Collection of Czechoslovak Chemical Communications最新文献

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Solid-phase synthesis of 5’-capped mRNA with a phosphorothioate modification within triphosphate bridge 在三磷酸桥内进行硫代修饰的5 '端mRNA的固相合成
Collection of Czechoslovak Chemical Communications Pub Date : 2014-01-01 DOI: 10.1135/CSS201414244
Y. Thillier, C. Sallamand, E. Decroly, B. Canard, J. Vasseur, F. Debart
{"title":"Solid-phase synthesis of 5’-capped mRNA with a phosphorothioate modification within triphosphate bridge","authors":"Y. Thillier, C. Sallamand, E. Decroly, B. Canard, J. Vasseur, F. Debart","doi":"10.1135/CSS201414244","DOIUrl":"https://doi.org/10.1135/CSS201414244","url":null,"abstract":"","PeriodicalId":10674,"journal":{"name":"Collection of Czechoslovak Chemical Communications","volume":"14 1","pages":"244-245"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63713307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and properties of dinucleotide cap analogs containing a triazole ring within the oligophosphate bridge 寡磷酸桥内含三唑环的二核苷酸帽类似物的合成及性质
Collection of Czechoslovak Chemical Communications Pub Date : 2014-01-01 DOI: 10.1135/CSS201414289
S. Walczak, Przemyslaw Wanat, A. Nowicka, J. Zuberek, J. Kowalska, J. Jemielity
{"title":"Synthesis and properties of dinucleotide cap analogs containing a triazole ring within the oligophosphate bridge","authors":"S. Walczak, Przemyslaw Wanat, A. Nowicka, J. Zuberek, J. Kowalska, J. Jemielity","doi":"10.1135/CSS201414289","DOIUrl":"https://doi.org/10.1135/CSS201414289","url":null,"abstract":"","PeriodicalId":10674,"journal":{"name":"Collection of Czechoslovak Chemical Communications","volume":"37 1","pages":"289-290"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63713603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polymerase synthesis of new photocaged DNA 新光笼DNA的聚合酶合成
Collection of Czechoslovak Chemical Communications Pub Date : 2014-01-01 DOI: 10.1135/CSS201414392
Zuzana Vaníková, Michal Hocek
{"title":"Polymerase synthesis of new photocaged DNA","authors":"Zuzana Vaníková, Michal Hocek","doi":"10.1135/CSS201414392","DOIUrl":"https://doi.org/10.1135/CSS201414392","url":null,"abstract":"","PeriodicalId":10674,"journal":{"name":"Collection of Czechoslovak Chemical Communications","volume":"14 1","pages":"392-393"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63713675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three-dimensional DNA structures: design and biological applications 三维DNA结构:设计和生物学应用
Collection of Czechoslovak Chemical Communications Pub Date : 2014-01-01 DOI: 10.1135/CSS201414020
H. Sleiman
{"title":"Three-dimensional DNA structures: design and biological applications","authors":"H. Sleiman","doi":"10.1135/CSS201414020","DOIUrl":"https://doi.org/10.1135/CSS201414020","url":null,"abstract":"","PeriodicalId":10674,"journal":{"name":"Collection of Czechoslovak Chemical Communications","volume":"14 1","pages":"20-24"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63712378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conjugation strategies for systemic delivery of RNAi drugs RNAi药物系统递送的偶联策略
Collection of Czechoslovak Chemical Communications Pub Date : 2014-01-01 DOI: 10.1135/CSS201414048
M. Manoharan
{"title":"Conjugation strategies for systemic delivery of RNAi drugs","authors":"M. Manoharan","doi":"10.1135/CSS201414048","DOIUrl":"https://doi.org/10.1135/CSS201414048","url":null,"abstract":"","PeriodicalId":10674,"journal":{"name":"Collection of Czechoslovak Chemical Communications","volume":"14 1","pages":"48-51"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63712421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metal-mediated reactions to detect 5-methylcytosine and 5-hydroxymethylcytosine in DNA 金属介导的检测DNA中5-甲基胞嘧啶和5-羟甲基胞嘧啶的反应
Collection of Czechoslovak Chemical Communications Pub Date : 2014-01-01 DOI: 10.1135/CSS201414088
Gosuke Hayashi, A. Okamoto
{"title":"Metal-mediated reactions to detect 5-methylcytosine and 5-hydroxymethylcytosine in DNA","authors":"Gosuke Hayashi, A. Okamoto","doi":"10.1135/CSS201414088","DOIUrl":"https://doi.org/10.1135/CSS201414088","url":null,"abstract":"","PeriodicalId":10674,"journal":{"name":"Collection of Czechoslovak Chemical Communications","volume":"46 1","pages":"88-90"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63712552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Solution-phase synthesis of short oligo-2’-deoxyribonucleotides by using clustered nucleosides as a soluble support 用簇状核苷作为可溶性载体的短寡聚-2 ' -脱氧核糖核苷酸的液相合成
Collection of Czechoslovak Chemical Communications Pub Date : 2014-01-01 DOI: 10.1135/CSS201414312
V. Kungurtsev, P. Virta, H. Lönnberg
{"title":"Solution-phase synthesis of short oligo-2’-deoxyribonucleotides by using clustered nucleosides as a soluble support","authors":"V. Kungurtsev, P. Virta, H. Lönnberg","doi":"10.1135/CSS201414312","DOIUrl":"https://doi.org/10.1135/CSS201414312","url":null,"abstract":"Oligonucleotides are currently prepared by phosphoramidite chemistry on a solid support both in the laboratory[1,2] and on a large scale.[3] Although this will likely remain the case for the near future, there seems to be space for the development of a solution-phase synthesis for specific purposes. Short oligonucleotides are sometimes needed in research laboratories in a scale of hundreds of milligrams for DNA-based material chemistry and for spectroscopic and physical organic studies on structure, modification and interaction with protein fragments or small molecular entities, including metal complexes. Convenient solution-phase methodology would undoubtedly be useful for the preparation of such oligonucleotides in-house without any special equipment. In fact, numerous strategies for the elongation of oligonucleotides on soluble supports have been developed. Phosphoramidite,[4] H-phosphonate,[5] and phosphotriester[6,7] chemistries have been used for the solution-phase synthesis of oligonucleotides and their monothioate analogues[8–10] on a soluble polyethylene glycol (PEG) support.[11] Once the coupling is performed, the PEG-supported oligonucleotides may be isolated by precipitation in diethyl ether. More recently, oligonucleotides have been attached to an imidazolium tetrafluoroborate,[12] to an adamantyl tag,[13] and to acetylated and methylated β-cyclodextrin[14] for the same purpose, facilitating purification of oligonucleotides by precipitation, extractive workup, and flash chromatography, respectively. We now report a novel soluble-support-based strategy with properties that are highly useful for the synthesis of","PeriodicalId":10674,"journal":{"name":"Collection of Czechoslovak Chemical Communications","volume":"14 1","pages":"312-313"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63713215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conformation analysis of nucleoside analogues containing selenium and tellurium in five-membered pseudosugar ring 五元假糖环中含硒、碲核苷类似物的构象分析
Collection of Czechoslovak Chemical Communications Pub Date : 2014-01-01 DOI: 10.1135/CSS201414354
L. Slavětínská, R. Pohl, D. Rejman
{"title":"Conformation analysis of nucleoside analogues containing selenium and tellurium in five-membered pseudosugar ring","authors":"L. Slavětínská, R. Pohl, D. Rejman","doi":"10.1135/CSS201414354","DOIUrl":"https://doi.org/10.1135/CSS201414354","url":null,"abstract":"","PeriodicalId":10674,"journal":{"name":"Collection of Czechoslovak Chemical Communications","volume":"14 1","pages":"354-355"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63713391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Substrate specificity of E. coli uridine phosphorylase. Evidence of high-syn conformation of substrate 大肠杆菌尿苷磷酸化酶的底物特异性。底物高同步构象的证据
Collection of Czechoslovak Chemical Communications Pub Date : 2014-01-01 DOI: 10.1135/CSS201414213
C. S. Alexeev, K. Polyakov, G. Sivets, T. Safonova, S. Mikhailov
{"title":"Substrate specificity of E. coli uridine phosphorylase. Evidence of high-syn conformation of substrate","authors":"C. S. Alexeev, K. Polyakov, G. Sivets, T. Safonova, S. Mikhailov","doi":"10.1135/CSS201414213","DOIUrl":"https://doi.org/10.1135/CSS201414213","url":null,"abstract":"","PeriodicalId":10674,"journal":{"name":"Collection of Czechoslovak Chemical Communications","volume":"14 1","pages":"213-216"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63712800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
New aproches for synthesis of 5-modified 2’-deoxyuridines as potential inhibitors of M. tuberculosis growth 作为结核分枝杆菌生长抑制剂的5-修饰2 ' -脱氧尿苷的合成新方法
Collection of Czechoslovak Chemical Communications Pub Date : 2014-01-01 DOI: 10.1135/CSS201414217
I. Karpenko, E. R. Shmalenyuk, L. A. Alexandrova
{"title":"New aproches for synthesis of 5-modified 2’-deoxyuridines as potential inhibitors of M. tuberculosis growth","authors":"I. Karpenko, E. R. Shmalenyuk, L. A. Alexandrova","doi":"10.1135/CSS201414217","DOIUrl":"https://doi.org/10.1135/CSS201414217","url":null,"abstract":"","PeriodicalId":10674,"journal":{"name":"Collection of Czechoslovak Chemical Communications","volume":"14 1","pages":"217-219"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63712817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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