Clinical ophthalmology最新文献

{"title":"Symptomatic Dry Eye Disease and Associated Factors Among Adult Diabetic Patients in Adare General Hospital, Hawassa City, Southern Ethiopia, 2023","authors":"Asnake Gezahegn Bekele, Yezinash Addis Alimaw, Melkamu Temeselew Tegegn","doi":"10.2147/opth.s433679","DOIUrl":"https://doi.org/10.2147/opth.s433679","url":null,"abstract":"Introduction: Symptomatic dry eye disease is a multifactorial ocular surface condition caused by disruption of the precorneal tear film and is a common clinical finding in diabetic patients. However, there was no study on the prevalence and associated factors of symptomatic dry eye disease among diabetic patients in Ethiopia or in the study area. Purpose: This study aimed to investigate the prevalence and associated factors of symptomatic dry eye disease among adult diabetic patients in Adare General Hospital, Hawassa City, Southern Ethiopia, in 2023. Methods: A hospital-based cross-sectional study design was conducted on 493 adult diabetic patients who were selected using systematic random sampling, from April 23 to June 8, 2023. Data were collected through a face-to-face interview using an ocular surface disease index questionnaire. Binary logistic regression was performed to identify factors potentially associated with symptomatic dry eye disease. Variable with a P value of < 0.05 was considered statistically significant. Results: A total of 488 subjects participated in this study with a response rate of 99%. The prevalence of symptomatic dry eye disease was 34.8% (95% CI = 30.6– 39.1). College and university educational status (AOR = 5.88, 95% CI = 2.25– 15.38), government employed (AOR = 2.22, 95% CI = 1.05– 4.68), use of visual display unit > 5 hours (AOR = 4.41, 95% CI = 1.51– 12.87), duration of diabetes ≥ 11 years (AOR = 3.57, 95% CI = 1.28– 9.90), poor glycemic control (AOR = 2.13, 95% CI = 1.21– 3.75), allergic conjunctivitis (AOR = 1.99, 95% CI = 1.12– 3.54), and debris in the tear film (AOR = 3.63, 95% CI = 1.53– 8.61) were positively associated with symptomatic dry eye disease. Conclusion: The study revealed a high prevalence of symptomatic dry eye disease. Higher educational status, government employed, use of visual display unit, longer duration of diabetes, poor glycemic control, allergic conjunctivitis, and tear film debris were significantly associated with symptomatic dry eye disease. Breaks in screen use, good glycemic control, and treatment of ocular morbidities such as allergic conjunctivitis and debris in the tear film were recommended for all diabetic patients. Keywords: symptomatic dry eye disease, Hawassa City, diabetic patients, Southern Ethiopia","PeriodicalId":10442,"journal":{"name":"Clinical ophthalmology","volume":"31 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135714952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Agreement and Variability Among Alternative Devices for Intraocular Pressure Measurement: A Comparative Study","authors":"Chen-Wei Lin, Jin-Jhe Wang, Chien-Hsiung Lai, Chau-Yin Chen, Ing-Chou Lai","doi":"10.2147/opth.s438358","DOIUrl":"https://doi.org/10.2147/opth.s438358","url":null,"abstract":"Purpose: Intraocular pressure (IOP) measurement is critical in diagnosing and managing eye conditions. This study aims to assess the comparability of three alternative devices for measuring IOP: Noncontact tonometer, Icare rebound tonometer, and Tono-Pen. Patients and Methods: A cross-sectional study included 172 adult participants (87 males and 85 females) who underwent IOP and central corneal thickness (CCT) assessments. IOP was measured using Noncontact (Canon TX-20), Icare (Icare TA01i), and Tono-Pen (Tonopen XL). CCT was measured with the built-in pachymetry of the Noncontact tonometer. Correlation coefficients and Bland-Altman analyses were conducted to assess the relationships and agreements between these tonometers. Participants were grouped based on IOP and CCT levels. The mean of the standard deviation of the three tonometer results was calculated to evaluate measurement result variability. One-way analysis of variance was conducted for comparing between the groups. Results: IOP measurements among the three devices were not significantly different, indicating their comparability. Correlation analysis revealed strong correlations between the tonometers. Bland-Altman analysis showed good agreement, with the Icare rebound tonometer and Tono-Pen exhibiting narrower limits of agreement. Furthermore, IOP levels influenced measurement result variability, with higher IOP levels associated with greater variance. Conclusion: This study demonstrates that the alternative devices examined can provide reliable IOP measurements. It highlights the potential of these alternative devices for IOP measurement. These findings have implications for clinical practice, offering practitioners additional tools for accurate IOP assessment. Keywords: intraocular pressure, tonometer, noncontact, icare, Tono-Pen","PeriodicalId":10442,"journal":{"name":"Clinical ophthalmology","volume":"31 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135765471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association of Cardiovascular and Neurological Comorbidities in Geriatric Patients Sustaining Ocular Trauma","authors":"Vincent Q Pham, Hannah Miller, Elise Fernandez, Daniel de Marchi, Hongtu Zhu, David Fleischman","doi":"10.2147/opth.s434804","DOIUrl":"https://doi.org/10.2147/opth.s434804","url":null,"abstract":"","PeriodicalId":10442,"journal":{"name":"Clinical ophthalmology","volume":"69 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135715201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Clinical Experience with a New Hydrophobic Acrylic Single-Piece Monofocal Intraocular Lens","authors":"Steven Schallhorn, David Teenan, Jan Venter, Julie Schallhorn, Stephen Hannan","doi":"10.2147/opth.s433530","DOIUrl":"https://doi.org/10.2147/opth.s433530","url":null,"abstract":"Purpose: To evaluate early clinical outcomes and adverse events (AEs) in cataract patients following implantation of a monofocal hydrophobic acrylic IOL with a new optimized non-constant aberration-correcting design (CT LUCIA 621P). Methods: This retrospective study included patients with visually significant cataracts who underwent implantation of the CT LUCIA 621P IOL. Refraction, corrected (CDVA) and uncorrected (UDVA) visual acuity of the last available visit were used in the analysis. Intraoperative and postoperative AEs of the cohort were reviewed. Results: A total of 191 eyes of 133 patients with the mean age of 70.2± 11.2 years were included in this study. The mean follow-up time of the last available visit was 1.7± 1.3 months. The mean postoperative monocular UDVA was 0.09± 0.16 logMAR (&ap;20/25), and 74.9% (143/191) eyes achieved ≥ 20/25 UDVA. The percentage of eyes with manifest spherical equivalent (MSE) within ± 0.50D and ± 1.00D of emmetropia was 84.8% (162/191) and 98.4% (188/191), respectively. Linear regression of attempted vs achieved MSE showed a tight relationship, with the coefficient of determination close to 1 (R 2 =0.99), indicating a very predictable refractive correction. The reported AEs were those typically expected after cataract surgery. There were no AEs related to intraoperative manipulation with the IOL/injector or to postoperative stability of the IOL in the capsular bag. No eye lost ≥ 2 lines of CDVA. Conclusion: The implantation of CT LUCIA 621P resulted in good refractive predictability and visual outcomes. No IOL-related adverse events were reported. Keywords: monofocal IOL, non-constant aberration-correcting optic design, cataract surgery","PeriodicalId":10442,"journal":{"name":"Clinical ophthalmology","volume":"28 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135715583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epiphora in Treated Lacrimal Drainage System Malignancy Patients – When and Whom to Treat? [Letter]","authors":"Shalin Shah, Ruchi Goel","doi":"10.2147/opth.s447229","DOIUrl":"https://doi.org/10.2147/opth.s447229","url":null,"abstract":"","PeriodicalId":10442,"journal":{"name":"Clinical ophthalmology","volume":"19 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135765173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence Improves Patient Follow-Up in a Diabetic Retinopathy Screening Program","authors":"Eliot R Dow, Karen M Chen, Cindy Zhao, Austen Knapp, Anuradha Phadke, Kirsti Weng, Diana V Do, Vinit B Mahajan, Prithvi Mruthyunjaya, Theodore Leng, David Myung","doi":"10.2147/opth.s422513","DOIUrl":"https://doi.org/10.2147/opth.s422513","url":null,"abstract":"","PeriodicalId":10442,"journal":{"name":"Clinical ophthalmology","volume":"154 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135326140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploration of Hippocampal Functional Connectivity Alterations in Patients with High Myopia via Seed-Based Functional Connectivity Analysis","authors":"Bin Wei, Wen-Wen Fu, Yu Ji, Qi Cheng, Ben-Liang Shu, Qin-Yi Huang, Xiao-Rong Wu","doi":"10.2147/opth.s434797","DOIUrl":"https://doi.org/10.2147/opth.s434797","url":null,"abstract":"","PeriodicalId":10442,"journal":{"name":"Clinical ophthalmology","volume":"70 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135715470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Treatment Duration and Clinical Outcomes in Dry Eye Treatment with Sutureless Cryopreserved Amniotic Membrane.","authors":"Marguerite McDonald,&nbsp;Susan B Janik,&nbsp;Frank W Bowden,&nbsp;Amit Chokshi,&nbsp;Michael A Singer,&nbsp;Sean Tighe,&nbsp;Olivia G Mead,&nbsp;Seema Nanda,&nbsp;Mujtaba A Qazi,&nbsp;Damon Dierker,&nbsp;Adam T Shupe,&nbsp;Brittany J McMurren","doi":"10.2147/OPTH.S423040","DOIUrl":"10.2147/OPTH.S423040","url":null,"abstract":"<p><strong>Background: </strong>While sutureless, cryopreserved amniotic membrane (cAM) has been shown to significantly improve signs and symptoms of dry eye disease (DED), no studies have assessed the association of cAM treatment duration to the differential response in clinical outcomes.</p><p><strong>Methods: </strong>A multi-center, retrospective study was conducted on patients with moderate-to-severe DED who were treated with self-retained cAM (Prokera^® Slim) for 2 to 7 days. The primary outcome measure was DEWS severity score assessed at 1 week, 1 month, and 3 months. Secondary outcome measures included ocular discomfort, visual symptoms, corneal staining, and visual acuity.</p><p><strong>Results: </strong>A total of 89 eyes (77 patients) with moderate-to-severe DED (DEWS severity 3.24 ± 0.56) received treatment with self-retained cAM for 2 days (n = 10), 3 days (n = 15), 4 days (n = 12), 5 days (n = 19), 6 days (n = 6), or 7 days (n = 27). DEWS scores significantly improved at 1 week, 1 month, and 3 months for all treatment duration groups, with no significant difference observed between groups at any timepoint. In addition to an improvement in DEWS severity scores, those receiving cAM treatment for 2 days demonstrated a significant improvement in corneal staining, visual symptoms, and ocular discomfort at 1 week, 1 month, and 3 months.</p><p><strong>Conclusion: </strong>This retrospective study suggests that a single placement of self-retained cAM for 2 days can significantly improve signs and symptoms of DED with a lasting benefit observed for up to 3 months.</p>","PeriodicalId":10442,"journal":{"name":"Clinical ophthalmology","volume":"17 ","pages":"2697-2703"},"PeriodicalIF":2.2,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b6/b7/opth-17-2697.PMC10505017.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10286541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis and Management Strategies in Sclerochoroidal Calcification: A Systematic Review.","authors":"Ahmet Kaan Gündüz,&nbsp;Diğdem Tetik","doi":"10.2147/OPTH.S399058","DOIUrl":"10.2147/OPTH.S399058","url":null,"abstract":"<p><p>Sclerochoroidal calcification (SCC) is a rare disease which is characterized by calcium deposition in the sclera. The choroid is secondarily involved. Typical localization is in the midperipheral region, outside the vascular arcades. SCC is mostly located in the superotemporal quadrant. Often times, the patients are referred with the diagnosis of an amelanotic tumor. SCC may be dystrophic or metastatic. Metastatic SCC lesions are associated with conditions altering calcium and phosphate metabolism including primary and secondary hyperparathyroidism, vitamin D intoxication, renal failure, hyperphosphatemia, and destructive bony lesions. SCC lesions have a characteristic appearance and appear as distinct, ill-defined, yellow-white, elevated scleral/choroidal masses funduscopically. The purpose of this literature review is to review the current knowledge on SCC, highlight the imaging features, and discuss the differential diagnosis as well as management options.</p>","PeriodicalId":10442,"journal":{"name":"Clinical ophthalmology","volume":"17 ","pages":"2665-2686"},"PeriodicalIF":2.2,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/87/53/opth-17-2665.PMC10503566.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10279956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Determinants of Symptomatic Dry Eye Disease Among Adult Urban Residents of High-Altitude Areas of Southwest Saudi Arabia - A Survey.","authors":"Saad Abbas Aldawsari,&nbsp;Nazih Alzaidi,&nbsp;Maram E A Abdalla Elsayed,&nbsp;Abdullah Ahmed Alhammadi,&nbsp;Hadeel Khaled Alharthi,&nbsp;Abdulrahman Alosaimi,&nbsp;Yahya Al-Najmi","doi":"10.2147/OPTH.S427101","DOIUrl":"10.2147/OPTH.S427101","url":null,"abstract":"<p><strong>Purpose: </strong>To estimate the prevalence and determinants of Ocular Surface Disease Index (OSDI) score based dry eye disease (DED) among the adult urban population of four cities located at high altitudes in Southwest Saudi Arabia.</p><p><strong>Methods: </strong>This cross-sectional survey was held in 2023. OSDI questionnaire was used to collect the responses of the adult participants. The score was further graded into none, mild, moderate, and severe DED to estimate age-sex-adjusted DED prevalence. The OSDI score was correlated to demographic (age group, gender, education, occupation, city) and risk factors like smoking and co-morbidities.</p><p><strong>Results: </strong>Of the 401 adults, 388 (response rate of 97.8%) participated. The age-sex-adjusted prevalence of mild, moderate, and severe DED was 21.7%, 13.1%, and 32%, respectively. The median ODSI score was 22.9 [Interquartile range (IQR) 10.4; 47.9)]. The score was significantly higher in females (Mann-Whitney <i>U</i>-test P = 0.038), residents of Taif city (KW P = 0.05), those with primary/middle school education (Kruskal-Wallis P = 0.004), comorbidities like hypertension, asthma (KW P < 0.001) and risk factors like past refractive surgeries, arthritis (KW P = 0.013). Education status (P <0.001) [B = -9.0 95%] and presence of comorbidity (P = 0.022), [B = -0.823] were significant predictors of DED.</p><p><strong>Conclusion: </strong>The prevalence of DED and severe grade was high. The level of education and presence of comorbidities significantly influenced DED in the adult urban Saudi population of cities at high altitudes.</p>","PeriodicalId":10442,"journal":{"name":"Clinical ophthalmology","volume":"17 ","pages":"2687-2695"},"PeriodicalIF":2.2,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/65/19/opth-17-2687.PMC10503548.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10279963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}