Dermatologica最新文献_第2页

Pemphigus erythematosus with suprabasilar acantholysis and lichenoid tissue reaction or a combination of pemphigus vulgaris and lupus erythematosus: a new entity? 伴有基底上棘层溶解和地衣样组织反应的红斑天疱疮还是寻常型天疱疮和红斑狼疮的合并:一种新的实体?

Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247673

M Megahed, G Goerz, P Kind, G Plewig

引用次数: 5

Do cutaneous coryneform bacteria produce short-chain fatty acids in vitro? 皮肤棒状细菌在体外产生短链脂肪酸吗?

Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247733

A Lukacs, H C Korting, G Ruckdeschel, W Ehret

引用次数: 10

Liver iron overload and desferrioxamine treatment of porphyria cutanea tarda. 肝铁超载加去铁胺治疗迟发性皮肤卟啉症。

Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247732

E Rocchi, M Cassanelli, A Borghi, F Paolillo, M Pradelli, S Pellizzardi, A Vezzosi, E Gallo, M Baccarani Contri, E Ventura

{"title":"Liver iron overload and desferrioxamine treatment of porphyria cutanea tarda.","authors":"E Rocchi, M Cassanelli, A Borghi, F Paolillo, M Pradelli, S Pellizzardi, A Vezzosi, E Gallo, M Baccarani Contri, E Ventura","doi":"10.1159/000247732","DOIUrl":"https://doi.org/10.1159/000247732","url":null,"abstract":"The aim of this paper is to evaluate invasive and non-invasive indices of iron store and compare the effectiveness of different ferrodepletive protocols in 150 patients with porphyria cutanea tarda (PCT). Iron removal was performed either by intensive phlebotomy (22 cases) or slow subcutaneous and high intravenous doses of desferrioxamine (18 and 5 cases, respectively), and several laboratory parameters were studied; among these, oligo-elements and urinary porphyrins (detected by HPLC) were taken into account before and after the treatments. Serum iron, transferrin saturation, ferritin (RIA) and nuclear magnetic resonance results were compared with invasive findings in order to detect the metal deposition in liver tissue (atomic absorption concentration, optic or electron-microscopic detection). Liver iron overload was observed in 95% of cases. Full normalization of the disease took place by all the treatments, even if it required slightly more time in the phlebotomy group. We may conclude that ferrodepletive treatments are highly effective in PCT and, considering the fact that siderosis and liver damage always accompany the disease, these treatments are proposed as first choice in such cases.","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247732","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13168901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Vulvitis granulomatosa and anoperineitis granulomatosa. 外阴肉芽肿和肛门肉芽肿。

Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247761

H Hackel, A A Hartmann, G Burg

引用次数: 16

Nodular cutaneous mucinosis--an unusual multiple type of euthyreotic focal mucinosis. 结节性皮肤黏液病——一种罕见的多发性甲状腺增生局灶性黏液病。

Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247643

B. Schneider, D. Hohl, U. Schnyder

引用次数: 16

In vivo biophysical characterization of skin physiological differences in races. 人种皮肤生理差异的体内生物物理特征。

Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247752

E Berardesca, J de Rigal, J L Leveque, H I Maibach

引用次数: 0

The immunogold-silver staining procedure in the study of freshly suspended Langerhans cells at the transmission electron microscopic level. 透射电镜下研究新鲜悬浮朗格汉斯细胞免疫金-银染色方法。

Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247799

G C Manara, C Ferrari, C Torresani, G De Panfilis

引用次数: 3

Clinical comparison of cefuroxime axetil, cephalexin and cefadroxil in the treatment of patients with primary infections of the skin or skin structures. 头孢呋辛酯、头孢氨苄和头孢氨苄酯治疗原发性皮肤或皮肤结构感染的临床比较。

Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247629

W M Gooch, L Kaminester, G W Cole, R Binder, M R Morman, J M Swinehart, M Wisniewski, H M Yilmaz, J J Collins

{"title":"Clinical comparison of cefuroxime axetil, cephalexin and cefadroxil in the treatment of patients with primary infections of the skin or skin structures.","authors":"W M Gooch, L Kaminester, G W Cole, R Binder, M R Morman, J M Swinehart, M Wisniewski, H M Yilmaz, J J Collins","doi":"10.1159/000247629","DOIUrl":"https://doi.org/10.1159/000247629","url":null,"abstract":"This study was designed to compare the clinical and bacteriological efficacy of three oral cephalosporins, cefuroxime axetil, cephalexin and cefadroxil, in the treatment of patients with mild to moderate infections of the skin or skin structures. A total of 330 patients were enrolled at 10 centers and were randomly assigned to receive cefuroxime axetil 250 mg (n = 107), cephalexin 500 mg (n = 111) or cefadroxil 500 mg (n = 112), twice daily for 10 days. Patients were assessed for their clinical and bacteriological responses once during treatment (3-5 days) and twice after treatment (1-3 and 10-14 days). A total of 353 bacterial isolates were obtained: Staphylococcus aureus (41%), Staphylococcus epidermidis (33%) and Streptococcus pyogenes (5%). A satisfactory clinical outcome (cure or improvement) was achieved in 97% (89/92), 89% (80/90) and 94% (82/87) of the clinically evaluable patients treated with cefuroxime axetil, cephalexin or cefadroxil, respectively (p = 0.047, cefuroxime axetil vs. cephalexin). With respect to the eradication of the bacterial pathogens, a satisfactory outcome (cure or presumed cure) was obtained in 96% (69/72), 85% (60/71) and 93% (63/68) of bacteriologically evaluable patients treated with cefuroxime axetil, cephalexin and cefadroxil, respectively (p = 0.026, cefuroxime axetil vs. cephalexin). All three study drugs were well tolerated, with adverse events affecting the gastrointestinal system most commonly reported. There were no significant differences between treatment groups in the incidence of drug-related adverse events.","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247629","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12932031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Spontaneous monitoring of adverse reactions to drugs by Italian dermatologists: a pilot study. Gruppo Italiano Studi Epidemiologici in Dermatologia. 由意大利皮肤科医生自发监测药物不良反应:一项试点研究。意大利皮肤病学流行病学研究。

Dermatologica Pub Date : 1991-01-01

引用次数: 0

A case of hepatitis related to etretinate therapy and hepatitis B vaccine. 与依退酯治疗及乙肝疫苗有关的肝炎1例。

Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247758

C Green, T Lakshmipathi

引用次数: 0