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Conservative political rhetoric and associated enduring threat to constitutional right to abortion—A case study from Brazil 保守派的政治言论和相关的对宪法规定的堕胎权的持久威胁--巴西的案例研究。
IF 2.8 2区 医学
Contraception Pub Date : 2024-11-08 DOI: 10.1016/j.contraception.2024.110737
Roberto Gonzalez Duarte , Israel Júnior Borges Do Nascimento
{"title":"Conservative political rhetoric and associated enduring threat to constitutional right to abortion—A case study from Brazil","authors":"Roberto Gonzalez Duarte ,&nbsp;Israel Júnior Borges Do Nascimento","doi":"10.1016/j.contraception.2024.110737","DOIUrl":"10.1016/j.contraception.2024.110737","url":null,"abstract":"<div><div>Abortion is a critical public issue in Brazil where over 800,000 abortions might occur each year, with approximately 250,000 admitted to emergency departments due to complications from unsafe procedures. A new bill seeks to amend the Brazilian Penal Code (<em>Código de Processo Penal</em>), classifying the practice as a felony for patients over 22 gestational weeks, even in cases where the practice is already legally foreseen (e.g., derived from sexual abuse, as an attempt to save pregnant individuals at high risk or due to fetuses’ anencephaly). This bill undermines several Sustainable Development Goals endorsed by the United Nations, particularly those related to health (Goal 3), gender equality (Goal 5), and inequality and poverty reduction (Goal 10). Among the extensive list of potential solutions to the abortion challenge that Brazil currently faces, a feasible and plausible alternative relates to investment in education, in particular sexual education aimed at adolescents.</div></div>","PeriodicalId":10762,"journal":{"name":"Contraception","volume":"143 ","pages":"Article 110737"},"PeriodicalIF":2.8,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the availability and accessibility of medication abortion pills in Delhi, India: A mystery client study in community pharmacies 探索印度德里药物流产药片的可用性和可及性:社区药房神秘顾客研究。
IF 2.8 2区 医学
Contraception Pub Date : 2024-11-08 DOI: 10.1016/j.contraception.2024.110745
Anvita Dixit , Dipesh Suvarna , Raywat Deonandan , Angel M. Foster
{"title":"Exploring the availability and accessibility of medication abortion pills in Delhi, India: A mystery client study in community pharmacies","authors":"Anvita Dixit ,&nbsp;Dipesh Suvarna ,&nbsp;Raywat Deonandan ,&nbsp;Angel M. Foster","doi":"10.1016/j.contraception.2024.110745","DOIUrl":"10.1016/j.contraception.2024.110745","url":null,"abstract":"<div><h3>Objectives</h3><div>Although medication abortion drugs technically require a prescription in India, research suggests that they are often available directly from pharmacies. We conducted a mystery client study in the capital city of Delhi to explore the availability, accessibility, and pharmacy dispensing practices of mifepristone/misoprostol in the absence of a prescription.</div></div><div><h3>Study design</h3><div>Using two predetermined client profiles—one of an unmarried woman and one of her male partner—we visited community pharmacies in different neighborhoods. Mystery clients began the interaction with a request for “a pill to bring back” a period after a positive pregnancy test. We documented product availability, price, and outcome and assessed the quality of the client–pharmacy worker interaction. We analyzed these encounters using descriptive statistics and for themes.</div></div><div><h3>Results</h3><div>In late 2022, we made 172 visits to 86 pharmacies. Medication abortion pills were available at more than half of the pharmacy visits (<em>n</em> = 91, 53%), and our mystery clients purchased the drugs without a prescription during 22% (<em>n</em> = 37) of all visits. The woman and man clients purchased mifepristone/misoprostol on a similar number of occasions, but we assessed the pharmacy worker interactions with the man as more positive. Pharmacy workers provided varied information about the regimen, and the encounters were brief.</div></div><div><h3>Conclusions</h3><div>Medication abortion drugs appear to be available without a prescription in a sizable minority of pharmacies in Delhi, India. Our findings suggest that identifying ways to work with pharmacy workers to support their ability to provide medically accurate information about the optimal mifepristone/misoprostol regimen is warranted.</div></div><div><h3>Implications</h3><div>Pharmacy access to mifepristone/misoprostol has the potential to greatly reduce barriers to accessing abortion care in India. Despite technically requiring a prescription, medication abortion drugs are available behind the counter at a sub-set of pharmacies in Delhi. Future research on formalizing and supporting pharmacy access and exploring abortion seekers’ experiences with pharmacy access is warranted.</div></div>","PeriodicalId":10762,"journal":{"name":"Contraception","volume":"143 ","pages":"Article 110745"},"PeriodicalIF":2.8,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthetic androgens for male contraception 用于男性避孕的合成雄激素。
IF 2.8 2区 医学
Contraception Pub Date : 2024-11-06 DOI: 10.1016/j.contraception.2024.110735
Stephanie T. Page
{"title":"Synthetic androgens for male contraception","authors":"Stephanie T. Page","doi":"10.1016/j.contraception.2024.110735","DOIUrl":"10.1016/j.contraception.2024.110735","url":null,"abstract":"<div><div>High global rates of unintended pregnancy (&gt;40% of all pregnancies) are relatively stagnant despite a broad array of female contraceptive options. Data suggest many men are enthusiastic to utilize novel, reversible, male contraceptives, particularly those that may be administered orally. Hormonal male contraception utilizes androgens or androgen-progestin combinations to exploit endocrine negative feedback, interrupting the hypothalamic-pituitary-testicular axis to suppress spermatogenesis. Modifications of testosterone allow for tailoring of steroid activity and show promise as single agent hormonal male contraceptives. The addition of progestin activity by molecular modification of testosterone could enhance the degree and speed of sperm suppression compared to testosterone alone using a single, exogenous steroid. Moreover, modifications that block reduction of testosterone to dihydrotestosterone could diminish androgenic stimulation of prostate tissue. This review summarizes data in the development of modified androgens for male hormonal contraception and suggest a path forward for these molecules in helping to fill the gap in contraceptive technologies for men.</div></div>","PeriodicalId":10762,"journal":{"name":"Contraception","volume":"145 ","pages":"Article 110735"},"PeriodicalIF":2.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of lifetime intimate partner violence on abortion method choice 终生亲密伴侣暴力对堕胎方式选择的影响》(The Impact of Lifetime Intimate Partner Violence on Abortion Method Choice)。
IF 2.8 2区 医学
Contraception Pub Date : 2024-11-05 DOI: 10.1016/j.contraception.2024.110732
Lauren Sobel , Madison Bernstein , Namita Arunkumar , Jennifer Fortin , Isabel Fulcher , Youri Hwang , Alisa B. Goldberg
{"title":"The impact of lifetime intimate partner violence on abortion method choice","authors":"Lauren Sobel ,&nbsp;Madison Bernstein ,&nbsp;Namita Arunkumar ,&nbsp;Jennifer Fortin ,&nbsp;Isabel Fulcher ,&nbsp;Youri Hwang ,&nbsp;Alisa B. Goldberg","doi":"10.1016/j.contraception.2024.110732","DOIUrl":"10.1016/j.contraception.2024.110732","url":null,"abstract":"<div><h3>Objective(s)</h3><div>To evaluate if the type of abortion patients prefer differs for those with a history of intimate partner violence (IPV) compared to those without a history of IPV.</div></div><div><h3>Study design</h3><div>We compared choice of medication versus procedural abortion between those with a history of lifetime IPV and those without a history of IPV among patients seeking abortion at 11 weeks’ gestation or less. Secondarily, we compared preferred abortion characteristics and assessed reproductive autonomy. Individuals presenting for abortion care were recruited for an anonymous, cross-sectional survey study at Planned Parenthood League of Massachusetts, Boston Health Center from September 2021 to August 2022. We required 336 subjects to detect a 20% difference in abortion method between those with a lifetime history of IPV and those without, with 80% power.</div></div><div><h3>Results</h3><div>We enrolled 342 participants and excluded six with missing data. A total of 71 individuals (21%) reported a lifetime history of IPV. A majority of individuals with a lifetime history of IPV chose procedural abortion, although their abortion method choice did not differ significantly from individuals with no history of IPV (56.3% vs 47.2%, <em>p</em> = 0.244). Individuals with a lifetime IPV history used abortion funds more frequently than those without a history of lifetime IPV (8.5% vs 1.5%, <em>p</em> = 0.047). There was no statistical difference between individuals with and without a lifetime history of IPV regarding what individuals considered important for the type of abortion they chose or reproductive autonomy.</div></div><div><h3>Conclusion(s)</h3><div>Access to procedural abortion services and abortion funds are important to meet the abortion needs of patients with a lifetime history of IPV.</div></div><div><h3>Implications</h3><div>Providing both medication and procedural abortion and creating a trauma-informed environment are central to supporting individuals with a history of IPV. Safeguarding abortion fund access is important individuals with a history of IPV.</div></div>","PeriodicalId":10762,"journal":{"name":"Contraception","volume":"143 ","pages":"Article 110732"},"PeriodicalIF":2.8,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Male contraception – Part of gender medicine and reproductive rights of men 男性避孕--性别医学和男性生殖权利的一部分。
IF 2.8 2区 医学
Contraception Pub Date : 2024-10-30 DOI: 10.1016/j.contraception.2024.110734
Johannes Bitzer
{"title":"Male contraception – Part of gender medicine and reproductive rights of men","authors":"Johannes Bitzer","doi":"10.1016/j.contraception.2024.110734","DOIUrl":"10.1016/j.contraception.2024.110734","url":null,"abstract":"<div><div>A pregnancy is in general the result of the sexual interaction of two individuals, with either different or same genders (male, female, non-binary etc). Preventing an unwanted pregnancy is therefore basically a “joint preventive behavior”, which can be achieved by <em>gender specific behaviors</em> with <em>gender specific methods</em> in a specific <em>sociocultural environment</em><strong>.</strong> This sociocultural environment (circumstances) determines the frame of gender specific behaviors (reproductive rights) and the available gender specific contraceptive methods (contraceptive technology). In the sociocultural history of contraception different models of contraceptive practice evolved from the patriarchal to the female emancipation model, with different balances and imbalances regarding these two basic components. Based on the concept of the “joint preventive behavior” not only reproductive rights including reproductive responsibilities, but also contraceptive choices should be as equally balanced as possible, to allow collaboration between two individuals involved in reproduction. The development and the broad availability of different male contraceptive methods allowing individualization and best fit between the method and the individual profile, will be an important way forward to achieve this goal.</div></div>","PeriodicalId":10762,"journal":{"name":"Contraception","volume":"145 ","pages":"Article 110734"},"PeriodicalIF":2.8,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of the SB 8 Texas abortion ban on pregnancy duration at time of abortion in a large volume Colorado clinic 德克萨斯州 SB 8 号堕胎禁令对科罗拉多州一家大型诊所堕胎时怀孕时间的影响。
IF 2.8 2区 医学
Contraception Pub Date : 2024-10-28 DOI: 10.1016/j.contraception.2024.110731
Eva Dindinger , Kate Coleman-Minahan , Jeanelle Sheeder , Nancy Z Fang
{"title":"The impact of the SB 8 Texas abortion ban on pregnancy duration at time of abortion in a large volume Colorado clinic","authors":"Eva Dindinger ,&nbsp;Kate Coleman-Minahan ,&nbsp;Jeanelle Sheeder ,&nbsp;Nancy Z Fang","doi":"10.1016/j.contraception.2024.110731","DOIUrl":"10.1016/j.contraception.2024.110731","url":null,"abstract":"<div><h3>Objectives</h3><div>To assess changes in type of abortion, gestational duration, and changes in the proportion of out-of-state residents at a university-affiliated clinic in Denver, Colorado after Texas passed Senate Bill 8 (SB 8) that banned abortion after embryonic cardiac activity can be detected.</div></div><div><h3>Study design</h3><div>We reviewed records of all visits of patients obtaining an abortion ≤22 weeks and 6 days gestation between January 2019 and June 2022. We created two time periods: before SB 8 (January 2019–August 2021) and after SB 8 (September 2021–June 2022). We assessed changes in type of abortion, gestational duration, and the proportion of out-of-state residents. We determined the odds of a second-trimester abortion (≥13 weeks and 0 day) after SB 8 using logistic regression models adjusted for gravida, parity, age, and the proportion of out-of-state residents.</div></div><div><h3>Results</h3><div>There were 3844 abortions: 2875 before and 969 after SB 8. Second trimester abortions increased from 16.8% to 24.4% for Colorado residents and from 19.5% to 33.5% for out-of-state residents (<em>p</em> &lt; 0.001). The proportion of patients that were Texas residents increased from 1.2% to 17.7% after SB 8 (<em>p</em> &lt; 0.001). The adjusted odds of a second trimester abortion nearly doubled overall (adjusted odds ratio [aOR] 1.86 95% CI 1.55–2.23) and for Colorado residents (aOR,1.76, 95% CI, 1.44–2.16, respectively), and more than doubled for out-of-state residents (aOR, 2.34, 95% CI,1.53–3.59).</div></div><div><h3>Conclusions</h3><div>Laws that ban abortion early in pregnancy delay care and increase abortions occurring later in pregnancy, not only for people forced to seek care out of state, but for residents of states with abortion access.</div></div><div><h3>Implications</h3><div>Our data suggests that abortion bans may increase wait times, gestational duration, and force people to travel great distances for care. As more states ban abortion or restrict abortion, surrounding states where abortion is protected may need to meet the needs of those traveling in addition to their in-state residents.</div></div>","PeriodicalId":10762,"journal":{"name":"Contraception","volume":"143 ","pages":"Article 110731"},"PeriodicalIF":2.8,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Society of Family Planning Committee Statement: Contraception and body weight 计划生育协会委员会声明:避孕与体重。
IF 2.8 2区 医学
Contraception Pub Date : 2024-10-11 DOI: 10.1016/j.contraception.2024.110725
Noor Zwayne , Elizabeth Lyman , Ashley Ebersole , Jessica Morse , with the assistance of Elise Boos and Antoinette Nguyen on behalf of the Clinical Affairs Committee, and Monica Skoko Rodríguez
{"title":"Society of Family Planning Committee Statement: Contraception and body weight","authors":"Noor Zwayne ,&nbsp;Elizabeth Lyman ,&nbsp;Ashley Ebersole ,&nbsp;Jessica Morse ,&nbsp;with the assistance of Elise Boos and Antoinette Nguyen on behalf of the Clinical Affairs Committee, and Monica Skoko Rodríguez","doi":"10.1016/j.contraception.2024.110725","DOIUrl":"10.1016/j.contraception.2024.110725","url":null,"abstract":"<div><div>Understanding the relationship between contraception and body weight is an important clinical consideration. Body weight and size has the potential to affect fertility and the effectiveness of some contraceptive methods, although historically this association has not been applied within a person-centered context that would allow individuals to select their preferred contraceptive method. Further, individuals with higher body weights and larger sizes have unmet contraceptive care and counseling needs. This document aims to provide evidence-based, person-centered, and equity-driven recommendations that destigmatize contraceptive care across all body weights. Clinicians should: provide person-centered, unbiased contraceptive care, including counseling pregnant-capable individuals on their risk of pregnancy based on sexual practices and contraceptive use regardless of body weight or size; utilize evidence-based and person-centered contraceptive counseling to offer the full range of contraceptive methods regardless of body weight or size; counsel patients about any risks and benefits associated with body weight and size to assist in their selection of contraceptive methods, including emergency contraception; counsel individuals about the potential for weight change, particularly weight gain, associated with contraceptive methods as a possible factor in decision-making; and counsel individuals regarding the potential impact of weight management approaches, such as bariatric surgery and glucagon-like peptide 1 (GLP-1) agonists, on contraceptive efficacy.</div></div>","PeriodicalId":10762,"journal":{"name":"Contraception","volume":"141 ","pages":"Article 110725"},"PeriodicalIF":2.8,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142483228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IMPROVING CARE FOR INDIVIDUALS WITH HIGHER BODY MASS INDEX (BMI) UNDERGOING INDUCTION TERMINATION 改善对体重指数(BMI)较高的接受引产终止妊娠者的护理
IF 2.8 2区 医学
Contraception Pub Date : 2024-10-07 DOI: 10.1016/j.contraception.2024.110584
M Fuerst, K Prewitt, B Garg, S Ramanadhan, L Han
{"title":"IMPROVING CARE FOR INDIVIDUALS WITH HIGHER BODY MASS INDEX (BMI) UNDERGOING INDUCTION TERMINATION","authors":"M Fuerst,&nbsp;K Prewitt,&nbsp;B Garg,&nbsp;S Ramanadhan,&nbsp;L Han","doi":"10.1016/j.contraception.2024.110584","DOIUrl":"10.1016/j.contraception.2024.110584","url":null,"abstract":"<div><h3>Objectives</h3><div>We aimed to examine the association of body mass index (BMI) with time to delivery for those undergoing induction of labor for pregnancy termination in the second or third trimester.</div></div><div><h3>Methods</h3><div>This is a retrospective cohort study including all patients with a singleton pregnancy undergoing induction termination at a single academic medical center over a 14-year period (1/2020-2/2024). Our primary outcome was time to fetal expulsion from the first medication given. BMI was categorized into four groups (&lt;18.5, 18.5-25, 25-30, and &gt;30). Kruskal-Wallis tests were used to compare median time to delivery among the BMI groups; and multivariable logistic regression models were used to assess the association of BMI with time to delivery ≥24 hours.</div></div><div><h3>Results</h3><div>Of the 428 charts reviewed, 393 patients met inclusion criteria. Of these, 290 (73.7%) had a BMI greater than 25. The median time to expulsion was significantly different among BMI categories (9 hours for BMI &lt; 18.5, 12 hours for BMI 18.5-25, 14 hours for BMI 25-30, and 20 hours for individuals with BMI &gt;30, p&lt;0.001). After adjusting for maternal age, gestational age, history of cesarean section and prior vaginal deliveries, individuals with a BMI &gt;30 had 6.74 times the odds (95%CI 3.24-14.00) of having a time to expulsion ≥24 hours compared to BMI 18.5-25.</div></div><div><h3>Conclusions</h3><div>We found individuals had a significantly longer time to delivery in second and third trimester induction terminations for patients with BMI &gt;30. Induction protocols may need to be adjusted to provide equitable care for individuals with higher BMI.</div></div>","PeriodicalId":10762,"journal":{"name":"Contraception","volume":"139 ","pages":"Article 110584"},"PeriodicalIF":2.8,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RACE AND ETHNICITY REPORTING AND REPRESENTATION IN US CONTRACEPTIVE CLINICAL TRIALS FROM 2007-2024 2007-2024 年美国避孕药具临床试验中的种族和民族报告及代表性
IF 2.8 2区 医学
Contraception Pub Date : 2024-10-07 DOI: 10.1016/j.contraception.2024.110578
N Fang, J Sheeder
{"title":"RACE AND ETHNICITY REPORTING AND REPRESENTATION IN US CONTRACEPTIVE CLINICAL TRIALS FROM 2007-2024","authors":"N Fang,&nbsp;J Sheeder","doi":"10.1016/j.contraception.2024.110578","DOIUrl":"10.1016/j.contraception.2024.110578","url":null,"abstract":"<div><h3>Objectives</h3><div>Contraceptive clinical trials inform policy and practice changes, yet participants are often non-representative of the US population. We aimed to characterize race and ethnicity reporting among completed contraceptive trials.</div></div><div><h3>Methods</h3><div>We queried ClinicalTrials.gov for all completed trials (2007–2024) with keywords “contraception” or “contraceptive.” We extracted all race and ethnicity participant data. If this was not reported, we manually reviewed linked publications. We categorized trials as “representative” or “non-representative” of the US population if the proportion of non-White participants were within 30% of the 2020 Census estimates. We described and compared trial characteristics for reporting and representation using chi-squared tests (IBM SPSS Version 29). The study included only publicly available data and was deemed exempt by the Colorado Multiple Institutional Review Board.</div></div><div><h3>Results</h3><div>We reviewed 129 trials meeting initial inclusion criteria; 55 were excluded for including non-US sites or the study was not related to contraception, leaving 74 for the final analysis. Most reported race or ethnicity (85.1%) and occurred in the West region (32.4%); 43.2% evaluated pharmacokinetics, safety, or efficacy. 68.9% were non-representative of the US population. Of those, 82.4% had overrepresentation of non-White participants. Trial phase, funder type, completion year, contraceptive method, and study type did not differ between “representative” and “non-representative” studies.</div></div><div><h3>Conclusions</h3><div>Race and ethnicity of participants in contraceptive trials are not representative of the US. Deliberate and thoughtful recruitment strategies are needed to ensure that contraceptive trials are diverse, inclusive, have adequate representation, and are not unintentionally over-recruiting populations with historical mistreatment within the research community.</div></div>","PeriodicalId":10762,"journal":{"name":"Contraception","volume":"139 ","pages":"Article 110578"},"PeriodicalIF":2.8,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
URGENT, EMERGENT, OR JUST MISSED? GEOPOLITICAL VARIATIONS IN THE MANAGEMENT OF EARLY PREGNANCY LOSS IN US EMERGENCY DEPARTMENTS 紧急、急诊还是错过?美国急诊科在处理早孕损失方面的地缘政治差异
IF 2.8 2区 医学
Contraception Pub Date : 2024-10-07 DOI: 10.1016/j.contraception.2024.110626
ED Lantos, LS Benson, R Sangara, P Garza, M Pearlman Shapiro, BT Nguyen
{"title":"URGENT, EMERGENT, OR JUST MISSED? GEOPOLITICAL VARIATIONS IN THE MANAGEMENT OF EARLY PREGNANCY LOSS IN US EMERGENCY DEPARTMENTS","authors":"ED Lantos,&nbsp;LS Benson,&nbsp;R Sangara,&nbsp;P Garza,&nbsp;M Pearlman Shapiro,&nbsp;BT Nguyen","doi":"10.1016/j.contraception.2024.110626","DOIUrl":"10.1016/j.contraception.2024.110626","url":null,"abstract":"<div><h3>Objectives</h3><div>We aimed to describe geopolitical variations in Emergency Medicine (EM) providers’ treatment of early pregnancy loss (EPL) and evaluated their attitudes toward directly managing EPL, with attention to the influence of post-<em>Dobbs v Jackson Women’s Health Organization</em> restrictions.</div></div><div><h3>Methods</h3><div>We distributed a nationwide anonymous survey to emergency medicine clinicians using specialty-specific listservs and social media platforms, exploring experience and comfort with EPL diagnosis and management, as well as relevant institutional and structural barriers, inclusive of state abortion restrictions. We examined associations between state restrictions and emergency medicine resources via bivariate analysis.</div></div><div><h3>Results</h3><div>Most participants (n=203) identified as female (56.6%), non-Hispanic White (69.0%), attendings (73.6%), in urban settings (82.7%) and abortion-permissive states (60.8%). Most reported comfort diagnosing (93.0%) and counseling (86%) about EPL. However, only 39.7% consistently counseled on all management options--expectant, medication, procedural. Participants in abortion-permissive states were significantly more likely to consistently offer comprehensive counseling (44.2% vs. 32.7%, p=0.02) and reported increased access to on-site Ob-Gyn consultation (49.6% vs. 27.5%, p=0.002). Regardless of restrictions, only 16.2% consistently prescribed mifepristone-misoprostol; fewer (3.5%) performed manual uterine aspiration. 49.7% felt stable patients experiencing EPL should not receive treatment in the ED; 48.7% felt Ob-Gyns should manage EPL; 44.0% reported that arranging follow-up was a barrier to management. The majority (78.1%) endorsed the importance of more training on medication management of EPL.</div></div><div><h3>Conclusions</h3><div>Less than 20% of emergency medicine clinicians consistently offer EPL treatment. On-site Ob-Gyn consultations remain an essential resource, though less accessible in abortion-restrictive states. Training emergency medicine providers to treat EPL and improving access to follow-up could improve care.</div></div>","PeriodicalId":10762,"journal":{"name":"Contraception","volume":"139 ","pages":"Article 110626"},"PeriodicalIF":2.8,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142426172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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