Diving and hyperbaric medicine最新文献_第7页

IF 0.8 4区医学

Diving and hyperbaric medicine Pub Date : 2024-03-31 DOI: 10.28920/dhm54.1.74-75

Andrew Tabner, Graham Johnson, Philip Bryson

引用次数: 0

Effect of hyperbaric oxygen treatment on ischaemia-reperfusion injury in rats detorsioned after experimental ovarian torsion. 高压氧治疗对实验性卵巢扭转后脱体大鼠缺血再灌注损伤的影响

IF 0.8 4区医学

Diving and hyperbaric medicine Pub Date : 2024-03-31 DOI: 10.28920/dhm54.1.16-22

Eralp Bulutlar, Ali Yilmaz, Gizem Berfin Uluutku Bulutlar, Yavuz Aslan, Hale Nur Bozdağ, Zafer Küçükodaci

{"title":"Effect of hyperbaric oxygen treatment on ischaemia-reperfusion injury in rats detorsioned after experimental ovarian torsion.","authors":"Eralp Bulutlar, Ali Yilmaz, Gizem Berfin Uluutku Bulutlar, Yavuz Aslan, Hale Nur Bozdağ, Zafer Küçükodaci","doi":"10.28920/dhm54.1.16-22","DOIUrl":"10.28920/dhm54.1.16-22","url":null,"abstract":"Introduction: This study aimed to investigate whether hyperbaric oxygen treatment (HBOT) could ameliorate ischaemia-reperfusion injury in a rat model of ovarian torsion-detorsion.Methods: Twenty-seven rats were divided among four groups: surgical sham rats (S) (n = 6) underwent identical anaesthesia and surgical incisions to other groups (n = 7 per group) but with no ovary intervention; torsion rats (T) underwent laparotomy, ovarian torsion, relaparotomy and sacrifice after three hours; torsion and detorsion rats (T/DT) underwent laparotomy, ovarian torsion (three hours), relaparotomy and detorsion, and sacrifice after one week; torsion, detorsion, hyperbaric oxygen rats (T/DT/HBOT) underwent laparotomy, ovarian torsion, relaparotomy and detorsion, and sacrifice after one week during which HBOT was provided 21 times (100% oxygen at 600 kPa for 50 min). In all groups blood collection for markers of oxidative stress or related responses, and ovary collection for histology were performed after sacrifice.Results: When the T/DT, and T/DT/HBOT groups were compared, 8-hydroxy-2'-deoxyguanosine (a marker of oxidative damage to DNA) and malondialdehyde (a product of lipid peroxidation) levels were lower in the T/DT/HBOT group. Anti-Mullerian hormone levels were higher in the T/DT/HBOT group compared to the T/DT group. In addition, oedema, vascular occlusion, neutrophilic infiltration and follicular cell damage were less in the T/DT/HBOT group than in the T/DT group.Conclusions: When biochemical and histopathological findings were evaluated together, HBOT appeared reduce ovarian ischaemia / reperfusion injury in this rat model of ovarian torsion-detorsion.","PeriodicalId":11296,"journal":{"name":"Diving and hyperbaric medicine","volume":"54 1","pages":"16-22"},"PeriodicalIF":0.8,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11227960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140174143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk assessment of SWEN21 a suggested new dive table for the Swedish armed forces: bubble grades by ultrasonography. 瑞典武装部队新潜水表 SWEN21 的风险评估：超声波检查气泡等级。

IF 0.8 4区医学

Diving and hyperbaric medicine Pub Date : 2023-12-20 DOI: 10.28920/dhm53.4.299-305

Carl Hjelte, Oscar Plogmark, Mårten Silvanius, Magnus Ekström, Oskar Frånberg

{"title":"Risk assessment of SWEN21 a suggested new dive table for the Swedish armed forces: bubble grades by ultrasonography.","authors":"Carl Hjelte, Oscar Plogmark, Mårten Silvanius, Magnus Ekström, Oskar Frånberg","doi":"10.28920/dhm53.4.299-305","DOIUrl":"10.28920/dhm53.4.299-305","url":null,"abstract":"Introduction: To develop the diving capacity in the Swedish armed forces the current air decompression tables are under revision. A new decompression table named SWEN21 has been created to have a projected risk level of 1% for decompression sickness (DCS) at the no stop limits. The aim of this study was to evaluate the safety of SWEN21 through the measurement of venous gas emboli (VGE) in a dive series.Methods: A total 154 dives were conducted by 47 divers in a hyperbaric wet chamber. As a proxy for DCS risk serial VGE measurements by echocardiography were conducted and graded according to the Eftedal-Brubakk scale. Measurements were done every 15 minutes for approximately 2 hours after each dive. Peak VGE grades for the different dive profiles were used in a Bayesian approach correlating VGE grade and risk of DCS. Symptoms of DCS were continually monitored.Results: The median (interquartile range) peak VGE grade after limb flexion for a majority of the time-depth combinations, and of SWEN21 as a whole, was 3 (3-4) with the exception of two decompression profiles which resulted in a grade of 3.5 (3-4) and 4 (4-4) respectively. The estimated risk of DCS in the Bayesian model varied between 4.7-11.1%. Three dives (2%) resulted in DCS. All symptoms resolved with hyperbaric oxygen treatment.Conclusions: This evaluation of the SWEN21 decompression table, using bubble formation measured with echocardiography, suggests that the risk of DCS may be higher than the projected 1%.","PeriodicalId":11296,"journal":{"name":"Diving and hyperbaric medicine","volume":"53 4","pages":"299-305"},"PeriodicalIF":0.8,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10944666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138801018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measuring whole body inert gas wash-out. 测量全身惰性气体冲洗。

IF 0.8 4区医学

Diving and hyperbaric medicine Pub Date : 2023-12-20 DOI: 10.28920/dhm53.4.321-326

Oscar Plogmark, Mårten Silvanius, Max Olsson, Carl Hjelte, Magnus Ekström, Oskar Frånberg

{"title":"Measuring whole body inert gas wash-out.","authors":"Oscar Plogmark, Mårten Silvanius, Max Olsson, Carl Hjelte, Magnus Ekström, Oskar Frånberg","doi":"10.28920/dhm53.4.321-326","DOIUrl":"10.28920/dhm53.4.321-326","url":null,"abstract":"Introduction: Quantifying inert gas wash-out is crucial to understanding the pathophysiology of decompression sickness. In this study, we developed a portable closed-circuit device for measuring inert gas wash-out and validated its precision and accuracy both with and without human subjects.Methods: We developed an exhalate monitor with sensors for volume, temperature, water vapor and oxygen. Inert gas volume was extrapolated from these inputs using the ideal gas law. The device's ability to detect volume differences while connected to a breathing machine was analysed by injecting a given gas volume eight times. One hundred and seventy-two coupled before-and-after measurements were then compared with a paired t-test. Drift in measured inert gas volume during unlabored breathing was evaluated in three subjects at rest using multilevel linear regression. A quasi-experimental cross-over study with the same subjects was conducted to evaluate the device's ability to detect inert gas changes in relation to diving interventions and simulate power.Results: The difference between the injected volume (1,996 ml) and the device's measured volume (1,986 ml) was -10 ml. The 95% confidence interval (CI) for the measured volume was 1,969 to 2,003 ml. Mean drift during a 43 min period of unlaboured breathing was -19 ml, (95% CI, -37 to -1). Our power simulation, based on a cross-over study design, determined a sample size of two subjects to detect a true mean difference of total inert gas wash-out volume of 100 ml.Conclusions: We present a portable device with acceptable precision and accuracy to measure inert gas wash-out differences that may be physiologically relevant in the pathophysiology of decompression sickness.","PeriodicalId":11296,"journal":{"name":"Diving and hyperbaric medicine","volume":"53 4","pages":"321-326"},"PeriodicalIF":0.8,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10944667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138801113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary oxygen toxicity breath markers after heliox diving to 81 metres. 螺旋氧潜水至 81 米后的肺氧毒性呼吸标记。

IF 0.8 4区医学

Diving and hyperbaric medicine Pub Date : 2023-12-20 DOI: 10.28920/dhm53.4.340-344

Feiko Jm de Jong, Paul Brinkman, Thijs T Wingelaar, Pieter-Jan Am van Ooij, Robert A van Hulst

{"title":"Pulmonary oxygen toxicity breath markers after heliox diving to 81 metres.","authors":"Feiko Jm de Jong, Paul Brinkman, Thijs T Wingelaar, Pieter-Jan Am van Ooij, Robert A van Hulst","doi":"10.28920/dhm53.4.340-344","DOIUrl":"10.28920/dhm53.4.340-344","url":null,"abstract":"Pulmonary oxygen toxicity (POT), an adverse reaction to an elevated partial pressure of oxygen in the lungs, can develop as a result of prolonged hyperbaric hyperoxic conditions. Initially starting with tracheal discomfort, it results in pulmonary symptoms and ultimately lung fibrosis. Previous studies identified several volatile organic compounds (VOCs) in exhaled breath indicative of POT after various wet and dry hyperbaric hypoxic exposures, predominantly in laboratory settings. This study examined VOCs after exposures to 81 metres of seawater by three navy divers during operational heliox diving. Univariate testing did not yield significant results. However, targeted multivariate analysis of POT-associated VOCs identified significant (P = 0.004) changes of dodecane, tetradecane, octane, methylcyclohexane, and butyl acetate during the 4 h post-dive sampling period. No airway symptoms or discomfort were reported. This study demonstrates that breath sampling can be performed in the field, and VOCs indicative of oxygen toxicity are exhaled without clinical symptoms of POT, strengthening the belief that POT develops on a subclinical-to-symptomatic spectrum. However, this study was performed during an actual diving operation and therefore various confounders were introduced, which were excluded in previous laboratory studies. Future studies could focus on optimising sampling protocols for field use to ensure uniformity and reproducibility, and on establishing dose-response relationships.","PeriodicalId":11296,"journal":{"name":"Diving and hyperbaric medicine","volume":"53 4","pages":"340-344"},"PeriodicalIF":0.8,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10944665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138801016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing the EMMA capnograph with sidestream capnography and arterial carbon dioxide pressure at 284 kPa. 比较 EMMA 毛细血管通气记录仪与侧流毛细血管通气记录仪以及 284 千帕的动脉二氧化碳压力。

IF 0.9 4区医学

Diving and hyperbaric medicine Pub Date : 2023-12-20 DOI: 10.28920/dhm53.4.327-332

Xavier Ce Vrijdag, Hanna van Waart, Chris Sames, Jamie W Sleigh, Simon J Mitchell

{"title":"Comparing the EMMA capnograph with sidestream capnography and arterial carbon dioxide pressure at 284 kPa.","authors":"Xavier Ce Vrijdag, Hanna van Waart, Chris Sames, Jamie W Sleigh, Simon J Mitchell","doi":"10.28920/dhm53.4.327-332","DOIUrl":"10.28920/dhm53.4.327-332","url":null,"abstract":"Introduction: Capnography aids assessment of the adequacy of mechanical patient ventilation. Physical and physiological changes in hyperbaric environments create ventilation challenges which make end-tidal carbon dioxide (ETCO2) measurement particularly important. However, obtaining accurate capnography in hyperbaric environments is widely considered difficult. This study investigated the EMMA capnograph for hyperbaric use.Methods: We compared the EMMA capnograph to sidestream capnography and the gold standard arterial carbon dioxide blood gas analysis in a hyperbaric chamber. In 12 resting subjects breathing air at 284 kPa, we recorded ETCO2 readings simultaneously derived from the EMMA and sidestream capnographs during two series of five breaths (total 24 measurements). An arterial blood gas sample was also taken simultaneously in five participants.Results: Across all measurements there was a difference of about 0.1 kPa between the EMMA and sidestream capnographs indicating a very slight over-estimation of ETCO2 by the EMMA capnograph, but fundamentally good agreement between the two end-tidal measurement methods. Compared to arterial blood gas pressure the non-significant difference was about 0.3 and 0.4 kPa for the EMMA and sidestream capnographs respectively.Conclusions: In this study, the EMMA capnograph performed equally to the sidestream capnograph when compared directly, and both capnography measures gave clinically acceptable estimates of arterial PCO2.","PeriodicalId":11296,"journal":{"name":"Diving and hyperbaric medicine","volume":"53 4","pages":"327-332"},"PeriodicalIF":0.9,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10735710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138801089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperbaric oxygen treatment in delayed post-hypoxic encephalopathy following inhalation of liquefied petroleum gas: a case report. 吸入液化石油气后迟发性缺氧后脑病的高压氧治疗：病例报告。

IF 0.8 4区医学

Diving and hyperbaric medicine Pub Date : 2023-12-20 DOI: 10.28920/dhm53.4.351-355

Kubra Canarslan Demir, Burak Turgut, Kubra Ozgok Kangal, Taylan Zaman, Kemal Şimşek

{"title":"Hyperbaric oxygen treatment in delayed post-hypoxic encephalopathy following inhalation of liquefied petroleum gas: a case report.","authors":"Kubra Canarslan Demir, Burak Turgut, Kubra Ozgok Kangal, Taylan Zaman, Kemal Şimşek","doi":"10.28920/dhm53.4.351-355","DOIUrl":"10.28920/dhm53.4.351-355","url":null,"abstract":"Delayed post-hypoxic encephalopathy can occur after an episode of anoxia or hypoxia. Symptoms include apathy, confusion, and neurological deficits. We describe a 47-year-old male patient who inhaled gas from a kitchen stove liquid petroleum gas cylinder. He was diagnosed with hypoxic ischaemic encephalopathy 12 hours after his emergency department admission. He received six sessions of hyperbaric oxygen treatment (HBOT) and was discharged in a healthy state after six days. Fifteen days later, he experienced weakness, loss of appetite, forgetfulness, depression, balance problems, and inability to perform self-care. One week later, he developed urinary and fecal incontinence and was diagnosed with post-hypoxic encephalopathy. After 45 days from the onset of symptoms, he was referred to the Underwater and Hyperbaric Medicine Department for HBOT. The patient exhibited poor self-care and slow speech rate, as well as ataxic gait and dysdiadochokinesia. Hyperbaric oxygen was administered for twenty-four sessions, which significantly improved the patient's neurological status with only hypoesthesia in the left hand remaining at the end of treatment. Hyperbaric oxygen has been reported as successful in treating some cases of delayed neurological sequelae following CO intoxication. It is possible that HBO therapy may also be effective in delayed post-hypoxic encephalopathy from other causes. This may be achieved through mechanisms such as transfer of functional mitochondria to the injury site, remyelination of damaged neurons, angiogenesis and neurogenesis, production of anti-inflammatory cytokines, and balancing of inflammatory and anti-inflammatory cytokines.","PeriodicalId":11296,"journal":{"name":"Diving and hyperbaric medicine","volume":"53 4","pages":"351-355"},"PeriodicalIF":0.8,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10944663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138801099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

University of Auckland Postgraduate Diploma in Diving and Hyperbaric Medicine. 奥克兰大学潜水和高压氧医学研究生文凭。

IF 0.8 4区医学

Diving and hyperbaric medicine Pub Date : 2023-12-20 DOI: 10.28920/dhm53.4.360

Michael Davis

引用次数: 0

Full-face snorkel masks increase the incidence of hypoxaemia and hypercapnia during simulated snorkelling compared to conventional snorkels. 与传统呼吸管相比，全脸呼吸管面罩会增加模拟呼吸过程中低氧血症和高碳酸血症的发生率。

IF 0.9 4区医学

Diving and hyperbaric medicine Pub Date : 2023-12-20 DOI: 10.28920/dhm53.4.313-320

Janneke Grundemann, Xavier Ce Vrijdag, Nicole Ye Wong, Nicholas Gant, Simon J Mitchell, Hanna van Waart

{"title":"Full-face snorkel masks increase the incidence of hypoxaemia and hypercapnia during simulated snorkelling compared to conventional snorkels.","authors":"Janneke Grundemann, Xavier Ce Vrijdag, Nicole Ye Wong, Nicholas Gant, Simon J Mitchell, Hanna van Waart","doi":"10.28920/dhm53.4.313-320","DOIUrl":"10.28920/dhm53.4.313-320","url":null,"abstract":"Introduction: Air flow in full-face snorkel masks (FFSMs) should be unidirectional to prevent rebreathing of exhaled air. This study evaluated rebreathing and its consequences when using FFSMs compared to a conventional snorkel.Methods: In a dry environment 20 participants wore three types of snorkel equipment in random order: Subea Easybreath FFSM; QingSong 180-degree panoramic FFSM; and a Beuchat Spy conventional snorkel (with nose clip), in three conditions: rest in a chair; light; and moderate intensity exercise on a cycle ergometer. Peripheral oxygen saturation, partial pressure of carbon dioxide (PCO2) and oxygen (PO2) in the end tidal gas and FFSM eye-pockets, respiratory rate, minute ventilation, were measured continuously. Experiments were discontinued if oxygen saturation dropped below 85%, or if end-tidal CO2 exceeded 7.0 kPa.Results: Experimental runs with the FFSMs had to be discontinued more often after exceeding 7.0 kPa end-tidal CO2 compared to a conventional snorkel e.g., 18/40 (45%) versus 4/20 (20%) during light intensity exercise, and 9/22 (41%) versus 3/16 (19%) during moderate intensity exercise. Thirteen participants exhibited peripheral oxygen saturations below 95% (nine using FFSMs and four using the conventional snorkel) and five fell below 90% (four using FFSMs and one using the conventional snorkel). The PCO2 and PO2 in the eye-pockets of the FFSMs fluctuated and were significantly higher and lower respectively than in inspired gas, which indicated rebreathing in all FFSM wearers.Conclusions: Use of FFSMs may result in rebreathing due to non-unidirectional flow, leading to hypercapnia and hypoxaemia.","PeriodicalId":11296,"journal":{"name":"Diving and hyperbaric medicine","volume":"53 4","pages":"313-320"},"PeriodicalIF":0.9,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10735670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138801096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hypoxic loss of consciousness in air diving: two cases of mixtures made hypoxic by oxidation of the scuba diving cylinder. 空气潜水中的缺氧性意识丧失：两个因潜水气瓶氧化而导致混合物缺氧的案例。

IF 0.8 4区医学

Diving and hyperbaric medicine Pub Date : 2023-12-20 DOI: 10.28920/dhm53.4.356-359

Arnaud Druelle, Lucille Daubresse, Jean U Mullot, Hélène Streit, Pierre Louge

引用次数: 0