{"title":"Steven Sandberg-Lewis Functional Gastroenterology. Assessing and Addressing the Causes of Functional Gastrointestinal Disorders Portland, OR: NCNM Press, 2009. 199 pp. $34.95. ISBN 978-0-9771435-1-1","authors":"R. Brumback","doi":"10.1177/1533210110392957","DOIUrl":"https://doi.org/10.1177/1533210110392957","url":null,"abstract":"","PeriodicalId":10611,"journal":{"name":"Complementary Health Practice Review","volume":"19 1","pages":"80 - 81"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74118389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Kathi J. Kemper Mental Health, Naturally Elk Grove Village, IL: American Academy of Pediatrics, 2010. 621 pp. $19.95. ISBN 978-1-58110-310-6","authors":"R. Brumback","doi":"10.1177/1533210110392956","DOIUrl":"https://doi.org/10.1177/1533210110392956","url":null,"abstract":"","PeriodicalId":10611,"journal":{"name":"Complementary Health Practice Review","volume":"8 1","pages":"80 - 80"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85482986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment With Pantethine","authors":"Z. Horvath, L. Vécsei","doi":"10.1177/1533210110392944","DOIUrl":"https://doi.org/10.1177/1533210110392944","url":null,"abstract":"The current increase in cardiovascular and cerebrovascular morbidity is a growing burden for society. Consideration must therefore be given to compounds capable of slowing down these pathological processes without significant adverse effects. The natural vitamins pantetheine/pantothenic acid are major precursors of coenzyme A and acyl carrier protein, which are essential for fatty acid oxidation and participate in the metabolism of cholesterol and carbohydrates and in at least 70 other enzymatic processes. Following a number of theoretical considerations and clinical observations, various clinical studies have revealed that they possess significant beneficial effects. In particular, they demonstrate useful moderating effects on vascular pathological processes, lowering lipid levels, and inhibiting platelet functions and lipid peroxidation. Although they are natural, well-tolerated therapeutic agents, few controlled clinical trials have been conducted. The available data suggest the need for larger clinical trials and possible use of pantetheine/pantothenic acid as adjuvant therapy.","PeriodicalId":10611,"journal":{"name":"Complementary Health Practice Review","volume":"17 1","pages":"21 - 28"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90909425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emerging Issues in Vitamin K Research","authors":"Jennifer T. Truong, S. Booth","doi":"10.1177/1533210110392953","DOIUrl":"https://doi.org/10.1177/1533210110392953","url":null,"abstract":"Vitamin K is traditionally recognized for its role in blood clotting. More recently, new roles for vitamin K have emerged. The current evidence for the role of vitamin K in bone, cardiovascular, and reproductive health will be discussed. There will be a particular focus on populations who could be at risk for vitamin K deficiency.","PeriodicalId":10611,"journal":{"name":"Complementary Health Practice Review","volume":"22 1","pages":"73 - 79"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75627915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Thiamine (Vitamin B1)","authors":"Aviva Fattal-Valevski","doi":"10.1177/1533210110392941","DOIUrl":"https://doi.org/10.1177/1533210110392941","url":null,"abstract":"Thiamine (vitamin B 1) was the first B vitamin to have been identified. It serves as a cofactor for several enzymes involved in energy metabolism. The thiamine-dependent enzymes are important for the biosynthesis of neurotransmitters and for the production of reducing substances used in oxidant stress defenses, as well as for the synthesis of pentoses used as nucleic acid precursors. Thiamine plays a central role in cerebral metabolism. Its deficiency results in dry beriberi, a peripheral neuropathy, wet beriberi, a cardiomyopathy with edema and lactic acidosis, and Wernicke—Korsakoff syndrome, whose manifestations consist of nystagmus, ophthalmoplegia, and ataxia evolving into confusion, retrograde amnesia, cognitive impairment, and confabulation. Patients on a strict thiamine-deficient diet display a state of severe depletion within 18 days. The most common cause of thiamine deficiency in affluent countries is either alcoholism or malnutrition in nonalcoholic patients. Treatment by thiamine supplementation is beneficial for diagnostic and therapeutic purposes.","PeriodicalId":10611,"journal":{"name":"Complementary Health Practice Review","volume":"53 1","pages":"12 - 20"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89481554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"JEBCAM: Rebirth Brings New Life to an Old Journal and Scientific Scrutiny to the Field","authors":"R. Brumback","doi":"10.1177/1533210110392940","DOIUrl":"https://doi.org/10.1177/1533210110392940","url":null,"abstract":"Beginning with the dawn of human consciousness, disease and death have perplexed mankind and resulted in a variety of mystical, religious, and mythological explanations. Stories such as ‘‘Pandora’s box’’ helped provide a reason for disease and other human afflictions. As human societies appeared, certain individuals claimed to be endowed with a special knowledge concerning disease and death, and such personages are evident in early writings from communities in Asia, Africa, and Europe and in the oral traditions of other groups. With advancing civilization, knowledge concerning disease and death became codified and treatises were developed, such as the various papyri attributed to Imhotep in Egypt, the Corpus Hippocraticum from ancient Greece, the writings of Galen of Pergamon in Imperial Rome, the alQ an un fi’l-tibb (Canon of Medicine) by the Central Asian Islamic physician Ab u ‘Al i al-Husayn ibn ‘Abd All ah ibn S in a (also known as Ibn S in a or Avicenna), the Nei Ching Su Wen attributed to the Chinese Yellow Emperor Huang Ti, and the Hindu texts Atharvaveda, Caraka Samhita, and Sushruta Samhita. Over centuries, various adherents came to view these writings as hallowed texts. Although scientific inquiry provided stuttering advances in a variety of disciplines such as mathematics, chemistry, and physics (particularly after the European Renaissance), medicine tended to adhere to the ancient wisdom of these sacred teachings. For example, even though the Dutch scientist Antonie van Leeuwenhoek could see microorganisms with his microscope as early as the 1600s, the germ theory of disease did not reach ascendency until the late 1800s. Until science finally insinuated its way into medical thought in the 19th century, more harm than good generally resulted from care by the supposed healers. Even during the American Civil War (1861-1865), the accepted medical therapy for injuries and illness that could not be treated by amputation was either bloodletting or administration of calomel (mercurous chloride) purgatives, and not unexpectedly most patients receiving such treatments did not survive. Although by the 1800s university-trained physicians in Europe and America could finally begin to categorize and diagnose diseases based on some scientific understanding, the results of their treatments were generally no better than that of any other healing discipline. In fact, the famous 1891 painting The Doctor by Sir Luke Fildes depicted the ‘‘physician in our time’’ who could offer no effective therapy but instead could only sit in vigil until the child either miraculously recovered or died (Figure 1). Thus, from the early-1800s until the mid-1900s (through World War II), there was an explosion of health care theories and disciplines, many offering treatments that were less gruesome and equally effective (or ineffective) as compared with those advocated by the universitytrained medical establishment. Unfortunately, this was also a period of exponential growth","PeriodicalId":10611,"journal":{"name":"Complementary Health Practice Review","volume":"15 1","pages":"11 - 4"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74423718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Role of Vitamin D in Human Health: A Paradigm Shift","authors":"J. Lappe","doi":"10.1177/1533210110392952","DOIUrl":"https://doi.org/10.1177/1533210110392952","url":null,"abstract":"Vitamin D deficiency is pandemic, spanning many continents and including all ages, genders and racial/ethnic groups. Currently, world-wide attention is focused on the importance of vitamin D in optimizing health and preventing disease. This focus is largely the result of the scientific discovery that vitamin D receptors are present in nearly every tissue and cell in the body and that adequate vitamin D status is essential for optimal functioning of these tissues and cells. An impressive body of research has accumulated over the past two decades providing new information about the role of vitamin D in prevention of a broad range of diseases. The purpose of this paper is to provide a review of this new information.","PeriodicalId":10611,"journal":{"name":"Complementary Health Practice Review","volume":"50 1","pages":"58 - 72"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79793495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vitamin B6: Beyond Adequacy","authors":"D. Bender","doi":"10.1177/1533210110392946","DOIUrl":"https://doi.org/10.1177/1533210110392946","url":null,"abstract":"There is good agreement concerning average requirements and reference intakes for vitamin B6 but less agreement over safe upper levels from supplements. High-dose supplements cause sensory nerve damage. Supplements of vitamin B6 have been advocated for treatment of the premenstrual syndrome, with little evidence of efficacy. There are plausible mechanisms for an antidepressant action and protection against steroid hormone—dependent cancers but no evidence from clinical trials. Pyridoxamine reduces the glycation of proteins and so could be beneficial in preventing the adverse effects of poor glycemic control in diabetes. There are plausible mechanisms for an antihypertensive action but only suggestive evidence from small intervention trials. There is no evidence that supplements of vitamin B6 have any beneficial effect in hyperhomocysteinemia. There is neither a plausible mechanism nor any evidence from controlled trials for any effect of supplements of vitamin B6 in preventing a decline in cognitive function with aging, amelioration of dementia or autism, or improvement of the carpal tunnel syndrome.","PeriodicalId":10611,"journal":{"name":"Complementary Health Practice Review","volume":"14 1","pages":"29 - 39"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83843114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Fernández-Mejía, Maria-Luisa Lazo-de-la-Vega-Monroy
{"title":"Biological Effects of Pharmacological Concentrations of Biotin","authors":"C. Fernández-Mejía, Maria-Luisa Lazo-de-la-Vega-Monroy","doi":"10.1177/1533210110392947","DOIUrl":"https://doi.org/10.1177/1533210110392947","url":null,"abstract":"Understanding the molecular mechanisms of vitamins has opened new perspectives regarding the relationship between nutritional signals and biological functions, which, in turn, has led to the development of new therapeutic agents. Although little is known about water-soluble vitamins as genetic modulators, evidence about their effects on gene expression has grown. In the case of biotin, besides its role as a carboxylase prosthetic group, it also affects gene expression and has a wide repertoire of effects on biological functions. Only recently, the role of pharmacological concentrations of biotin on systemic functions has attracted attention, and it is now being reconsidered with the help of new technologies. This novel approach could lead to new perspectives in its use as a therapeutic agent. The present review is focused on the effects of pharmacological concentrations of biotin on several biological functions and on the biotin signaling pathways that participate in gene expression.","PeriodicalId":10611,"journal":{"name":"Complementary Health Practice Review","volume":"20 1","pages":"40 - 48"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90073301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vitamin C: Overview and Update","authors":"A. Schlueter, C. Johnston","doi":"10.1177/1533210110392951","DOIUrl":"https://doi.org/10.1177/1533210110392951","url":null,"abstract":"Vitamin C functions in enzyme activation, oxidative stress reduction, and immune function. There is considerable evidence that vitamin C protects against respiratory tract infections and reduces risk for cardiovascular disease and some cancers. Current trials are examining the efficacy of intravenous vitamin C as cancer therapy. Many experts believe that the recommended intakes for vitamin C (45 to 90 mg daily) are several orders of magnitude too low to support optimal vitamin C functionality. Also, there is a misperception that vitamin C deficiency disease (scurvy) is largely historical and rarely observed in developed nations. Physical symptoms of scurvy include swelling of the lower extremities, bleeding gums, fatigue, and hemorrhaging, as well as psychological problems, including depression, hysteria, and social introversion. The long-term safety of vitamin C supplementation seems evident as large investigations have noted reduced risk of mortality in vitamin C supplementing populations and in those with elevated plasma vitamin C concentrations.","PeriodicalId":10611,"journal":{"name":"Complementary Health Practice Review","volume":"70 1","pages":"49 - 57"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84091671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}