Clinical Gastroenterology最新文献

{"title":"IDDF2023-ABS-0231 The study of clinical characteristics and intestinal microbiota of pediatric clostridiodes difficile infection","authors":"Xiaolu Li, Yizhong Wang, Ting Zhang","doi":"10.1136/gutjnl-2023-iddf.208","DOIUrl":"https://doi.org/10.1136/gutjnl-2023-iddf.208","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"38 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72563127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IDDF2023-ABS-0284 Efficacy of probiotics pretreatment for intestinal preparation before colonoscopy in children with chronic constipation","authors":"Tong Li","doi":"10.1136/gutjnl-2023-iddf.216","DOIUrl":"https://doi.org/10.1136/gutjnl-2023-iddf.216","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74980382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IDDF2023-ABS-0181 Prevalence and risk factors for overweight among chinese adolescents","authors":"Junjie Huang, V. Keung, C. K. Cheung, A. S. Lo, S. Chan, W. Pang, L. W. Mui, Albert Lee, Martin C. S. Wong","doi":"10.1136/gutjnl-2023-iddf.202","DOIUrl":"https://doi.org/10.1136/gutjnl-2023-iddf.202","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79024237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IDDF2023-ABS-0141 The evolving role of technology in delivering patient-centric care in inflammatory bowel disease – an australasian experience using crohn’s colitis care e-health patient portal","authors":"Jack McNamara, J. Pipicella, S. Connor, J. Andrews","doi":"10.1136/gutjnl-2023-iddf.193","DOIUrl":"https://doi.org/10.1136/gutjnl-2023-iddf.193","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81514935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IDDF2023-ABS-0016 The potential causal relationship between inflammatory bowel disease and cirrhosis in East Asian populations: a two-sample Mendelian randomization study","authors":"Y. Deng, M. Wong","doi":"10.1136/gutjnl-2023-iddf.161","DOIUrl":"https://doi.org/10.1136/gutjnl-2023-iddf.161","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86134320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IDDF2023-ABS-0288 Diagnostic value of fecal PE-1 test in pancreatic exocrine insufficiency","authors":"Manping Li, Hao Wu, Wen‐Bin Zou, Z. Liao, Zhaoshen Li","doi":"10.1136/gutjnl-2023-iddf.217","DOIUrl":"https://doi.org/10.1136/gutjnl-2023-iddf.217","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87267486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IDDF2023-ABS-0160 Fecal microbiota transplantation in patients with mild to moderate ulcerative colitis is associated with early clinical response in a real-world setting","authors":"S. Virmani, B. Kante, S. Vuyyuru, Peeyush Kumar, M. Singh, G. Makharia, S. Kedia, V. Ahuja","doi":"10.1136/gutjnl-2023-iddf.197","DOIUrl":"https://doi.org/10.1136/gutjnl-2023-iddf.197","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85341172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IDDF2023-ABS-0012 Gastrointestinal cancers are the leading cause of young onset cancer in the United States","authors":"Benjamin Koh, Darren Jun-Hao Tan, Cheng-Han Ng, Wen-Hui Lim, Rebecca Wenling Zeng, Clarissa Elysia Fu, Jieling Xiao, Jia-Hong Koh, Benjamin Nah, Nicholas Syn, Margaret Teng, Ken Liu, Tamaki Nobuharu, Mark Muthiah, Chong-choon Seng, Vincent L Chen, Khay Guan Yeoh, Rohit Loomba","doi":"10.1136/gutjnl-2023-iddf.159","DOIUrl":"https://doi.org/10.1136/gutjnl-2023-iddf.159","url":null,"abstract":"<h3>Background</h3> Emerging data suggest that the incidence of young-onset cancers, defined as cancer diagnosed in adults < 50 years, is increasing, but has not been systematically assessed. We aimed to evaluate temporal changes in the incidence of young-onset cancers in a large, nationwide cohort study. <h3>Methods</h3> We analyzed data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results 17 registry from 2000 to 2019. Age-standardised incidence rates (ASIR) per 100,000 from 2010 to 2019 were extracted for young-onset cancers based on ICD-O-3 definitions, with rates age-adjusted to the United States standard population. The annual percentage change (APC) of the ASIRs were estimated via the SEER*Stat program. <h3>Results</h3> Between 2010 and 2019, a total of 562,145 cases of early-onset cancer (62.5% female) were recorded (IDDF2023-ABS-0012 Table 1). A total of 425,718 cases (75.7%) were White, 62,780 (11.2%) were Black, 55,976 (10.0%) were Asian or Pacific Islander individuals, 5120 (0.9%) were American Indian/Alaska Native and 12,551 (2.2%) were of unknown race. From 2010 to 2019, the annual percentage change of early-onset cancer was +0.276%, 95% CI 0.085 to 0.467%, p = 0.01(IDDF2023-ABS-0012 Table 2). There was lower APC in males vs females, -0.366 vs +0.667, p < 0.001. The APC in Whites, Blacks, Asians or Pacific Islanders, American Indian/Alaska Natives, and unknown races were +0.173, -0.637, +0.990, +1.170 and undefined, respectively. Gastrointestinal cancers were the fastest-growing cause of young-onset cancer (APC 2.161%, 95% CI: 1.660 - 2.665%), followed by urinary tract cancers (APC 1.336%, 95% CI: 0.607 – 2.070%), and breast cancers (APC 0.906%, 95% CI: 0.554 - 1.259%). Among gastrointestinal cancers, miscellaneous digestive organ cancers had the highest APC from 2010 to 2019 (APC 12.19%, 95% CI 9.99-14.43%), followed by cancers of the small intestine (APC 2.107%), stomach (APC 1.595%), and transverse colon (APC 1.689%). <h3>Conclusions</h3> The incidence of young-onset cancers is increasing in the United States. In particular, the incidence of the young-onset appendix, intrahepatic bile duct, and miscellaneous digestive organ cancers are rapidly rising. These data have important implications for surveillance strategies.","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136027395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IDDF2023-ABS-0222 Endoscopic ultrasound eus-s guided splenic lesion biopsy; noninvasive modality as an alternative to splenectomy","authors":"A. Urrehman, Aneel Madhwani, F. Ismail, O. Prakash, Z. Abbas, Zeeshan Uddin","doi":"10.1136/gutjnl-2023-iddf.206","DOIUrl":"https://doi.org/10.1136/gutjnl-2023-iddf.206","url":null,"abstract":"","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"147 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77587469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IDDF2023-ABS-0173 Towards a new paradigm for the diagnostic of irritable bowel syndrome: a case study of the use of the raid-dx test","authors":"Josep Oriol Miquel-Cusachs, Marc Albert Carrasco, Leyanira Torrealba, Esther Fort Martorell, David Busquets Casals, Javier Pamplona Portero, Miriam Sabat Mir","doi":"10.1136/gutjnl-2023-iddf.200","DOIUrl":"https://doi.org/10.1136/gutjnl-2023-iddf.200","url":null,"abstract":"<h3>Background</h3> Retrospective review of the use of RAID-Dx, a test for the positive diagnosis of irritable bowel syndrome (IBS) through a faecal microbial signature. Data are presented by the Gastroenterology Department at the <i>Hospital Universitari de Girona Dr. Josep Trueta – Institut d’Assistència Sanitària</i> in the Girona area (Spain). <h3>Methods</h3> Observational, retrospective study with patients that meet ROME III/IV criteria for IBS who undergo the RAID-Dx test. A total of 34 patients were included (40.5±14.7 years, 60% women). <h3>Results</h3> The suspected diagnosis consisted of 7 IBS-diarrheal (20.6%), 12 IBS-mixed (35.3%), 4 IBS-constipation (11.8%), 5 IBS-undefined (14.7%), 3 IBS-post diverticulitis (8.9%), 1 dyspepsia (2.9%), and 1 with gastroesophageal reflux (2.9%). The RAID-Dx results showed that 58.8% of the patients presented a diagnosis compatible with IBS. 76.5% of patients showed some altered markers; the most affected was <i>E. coli</i> (44.1%), followed by <i>A. muciniphila</i> (32.4%). The results allowed to confirm the initial diagnostic suspicion in 67.7% of the cases, and a different diagnosis was reached in 81.1% of the remaining. Thus, the RAID-Dx assisted 94.1% of the diagnoses. Once the test was performed, 70.6% did not require additional diagnostic tests, starting treatment in 94.1% of cases. Treatments for patients diagnosed with IBS included I3.1 (30.3%), Bifibran (soluble fibre) (15.2%), compared with 17.4% I3.1, 30.4% Spiraxin, and 17.4% received a specific diet when obtained an incompatible diagnosis. Throughout the study, clinical improvement was observed after treatment in 76.5% of cases (52.9% total, 23.5% partial), of which 81.8% had obtained a positive diagnosis for IBS. On average, 78% of patients had received more than 4 visits before their referral to specialist care, specifically 5.7 visits for the group not compatible with IBS and doubling to 11.7 visits in patients with IBS. After performing the test, 87.5% of the patients had between 1 and 3 visits until hospital discharge. <h3>Conclusions</h3> The use of RAID-Dx could optimize the diagnosis of IBS and rationalize the use of healthcare resources by avoiding additional tests, shortening the time of diagnosis, and accelerating access to appropriate treatment.","PeriodicalId":10401,"journal":{"name":"Clinical Gastroenterology","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136027399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}