{"title":"Enhancing the Delivery of Educational Content for Patients Starting Cancer Treatment.","authors":"Margaret L Wagnerowski, Rachel K Bishop","doi":"10.1188/26.CJON.291-297","DOIUrl":"10.1188/26.CJON.291-297","url":null,"abstract":"<p><strong>Background: </strong>Oncology nurses educate patients and caregivers about treatment. At one cancer center, treatment education was previously delivered via an in-person group class offered twice weekly to adults. This educational approach strained available resources, prompting the team to identify a new method for educating patients.</p><p><strong>Objectives: </strong>This quality improvement initiative aimed to implement a longer interval between patient education and first treatment to enhance patients' retention of educational content and maintain resource-neutral workflows.</p><p><strong>Methods: </strong>Educational videos were developed and made available in the patient portal, via email, or for in-clinic viewing by the patient or caregiver. Scripting was developed for nurses to conduct teach-back during follow-up calls, which standardized content and teach-back delivery. The time from patient education to treatment initiation was compared for different educational methods.</p><p><strong>Findings: </strong>This quality improvement project increased the length of time between patient education delivery and cancer treatment initiation. Patients and nurses reported satisfaction with the new process, and patients appreciated the opportunity to directly ask a nurse questions.</p>","PeriodicalId":10350,"journal":{"name":"Clinical journal of oncology nursing","volume":"30 4","pages":"291-297"},"PeriodicalIF":0.9,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13464537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148677347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephany Villacres, Joseph D Tariman, Catherine A Stubin
{"title":"Patient Care Bundle to Reduce Neutropenic Sepsis, Hospital Admissions, and Treatment Delays.","authors":"Stephany Villacres, Joseph D Tariman, Catherine A Stubin","doi":"10.1188/26.CJON.270-274","DOIUrl":"10.1188/26.CJON.270-274","url":null,"abstract":"<p><p>Chemotherapy-induced neutropenia is a frequent complication in patients with cancer that can lead to severe outcomes like sepsis, hospitalizations, and treatment delays. A neutropenic sepsis care bundle was implemented in an.</p>","PeriodicalId":10350,"journal":{"name":"Clinical journal of oncology nursing","volume":"30 4","pages":"270-274"},"PeriodicalIF":0.9,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13464529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148677434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cisplatin's Silent Toxicity: Hearing Loss, Ethics, and the Nursing Voice.","authors":"Leslie Anne Worona","doi":"10.1188/26.CJON.255-258","DOIUrl":"10.1188/26.CJON.255-258","url":null,"abstract":"<p><p>Cisplatin-induced ototoxicity (CIO) is a serious and underrecognized side effect of chemotherapy that, for various reasons, is often overlooked or omitted from focused care discussions between oncology providers and patients.</p>","PeriodicalId":10350,"journal":{"name":"Clinical journal of oncology nursing","volume":"30 4","pages":"255-258"},"PeriodicalIF":0.9,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13464535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148677396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Colleen Villamin, Jeff Beno, Christine Rudzinski Raby, Jolyn Taylor
{"title":"Enhancing Safety With a Massive Transfusion Protocol for Patients With Cancer Experiencing Uncontrolled Hemorrhage.","authors":"Colleen Villamin, Jeff Beno, Christine Rudzinski Raby, Jolyn Taylor","doi":"10.1188/26.CJON.S2.E88-E95","DOIUrl":"10.1188/26.CJON.S2.E88-E95","url":null,"abstract":"<p><strong>Background: </strong>Oncology nurses can recognize and respond to hemorrhagic emergencies across and beyond cellular therapy care in a timely and efficient manner to promote optimal patient outcomes. Massive transfusion protocol (MTP) is a systematic approach to resuscitating a patient experiencing uncontrolled hemorrhage using a ratio of blood components that mimics whole blood.</p><p><strong>Objectives: </strong>This article provides oncology nurses with a framework for implementing an MTP program to improve response time to hemorrhagic emergencies and reduce patient mortality.</p><p><strong>Methods: </strong>The quality improvement advisory board at a tertiary cancer center approved the initiative to create an institutional MTP program as a clinical framework for clinicians to activate the MTP, delineate team roles and responsibilities, and rapidly transfuse blood components (red blood cells, plasma, and platelets) in a 1:1:1 ratio. Program success was evaluated through quality assurance reviews of each MTP event, with a focus on efficiency metrics and patient outcomes.</p><p><strong>Findings: </strong>Implementation of an MTP program provided a mechanism for immediate availability of blood components in an optimal ratio. Systematic interprofessional MTP event simulations can prepare teams with the clinical skills needed to rapidly resuscitate patients experiencing uncontrolled hemorrhage.</p>","PeriodicalId":10350,"journal":{"name":"Clinical journal of oncology nursing","volume":"30 ","pages":"E88-E95"},"PeriodicalIF":0.9,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martie M Steinfeld, Xiaoxiao Zhang, Ashley Todd, Kathleen L Murphy
{"title":"Lessons Learned: Operationalizing Chimeric Antigen Receptor T-Cell Therapy in the Community Oncology Private Practice Healthcare Setting.","authors":"Martie M Steinfeld, Xiaoxiao Zhang, Ashley Todd, Kathleen L Murphy","doi":"10.1188/26.CJON.S2.E73-E79","DOIUrl":"10.1188/26.CJON.S2.E73-E79","url":null,"abstract":"<p><strong>Background: </strong>Chimeric antigen receptor (CAR) T-cell therapy is an established therapy for relapsed or refractory hematologic malignancies. Traditionally, it has been administered in outpatient or inpatient settings at urban academic medical centers that are affiliated with established stem cell transplantation programs. Tennessee Oncology has successfully treated more than 30 patients with CAR T-cell therapy since August 2024 in the community oncology outpatient setting.</p><p><strong>Objectives: </strong>This article reviews key discoveries and lessons learned in creating a cellular therapy program in a nontraditional setting. Tennessee Oncology approached this endeavor with confidence, not fully understanding the complexity of transitioning from concept to care for the first patient.</p><p><strong>Methods: </strong>Oncology nurses across several roles collaborated, planned, developed, implemented, and educated staff about CAR T-cell therapy across 24 months. The first 12 months were spent without a patient in the program, to assist other facilities in operationalizing their first CAR T-cell therapy program.</p><p><strong>Findings: </strong>Building an institutional CAR T-cell therapy program from inception is a resource-intensive and iterative process; however, successful execution can be achieved through unwavering stakeholder investment and a highly skilled specialized nursing workforce.</p>","PeriodicalId":10350,"journal":{"name":"Clinical journal of oncology nursing","volume":"30 ","pages":"E73-E79"},"PeriodicalIF":0.9,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lacking Policy, Education, and a Plan to Support Bispecific T-Cell Engager Therapy: Nursing-Led Change at an Academic Medical Center.","authors":"Kristin Soper, Lauren M Squires","doi":"10.1188/26.CJON.S2.E40-E45","DOIUrl":"10.1188/26.CJON.S2.E40-E45","url":null,"abstract":"<p><strong>Background: </strong>Many large cancer centers have implemented new policies and procedures to manage patients receiving bispecific T-cell engager (BTCE) therapy.</p><p><strong>Objectives: </strong>A midsize academic center expanded its hematology service, and the institution gained the capacity to offer BTCE therapy and related treatments to patients with a broad range of cancer diagnoses.</p><p><strong>Methods: </strong>The commencement of the BTCE therapy program required nurses to develop expertise in a new specialized treatment option with differing side effects. The team used a multidisciplinary nursing-led approach to understand and implement programs to support the success of BTCE therapy. Prior to this, collaboration and communication among providers, pharmacists, and nurses were lacking, which led to miscommunication and a lack of standardization of processes.</p><p><strong>Findings: </strong>This collaborative, multidisciplinary approach, which included all key stakeholders, demonstrated that effective nurse leadership can promote a culture of excellence.</p>","PeriodicalId":10350,"journal":{"name":"Clinical journal of oncology nursing","volume":"30 ","pages":"E40-E45"},"PeriodicalIF":0.9,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Navigating Acute and Late-Onset Toxicities After Chimeric Antigen Receptor T-Cell Therapy: A Patient-Centered Nursing Approach.","authors":"Karla V Ow","doi":"10.1188/26.CJON.S2.E55-E66","DOIUrl":"10.1188/26.CJON.S2.E55-E66","url":null,"abstract":"<p><strong>Background: </strong>Patients with cancer undergoing advanced therapies, such as chimeric antigen receptor (CAR) T-cell therapy, experience complex treatment-related toxicities that require timely recognition and management. Nurses educate, monitor, and intervene to optimize outcomes and support quality survivorship care for patients.</p><p><strong>Objectives: </strong>This article highlights evidence-based interventions for managing treatment-related complications and outlines strategies to support safe, high-quality care throughout CAR T-cell treatment.</p><p><strong>Methods: </strong>The author conducted a literature review using PubMed®, CINAHL®, and key oncology nursing guidelines to examine relevant studies, guidance, and expert consensus statements to synthesize best practices for nursing assessment and management of immune-based therapy complications.</p><p><strong>Findings: </strong>Clinicians ensure safe and effective care through early toxicity recognition, standardized assessment protocols, and multidisciplinary coordination. Evidence-based interventions, as well as psychological support, contribute to improved patient outcomes. Ongoing education and professional development remain essential.</p>","PeriodicalId":10350,"journal":{"name":"Clinical journal of oncology nursing","volume":"30 ","pages":"E55-E66"},"PeriodicalIF":0.9,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cellular Therapy Nurse Experts as a Conduit Between Hospital Clinical, Business Operations, and Revenue Cycle Teams.","authors":"Claire White","doi":"10.1188/26.CJON.S2.E84-E87","DOIUrl":"10.1188/26.CJON.S2.E84-E87","url":null,"abstract":"<p><strong>Background: </strong>Genetically modified cellular therapies (GMCTs) are increasingly used to treat imminently life-threatening illnesses. However, these therapies are associated with substantial costs, require specialized care, and are available at only a limited number of treatment centers, creating significant barriers to patient access and healthcare delivery.</p><p><strong>Objectives: </strong>The aim of this article is to examine the logistic and financial clearance challenges associated with GMCTs and to highlight the role of nurses in facilitating timely patient access and sustainable therapy delivery.</p><p><strong>Methods: </strong>A descriptive overview was conducted of the financial and operational considerations involved in the administration of GMCTs, with a focus on reimbursement processes, access barriers, and nursing contributions to financial clearance workflows.</p><p><strong>Findings: </strong>The high cost, specialized care requirements, and limited availability of GMCTs create complex logistic and reimbursement challenges that can delay treatment access and threaten the sustainability of therapy delivery. Nurses play a critical role in supporting financial clearance processes, helping to streamline access pathways and optimal reimbursement outcomes for patients receiving cell and gene therapies.</p>","PeriodicalId":10350,"journal":{"name":"Clinical journal of oncology nursing","volume":"30 ","pages":"E84-E87"},"PeriodicalIF":0.9,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nursing Considerations for CAR T-Cell Therapy: Management of Cytokine Release Syndrome and Immune Effector Cell-Associated Neurotoxicity Syndrome.","authors":"Demi M Miller","doi":"10.1188/26.CJON.S2.E67-E72","DOIUrl":"10.1188/26.CJON.S2.E67-E72","url":null,"abstract":"<p><strong>Background: </strong>Chimeric antigen receptor (CAR) T-cell therapy is a promising treatment for certain hematologic malignancies, but many nurses are not trained in caring for two common side effects, cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS).</p><p><strong>Objectives: </strong>This article provides foundational knowledge of CRS and ICANS, including the oncology nurse's role in toxicity monitoring, care coordination, and patient education.</p><p><strong>Methods: </strong>To support safe, evidence-based CAR T-cell therapy administration, this article discusses grading guidelines, nursing assessments, interventions, and education strategies for CRS and ICANS.</p><p><strong>Findings: </strong>Nurses serve a key role in mitigating CRS and ICANS through early recognition, continuous monitoring, therapeutic intervention, and patient and caregiver education. Using standardized protocols, frequently monitoring vital signs, and performing neurologic assessments optimize patient safety and outcomes.</p>","PeriodicalId":10350,"journal":{"name":"Clinical journal of oncology nursing","volume":"30 ","pages":"E67-E72"},"PeriodicalIF":0.9,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of the Nurse Coordinator in Hemophilia Gene Therapy.","authors":"Michelle Cha","doi":"10.1188/26.CJON.S2.E80-E83","DOIUrl":"10.1188/26.CJON.S2.E80-E83","url":null,"abstract":"<p><strong>Background: </strong>Since the 1990s, clinical trials have studied the feasibility, safety, efficacy, and challenges of using gene therapy to cure hemophilia. In 2022, the U.S. Food and Drug Administration approved the first commercially available gene therapy treatment for hemophilia.</p><p><strong>Objectives: </strong>The purpose of this article is to examine the nurse coordinator's role in educating patients, preparing them for treatment, and providing comprehensive short- and long-term follow-up at a hemophilia treatment center.</p><p><strong>Methods: </strong>Relevant literature, U.S. Food and Drug Administration package inserts, and clinical practice related to hemophilia gene therapy were reviewed. Discussion regarding psychosocial implications and interdisciplinary care were examined and synthesized into this article.</p><p><strong>Findings: </strong>Hemophilia gene therapy expands on the existing hemophilia teatment center comprehensive care model. The gene therapy center of excellence framework highlights the importance of care coordination, patient education, psychosocial support, and interdisciplinary collaboration. The nurse coordinator role serves as liaison, advocate, and educator for patients and other clinicians.</p>","PeriodicalId":10350,"journal":{"name":"Clinical journal of oncology nursing","volume":"30 ","pages":"E80-E83"},"PeriodicalIF":0.9,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}