Congestive heart failure最新文献_第9页

Clinic dosing of beta blockers in chronic heart failure. -受体阻滞剂在慢性心力衰竭中的临床应用。

Congestive heart failure Pub Date : 2001-07-01 DOI: 10.1111/J.1527-5299.2001.00253.X

T. Ramahi, R. Rohlfs, N. Sheynberg, K. M. Engle, M. Longo

{"title":"Clinic dosing of beta blockers in chronic heart failure.","authors":"T. Ramahi, R. Rohlfs, N. Sheynberg, K. M. Engle, M. Longo","doi":"10.1111/J.1527-5299.2001.00253.X","DOIUrl":"https://doi.org/10.1111/J.1527-5299.2001.00253.X","url":null,"abstract":"Beta blockers improve survival and reduce morbidity of patients with chronic heart failure. Stringent dosing guidelines calling for a 1-hour observation period after initiation or up-titration of beta-blocker therapy might limit the use of beta blockers and increase the expense involved. This study was conducted to determine the usefulness of this observation period. Data were collected from 130 in-clinic postdosing observation periods for 34 stable chronic heart failure patients started on carvedilol. The mean left ventricular ejection fraction was 0.22±0.09, and the mean functional class was 2.5±0.6. No patient had greater than first-degree heart block. Carvedilol was started at 3.125 or 6.25 mg b.i.d., and the dose was doubled every 1-3 weeks. All patients were observed for 1-2 hours after initiation or dosage increase, and blood pressure and heart rate were measured hourly. The maximal daily dose was 50±31 mg. In none of the observation periods was there a decrease in the dose of beta blockers administered in the clinic. The predosing mean blood pressure was 110±15/71±10 mm Hg, and the mean heart rate was 78±13 bpm; the 1-hour postdosing mean blood pressure was 101±14/67±10 mm Hg (p is less than 0.001), and the heart rate was 78±13 bpm. The dose was decreased in six patients and medication was discontinued in three, all consequent to symptoms reported several days after dosage increase. Beta blockers can be safely initiated and up-titrated at home in properly selected and evaluated stable patients with chronic heart failure and severe left ventricular dysfunction resulting in mild or moderate impairment of functional capacity. (c)2001 by CHF, Inc.","PeriodicalId":10536,"journal":{"name":"Congestive heart failure","volume":"78 1","pages":"196-200"},"PeriodicalIF":0.0,"publicationDate":"2001-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84050587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-output cardiac failure in a patient with prostate cancer. 前列腺癌患者的高输出量心力衰竭。

Congestive heart failure Pub Date : 2001-07-01 DOI: 10.1111/J.1527-5299.2001.01010.X

L. S. Greci, A. Rashkow

引用次数: 0

Chronotropic incompetence: a case report. 变时机能不全1例。

Congestive heart failure Pub Date : 2001-07-01 DOI: 10.1111/J.1527-5299.2001.00251.X

P. Vandergoten, J. Vijgen, P. Timmermans, P. Dendale

引用次数: 1

Propionic acidemia: a rare cause of cardiomyopathy. 丙酸血症:一种罕见的心肌病病因。

Congestive heart failure Pub Date : 2001-07-01 DOI: 10.1111/J.1527-5299.2001.01011.X

A. Bhan, C. Brody

引用次数: 19

Examination of left ventricular contractile reserve by Doppler myocardial imaging in patients with dilated cardiomyopathy. 扩张型心肌病患者左室收缩储备的多普勒心肌显像研究。

Congestive heart failure Pub Date : 2001-07-01 DOI: 10.1111/J.1527-5299.2001.00252.X

T. Fülöp, I. Hegedüs, I. Edes

{"title":"Examination of left ventricular contractile reserve by Doppler myocardial imaging in patients with dilated cardiomyopathy.","authors":"T. Fülöp, I. Hegedüs, I. Edes","doi":"10.1111/J.1527-5299.2001.00252.X","DOIUrl":"https://doi.org/10.1111/J.1527-5299.2001.00252.X","url":null,"abstract":"Detection of left ventricular contractile reserve by means of dobutamine stress echocardiography is a well known technique. The aim of the present study was to detect velocity changes during the administration of dobutamine, to establish if Doppler myocardial imaging is a suitable method for determining left ventricular contractile reserve, and to determine if the technique provides more information than traditional stress echocardiography. Twenty-five patients (all males; mean age, 53.4 years) were examined for a clinical diagnosis of idiopathic dilated cardiomyopathy with a poor left ventricular systolic function (ejection fraction less than 30%). Doses of 5-10 and 20 mg/kg/min dobutamine were administered and elevated at 4-minute intervals. Ejection fraction was calculated using the Simpson rule. The peak systolic and the early and late diastolic velocities were measured in the basal segment of the septum and the inferior wall at baseline and at full dose of dobutamine. Results indicated that peak systolic velocity increased significantly, both in the septum (0.11±0.03 vs. 0.20±0.05 m/sec; p=0.001) and in the inferior wall (0.10±0.05 vs. 0.17±0.06 m/sec; p=0.03). Late diastolic velocities also increased significantly, both in the septum (0.17±0.05 vs. 0.22±0.07 m/sec; p=0.01) and in the inferior wall (0.18±0.08 vs.0.21±0.02 m/sec; p=0.01). There was a significant linear correlation between the relative increases in basal ejection fraction value and in peak systolic velocity upon dobutamine stimulation. Patients were divided into responders and nonresponders based on responses in either ejection fraction (25% relative increase) or peak systolic velocity (5 cm/s increase). This study concludes that 1) Doppler myocardial imaging is an adequate and simple technique to examine left ventricular contractile reserve; and 2) measurement of peak systolic velocity during dobutamine stimulation seems to be a simple and good indicator of left ventricular contractile reserve. (c)2001 CHF, Inc.","PeriodicalId":10536,"journal":{"name":"Congestive heart failure","volume":"7 1","pages":"191-195"},"PeriodicalIF":0.0,"publicationDate":"2001-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87506904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving heart failure care in the office setting. 在办公室环境中改善心力衰竭护理。

Congestive heart failure Pub Date : 2001-07-01 DOI: 10.1111/J.1527-5299.2001.00256.X

G. Miller, M. Mills, E. Havranek, J. Taylor, D. Ordin

引用次数: 0

When cancer and heart failure cross paths: a case report of severe cardiorenal compromise associated with the anti-CD20 monoclonal antibody rituximab in a patient with dilated cardiomyopathy. 当癌症和心力衰竭交叉路径:扩张型心肌病患者中抗cd20单克隆抗体利妥昔单抗相关的严重心肾损害病例报告

Congestive heart failure Pub Date : 2001-07-01 DOI: 10.1111/J.1527-5299.2001.01009.X

L. Nikolaidis

{"title":"When cancer and heart failure cross paths: a case report of severe cardiorenal compromise associated with the anti-CD20 monoclonal antibody rituximab in a patient with dilated cardiomyopathy.","authors":"L. Nikolaidis","doi":"10.1111/J.1527-5299.2001.01009.X","DOIUrl":"https://doi.org/10.1111/J.1527-5299.2001.01009.X","url":null,"abstract":"The authors describe the case of a 41-year-old man with end-stage, nonischemic dilated cardiomyopathy of 11 years' duration. The patient had been deemed ineligible for transplantation, despite his young age, when he was diagnosed with non-Hodgkin's lymphoma 7 years previously. Since he had survived the lymphoma without significant chemotherapy, while his cardiovascular and renal status continued to deteriorate, the issue was revisited. In an attempt to at least render him eligible for an assist device, a novel, promising, and reportedly nontoxic immunomodulation therapy for his lymphoma was employed. This consisted of infusion of the monoclonal antibody rituximab, specifically targeting the CD20 antigen on B cells. Despite testimonials concerning the benign nature of the treatment, the patient was unable to tolerate it and his clinical condition deteriorated rapidly, eventually leading to his death. The authors discuss potential mechanisms that might have accounted for the patient's cardiorenal compromise, with a focus on a very rare \"cytokine release\" syndrome attributed to this type of monoclonal antibody therapy and the probable interplay of cytokines in advanced heart failure. (c)2001 CHF, Inc.","PeriodicalId":10536,"journal":{"name":"Congestive heart failure","volume":"8 1","pages":"223-227"},"PeriodicalIF":0.0,"publicationDate":"2001-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87527902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Difficult cases in heart failure: Left ventricular dysfunction related to septic shock masquerading as postpartum cardiomyopathy. 心力衰竭的疑难病例:与感染性休克相关的左心室功能障碍伪装成产后心肌病。

Congestive heart failure Pub Date : 2001-07-01 DOI: 10.1111/J.1527-5299.2001.00258.X

I. Bukharovich, E. Harrison, T. L. Le Jemtel

引用次数: 2

Trastuzumab therapy and the heart: palliation at what cost? 曲妥珠单抗治疗和心脏:缓和的代价是什么?

Congestive heart failure Pub Date : 2001-07-01 DOI: 10.1111/J.1527-5299.2001.00241.X

S. Aikat, G. Francis

引用次数: 2

Using the transtheoretical approach to facilitate change in the heart failure population. 运用跨理论方法促进心力衰竭人群的改变。

Congestive heart failure Pub Date : 2001-05-01 DOI: 10.1111/J.1527-5299.2001.00244.X

J. Suppan

引用次数: 5