Dermatologica最新文献

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Follicular impetigo as presenting sign of systemic lupus erythematosus. 滤泡性脓疱疮是系统性红斑狼疮的表现。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247802
T Lazzari, A Parodi, A Rebora
{"title":"Follicular impetigo as presenting sign of systemic lupus erythematosus.","authors":"T Lazzari,&nbsp;A Parodi,&nbsp;A Rebora","doi":"10.1159/000247802","DOIUrl":"https://doi.org/10.1159/000247802","url":null,"abstract":"<p><p>A patient with an unusual form of follicular impetigo, who later developed classical systemic lupus erythematosus (SLE) is described. When she had pyoderma, direct immunofluorescence and serology already suggested a connective tissue disease. Pyoderma could have been the presenting manifestation of SLE.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"182 4","pages":"233-4"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247802","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13044278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Metastatic squamous cell carcinoma resembling angiosarcoma complicating dystrophic epidermolysis bullosa. 类似血管肉瘤的转移性鳞状细胞癌并发营养不良大疱性表皮松解症。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247803
J A McGrath, O M Schofield, B J Mayou, P H McKee, R A Eady
{"title":"Metastatic squamous cell carcinoma resembling angiosarcoma complicating dystrophic epidermolysis bullosa.","authors":"J A McGrath,&nbsp;O M Schofield,&nbsp;B J Mayou,&nbsp;P H McKee,&nbsp;R A Eady","doi":"10.1159/000247803","DOIUrl":"https://doi.org/10.1159/000247803","url":null,"abstract":"<p><p>We report a patient with generalized recessive dystrophic epidermolysis bullosa (RDEB) who developed 3 squamous cell carcinomas. The tumours appeared simultaneously at acral sites on both upper limbs and were poorly differentiated. Despite surgery and radiotherapy the patient died from metastatic disease within 6 months of presentation. This case highlights many of the typical features of this complication of RDEB, including the overall poor prognosis. Of particular interest was the histology of one of the tumours which caused diagnostic difficulties: haematoxylin and eosin staining suggested an angiosarcomatous pathology, but the use of immunocytochemistry proved that the tumour was a squamous cell carcinoma in origin.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"182 4","pages":"235-8"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247803","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13044279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 28
Loose anagen hair in a child with Noonan's syndrome. 患有努南氏综合症的儿童毛发蓬松。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247806
A Tosti, C Misciali, P Borrello, P A Fanti, F Bardazzi, A Patrizi
{"title":"Loose anagen hair in a child with Noonan's syndrome.","authors":"A Tosti,&nbsp;C Misciali,&nbsp;P Borrello,&nbsp;P A Fanti,&nbsp;F Bardazzi,&nbsp;A Patrizi","doi":"10.1159/000247806","DOIUrl":"https://doi.org/10.1159/000247806","url":null,"abstract":"<p><p>We report on a 4 1/2-year-old girl affected by loose anagen hair and Noonan's syndrome. The girl had short, blond, easily pluckable hair that had never been cut. The trichogram showed an absolute prevalence of abnormally shaped anagen bulbs lacking inner and outer root sheaths. A scalp biopsy evidenced a marked cleft formation between fragmented inner root sheaths and irregularly shaped hair shafts.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"182 4","pages":"247-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247806","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13044281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 23
Porokeratosis and chromosomal abnormalities. 角化孔症和染色体异常。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247742
G Orecchia, L Perfetti, S Scappaticci
{"title":"Porokeratosis and chromosomal abnormalities.","authors":"G Orecchia,&nbsp;L Perfetti,&nbsp;S Scappaticci","doi":"10.1159/000247742","DOIUrl":"https://doi.org/10.1159/000247742","url":null,"abstract":"","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"182 1","pages":"65-6"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247742","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13170875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Topical retinoic acid does not alter the vasoconstrictive properties of topical corticosteroids in humans. 局部维甲酸不会改变人类局部皮质类固醇的血管收缩特性。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247755
C Schmied, J H Saurat
{"title":"Topical retinoic acid does not alter the vasoconstrictive properties of topical corticosteroids in humans.","authors":"C Schmied,&nbsp;J H Saurat","doi":"10.1159/000247755","DOIUrl":"https://doi.org/10.1159/000247755","url":null,"abstract":"<p><p>Dermo-epidermal atrophy is one of the main side effects of long-term treatment with topical corticosteroids. Retinoic acid may prevent and even reverse these effects in animals. Extension of this concept to therapy in humans implies that several studies have been performed; among others, it has to be established that treatment with topical retinoic acid does not interfere with the anti-inflammatory action of topical corticosteroids. The present study on the cutaneous vasoconstriction test comprised two different double-blind approaches: (i) vasoconstriction tests with betamethasone dipropionate (Diprolene) and clobetasone butyrate (Emovate) were carried out on skin that had previously been treated for 10 days with retinoic acid 0.01, 0.025 or 0.05% (or excipient); (ii) vasoconstriction tests with a combination of triamcinolone acetonide 0.1% and retinoic acid 0.025% were compared with triamcinolone acetonide 0.1% alone. Pretreatment for 10 days with retinoic acid did not alter the vasoconstriction induced by corticosteroids: no decrease or increase in the vasoconstriction score was observed, whether the skin had been previously treated with retinoic acid or with excipient. The vasoconstriction scores obtained with a combination of retinoic acid and triamcinolone acetonide were identical with those obtained with the steroid alone. This study indicates that retinoic acid does not inhibit the vasoconstriction induced by topical corticosteroids and suggests that the anti-inflammatory effect of the latter should be maintained in association with retinoic acid.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"182 2","pages":"107-11"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247755","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13206620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Hair casts. 头发投。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247760
A Van Staey, E Suys, L Derumeaux, L De Raeve, A De Coninck, D Roseeuw
{"title":"Hair casts.","authors":"A Van Staey,&nbsp;E Suys,&nbsp;L Derumeaux,&nbsp;L De Raeve,&nbsp;A De Coninck,&nbsp;D Roseeuw","doi":"10.1159/000247760","DOIUrl":"https://doi.org/10.1159/000247760","url":null,"abstract":"<p><p>Hair casts are small cylindrical structures, encircling individual scalp hairs but easily movable along the involved hair shafts. This hair disorder of unknown pathogenesis is only rarely mentioned in the dermatologic literature. We report the case of a 5-year-old girl, who has been treated during 2 years for pediculosis capitis. The literature about hair casts is reviewed.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"182 2","pages":"124-7"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247760","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13206623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pili torti and onychodysplasia. Report of a previously undescribed hidrotic ectodermal dysplasia. 绒毛和甲关节发育不良。报告先前未描述的汗液性外胚层发育不良。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247779
P. Calzavara-Pinton, A. Carlino, A. Benetti, G. Panfilis
{"title":"Pili torti and onychodysplasia. Report of a previously undescribed hidrotic ectodermal dysplasia.","authors":"P. Calzavara-Pinton, A. Carlino, A. Benetti, G. Panfilis","doi":"10.1159/000247779","DOIUrl":"https://doi.org/10.1159/000247779","url":null,"abstract":"Ectodermal dysplasias are a large and heterogeneous groups of clinically and genetically distinct syndromes. We studied a family suffering from dystrophies of the distal part of the nails and trichodysplasia. Scalp, beard, pubic and axillary hair were broken off leaving a stubble 1-10 mm in length. Eyebrows, eyelashes and body hair were completely absent. Serum levels of copper and plasma levels of amino acids were within the normal range. Inheritance was autosomal recessive. Previous reports of ectodermal dysplasias and other complex syndromes with pili torti are reviewed.","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"1 1","pages":"184-7"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80893920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 38
CD4+ memory T cells in peripheral blood are not decreased in patients with atopic dermatitis. 特应性皮炎患者外周血CD4+记忆T细胞不降低。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247751
J Burgard, V Mielke, G Leimenstoll, W Sterry
{"title":"CD4+ memory T cells in peripheral blood are not decreased in patients with atopic dermatitis.","authors":"J Burgard,&nbsp;V Mielke,&nbsp;G Leimenstoll,&nbsp;W Sterry","doi":"10.1159/000247751","DOIUrl":"https://doi.org/10.1159/000247751","url":null,"abstract":"<p><p>Atopic dermatitis (AD) is a severe and chronic eczematous skin disease, to which increased IgE levels and imbalances of CD4+ T cells are related. CD4+ T cells, however, are heterogeneous and include at least two subpopulations being designated as CD4+ naive and memory T cells. They represent sequential maturational stages (naive into memory) in CD4+ T cell development differing in function and phenotype. Of these two subpopulations the CD4+ memory T cell compartment is a potent producer of gamma-interferon which suppresses IgE synthesis in B cells. Therefore, we speculated whether an inborn maturation defect of CD4+ memory T cells causes the increased IgE production in AD. In patients with AD and age- and sex-matched controls (both n = 10) we analyzed the distribution of both subpopulations in peripheral blood by two-color flow cytometry using monoclonal antibodies against the CD4, CD45RA and CD29 antigen. We provide evidence that the numerical values of CD4+ memory T cells and CD4+ naive T cells are equivalent in both groups. This supports the view that functional disturbances of lymphocytes or lymphocyte subsets are responsible for IgE excess and the pathogenesis of AD.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"182 2","pages":"85-8"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247751","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12840728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Localized bullous eruptions caused by extravasation of commonly used intravenous infusion fluids. 常用静脉输液外渗引起的局部大疱性脓肿。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247735
B J Robijns, W M de Wit, N J Bosma, W A van Vloten
{"title":"Localized bullous eruptions caused by extravasation of commonly used intravenous infusion fluids.","authors":"B J Robijns,&nbsp;W M de Wit,&nbsp;N J Bosma,&nbsp;W A van Vloten","doi":"10.1159/000247735","DOIUrl":"https://doi.org/10.1159/000247735","url":null,"abstract":"<p><p>Extravasation is a frequent complication associated with intravenous infusions. Two case histories are reported in which blister formation is one of the most striking features after the accident. The infusion fluids are no vesicants but commonly used intravenous infusion fluids. The factors on which the eventual extent of tissue damage depends are discussed, as are the mechanisms by which these factors cause damage on a cellular level. Experienced personnel, selecting the right location for the infusion, flexible catheters and frequent inspection of the infusion are important factors to prevent extravasation. If extravasation is suspected, the infusion should be stopped, aspiration should be performed, the extremity involved should be elevated, wet compresses should be applied and exact documentation of the accident is required.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"182 1","pages":"39-42"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247735","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13168903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Atypical neutrophilic dermatosis on the upper extremity affected by postmastectomy lymphedema: report of 2 cases. 乳房切除术后淋巴水肿并发上肢非典型中性粒细胞性皮肤病2例报告。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247677
T Demitsu, T Tadaki
{"title":"Atypical neutrophilic dermatosis on the upper extremity affected by postmastectomy lymphedema: report of 2 cases.","authors":"T Demitsu,&nbsp;T Tadaki","doi":"10.1159/000247677","DOIUrl":"https://doi.org/10.1159/000247677","url":null,"abstract":"<p><p>We describe 2 female patients, both with a history of radical mastectomy for breast cancer, in whom several indurated erythematous plaques developed on the upper extremity affected by postmastectomy lymphedema. There were no general symptoms or leukocytosis. Histopathological examination showed a dense neutrophilic infiltrate without a feature of vasculitis in the dermis and subcutis. Dramatic therapeutic response was observed to treatment with potassium iodide. These findings resemble Sweet's syndrome, but such cases have not been previously reported. Possible pathogenic mechanisms for these unique cutaneous eruptions are discussed.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"183 3","pages":"230-3"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247677","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12906231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 48
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