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Clinical Medicine (Russian Journal)最新文献

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Results of treatment of patients with post-burn strictures of the esophagus by the booging method 用沸腾法治疗烧伤后食道狭窄患者的结果
Clinical Medicine (Russian Journal) Pub Date : 2024-04-15 DOI: 10.30629/0023-2149-2024-102-1-36-39
S. I. Sukovatkin, R. Sulimanov, S. E. Suzdaltsev, I. V. Korotkov, O. Y. Kalyuzhnaya, T. M. Gasainiev
{"title":"Results of treatment of patients with post-burn strictures of the esophagus by the booging method","authors":"S. I. Sukovatkin, R. Sulimanov, S. E. Suzdaltsev, I. V. Korotkov, O. Y. Kalyuzhnaya, T. M. Gasainiev","doi":"10.30629/0023-2149-2024-102-1-36-39","DOIUrl":"https://doi.org/10.30629/0023-2149-2024-102-1-36-39","url":null,"abstract":"To date, treatment of cicatricial post-burn strictures of the esophagus remains one of the main challenges of thoracic surgery. Despite the signifi cant number of diff erent treatment methods, the number of patients requiring it,  does not decrease. Conservative methods are mostly ineff ective. Bougienage of the esophagus remains the main method of treating scar strictures after burns.","PeriodicalId":10439,"journal":{"name":"Clinical Medicine (Russian Journal)","volume":"60 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140700202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Side effects of proton pump inhibitors: how real are they in clinical practice? 质子泵抑制剂的副作用：临床实践中的副作用有多大？
Clinical Medicine (Russian Journal) Pub Date : 2024-04-15 DOI: 10.30629/0023-2149-2024-102-1-57-61
A. Sheptulin, A. A. Kirilovsky, K. Kirilovskaya
{"title":"Side effects of proton pump inhibitors: how real are they in clinical practice?","authors":"A. Sheptulin, A. A. Kirilovsky, K. Kirilovskaya","doi":"10.30629/0023-2149-2024-102-1-57-61","DOIUrl":"https://doi.org/10.30629/0023-2149-2024-102-1-57-61","url":null,"abstract":"The presented article discusses the risk of side eff ects when using proton pump inhibitors (PPI): infectious complications (small intestinal bacterial overgrowth, Clostridium difficile-associated disease, community-acquired pneumonia, spontaneous bacterial peritonitis), stomach cancer, myocardial infarction, hypomagnesemia, iron and vitamin B12 deficiency, kidney damage, bone fractures, dementia, Alzheimer’s disease. An analysis of the literature indicates a weak causal relationship between the occurrence of these diseases and the use of PPI. Nevertheless, it is necessary to strive for the appointment of these drugs in the minimum effective dose and for as short a time as possible.","PeriodicalId":10439,"journal":{"name":"Clinical Medicine (Russian Journal)","volume":"331 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140703333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypotheses. Тheories. Practice (95th anniversary of academician Andrey Ivanovich Vorobyov) 假设。理论。实践（安德烈-伊万诺维奇-沃罗比约夫院士诞辰 95 周年）
Clinical Medicine (Russian Journal) Pub Date : 2024-04-15 DOI: 10.30629/0023-2149-2024-102-1-90-96
P. A. Vorobyov
{"title":"Hypotheses. Тheories. Practice (95th anniversary of academician Andrey Ivanovich Vorobyov)","authors":"P. A. Vorobyov","doi":"10.30629/0023-2149-2024-102-1-90-96","DOIUrl":"https://doi.org/10.30629/0023-2149-2024-102-1-90-96","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":10439,"journal":{"name":"Clinical Medicine (Russian Journal)","volume":"10 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140700682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Вакцинопрофилактика пневмококковой инфекции в особых группах риска: современные клинические рекомендации 特殊风险人群肺炎球菌感染的疫苗预防：当前的临床建议
Clinical Medicine (Russian Journal) Pub Date : 2024-04-15 DOI: 10.30629/0023-2149-2024-102-1-62-68
A. A. Zaĭtsev, N. I. Briko, V. G. Akimkin, I. V. Shubin
{"title":"Вакцинопрофилактика пневмококковой инфекции в особых группах риска: современные клинические рекомендации","authors":"A. A. Zaĭtsev, N. I. Briko, V. G. Akimkin, I. V. Shubin","doi":"10.30629/0023-2149-2024-102-1-62-68","DOIUrl":"https://doi.org/10.30629/0023-2149-2024-102-1-62-68","url":null,"abstract":"Pneumococcal infection is a serious problem for practical healthcare. After the COVID-19 pandemic, there has been a significant increase in bacterial infections incidence, with pneumococcus remaining the main causative agent in all age groups. Among military personnel, pneumococcal pneumonia is the most common severe pathology requiring significant efforts in patient treatment. Vaccination remains an important factor in reducing the incidence of disease, and most importantly, in significant reduction of cases of invasive pneumococcal infection, which is characterized by high mortality. Currently, modern approaches to vaccination regimens in adults have been developed, which are reflected in this publication.","PeriodicalId":10439,"journal":{"name":"Clinical Medicine (Russian Journal)","volume":"55 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140699214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of arterial rigidity and daily profile of arterial pressure in women with newly detected breast cancer 评估新发现乳腺癌妇女的动脉僵化程度和每日动脉压力曲线
Clinical Medicine (Russian Journal) Pub Date : 2024-04-15 DOI: 10.30629/0023-2149-2024-102-1-40-47
T. Brodskaya, T. S. Satalkina, B. Geltser, V. N. Kotelnikov
{"title":"Assessment of arterial rigidity and daily profile of arterial pressure in women with newly detected breast cancer","authors":"T. Brodskaya, T. S. Satalkina, B. Geltser, V. N. Kotelnikov","doi":"10.30629/0023-2149-2024-102-1-40-47","DOIUrl":"https://doi.org/10.30629/0023-2149-2024-102-1-40-47","url":null,"abstract":"Research objective: to evaluate arterial stiff ness indicators and its correlation with parameters of 24-hour ambulatory blood pressure monitoring (ABPM) in women with newly diagnosed breast cancer (BC).Material and methods: a prospective cohort study in 158 women aged 27 to 64 years with a median age of 45.4 years and newly diagnosed BC at stage IIA–IIIB before chemotherapy was conducted. The first group included 109 patients with normal or high-normal office blood pressure (BP), and the second group included 49 women with previously diagnosed stage 1– 2 essential hypertension (EH) with low or moderate cardiovascular risk. All patients underwent indirect arteriography and ABPM. Results. According to ABPM data, “masked” arterial hypertension (MAH) was diagnosed in 54 (49.5%) women in the fi rst group. In patients with MAH, the mean daily level and diastolic BP time index exceeded the corresponding indicators in EH, and the magnitude of the morning rise in systolic BP was significantly lower. In 35.4% of the examined patients with EH, the pulse wave velocity (PWV) was increased, and in 17.4% it was pathological. With MAH, these changes were recorded in 28.5% and 14.1% of cases, respectively. The odds ratio showed that in women with normal BP, the probability of an increase in PWV >10 m/s increased by 1.6 times, and in the presence of comorbidity with MAH and EH, it increased by 2.2 and 2.4 times, respectively. The risk of an increase in central systolic BP >125 mm Hg and pulse BP >60 mm Hg was highest in patients with EH.Conclusion: Among young and middle-aged women with newly diagnosed BC, a significant number of cases of MAH and EH are detected, which determines the need to evaluate arterial stiff ness and daily BP profiles before starting antitumor therapy.","PeriodicalId":10439,"journal":{"name":"Clinical Medicine (Russian Journal)","volume":"48 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140701956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aviation and medicine. Gatchina Officer Aviation School 航空与医学加特契纳军官航空学校
Clinical Medicine (Russian Journal) Pub Date : 2024-04-15 DOI: 10.30629/0023-2149-2024-102-1-80-84
P. E. Krynyukov, A. G. Abashin, I. I. Velichko
{"title":"Aviation and medicine. Gatchina Officer Aviation School","authors":"P. E. Krynyukov, A. G. Abashin, I. I. Velichko","doi":"10.30629/0023-2149-2024-102-1-80-84","DOIUrl":"https://doi.org/10.30629/0023-2149-2024-102-1-80-84","url":null,"abstract":"Data on the first military aeronautical schools in Gatchina and in Kacha are presented. Information is given about the first military doctors of aeronautical schools and the first studies of the effect of flights on the human body.","PeriodicalId":10439,"journal":{"name":"Clinical Medicine (Russian Journal)","volume":"331 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140703334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac amyloidosis, features of diagnosis and treatment 心脏淀粉样变性，诊断和治疗特点
Clinical Medicine (Russian Journal) Pub Date : 2024-04-15 DOI: 10.30629/0023-2149-2024-102-1-27-35
A. Demyanenko, N. A. Varavin, A. A. Santakov
{"title":"Cardiac amyloidosis, features of diagnosis and treatment","authors":"A. Demyanenko, N. A. Varavin, A. A. Santakov","doi":"10.30629/0023-2149-2024-102-1-27-35","DOIUrl":"https://doi.org/10.30629/0023-2149-2024-102-1-27-35","url":null,"abstract":"Cardiac amyloidosis is considered a rare disease, but as diagnostic capabilities increase, so does the assessment of its prevalence. Cardiac amyloidosis manifests itself with symptoms of restrictive cardiomyopathy, leading to progressive heart failure. However, the underlying pathogenetic mechanisms of the disease differ. This literature review provides an overview of cardiac amyloidosis, from classification to molecular mechanisms and modern treatment options.","PeriodicalId":10439,"journal":{"name":"Clinical Medicine (Russian Journal)","volume":"341 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140703212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Midwifery: legends and myths of Ancient Russia through the eyes of contemporaries 助产：当代人眼中的古俄罗斯传说与神话
Clinical Medicine (Russian Journal) Pub Date : 2024-04-15 DOI: 10.30629/0023-2149-2024-102-1-85-89
V. G. Abashin, S. V. Beskrovniy
{"title":"Midwifery: legends and myths of Ancient Russia through the eyes of contemporaries","authors":"V. G. Abashin, S. V. Beskrovniy","doi":"10.30629/0023-2149-2024-102-1-85-89","DOIUrl":"https://doi.org/10.30629/0023-2149-2024-102-1-85-89","url":null,"abstract":"The article presents some data on maternity care in Ancient Russia. The connection of myths and legends of Ancient Russia, Ancient Greece and Rome with modern elements of medical care for women in labor and newborns is traced.","PeriodicalId":10439,"journal":{"name":"Clinical Medicine (Russian Journal)","volume":"42 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140701735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extracellular neutrophil traps in cardiovascular diseases: problems and prospects of research 心血管疾病中的细胞外中性粒细胞陷阱：研究问题与前景
Clinical Medicine (Russian Journal) Pub Date : 2024-04-12 DOI: 10.30629/0023-2149-2024-102-1-19-26
Y. Skirdenko, M. A. Zorkina, D. G. Novikov, A. N. Zolotov, K. Andreev, K.  G. Zinchenko, N. A. Nikolaev
{"title":"Extracellular neutrophil traps in cardiovascular diseases: problems and prospects of research","authors":"Y. Skirdenko, M. A. Zorkina, D. G. Novikov, A. N. Zolotov, K. Andreev, K.  G. Zinchenko, N. A. Nikolaev","doi":"10.30629/0023-2149-2024-102-1-19-26","DOIUrl":"https://doi.org/10.30629/0023-2149-2024-102-1-19-26","url":null,"abstract":"One of the links in the pathogenesis of cardiovascular diseases is chronic low-intensity systemic inflammation. In 2004, a previously unknown process was discovered — the formation of extracellular neutrophil traps (NETs) — NETosis (n eutrophil extracellular traps). NETs play a role in antimicrobial immunity though in certain cases they become a factor in the development of pathology. This review presents data on the effect of extracellular neutrophil traps on individual pathologies of the cardiovascular system (atherosclerosis, atrial fibrillation, thrombosis). The authors describe the mechanisms of NET formation (vital NETosis, suicidal NETosis) and their role in thrombus formation (as a framework for thrombus formation, initiation of coagulation), in the development of endothelial dysfunction, and electrical heterogeneity of the atrial myocardium. Data are presented indicating the connection between atherosclerosis, thrombosis, and atrial fibrillation with the activity of NETosis. Most studies demonstrate existing correlations on laboratory models, while the determination of NETs in patients with cardiovascular pathology in real clinical practice is almost absent. At the same time, understanding the processes associated with NETosis can help to identify specific markers and further strategies for the therapy of cardiovascular diseases.","PeriodicalId":10439,"journal":{"name":"Clinical Medicine (Russian Journal)","volume":"4 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140709986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical and social aspects of preeclampsia 子痫前期的医疗和社会问题
Clinical Medicine (Russian Journal) Pub Date : 2024-04-12 DOI: 10.30629/0023-2149-2024-102-1-12-18
Yu. V. Shkurenko, A. D. Ibatov, U. E. Alieva
{"title":"Medical and social aspects of preeclampsia","authors":"Yu. V. Shkurenko, A. D. Ibatov, U. E. Alieva","doi":"10.30629/0023-2149-2024-102-1-12-18","DOIUrl":"https://doi.org/10.30629/0023-2149-2024-102-1-12-18","url":null,"abstract":"Preeclampsia (PE) is a relevant healthcare problem and represents a high risk for the development of various diseases in both the mother and fetus. In domestic and foreign literature, the number of works on the influence of PE on the cardiovascular and nervous systems of the fetus is constantly increasing. Thus, PE is associated with an increased risk of congenital heart defects, high blood pressure (BP), increased body mass index (BMI), and systemic vascular dysfunction in off spring. In addition, PE leads to disorders of the development of the nervous system, such as attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). PE is one of the main causes of adverse perinatal outcomes and neonatal mortality. This review also presents the correlation between PE and the risk of developing cardiovascular diseases (CVDs), stroke, and chronic kidney disease (CKD). In recent decades, there has been increasing evidence that manifestations of PE are not limited to pregnancy but also increase the risk of long-term complications. Thus, PE is a common disease that can lead to severe consequences for the mother and fetus in later life.","PeriodicalId":10439,"journal":{"name":"Clinical Medicine (Russian Journal)","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140710101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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