2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)最新文献

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Reconstruction of CT images from sparse-view polyenergetic data using total variation minimization 利用总变差最小化从稀疏视图多能数据重建CT图像
2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7582013
T. Humphries, A. Faridani
{"title":"Reconstruction of CT images from sparse-view polyenergetic data using total variation minimization","authors":"T. Humphries, A. Faridani","doi":"10.1109/NSSMIC.2015.7582013","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582013","url":null,"abstract":"Recent work in CT image reconstruction has seen increasing interest in the use of compressive sensing techniques to reconstruct images from sparse-view projection data, with the goal of reducing radiation dose as well as scan time. Most often these reconstruction approaches exploit sparsity in the gradient of the image using total variation (TV) minimization. Following the existing theoretical results from compressive sensing, these approaches typically assume a linear measurement model, which corresponds to data generated from a monoenergetic X-ray beam. Most clinical CT systems generate X-rays from a polyenergetic spectrum, however, which is inconsistent with a linear system model and produces the well-known beam hardening artifacts. Such artifacts have been observed in some studies on sparse-view CT reconstruction using a linear model. In this work we incorporate an existing polyenergetic iterative technique known as polyenergetic SART (pSART) into a TV minimization reconstruction algorithm. Using numerical phantom experiments, we demonstrate that this polyenergetic TV minimization algorithm is able to reconstruct images free of both undersampling and beam hardening artifacts from sparse-view, polyenergetic projection data.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"160 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124250948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Advanced Compton imagers: From universal exploration down to earth investigation and medical application 先进的康普顿成像仪:从宇宙探测到地球探测和医学应用
2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7582261
Wonho Lee, Taewoong Lee, Hyounggun Lee
{"title":"Advanced Compton imagers: From universal exploration down to earth investigation and medical application","authors":"Wonho Lee, Taewoong Lee, Hyounggun Lee","doi":"10.1109/NSSMIC.2015.7582261","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582261","url":null,"abstract":"Since Compton imaging technology was first introduced about 40 years ago, it has been applied to many fields such as astrophysics, industrial and medical application. In the early days, Compton camera started to be used to search for signals from space in which the high energy radiation comes from point sources. The application in astrophysics was followed by the investigation for nuclear material in which advanced systems such as hybrid collimation method were applied. The Compton cameras were also utilized to monitor the environmental radiations caused by nuclear accidents. In medical application, both conventional and recoiled electron tracking method was applied for emission tomography. Recent researches presented Monte Carlo studies of multiple scattering Compton imaging methods for the detection of neutron induced gamma rays and scattered gamma rays in 3D radiation therapy. In summary, we present the historical trend of Compton camera and advanced Compton imagers made by us.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124535280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fundamentals of a scalable network in SPADnet-based PET systems 基于spadnet的PET系统中可扩展网络的基本原理
2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7581985
Martijn Bijwaard, C. Veerappan, C. Bruschini, E. Charbon
{"title":"Fundamentals of a scalable network in SPADnet-based PET systems","authors":"Martijn Bijwaard, C. Veerappan, C. Bruschini, E. Charbon","doi":"10.1109/NSSMIC.2015.7581985","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581985","url":null,"abstract":"In SPADnet we have advocated the use of standardized photonic modules for modular assembly of PET systems. In this paper, we tackle the scalability problem, starting from synchronization. Since the photonic modules in a ring must ensure tens of picoseconds in timing accuracy, it is essential that the synchronization of each module be accurate, irrespective of the number of modules in a ring, the ring's size, and the number of rings in the system. We propose a hybrid solution, where a hard-wired clock synchronization network is combined with a network-based clock offset estimator. This combination enables scalability while maintaining high precision. A novel least squares synchronization algorithm is optimized and implemented in hardware equipped with a delay line FPGA TDC, allowing picosecond clock synchronization. The solution is verified in an 8 node system.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114599076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Performance evaluation of MAP algorithms with different penalties, object geometries and noise levels 不同惩罚、物体几何形状和噪声水平下MAP算法的性能评价
2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7582101
Yu-Jung Tsai, A. Bousse, Matthias Joachim Ehrhardt, B. Hutton, S. Arridge, K. Thielemans
{"title":"Performance evaluation of MAP algorithms with different penalties, object geometries and noise levels","authors":"Yu-Jung Tsai, A. Bousse, Matthias Joachim Ehrhardt, B. Hutton, S. Arridge, K. Thielemans","doi":"10.1109/NSSMIC.2015.7582101","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582101","url":null,"abstract":"A new algorithm (LBFGS-B-PC) which combines ideas of two existing convergent reconstruction algorithms, relaxed separable paraboloidal surrogate (SPS) and limited-memory Broyden-Fletcher-Goldfarb-Shanno with boundary constraints (LBFGS-B), is proposed. Its performance is evaluated in terms of log-posterior value and regional recovery ratio. The results demonstrate the superior convergence speed of the proposed algorithm to relaxed SPS and LBFGS-B, regardless of the noise level, activity distribution, object geometry, and penalties.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117288752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Study of antiproton annihilation in silicon with a hybrid pixel detector using the TimePix3 readout 用TimePix3读出的混合像素探测器研究硅中的反质子湮灭
2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7581982
H. Holmestad
{"title":"Study of antiproton annihilation in silicon with a hybrid pixel detector using the TimePix3 readout","authors":"H. Holmestad","doi":"10.1109/NSSMIC.2015.7581982","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581982","url":null,"abstract":"The main goal of the AEgIS experiments is to measure the gravitational force for anti-hydrogen, testing Einstein's weak equivalence principle, which states that all bodies falls with the same acceleration, independently from their mass and composition. The measurement will be done using an anti-hydrogen beam sent trough a classical moire deflectometer. To measure the deflection of the beam from a straight path a position sensitive silicon detector followed by an emulsion detector and a scintillating fiber time-of-flight detector will be used. We present here a study performed using a novel hybrid pixel detector, employing the Timepix3 readout chip to tag and spatially resolve antiproton annihilations in silicon. In autumn 2014 we performed a test-experiment on a secondary beam line to the AEgIS experiment, where a pulsed beam of anti-protons of energy 5.3 MeV was delivered from the Antiproton Decelerator of CERN accelerator complex. Taking advantage of the high spatial resolution, ToA capabilities and extended energy range of the Timepix3, this study investigates unique features of antiproton annihilation events in silicon. We are for the first time able to set clear criteria to characterize an antiproton annihilation using a silicon detector.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116030175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulse-shape analysis of neutron-induced scintillation light in Ni-doped 6LiF/ZnS ni掺杂6LiF/ZnS中中子诱发闪烁光的脉冲形状分析
2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7581914
C. Cowles, R. S. Behling, G. Imel, R. Kouzes, A. Lintereur, S. Robinson, S. Stave, E. Siciliano, Zheming Wang
{"title":"Pulse-shape analysis of neutron-induced scintillation light in Ni-doped 6LiF/ZnS","authors":"C. Cowles, R. S. Behling, G. Imel, R. Kouzes, A. Lintereur, S. Robinson, S. Stave, E. Siciliano, Zheming Wang","doi":"10.1109/NSSMIC.2015.7581914","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581914","url":null,"abstract":"Alternatives to 3He are being investigated for gamma-ray insensitive neutron detection applications, including plutonium assay. One promising material is lithium-6 fluoride with silver activated zinc sulfide 6LiF/ZnS(Ag) in conjunction with a wavelength shifting plastic. Doping the 6LiF/ZnS(Ag) with nickel (Ni) has been proposed as a means of reducing the decay time of neutron signal pulses. This research performed a pulse shape comparison between Ni-doped and non-doped 6LiF/ZnS(Ag) neutron pulses. The Ni-doped 6LiF/ZnS(Ag) had a 32.7% ± 0.3 increase in neutron pulse height and a 32.4% ± 0.3 decrease in neutron pulse time compared to the non-doped 6LiF/ZnS(Ag). Doping 6LiF/ZnS(Ag) with nickel may allow neutron detector operation with improved signal to noise ratios, and reduced pulse pileup affects, increasing the accuracy and range of source activities with which such a detector could operate.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"192 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122111202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tuning the intrinsic radiation of Lutetium based scintillators through selective neutron activation 通过选择性中子活化调谐镥基闪烁体的本禀辐射
2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7581830
V. Martin, S. Siegel, H. Rothfuss, L. Eriksson, C. Buchanan
{"title":"Tuning the intrinsic radiation of Lutetium based scintillators through selective neutron activation","authors":"V. Martin, S. Siegel, H. Rothfuss, L. Eriksson, C. Buchanan","doi":"10.1109/NSSMIC.2015.7581830","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581830","url":null,"abstract":"Lutetium Oxyorthosilicate (LSO) is an attractive scintillator for positron emission tomography (PET) imaging, due to its relatively high light output, short decay time, and high stopping power. LSO has a 2.6% natural abundance of Lu-176, a long-lived (3.78×1010 years) radioisotope that generates an intrinsic background. This low background rate has been capitalized on to perform PET quality checks and measure transmission data. In this work, LSO was exposed to the neutrons produced by the O-18(p, n)F-18 reaction in a Siemens Eclipse Cyclotron to selectively alter the intrinsic background rate. The cyclotron was run for a total of 1827 microamp-hours over two weeks, with mean proton energy of 11 MeV. Ten LSO pixels (4×4×20 mm3) were placed in locations selected for a desired neutron energy range. The range of neutron energies produced permitted the Lu-175(n,γ)Lu-176 and Lu-176(n,γ)Lu-177 reactions. Three of the pixels were placed behind polyethylene to further moderate the neutrons. The pixel's scintillation properties were measured to determine if they had been damaged by the irradiation. Gamma ray spectroscopy was performed for several weeks following the irradiation to evaluate the transmutations engendered. Despite an increase in trapping centers, scintillation properties were not changed, and the expected Lu-177 activation occurred.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117113601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance evaluation of an innovative integrated charge-sensitive preamplifier with dynamic range booster 带动态范围增强器的新型集成电荷敏感前置放大器的性能评价
2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7581811
A. Pullia, S. Capra
{"title":"Performance evaluation of an innovative integrated charge-sensitive preamplifier with dynamic range booster","authors":"A. Pullia, S. Capra","doi":"10.1109/NSSMIC.2015.7581811","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581811","url":null,"abstract":"In this work we present an innovative all integrated solution, which incorporates on the same chip both a low-noise low-power charge-sensitive preamplifier and an integrated range booster with second-order effect compensation. The booster is based on a particular Time-to-Amplitude Converter which generates analog signals whose amplitude is directly proportional to the energy of the events that caused saturation (ions, energetic charged particles). In this way a dynamic range from a few keV to more than 800 MeV is obtained.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"30 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120840461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Comparing front-end alternatives for SiPM's in single-photon time resolution applications 比较单光子时间分辨率应用中SiPM的前端替代方案
2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7581821
F. Ciciriello, F. Corsi, F. Licciulli, C. Marzocca, G. Matarrese
{"title":"Comparing front-end alternatives for SiPM's in single-photon time resolution applications","authors":"F. Ciciriello, F. Corsi, F. Licciulli, C. Marzocca, G. Matarrese","doi":"10.1109/NSSMIC.2015.7581821","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581821","url":null,"abstract":"Thanks to single photon detection capability and excellent intrinsic timing resolution, silicon photomultipliers represent an interesting solution in an increasing range of applications which require accurate evaluation of the arrival time of single photons. In this contribution, different front-end electronics solutions for this kind of detectors are compared, to find out more about the achievable timing performance. For this purpose, simple relationships have been established between the main parameters of both detector and preamplifier and the time resolution, expressed by means of the time jitter when leading edge discrimination is the chosen time pick-off technique. A simplified SiPM model, suitable to describe the very first part of the transient response of the detector to a photon which triggers an avalanche breakdown in one of its micro-cells, has been exploited. Considering also the effects of the parasitic inductance associated to the interconnections between detector and front-end electronics, we conclude that the current-mode read-out approach offers some advantages over the other considered design styles, thus representing the most suitable solution for single-photon timing measurement applications based on SiPM detectors.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128294520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Fast estimation of image variance for time-of-flight PET reconstruction 飞行时间PET重建中图像方差的快速估计
2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7582040
Mengdie Wang, G. Hu, G. El Fakhri, Hui Zhang, Quanzheng Li
{"title":"Fast estimation of image variance for time-of-flight PET reconstruction","authors":"Mengdie Wang, G. Hu, G. El Fakhri, Hui Zhang, Quanzheng Li","doi":"10.1109/NSSMIC.2015.7582040","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582040","url":null,"abstract":"The use of time-of-flight (TOF) information in positron emission tomography (PET) can significantly improve image quality. Many analytical expressions have been proposed to predict the variance of PET images. However, these methods become impractically time-consuming for TOF-PET. Our work is motivated by the goal of deriving a fast algorithm that can accurately predict image variance of TOF-PET. We first present an elegant expression for the improvement of image variance achieved by post-smoothed maximum likelihood expectation maximization (MLEM). Then we apply this expression to the variance prediction for TOF-PET. The proposed algorithm was validated by Monte Carlo simulation. Our results come close to achieving the goal, in that we can predict the image variance of TOF-PET for both uniform disk and realistic phantoms accurately with a significant reduction of computation time.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129344849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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