Clinical Nutrition (Edinburgh, Scotland)最新文献

{"title":"Albumin-bilirubin score as a useful predictor of energy malnutrition in patients with hepatocellular carcinoma.","authors":"Feiyan Zhu, Xiaofei Li","doi":"10.1016/j.clnu.2021.05.021","DOIUrl":"https://doi.org/10.1016/j.clnu.2021.05.021","url":null,"abstract":"","PeriodicalId":104901,"journal":{"name":"Clinical Nutrition (Edinburgh, Scotland)","volume":" ","pages":"3890"},"PeriodicalIF":6.3,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clnu.2021.05.021","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39236807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Change in skeletal muscle mass is associated with lipid profiles in female rheumatoid arthritis patients -TOMORROW study.","authors":"Yoshinari Matsumoto,&nbsp;Yuko Sugioka,&nbsp;Masahiro Tada,&nbsp;Tadashi Okano,&nbsp;Kenji Mamoto,&nbsp;Kentaro Inui,&nbsp;Daiki Habu,&nbsp;Tatsuya Koike","doi":"10.1016/j.clnu.2020.12.028","DOIUrl":"https://doi.org/10.1016/j.clnu.2020.12.028","url":null,"abstract":"<p><strong>Background & aims: </strong>To examine the relationship between changes in skeletal muscle mass and lipid metabolism and glycometabolism in patients with rheumatoid arthritis (RA).</p><p><strong>Methods: </strong>Data were analyzed from 148 female RA patients and 145 age-matched non-RA (control) female subjects from a prospective cohort study (TOMORROW; TOtal Management Of Risk factors in Rheumatoid arthritis patients to lOWer morbidity and mortality study). Appendicular skeletal muscle mass (ASM) was assessed using dual-energy x-ray absorptiometry and skeletal muscle mass index (SMI) was calculated as ASM divided by the square of height. The reference value for SMI in Asian women, 5.4 kg/m², was used to define low SMI. Data were assessed using cross-sectional (2010 baseline data) and longitudinal (change in value from 2010 to 2013) methods from the retrospective cohort.</p><p><strong>Results: </strong>At baseline in RA patients, the low SMI group showed significantly higher low-density lipoprotein cholesterol (LDL-chol) (p = 0.015), apolipoprotein (Apo)B (p = 0.046), and ApoB-to-A1 (ApoB/A1) (p = 0.025) than the normal SMI group. In multiple regression analysis of RA patients, sequential changes from 2010 to 2013 (Δ) in SMI and ApoB and ApoC2 showed significant negative relationships (β = -0.19, -0.18, respectively) even after adjusting for age, RA duration, exercise habits, medication for RA, disease severity, activities of daily living (ADL) and body fat mass. No significant relation was evident between ΔSMI and various glycometabolism parameters in RA patients.</p><p><strong>Conclusions: </strong>Skeletal muscle mass might be related to lipid metabolism in RA patients. This relationship is independent of factors such as disease severity and body fat mass.</p>","PeriodicalId":104901,"journal":{"name":"Clinical Nutrition (Edinburgh, Scotland)","volume":" ","pages":"4500-4506"},"PeriodicalIF":6.3,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38795214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fructose intake is not associated to the risk of hepatic fibrosis in patients with Non-Alcoholic Fatty Liver Disease (NAFLD).","authors":"Feiyan Zhu,&nbsp;Xiaofei Li","doi":"10.1016/j.clnu.2021.05.020","DOIUrl":"https://doi.org/10.1016/j.clnu.2021.05.020","url":null,"abstract":"","PeriodicalId":104901,"journal":{"name":"Clinical Nutrition (Edinburgh, Scotland)","volume":" ","pages":"3827"},"PeriodicalIF":6.3,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clnu.2021.05.020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39236806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply Letter to the Editor: Post-operative nutritional care of patients with gastrointestinal cancer: are long-term clinical outcomes achievable?","authors":"Shanjun Tan,&nbsp;Guohao Wu","doi":"10.1016/j.clnu.2021.03.035","DOIUrl":"https://doi.org/10.1016/j.clnu.2021.03.035","url":null,"abstract":"","PeriodicalId":104901,"journal":{"name":"Clinical Nutrition (Edinburgh, Scotland)","volume":" ","pages":"2555"},"PeriodicalIF":6.3,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clnu.2021.03.035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38936963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultra-processed food consumption and type 2 diabetes incidence: A prospective cohort study.","authors":"Renata B Levy, Fernanda Rauber, Kiara Chang, Maria Laura da C Louzada, Carlos A Monteiro, Christopher Millett, Eszter P Vamos","doi":"10.1016/j.clnu.2020.12.018","DOIUrl":"10.1016/j.clnu.2020.12.018","url":null,"abstract":"<p><strong>Background: </strong>Ultra-processed foods account for more than 50% of daily calories consumed in several high-income countries, with sales of ultra-processed foods soaring globally, especially in middle-income countries. The objective of this study is to investigate the association between ultra-processed food (UPF) consumption and risk of type 2 diabetes (T2D) in a UK-based prospective cohort study.</p><p><strong>Methods: </strong>Participants of the UK Biobank (2007-2019) aged 40-69 years without diabetes at recruitment who provided 24-h dietary recall and follow-up data were included. UPFs were defined using the NOVA food classification. Multivariable Cox proportional hazards regression models were used to evaluate the association between UPF consumption and the risk of T2D adjusting for socio-demographic, anthropometric and lifestyle characteristics.</p><p><strong>Results: </strong>A total of 21,730 participants with a mean age of 55.8 years and mean UPF intake of 22.1% at baseline were included. During a mean follow-up of 5.4 years (116,956 person-years), 305 incident T2D cases were identified. In the fully adjusted model, compared with the group in the lowest quartile of UPF intake, the hazard ratio for T2D was 1.44, 1.04-2.02 in the group with the highest quartile of UPF consumption. A gradient of elevated risk of T2D associated with increasing quartiles of UPF intake was consistently observed (p value for trend < 0.028). A significantly increased risk of T2D was observed per 10 percentage points increment in UPF consumption ([adjusted HR]: 1.12, 95% confidence interval [CI]: 1.04-1.20).</p><p><strong>Conclusions: </strong>Our findings demonstrate that a diet high in UPFs is associated with a clinically important increased risk of T2D. Identifying and implementing effective public health actions to reduce UPF consumption in the UK and globally are urgently required.</p>","PeriodicalId":104901,"journal":{"name":"Clinical Nutrition (Edinburgh, Scotland)","volume":" ","pages":"3608-3614"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39108127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High protein prescription in methylmalonic and propionic acidemia patients and its negative association with long-term outcome.","authors":"F Molema,&nbsp;H A Haijes,&nbsp;M C Janssen,&nbsp;A M Bosch,&nbsp;F J van Spronsen,&nbsp;M F Mulder,&nbsp;N M Verhoeven-Duif,&nbsp;J J M Jans,&nbsp;A T van der Ploeg,&nbsp;M A Wagenmakers,&nbsp;M E Rubio-Gozalbo,&nbsp;M C G J Brouwers,&nbsp;M C de Vries,&nbsp;S Fuchs,&nbsp;J G Langendonk,&nbsp;D Rizopoulos,&nbsp;P M van Hasselt,&nbsp;M Williams","doi":"10.1016/j.clnu.2020.12.027","DOIUrl":"https://doi.org/10.1016/j.clnu.2020.12.027","url":null,"abstract":"<p><strong>Background and objective: </strong>Methylmalonic acidemia (MMA) and propionic acidemia (PA) are inborn errors of metabolism. While survival of MMA and PA patients has improved in recent decades, long-term outcome is still unsatisfactory. A protein restricted diet is the mainstay for treatment. Additional amino acid mixtures (AAM) can be prescribed if natural protein is insufficient. It is unknown if dietary treatment can have an impact on outcome.</p><p><strong>Design: </strong>We performed a nationwide retrospective cohort study and evaluated both longitudinal dietary treatment and clinical course of Dutch MMA and PA patients. Protein prescription was compared to the recommended daily allowances (RDA); the safe level of protein intake as provided by the World Health Organization. The association of longitudinal dietary treatment with long-term outcome was evaluated.</p><p><strong>Results: </strong>The cohort included 76 patients with a median retrospective follow-up period of 15 years (min-max: 0-48 years) and a total of 1063 patient years on a protein restricted diet. Natural protein prescription exceeded the RDA in 37% (470/1287) of all prescriptions and due to AAM prescription, the total protein prescription exceeded RDA in 84% (1070/1277). Higher protein prescriptions were associated with adverse outcomes in severely affected patients. In PA early onset patients a higher natural protein prescription was associated with more frequent AMD. In MMA vitamin B12 unresponsive patients, both a higher total protein prescription and AAM protein prescription were associated with more mitochondrial complications. A higher AAM protein prescription was associated with an increased frequency of cognitive impairment in the entire.</p><p><strong>Conclusion: </strong>Protein intake in excess of recommendations is frequent and is associated with poor outcome.</p>","PeriodicalId":104901,"journal":{"name":"Clinical Nutrition (Edinburgh, Scotland)","volume":" ","pages":"3622-3630"},"PeriodicalIF":6.3,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clnu.2020.12.027","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38823847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcopenic obesity and its association with respiratory disease incidence and mortality - Authors' reply.","authors":"Fanny Petermann-Rocha,&nbsp;Shuai Yang,&nbsp;Stuart R Gray,&nbsp;Jill P Pell,&nbsp;Carlos Celis-Morales,&nbsp;Frederick K Ho","doi":"10.1016/j.clnu.2021.03.030","DOIUrl":"https://doi.org/10.1016/j.clnu.2021.03.030","url":null,"abstract":"","PeriodicalId":104901,"journal":{"name":"Clinical Nutrition (Edinburgh, Scotland)","volume":" ","pages":"2520"},"PeriodicalIF":6.3,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clnu.2021.03.030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38936957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of vitamin D pathway gene polymorphisms with vitamin D level during pregnancy was modified by season and vitamin D supplement.","authors":"Jinhua Wu,&nbsp;Bule Shao,&nbsp;Xing Xin,&nbsp;Wenliang Luo,&nbsp;Minjia Mo,&nbsp;Wen Jiang,&nbsp;Shuting Si,&nbsp;Shuojia Wang,&nbsp;Yu Shen,&nbsp;Yunxian Yu","doi":"10.1016/j.clnu.2020.12.029","DOIUrl":"https://doi.org/10.1016/j.clnu.2020.12.029","url":null,"abstract":"<p><strong>Background & aims: </strong>This study aims to explore the associations of vitamin D (VD) metabolic pathway gene with 25(OH)D level in pregnant women and the interactions of SNP with season and VD supplement.</p><p><strong>Methods: </strong>A total of 2658 pregnant women were selected from Zhoushan Pregnant Women Cohort study. Gestational 25(OH)D level and single nucleotide polymorphism (SNP) of VD metabolic pathway gene were detected. Multilinear regression models were used to estimate associations of SNPs with gestational 25(OH)D levels. Stratified analyses were performed to test the interactions of SNP with season and VD supplements.</p><p><strong>Results: </strong>The mutations of rs2298849 and rs7041 on the GC gene were respectively associated with higher 25(OH)D in the first and third trimester; the mutations of seven SNPs (rs1155563, rs16846876, rs17467825, rs2282679, rs2298850, rs3755967, and rs4588) on the GC gene were respectively associated with lower 25(OH)D both in the first and third trimester, and lower changes in 25(OH)D during late pregnancy. The mutations of above seven SNPs, except for rs1155563, were also respectively associated with lower 25(OH)D in the second trimester, but to a lesser extent; Besides, pregnant women with mutation on CYP24A1-rs2209314 had a higher increment in 25(OH)D than their counterparts in the second trimester. The increasing dose effect of Gc isoform on 25(OH)D was observed. The associations of GC and LRP2 genes with 25(OH)D modified by season and VD supplements.</p><p><strong>Conclusions: </strong>The polymorphisms of VD metabolic pathway gene were associated with gestational 25(OH)D, and the associations differ by seasons and VD supplements. Gc isoform exerted a profound influence on gestational 25(OH)D.</p>","PeriodicalId":104901,"journal":{"name":"Clinical Nutrition (Edinburgh, Scotland)","volume":" ","pages":"3650-3660"},"PeriodicalIF":6.3,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38801943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary inflammatory index (DII®) and the risk of depression symptoms in adults.","authors":"Prem Raj Shakya,&nbsp;Yohannes Adama Melaku,&nbsp;Nitin Shivappa,&nbsp;James R Hébert,&nbsp;Robert J Adams,&nbsp;Amanda J Page,&nbsp;Tiffany K Gill","doi":"10.1016/j.clnu.2020.12.031","DOIUrl":"https://doi.org/10.1016/j.clnu.2020.12.031","url":null,"abstract":"<p><strong>Background & aims: </strong>Findings from observational studies investigating the association between Dietary Inflammatory Index (DII®) scores and depression symptoms (DepS) are inconsistent. This study aims to assess the association between energy-adjusted DII (E-DII™) and DepS using the North West Adelaide Health Study (NWAHS) cohort as well as update a previous meta-analysis.</p><p><strong>Methods: </strong>A total of 1743 (mean ± SD age: 56.6 ± 13.6 years, 51% female) study participants from NWAHS were included in the cross-sectional study and 859 (mean ± SD age: 58.4 ± 12.1 years, 52.6% female) in the longitudinal analyses. The Center for Epidemiological Studies Depression Scale (CES-D) was used for the measurement of DepS. E-DII scores were calculated from the dietary data collected using a validated food frequency questionnaire (FFQ). Data from two stages [Stage 3 (2008-10) and North West 15 (NW15) (2015)] were used. Log- and negative binomial regression were used to assess the association between quartiles of E-DII and DepS. A recent meta-analysis was updated by including 12 publications (six cross-sectional and six cohort studies) on the association between DII and DepS.</p><p><strong>Results: </strong>In the cross-sectional analysis, a higher E-DII score (i.e., more pro-inflammatory diet) was associated with a 79% increase in odds of reporting DepS [OR_Quartile4vs1: 1.79; 95% CI: 1.14-2.81; p = 0.01; p for trend (p_trend) = 0.03]. Males with higher E-DII had a more than two-fold higher odds of DepS (OR_Quartile4vs1: 2.27; 95% CI: 1.02-5.06; p = 0.045; p_trend = 0.09). Females with higher E-DII had an 81% increase in odds of DepS (OR_Quartile4vs1: 1.81; 95% CI: 1.01-3.26; p = 0.046; p_trend = 0.07). These associations were consistent in the longitudinal analysis. Comparing highest to lowest quintiles of E-DII, the updated meta-analysis showed that a pro-inflammatory diet is associated with a 45% increase in odds of having DepS (OR: 1.45; 95% CI: 1.20-1.74; p < 0.01) with higher odds in females (OR: 1.53; 95% CI: 1.16-2.01; p = 0.01) compared to their male counterparts (OR: 1.29; 95% CI: 0.98-1.69; p = 0.15).</p><p><strong>Conclusion: </strong>The data from the NWAHS and the updated meta-analysis of observational studies provide further evidence that a pro-inflammatory diet is positively associated with increased risk of DepS. These findings support the current recommendation on consuming a less inflammatory diet to improve DepS.</p>","PeriodicalId":104901,"journal":{"name":"Clinical Nutrition (Edinburgh, Scotland)","volume":" ","pages":"3631-3642"},"PeriodicalIF":6.3,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clnu.2020.12.031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38851844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: A comment to \"dietary iron and vitamins in association with mortality\".","authors":"Giuseppe Cianciolo,&nbsp;Maria Cappuccilli","doi":"10.1016/j.clnu.2021.03.032","DOIUrl":"https://doi.org/10.1016/j.clnu.2021.03.032","url":null,"abstract":"","PeriodicalId":104901,"journal":{"name":"Clinical Nutrition (Edinburgh, Scotland)","volume":" ","pages":"2493"},"PeriodicalIF":6.3,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clnu.2021.03.032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38937458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}