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[Effectiveness of combination treatment with H1-(Tavegyl) and H2-antagonists (Altramet) in chronic/chronically-recurrent urticaria]. [H1-(Tavegyl)和h2 -拮抗剂(Altramet)联合治疗慢性/慢性复发性荨麻疹的有效性]。
Dermatologische Monatschrift Pub Date : 1990-01-01
G Wozel, E M Sahre, J Barth
{"title":"[Effectiveness of combination treatment with H1-(Tavegyl) and H2-antagonists (Altramet) in chronic/chronically-recurrent urticaria].","authors":"G Wozel,&nbsp;E M Sahre,&nbsp;J Barth","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Histamine H1 receptor antagonists are a mainstay in the management of chronic/chronic recurrent urticaria (c./c.r.U.). Since experimental studies have confirmed the presence of cutaneous H2 receptors partially conflicting results have been reported on the use of H2 antagonists in c./c.r.U. 20 patients with c./c.r.U. of idiopathic type were treated with cimetidine plus clemastine or placebo plus clemastine in a double-blind crossover study. Before this treatment traditional H1 antagonists alone failed to show any satisfying therapeutic effect. The results reveal that combined therapy is statistically more effective than corresponding H1 antagonists alone (P = 0.001). The addition of cimetidine is proposed in patients with c./c.r.U. if conventional therapy has been tried and proven ineffective.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 11","pages":"653-9"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13239144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of tar and dithranol on fibrinolysis in treatment of psoriasis]. [焦油和二甘醇对银屑病纤溶治疗的影响]。
Dermatologische Monatschrift Pub Date : 1990-01-01
P Arenberger, L Buchtová
{"title":"[Effect of tar and dithranol on fibrinolysis in treatment of psoriasis].","authors":"P Arenberger,&nbsp;L Buchtová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>There are well known side effects of drugs for topical use due to systemic resorption. In the present study, however, 36 psoriasis blood sera were examined before and fourteen days after the coal tar and dithranol (anthralin, cignolin) therapy onset to determine D and E fibrinogen fragments. These serum levels were compared with those in 36 blood donors. The higher levels in psoriatics and their causes are being discussed.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 11","pages":"699-700"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13239149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The rabbit ear model as comedogenic test. 3. Histologic and enzyme histochemical studies of the follicle and sebaceous gland epithelium]. 以兔耳模型作致痘试验。3.毛囊和皮脂腺上皮的组织学和酶组织化学研究。
Dermatologische Monatschrift Pub Date : 1990-01-01
R Zimmermann
{"title":"[The rabbit ear model as comedogenic test. 3. Histologic and enzyme histochemical studies of the follicle and sebaceous gland epithelium].","authors":"R Zimmermann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A strongly comedogenic mineral oil induced histologically and enzyme-histochemically detectable changes in the follicles and sebaceous gland ducts in the skin of rabbit ears. These correlate to findings concerning acne vulgaris in humans. The rabbit ear model thus appears to be suitable for experimental studies into acne vulgaris.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 1","pages":"55-61"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13292321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Changes in the functional surface markers of lymphocytes in short-term culture]. 短期培养淋巴细胞功能表面标志物的变化。
Dermatologische Monatschrift Pub Date : 1990-01-01
R Laub, W Wohlrab
{"title":"[Changes in the functional surface markers of lymphocytes in short-term culture].","authors":"R Laub,&nbsp;W Wohlrab","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cultured human lymphocytes are a suitable system for testing pharmacological, allergological, and toxicological effects of substances in vitro. For such investigations, the knowledge about the behaviour of the test system under standardized conditions is an important prerequisite. In the 72 h short-time-culture, no changes in T-lymphocytes were found. Small decreases occurred in the subpopulations of cytotoxical/suppressor cells, and inducer/helper cells, respectively. Number of cells expressing class II antigens of the main histocompatibility complex decreases, too (to 62%). Tritium thymidine incorporation rates inform about DNA-synthesis.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 2-3","pages":"129-32"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13512966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Therapeutic use of splenopentin (DA SP-5) in patients with psoriasis arthropathica]. [脾喷汀(DA SP-5)在银屑病关节病患者中的治疗应用]。
Dermatologische Monatschrift Pub Date : 1990-01-01
J Greiner, M Miehe, H Weber, A Stoimenov, N Sönnichsen, W Diezel
{"title":"[Therapeutic use of splenopentin (DA SP-5) in patients with psoriasis arthropathica].","authors":"J Greiner,&nbsp;M Miehe,&nbsp;H Weber,&nbsp;A Stoimenov,&nbsp;N Sönnichsen,&nbsp;W Diezel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>8 patients with confirmed psoriatic arthritis were treated with splenopentin for 12 months. A relief of joint pain could be detected under this treatment both after 6 weeks (improvement of the Ritchie-indices: 44%) and after 12 months (improvement: 28%). In contrast to this, X-ray investigations show a worsening of the disease after 12 months. Therefore we conclude that splenopentin alone is not a sufficient therapeutic drug in patients suffering from psoriatic arthritis.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 2-3","pages":"157-62"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13512969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[AIDS--personal responsibility and social problem]. [艾滋病——个人责任与社会问题]。
Dermatologische Monatschrift Pub Date : 1990-01-01
N Sönnichsen
{"title":"[AIDS--personal responsibility and social problem].","authors":"N Sönnichsen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 4","pages":"215-8"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13523906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cytokeratins--survey of incidence in normal and diseased skin. II. Cytokeratin expression in diseased skin]. 细胞角蛋白——正常和病变皮肤的发病率调查。2病变皮肤细胞角蛋白表达[j]。
Dermatologische Monatschrift Pub Date : 1990-01-01
I Heidenbluth, K Conrad
{"title":"[Cytokeratins--survey of incidence in normal and diseased skin. II. Cytokeratin expression in diseased skin].","authors":"I Heidenbluth,&nbsp;K Conrad","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The distribution patterns of cytokeratins demonstrated by different authors in benign and malignant tumours of the skin are presented and the resulting possibilities for histological differentiation are discussed. The monoclonal antibody A53-B/A2 made in GDR may be useful in the diagnosis of Merkel cell tumours or of the extramammary Morbus Paget. -For different dermatoses, especially some disease with abnormal types of keratinization, the expressed polypeptides are described.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 2-3","pages":"87-95"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12859744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Light protective effect of tannic acid 10% SR]. [单宁酸10% SR的光防护作用]。
Dermatologische Monatschrift Pub Date : 1990-01-01
G Würbach, H Kewitsch, K Godenschweger
{"title":"[Light protective effect of tannic acid 10% SR].","authors":"G Würbach,&nbsp;H Kewitsch,&nbsp;K Godenschweger","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 10","pages":"633-4"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13234441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The mouse erythrocyte binding receptor is expressed on human keratinocytes. 小鼠红细胞结合受体在人角质形成细胞上表达。
Dermatologische Monatschrift Pub Date : 1990-01-01
A Dobozy, J Hunyadi, B Bozoky, E Monostori, I Andó, A S Kenderessy, A Tiba
{"title":"The mouse erythrocyte binding receptor is expressed on human keratinocytes.","authors":"A Dobozy,&nbsp;J Hunyadi,&nbsp;B Bozoky,&nbsp;E Monostori,&nbsp;I Andó,&nbsp;A S Kenderessy,&nbsp;A Tiba","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Immunocytes and different types of epidermal cells share cell surface antigen characteristics e.g. keratinocytes react specifically with the Leu 11 (CD16) monoclonal antibody and they express MHC class II and OKM5 (CD36) antigens after gamma-interferon stimulation. The present study provides evidence that a subpopulation of human keratinocytes most probably at a certain stage of differentiation, possesses the mouse erythrocyte binding receptor the marker of a human B lymphocyte subset. This finding is a further evidence for the relationship between the epidermis and the immune system.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 10","pages":"615-21"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13139374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of pepstatin A on Candida albicans infection in the mouse]. [胃抑素A对小鼠白色念珠菌感染的影响]。
Dermatologische Monatschrift Pub Date : 1990-01-01
C Zotter, U F Haustein, C Schönborn, H D Grimmecke, H Wand
{"title":"[Effect of pepstatin A on Candida albicans infection in the mouse].","authors":"C Zotter,&nbsp;U F Haustein,&nbsp;C Schönborn,&nbsp;H D Grimmecke,&nbsp;H Wand","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The intravenous injection of 10(6) to 10(7) Candida albicans cells revealed to be a reliable model in mice produce infections of the kidney. Higher germ contents could be yielded in the kidney after the application of protease positive Candida-strains as compared to protease negative ones. Additionally, after the infection with protease positive strains a proteolytic activity could be found in the kidney homogenates in vitro on casein plates. The modulation of this Candida infection by pepstatin A, an inhibitor of extracellular yeast proteases in vitro, has also been studied in the same mice model in vivo. The growth rate of Candida albicans has been measured in the left kidney by counting the germ content as described by Haenel. Infections could be reduced after single doses of 120 micrograms pepstatin A contrary to 60 micrograms pepstatin A. The same was with three doses of 180 micrograms at 24 h intervals. This protease inhibitory effect could also be found in kidney homogenates in vitro on casein plates and lasted until 48 h post injection. On the basis of this positive effects on the Candida infection in mice pepstatin A should be considered as an adjuvans in the therapy of severe yeast infections.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 2-3","pages":"189-98"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13348647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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