ECSOC-25最新文献

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Quantitative Analysis of Total Phenolic and Flavonoid Contents from Stachys mouretii Leaf Extracts 毛竹叶提取物中总酚和类黄酮含量的定量分析
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11802
Abdelmoughite Ouakil, Soumaya El ismaili, O. El Mahdi, A. Maurady, B. El Bali, M. Lachkar
{"title":"Quantitative Analysis of Total Phenolic and Flavonoid Contents from Stachys mouretii Leaf Extracts","authors":"Abdelmoughite Ouakil, Soumaya El ismaili, O. El Mahdi, A. Maurady, B. El Bali, M. Lachkar","doi":"10.3390/ecsoc-25-11802","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11802","url":null,"abstract":"","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83054865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis, Characterization, and Preliminary Chemosensory Ability of a Novel 2,4,5-Tri(Hetero)Arylimidazole Based on an 8-Hydroxy-Quinoline Group 基于8-羟基喹啉基团的新型2,4,5-三(杂)芳基咪唑的合成、表征和初步化学感觉能力
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11748
Odília M. P. F. Luís, Nuna L. P. Ramos, S. Costa, M. Raposo
{"title":"Synthesis, Characterization, and Preliminary Chemosensory Ability of a Novel 2,4,5-Tri(Hetero)Arylimidazole Based on an 8-Hydroxy-Quinoline Group","authors":"Odília M. P. F. Luís, Nuna L. P. Ramos, S. Costa, M. Raposo","doi":"10.3390/ecsoc-25-11748","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11748","url":null,"abstract":"","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":"34 12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77918226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Benzene-1,3,5-tricarboxylic Acid-Functionalized Cherry Gum as a Novel and Recoverable Nanocatalyst for Efficient Synthesis of 1,4-polyhydroquinoline Derivatives 苯-1,3,5-三羧酸功能化樱桃胶作为新型可回收纳米催化剂高效合成1,4-聚对苯二酚衍生物
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11717
H. Ghafuri, B. Abbasi, Nastaran Ghanbari, Yegane Rostami, Zeinab Tajik, Mahdi Akhgari
{"title":"Benzene-1,3,5-tricarboxylic Acid-Functionalized Cherry Gum as a Novel and Recoverable Nanocatalyst for Efficient Synthesis of 1,4-polyhydroquinoline Derivatives","authors":"H. Ghafuri, B. Abbasi, Nastaran Ghanbari, Yegane Rostami, Zeinab Tajik, Mahdi Akhgari","doi":"10.3390/ecsoc-25-11717","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11717","url":null,"abstract":"","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72923487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Thiophene-Based Dicyanovinyl as an Anion Chemosensor 噻吩基双氰乙烯基作为阴离子化学传感器
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11769
J. P. Castro, M. Raposo, S. Costa
{"title":"A Thiophene-Based Dicyanovinyl as an Anion Chemosensor","authors":"J. P. Castro, M. Raposo, S. Costa","doi":"10.3390/ecsoc-25-11769","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11769","url":null,"abstract":": In recent years, push–pull dicyanovinyl derivatives have been reported for several optical applications, including as fluorescent probes for cyanide ion detection. In the presence of cyanide ions, this type of compound exhibits an ICT mechanism associated with the addition of the cyanide ion to the β position of the dicyanovinyl group, due to the strong electron-withdrawing effect of the cyano groups. These structural changes caused by the addition reaction are accompanied by changes in the probe’s absorption and emission. In this work, we report a thiophene-based dicyanovinyl derivative and its prospective application as an anion chemosensor. The photophysical characterization was carried out in acetonitrile and aqueous acetonitrile solutions. Preliminary sensing assays in the presence of various anions of biological, medicinal, and environmental relevance were conducted, and the interaction with CN − was further explored through spectrophotometric titrations.","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84235627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Study of Diels–Alder Reactions of Purpurogallin Tetraacetate with Various Dienophiles 四乙酸紫癜没食子素与多种亲二酚反应的研究
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11707
Salima Dib, B. Mostefa-Kara, D. Villemin, N. Bar
{"title":"Study of Diels–Alder Reactions of Purpurogallin Tetraacetate with Various Dienophiles","authors":"Salima Dib, B. Mostefa-Kara, D. Villemin, N. Bar","doi":"10.3390/ecsoc-25-11707","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11707","url":null,"abstract":": Purpurogallin or (6 E ,8 Z )-2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one is a benzotropo-lone possessing a dienic system and is known to inhibit TLR1/TLR2 activation pathway. We have recently described the easy green synthesis of purpurogallin from pyrogallol catalyzed by a copper complex or by vegetable oxidases. The purpurogalline was acetylated and the tetraacetate derivative thus obtained was engaged in a Diels Alder reaction with various dienophiles (benzoquinone, maleic anhydride, ethylmaleimide, phenylmaleimide, etc.). The results obtained will be presented and discussed.","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75866780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design, Synthesis and Structural Characterization of a Novel Asymmetric Hydrazone-Thiosemicarbazone Ligand with the Aim of Obtaining Interesting Metallosupramolecular Architectures 一种新型不对称腙-硫代氨基脲配体的设计、合成和结构表征,旨在获得有趣的金属超分子结构
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11738
Sandra Fernández-Fariña, Isabel Velo-Heleno, M. Martínez‐Calvo, Ana M. González-Noya, Rosa Pedrido
{"title":"Design, Synthesis and Structural Characterization of a Novel Asymmetric Hydrazone-Thiosemicarbazone Ligand with the Aim of Obtaining Interesting Metallosupramolecular Architectures","authors":"Sandra Fernández-Fariña, Isabel Velo-Heleno, M. Martínez‐Calvo, Ana M. González-Noya, Rosa Pedrido","doi":"10.3390/ecsoc-25-11738","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11738","url":null,"abstract":"","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86536590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytotoxicity Studies of Eugenol Amino Alcohols Derivatives 丁香酚氨基醇衍生物的细胞毒性研究
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11689
C. Teixeira, Nuno F S Pinto, David M. Pereira, R. Pereira, M. J. Fernandes, E. M. Castanheira, A. Fortes, M. S. Gonçalves
{"title":"Cytotoxicity Studies of Eugenol Amino Alcohols Derivatives","authors":"C. Teixeira, Nuno F S Pinto, David M. Pereira, R. Pereira, M. J. Fernandes, E. M. Castanheira, A. Fortes, M. S. Gonçalves","doi":"10.3390/ecsoc-25-11689","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11689","url":null,"abstract":": Eugenol is a phenylpropanoid displaying a wide range of biological activities. In this study, the cytotoxic activity of various β -amino alcohols derivatives from eugenol was evaluated in AGS (gastric cancer) and A549 (lung cancer) cell lines. The results show that some structural modi-fications resulted in enhanced cytotoxic activity towards cancer cells. In addition, the activation of caspase-3 and hence apoptosis induced by these molecules, was also explored. Considering the ob-tained results, some structure/activity relationships can be drawn, which may guide future structural improvements for anticancer agents.","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89738434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
In-Silico Studies toward the Improvement of the Antibacterial Activity of Pristinamycin IIB 提高普替那霉素IIB抗菌活性的硅片研究
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11703
Assia Chebieb, C. Ziani-Chérif, Khadidja Bellifa
{"title":"In-Silico Studies toward the Improvement of the Antibacterial Activity of Pristinamycin IIB","authors":"Assia Chebieb, C. Ziani-Chérif, Khadidja Bellifa","doi":"10.3390/ecsoc-25-11703","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11703","url":null,"abstract":": Pristinamycin IIB (PIIB) is a potent antibiotic with limited use, due to some structural problems and also due to the bacterial resistance exhibited toward the antibiotic. A thorough study led to the design of novel analogues of PIIB, based on the introduction of a difluorostatone moiety. Herein, we describe the initial in silico studies toward these novel analogues using ADMET modeling of predictive models in order to compute the physicochemistry and estimate the pharmacokinetics, drug-likeness and medicinal chemistry friendliness of these newly designed analogues.","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89745922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of At-Bridge Nitro Groups on the Photophysics and Chiroptics of helicoBODIPYs: A Step Forward towards the Development of New Chiroptical Sensors 桥上硝基对螺旋obodipys光物理和光热学的影响:新型光热传感器的研究进展
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11701
César Ray, Carolina Díaz-Norambuena, C. Schad, Florencio Moreno, A. R. Agarrabeitia, M. Ortiz, T. Arbeloa, J. Bañuelos, B. L. Maroto, S. D. L. Moya
{"title":"Influence of At-Bridge Nitro Groups on the Photophysics and Chiroptics of helicoBODIPYs: A Step Forward towards the Development of New Chiroptical Sensors","authors":"César Ray, Carolina Díaz-Norambuena, C. Schad, Florencio Moreno, A. R. Agarrabeitia, M. Ortiz, T. Arbeloa, J. Bañuelos, B. L. Maroto, S. D. L. Moya","doi":"10.3390/ecsoc-25-11701","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11701","url":null,"abstract":": A new helicoBODIPY (bisBODIPY with helical chirality) with nitro groups at the chiral bridge has been synthesized as a model to study the influence of the at-bridge substitution on the photophysics and chiroptics of the helicoBODIPY. This preliminary study reveals that at-bridge substitution can be a strategy for the development of chiroptical sensors based on helicoBODIPYs.","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85628804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and Biological Evaluation of Some Substituted Benzimidazole Derivatives 取代苯并咪唑衍生物的合成及生物学评价
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11764
S. Patil, P. Bhatt, H. Suryawanshi, J. Patil, Rajesh Chaudhari
{"title":"Synthesis and Biological Evaluation of Some Substituted Benzimidazole Derivatives","authors":"S. Patil, P. Bhatt, H. Suryawanshi, J. Patil, Rajesh Chaudhari","doi":"10.3390/ecsoc-25-11764","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11764","url":null,"abstract":"","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84368566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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