Obesity Hypoventilation Syndrome, Central Sleep Apnoea and Neurologic Diseases最新文献

筛选

英文中文

Mortality rate in obstructive sleep apnea and in obesity hypoventilation syndrome 阻塞性睡眠呼吸暂停和肥胖低通气综合征的死亡率

Obesity Hypoventilation Syndrome, Central Sleep Apnoea and Neurologic Diseases Pub Date : 2019-04-11 DOI: 10.1183/23120541.SLEEPANDBREATHING-2019.P23

Tuomas Itäluoma, Hanna-Riikka Kreivi, A. Bachour

引用次数: 0

Obesity Hypoventilation Syndrome and Haematocrit levels: predictor for mortality? 肥胖低通气综合征和红细胞压积水平:预测死亡率?

Obesity Hypoventilation Syndrome, Central Sleep Apnoea and Neurologic Diseases Pub Date : 2019-04-11 DOI: 10.1183/23120541.SLEEPANDBREATHING-2019.P22

N. Arish, R. Riha

{"title":"Obesity Hypoventilation Syndrome and Haematocrit levels: predictor for mortality?","authors":"N. Arish, R. Riha","doi":"10.1183/23120541.SLEEPANDBREATHING-2019.P22","DOIUrl":"https://doi.org/10.1183/23120541.SLEEPANDBREATHING-2019.P22","url":null,"abstract":"Background: The connection between obstructive sleep apnea and secondary erythrocytosis is controversial. We hypothesized that there could be a higher prevalence of erythrocytosis in patients with Obesity hypoventilation syndrome due to persistent hypoxemia. Methods: We undertook a retrospective, cross-sectional review of OHS patients forming part of an established cohort of “Non -invasive ventilation “patients at the Department of Sleep Medicine at the Royal Infirmary Medical Centre, Edinburgh (2004-2017). We obtained the relevant clinical data from patient9s records. Results: The cohort comprised 74 OHS patients. Overall there were 44 men (59.5 %) and 30 women (40.5%). The mean age at diagnosis was 54 yrs. (25-75 SD 10). The mean Haematocrit level for the group overall was 0.44, in men the mean Hct was 0.45 and 0.41 in women. Eleven patients had erythrocytosis (14.9%), seven were men and 4 were women. Thirteen patients (17.5%) died during follow- up (2004-2017). There was a statistically significant increase in risk of death in patients with higher and lower haematocrit levels compared to OHS patients with normal haematocrit. Conclusions: To our knowledge, this is the first study showing increased prevalence of erythrocytosis in OHS patients. We found a “U” shape correlation with mortality according to haematocrit levels.","PeriodicalId":103744,"journal":{"name":"Obesity Hypoventilation Syndrome, Central Sleep Apnoea and Neurologic Diseases","volume":"103 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114001558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

首页上一页