Prevention and Research最新文献_第2页

Sindrome delle apnee ostruttive del sonno 睡眠呼吸暂停障碍综合症

Prevention and Research Pub Date : 1900-01-01 DOI: 10.7362/2240-2594.060.2012

M. Fabiani

引用次数: 7

Electromagnetic fields and autoimmune diseases 电磁场和自身免疫性疾病

Prevention and Research Pub Date : 1900-01-01 DOI: 10.11138/PER/2014.3.2.079

P. Boscolo

{"title":"Electromagnetic fields and autoimmune diseases","authors":"P. Boscolo","doi":"10.11138/PER/2014.3.2.079","DOIUrl":"https://doi.org/10.11138/PER/2014.3.2.079","url":null,"abstract":"Introduction: experimental studies demonstrated that electromagnetic fields (EMFs) modify ion calcium fluxes in the membranes of blood mononuclear cells and induce changes in metabolism and surface marker expression. There is also evidence of autoimmune diseases in subjects with genetic predisposition, following exposure to physical, chemical or biological noxious agents or perception of stressful situations. The aim of this systematic review is to evaluate the effects of electromagnetic fields (EMFs) on onset and progression of autoimmune diseases. Materials and Methods: all papers published in scientific journal from 1979 to 2013 were examined for inclusion in the systematic review. The research was conducted using the following key-words: electromagnetic fields, immune response, autoimmunity, Systemic Lupus Erythematosus. 37 studies were included in this article. Results: there is clear evidence that exposure to EMFs produced by radiotelevision broadcasting stations, radars, or electricity induces changes (within the physiological range) in number and percentage of circulating immune cells as well as in the immune response. Experimental studies on rats demonstrated that exposure to electricity induces metabolic effects similar to those of stress. Women resident near high power lines showed reduced melatonin production as in workers performing stressful night shifts. Employees with prolonged conversation time on mobile phone showed lower levels of serum TSH (index of increased thyroid metabolism) as in situations of stress. Discussion: it is demonstrated that there is absorption of energy in organisms exposed to EMFs; the effects of the EMFs (more elevated on the immune and nervous systems) are similar to those induced by stress stimulations. We suggest that the adaptation of tissues to the EMFs, in genetically predisposed subjects, may stimulate the onset and progression of autoimmune diseases.","PeriodicalId":109386,"journal":{"name":"Prevention and Research","volume":"407 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121894629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New anathemas: conscientious objection and freedom to access drugs in emergency contraception 新的诅咒:出于良心拒服兵役和获得紧急避孕药物的自由

Prevention and Research Pub Date : 1900-01-01 DOI: 10.11138/PR/2012.1.1.001

Costantino Cialella

引用次数: 1

Case report of an occupational electrocution fatality: histopathological, medicolegal, work safety and insurance implications 职业性触电死亡病例报告:组织病理学、医学、工作安全和保险意义

Prevention and Research Pub Date : 1900-01-01 DOI: 10.11138/PER/2017.6.2.012

M. Sammicheli

引用次数: 1

Enterobacter cloacae ventriculitis successfully treated with cerebrospinal system irrigation and intraventricular colistin, preliminary report 脑脊髓系统灌洗和脑室内粘菌素治疗阴沟肠杆菌脑室炎成功，初步报告

Prevention and Research Pub Date : 1900-01-01 DOI: 10.11138/PER/2017.6.2.031

C. Pizzoni

引用次数: 0

Recent advances in pathophysiology of biliary tree: influence of sex hormones in cholangiocyte growth 胆道病理生理研究进展:性激素对胆管细胞生长的影响

Prevention and Research Pub Date : 1900-01-01 DOI: 10.11138/PR/2012.1.2.073

R. Mancinelli

{"title":"Recent advances in pathophysiology of biliary tree: influence of sex hormones in cholangiocyte growth","authors":"R. Mancinelli","doi":"10.11138/PR/2012.1.2.073","DOIUrl":"https://doi.org/10.11138/PR/2012.1.2.073","url":null,"abstract":"Cholangiocytes are epithelial cells that line the biliary tree (1). The intrahepatic biliary tree is characterized by interconnected ducts which starts with canals of Hering, continues into intrahepatic ducts of increasing diameter to end at the level of the extrahepatic bile ducts (2). These cells play a key role in the ductal secretion of water and bicarbonate during the process of bile formation. These cells are also the target in several chronic cholestatic liver diseases (termed cholangiopathies), including primary sclerosing cholangitis (PSC), primary biliary cirrhosis (PBC), polycystic liver disease (PCLD) and cholangiocarcinoma (CCA) (3, 4). During these conditions, the balance between proliferation/loss of cholangiocytes is lost with critical effect on the maintenance of biliary functions and intrahepatic bile ductal mass (3, 5, 6). A typical feature that occurs under specific experimental conditions, such as common bile duct ligation (BDL) (Fig.1). After BDL, there is biliary hyperplasia and secretin stimulated choleresis (a functional marker of cholangiocyte growth) (5). Cholangiocyte growth/apoptosis is regulated by several factors, including growth factors, cytokines, gastrointestinal and sex hormones, such as estrogens, prolactin, follicle-stimulating hormone (FSH), testosterone and progesterone (3, 7, 8, 9). The purpose of this review is to summarize the recent findings on the effects of sex hormones in cholangiocyte pathophysiology. To clarify the mechanisms of action of these substances will provide new potential strategies for the management of chronic liver diseases.","PeriodicalId":109386,"journal":{"name":"Prevention and Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130379966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Medicolegal considerations on the concept of inability according to the law no 222/84 (INPS) and the law no 118/71 (Civil Invalidity): similarities, differences and operational practices in the medicolegal evaluation of oncological diseases 根据第222/84号法律(INPS)和第118/71号法律(民事无效)对无能概念的医学法律考虑:肿瘤疾病医学法律评估中的异同和操作做法

Prevention and Research Pub Date : 1900-01-01 DOI: 10.11138/PER/2016.5.4.140

M. Sammicheli

引用次数: 0

THE PRIMARY AND SECONDARY ENDOMETRIOSIS WITHIN ABDOMINAL WALL 腹壁内原发性和继发性子宫内膜异位症

Prevention and Research Pub Date : 1900-01-01 DOI: 10.11138/PR/2013.2.1.001

R. Capoano, M. C. Tesori, E. Mastroluca, G. Lacroce, K. Llange, E. Gianfrancesco, C. Donello, Federica Lombardo

引用次数: 0

Perceived stress and hepatic parameters 感知压力和肝脏参数

Prevention and Research Pub Date : 1900-01-01 DOI: 10.11138/PER/2016.5.4.118

F. Tomei