Objective: The purpose of this study is to investigate the factors that influence the effectiveness of tolvaptan treatment for acute decompensated heart failure. Methods and patients: This retrospective study included 102 patients with acute decompensated heart failure who were considered to require tolvaptan. We investigated whether tolvaptan administration was completed within 7 days or more and divided patients into two groups accordingly (responders, n = 35, non-responders, n = 67). Univariate, multivariate analysis and structural equation modeling were used to investigate the various clinical features involved in the success or failure of tolvaptan administration within 7 days. Among the investigation of various factors, changes in blood urea nitrogen, creatinine, and hemoglobin before and after tolvaptan administration were associated with the completion of tolvaptan administration. In order to proceed with further examination, we examined using a path diagram based on structural equation modeling. Results: It was found that low hemoglobin before treatment and high hemoglobin after treatment are related to the success of the completion of tolvaptan. Other factors were not related to the success of tolvaptan administration. The effectiveness of tolvaptan in pretreatment patients with low hemoglobin is especially important and hemoglobin level will be a valuable marker. Conclusion: This study showed that tolvaptan may be more effective at low hemoglobin in acute decompensated heart failure, which is generally difficult to treat. In that case, active use of tolvaptan is recommended.","PeriodicalId":115064,"journal":{"name":"Journal of Cardiology & Current Research","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116494833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intramyocardial injections of erythropoietin-analogue C.E.R.A. in ischemic cardiomyopathy: the ALSTER C.E.R.A. trial 心肌内注射促红细胞生成素类似物c.e.r.a治疗缺血性心肌病:ALSTER c.e.r.a试验

Journal of Cardiology & Current Research Pub Date : 2022-03-28 DOI: 10.15406/jccr.2022.15.00549

Christina Paitazoglou, M. Bergmann, D. Losik, E. Pokushalov, Vitaly A. Shabanov, A. Romanov

{"title":"Intramyocardial injections of erythropoietin-analogue C.E.R.A. in ischemic cardiomyopathy: the ALSTER C.E.R.A. trial","authors":"Christina Paitazoglou, M. Bergmann, D. Losik, E. Pokushalov, Vitaly A. Shabanov, A. Romanov","doi":"10.15406/jccr.2022.15.00549","DOIUrl":"https://doi.org/10.15406/jccr.2022.15.00549","url":null,"abstract":"Objectives: Erythropoietin (EPO) improved cardiac regeneration in experimental models of ischemic heart disease. A pilot trial found subcutaneously administered EPO to improve surrogate markers of left ventricular (LV) function in ischemic cardiomyopathy. This clinical study tests the feasibility and safety of the intramyocardial delivery route of a long-acting EPO-analogue (C.E.R.A.) in patients with ischemic cardiomyopathy. Methods: The ALSTER C.E.R.A. trial was a Phase II, open label, 1:1 randomized, single-center study testing intramyocardial injections of long-acting EPO analogue C.E.R.A. (C.E.R.A. NOGA: once 180 µg) using the NOGA XP system versus the subcutaneous application (C.E.R.A. SC: 30µg s.c./month for 6 months) in 59 symptomatic chronic heart failure (HF) patients with impaired LV function (ejection fraction (EF) £ 45%). Results: Follow-up up to three years with both clinical and imaging endpoints found intramyocardial delivery of C.E.R.A. to be feasible, safe and to possibly attenuate LV remodeling. Patients in the C.E.R.A. NOGA group showed stable parameter for LV end-diastolic diameter and volume (LVEDD and LVEDV), while C.E.R.A. SC patients had significant dilation of the LV (C.E.R.A. NOGA vs. SC, mean ± standard error of the mean: DLVEDD 0.02±0.1mm, p=0.8 vs. 0.3±0.09mm, p=0.0026; DLVEDV 10±15.9ml, p=0.5 vs. 34.8±11.3ml, p=0.0081; ∆EF 2.4±1.2%, p=0.045 vs. -1.6±1.1, p=0.1 respectively). NYHA class significantly improved and the hospitalization rate was numerically reduced in the C.E.R.A. NOGA group, while three-year mortality was identical. Conclusions: Intramyocardial injection of C.E.R.A. is feasible, safe and possibly attenuates LV remodeling in ischemic HF patients with LV dysfunction compared to the systemic application.","PeriodicalId":115064,"journal":{"name":"Journal of Cardiology & Current Research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127648619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diabetes: prevalence, causes, effects, physiology and risk of cardiovascular diseases 糖尿病:心血管疾病的患病率、原因、影响、生理学和风险

Journal of Cardiology & Current Research Pub Date : 2022-03-11 DOI: 10.15406/jccr.2022.15.00547

P. Gupta, D. Cieslak

引用次数: 0

Journal of Cardiology &amp; Current Research最新文献

Journal of Cardiology & Current Research最新文献