{"title":"Interactions between mitochondria and cytoplasm in isolated hepatocytes.","authors":"M N Berry, J W Phillips, A R Grivell","doi":"10.1016/b978-0-12-152833-1.50023-x","DOIUrl":"https://doi.org/10.1016/b978-0-12-152833-1.50023-x","url":null,"abstract":"<p><p>Results from a wide variety of metabolic studies have provided indirect support for conclusions derived from enzymological approaches that the enzymes of the so-called soluble cytoplasm (and the mitochondrial matrix) exist within the cell and function in the form of multienzyme complexes and that metabolite channeling takes place between the enzymes of each complex. Our studies support the possibility that the enzymes of glycolysis in liver are segregated from those of gluconeogenesis. Thus, the segregation and aggregation of Krebs cycle enzymes in the mitochondrial matrix, elucidated by Paul Srere, may be an example of a general pattern of enzyme organization pertaining to all metabolic pathways.</p>","PeriodicalId":10933,"journal":{"name":"Current topics in cellular regulation","volume":"33 ","pages":"309-28"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12668507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R W Estabrook, J M Trant, P A Mathew, J I Mason, M R Waterman
{"title":"\"Designer membranes\": construction of a cell containing multiple membrane-bound cytochromes P450.","authors":"R W Estabrook, J M Trant, P A Mathew, J I Mason, M R Waterman","doi":"10.1016/b978-0-12-152833-1.50029-0","DOIUrl":"https://doi.org/10.1016/b978-0-12-152833-1.50029-0","url":null,"abstract":"","PeriodicalId":10933,"journal":{"name":"Current topics in cellular regulation","volume":"33 ","pages":"419-31"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12668511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interactions of glycolytic enzymes with cellular membranes.","authors":"K Uyeda","doi":"10.1016/b978-0-12-152833-1.50008-3","DOIUrl":"https://doi.org/10.1016/b978-0-12-152833-1.50008-3","url":null,"abstract":"","PeriodicalId":10933,"journal":{"name":"Current topics in cellular regulation","volume":"33 ","pages":"31-46"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12559011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Signal transduction by the colony-stimulating factor-1 receptor; comparison to other receptor tyrosine kinases.","authors":"A W Lee","doi":"10.1016/b978-0-12-152832-4.50005-7","DOIUrl":"https://doi.org/10.1016/b978-0-12-152832-4.50005-7","url":null,"abstract":"","PeriodicalId":10933,"journal":{"name":"Current topics in cellular regulation","volume":"32 ","pages":"73-181"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12491800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nucleoside diphosphokinase: a functional link between intermediary metabolism and nucleic acid synthesis.","authors":"N B Ray, C K Mathews","doi":"10.1016/b978-0-12-152833-1.50025-3","DOIUrl":"https://doi.org/10.1016/b978-0-12-152833-1.50025-3","url":null,"abstract":"","PeriodicalId":10933,"journal":{"name":"Current topics in cellular regulation","volume":"33 ","pages":"343-57"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12496977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B Sumegi, Z Porpaczy, M T McCammon, A D Sherry, C R Malloy, P A Srere
{"title":"Regulatory consequences of organization of citric acid cycle enzymes.","authors":"B Sumegi, Z Porpaczy, M T McCammon, A D Sherry, C R Malloy, P A Srere","doi":"10.1016/b978-0-12-152833-1.50019-8","DOIUrl":"https://doi.org/10.1016/b978-0-12-152833-1.50019-8","url":null,"abstract":"","PeriodicalId":10933,"journal":{"name":"Current topics in cellular regulation","volume":"33 ","pages":"249-60"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12668504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The molecular physiology of citrate.","authors":"P A Srere","doi":"10.1016/b978-0-12-152833-1.50020-4","DOIUrl":"https://doi.org/10.1016/b978-0-12-152833-1.50020-4","url":null,"abstract":"","PeriodicalId":10933,"journal":{"name":"Current topics in cellular regulation","volume":"33 ","pages":"261-75"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12559010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of glycolytic enzymes with the cytoskeleton.","authors":"H R Knull, J L Walsh","doi":"10.1016/b978-0-12-152833-1.50007-1","DOIUrl":"https://doi.org/10.1016/b978-0-12-152833-1.50007-1","url":null,"abstract":"<p><p>The diverse physical associations of the glycolytic enzymes with structural components of the cell suggest that the glycolytic enzymes are not entirely soluble in the cell. The relatively low affinities of the associations are likely responsible for the apparently transient interactions. The binding phenomenon is suggested to regulate metabolism through changes in enzymatic activity and facilitates localized enrichment of the enzymes.</p>","PeriodicalId":10933,"journal":{"name":"Current topics in cellular regulation","volume":"33 ","pages":"15-30"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/b978-0-12-152833-1.50007-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12668499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Citrate: its relation to free magnesium ion concentration and cellular energy.","authors":"H Kwack, R L Veech","doi":"10.1016/b978-0-12-152833-1.50016-2","DOIUrl":"https://doi.org/10.1016/b978-0-12-152833-1.50016-2","url":null,"abstract":"","PeriodicalId":10933,"journal":{"name":"Current topics in cellular regulation","volume":"33 ","pages":"185-207"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12668501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How carbohydrates cross the lipid membrane of bacterial cells.","authors":"H L Kornberg","doi":"10.1016/b978-0-12-152833-1.50009-5","DOIUrl":"https://doi.org/10.1016/b978-0-12-152833-1.50009-5","url":null,"abstract":"","PeriodicalId":10933,"journal":{"name":"Current topics in cellular regulation","volume":"33 ","pages":"49-63"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12668512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}