CHRISMED Journal of Health and Research最新文献

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Effect of antiretroviral therapy on lipid profile in newly diagnosed HIV-infected children of immune stage III and IV 抗逆转录病毒疗法对新诊断的免疫III期和IV期HIV感染儿童脂质状况的影响
CHRISMED Journal of Health and Research Pub Date : 2022-07-01 DOI: 10.4103/cjhr.cjhr_93_21
Neelam Singh, Vijendra Garg, Rohitash Meena, Rambabu Sharma, S. Gothwal
{"title":"Effect of antiretroviral therapy on lipid profile in newly diagnosed HIV-infected children of immune stage III and IV","authors":"Neelam Singh, Vijendra Garg, Rohitash Meena, Rambabu Sharma, S. Gothwal","doi":"10.4103/cjhr.cjhr_93_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_93_21","url":null,"abstract":"Background: There are increasing concerns about the adverse effects of highly active antiretroviral therapy (HAART) on lipid profiles. Limited studies reported the adverse effects of HAART on lipid profiles from the Indian subcontinent. Methods: This observational study was conducted at a tertiary care hospital in North Western India. The objective of the study was to find out the adverse effects on lipid profiles after HAART initiation in newly diagnosed HIV-infected children of immune stage III and IV in the 18 months to 16 year age group. These 43 children were evaluated every 3 months for lipid profile for 1 year. Results: There was a nonsignificant increase in total lipid and phospholipid levels and a statistically significant increase in triglycerides (TGs), cholesterol, low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL) levels after initiation of HAART therapy and a statistically significant decline in high-density lipoprotein (HDL) level after initiation of HAART therapy in immune phase III. The mean level of total lipid profile, phospholipids, cholesterol, HDL, LDL, VLDL, and TGs before starting of treatment was 474 mg/dl, 147 mg/dl, 126.8 mg/dl, 44.7 mg/dl, 94.3 mg/dl, 22.9 mg/dl, and110 mg/dl in immune stage IV, respectively. After starting treatment, the mean level of total lipid profile, phospholipids, cholesterol, HDL, LDL, VLDL, and TGs was 495.7 mg/dl, 164 mg/dl, 146.5 mg/dl, 38.9 mg/dl, 108.5 mg/dl, 28.9 mg/dl, and 127.3 mg/dl in immune stage IV, respectively. There was a statistically significant increase in total lipid, TG, phospholipid, cholesterol, LDL, and VLDL levels. There was a statistically significant decline in HDL level after initiation of HAART therapy in immune stage IV. Conclusions: We concluded that there was a significant alteration in lipid profile in HIV-infected children of immune stage III and IV with HAART.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"159 - 163"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48991812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fosfomycin susceptibility among multidrug resistant and extended spectrum β-Lactamase producing uropathogenic Escherichia coli isolates at a tertiary care hospital of Western India 西印度一家三级医院多药耐药性和产β-内酰胺酶的尿路致病性大肠杆菌对磷霉素的敏感性
CHRISMED Journal of Health and Research Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_21_21
R. Jain, N. Pal, S. Hooja
{"title":"Fosfomycin susceptibility among multidrug resistant and extended spectrum β-Lactamase producing uropathogenic Escherichia coli isolates at a tertiary care hospital of Western India","authors":"R. Jain, N. Pal, S. Hooja","doi":"10.4103/cjhr.cjhr_21_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_21_21","url":null,"abstract":"Introduction: Urinary tract infections are mostly treated empirically with broad-spectrum antibiotics which have resulted in development of multi-drug resistant strains. Limited options of newer antibiotics have necessitated the reintroduction of some old antimicrobial agents such as fosfomycin. Aim: To evaluate the in-vitro activity of fosfomycin against uropathogenic E.coli. Method: A total of 145 E.coli isolates were identified by conventional microbiological procedures and antimicrobial susceptibility performed by Kirby-Bauer disk diffusion method. They were screened for extended spectrum β-lactamase (ESBL) production and screen positives were confirmed by phenotypic confirmatory test (CLSI). Results: Out of 145 isolates, 91 (62.76 %) were found in males and 54 (37.24%) from females. Majority of the isolates were detected in the age group of 21-30 years 48.96%. A very high susceptibility of 94.48% was observed with fosfomycin. Suceptibility to tigecycline and nitrofurantoin was 87.58 % and 77.24 % respectively. Multi-drug resistance was observed in 85.51% isolates and 45.51% were ESBL producers. Conclusion: Fosfomycin showed an excellent in vitro activity against MDR and ESBL producing E.coli, therefore it should be considered as a potential therapeutic alternative in the treatment of UTI.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"125 - 129"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46930308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SARS-CoV-2-related multisystem inflammatory syndrome in children and adolescents 儿童和青少年sars - cov -2相关多系统炎症综合征
CHRISMED Journal of Health and Research Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_71_21
Arpita Gupta
{"title":"SARS-CoV-2-related multisystem inflammatory syndrome in children and adolescents","authors":"Arpita Gupta","doi":"10.4103/cjhr.cjhr_71_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_71_21","url":null,"abstract":"","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"105 - 106"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43726499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leishmanial lymphadenopathy in a native patient from the nonendemic region of Himachal Pradesh, India 印度喜马偕尔邦非流行区一名本地患者的利什曼原虫淋巴结病
CHRISMED Journal of Health and Research Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_87_21
R. Raina, Shubham Sharma, N. Verma, Meghavath Bai, Ritika Kashyap, S. Raina
{"title":"Leishmanial lymphadenopathy in a native patient from the nonendemic region of Himachal Pradesh, India","authors":"R. Raina, Shubham Sharma, N. Verma, Meghavath Bai, Ritika Kashyap, S. Raina","doi":"10.4103/cjhr.cjhr_87_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_87_21","url":null,"abstract":"A case of leishmanial lymphadenopathy in an immunocompetent native from a nonendemic area of the Ravi River valley area (altitude 996 m above the mean sea level) of Chamba, Himachal Pradesh, India, is reported. Diagnosis of visceral leishmaniasis by demonstration of Leishman–Donovan bodies in lymph nodes by fine-needle aspiration cytology has been rarely reported.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"140 - 142"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42969017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A randomized controlled trial of lidocaine versus ropivacaine for pain relief after episiotomy 利多卡因与罗哌卡因缓解会阴切开术后疼痛的随机对照试验
CHRISMED Journal of Health and Research Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_88_20
Asis Adhikary, Papiya Biswas, T. Mondal, S. Bhattacharyya
{"title":"A randomized controlled trial of lidocaine versus ropivacaine for pain relief after episiotomy","authors":"Asis Adhikary, Papiya Biswas, T. Mondal, S. Bhattacharyya","doi":"10.4103/cjhr.cjhr_88_20","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_88_20","url":null,"abstract":"Introduction: Episiotomy is the most common surgical procedure for parturient. Analgesia after episiotomy has received less attention, though the postepisiotomy pain may hamper the day-to-day activities such as sitting, sleeping, urinating, and walking of the parturient. It is desirable to reduce the postepisiotomy pain as early as possible. Therefore, we planned to carry out a randomized controlled trial to compare the safety and efficacy of lidocaine versus ropivacaine perineal infiltration for pain relief after episiotomy. Materials and Methods: The prospective randomized controlled trial was conducted in the Department of Obstetrics and Gynaecology of R. G. Kar Medical College and Hospital, Kolkata. One hundred women were enrolled and randomized into the two groups: Lidocaine infiltration group and ropivacaine infiltration group. Primary objective was to evaluate the efficacy of postepisiotomy pain control by the visual analog scale (VAS) score at 24 h after the episiotomy. Secondary objectives were to evaluate the efficacy of postepisiotomy pain control by VAS score during suturing, at 2 h and 48 h or any adverse effects and maternal satisfaction at 48 h. Results: The postepisiotomy pain relief at 2 h and 24 h was significantly lower in ropivacaine in comparison to lidocaine infiltration. Mean VAS Score 24 h after suturing in lidocaine group was 6.38, and in ropivacaine group, it was 5.64. Maternal pain perception at the time of suturing and at 48 h was also less in ropivacaine than in lidocaine infiltration. Mothers were more satisfied with ropivacaine drug. Conclusion: The present study showed that there was definite improvement of postepisiotomy pain relief at 2 h and 24 h in ropivacaine local infiltration of the episiotomy wound in comparison to lidocaine infiltration and mothers were more satisfied with ropivacaine use.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"130 - 134"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46670170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strengthening of health care and local production of medicines and other health technologies to improve access and affordability 加强医疗保健和药品及其他卫生技术的当地生产,以提高获取和负担能力
CHRISMED Journal of Health and Research Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_83_21
Abhijit V. Boratne, M. Murugan, Senkadhirdasan Dakshinamurthy
{"title":"Strengthening of health care and local production of medicines and other health technologies to improve access and affordability","authors":"Abhijit V. Boratne, M. Murugan, Senkadhirdasan Dakshinamurthy","doi":"10.4103/cjhr.cjhr_83_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_83_21","url":null,"abstract":"A lot of discussion happened regarding the required World Health Organization's support to strengthen local production of drugs in this pandemic. During the COVID-19 pandemic, the world has struggled for everything starting from the availability of masks, personal protective equipment's, medicines, equipment, ventilators, and even basic oxygen. All these needs have exposed the existing condition of our health-care system that has called for improving the infrastructure and workforce at the earliest. Health-care spending and its impact on economic performance are vital to be seen leading to an increase in gross domestic product and vice versa. A recent estimate states that our country which was told as world's pharmacy is now facing a shortage of vaccines doses. A recent estimate states that our country which was told as world's pharmacy is now facing a shortage of vaccines doses creating the necessary research and development to discover or develop innovative way of strengthening the local production of medicines. The Ministry of Health and Family Welfare in India has initiated several measures to ensure the quality of drugs available in India. Lower- and middle-income countries face macroeconomic vulnerabilities, high levels of poverty and are lagging behind the universal health coverage. Hence, necessary recommendations were arrived for these issues in this article.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"112 - 117"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49488385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malaria and dengue coinfection 疟疾和登革热合并感染
CHRISMED Journal of Health and Research Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_62_21
Amandeep Kaur, Monika Sharma
{"title":"Malaria and dengue coinfection","authors":"Amandeep Kaur, Monika Sharma","doi":"10.4103/cjhr.cjhr_62_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_62_21","url":null,"abstract":"Concurrent infection of malaria and dengue may be difficult to diagnose because of overlapping signs and symptoms. An 11-year-old boy presenting in the causality with blanching rash, respiratory distress, and hypotension was initially managed as dengue shock syndrome. Due to high-grade fever and hepatosplenomegaly, peripheral blood film for malarial parasite was sent, which came out to be positive for vivax malaria. This case report emphasizes the need to consider about the possibility of dengue–malaria coinfection in the endemic areas and highlights the challenges related to management among these patients.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"143 - 145"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47689321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lock to unlock: A multidimensional impact of COVID-19 in India 锁定解锁:新冠肺炎对印度的多层面影响
CHRISMED Journal of Health and Research Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_82_21
M. Mageshwari, Abhijit Vinodrao
{"title":"Lock to unlock: A multidimensional impact of COVID-19 in India","authors":"M. Mageshwari, Abhijit Vinodrao","doi":"10.4103/cjhr.cjhr_82_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_82_21","url":null,"abstract":"The COVID-19 pandemic forced for first lockdown in India in March 2020. Resurgence of COVID-19 cases has forced many states in India to reintroduce the movement restrictions in March 2021. With four times increase in number of cases, many hospitals are swamped with patients, shortage of doctors and healthcare workers, shortage of personal protective equipment (PPEs), medications, and oxygen. The second wave led to out of pocket expenditures, hike in health care budget, burnouts among the health care workers (HCWs), migration, and hampered education system. The crisis was due to insufficient oxygen and beds, repeated changes in the treatment protocol and testing strategies, violence against HCWs and front line workers (FLWs), vaccination hesitancy to vaccination shortage, and increased morbidity to mortality. The quarantine and isolation of HCWs and FLWs become difficult due to the insufficient workforce. This formed as an opportunity leading to public–private partnership for patient care and successful vaccination. The pandemic brought the concept of advanced technologies and inventions such as use of Robotics, Apps such as Arogyasetu and CoWin, Ventilators, and O2 plants (O2 concentrator), and self-testing kits (COVISELF). Apart from the COVID appropriate behaviors, mass vaccination and newly approved treatments, the policymakers can stabilize the country with helping hand from industries, development of workforce, adequate production, and supply of medicines-vaccine and PPEs to rejuvenate the healthcare industry at the earliest.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"107 - 111"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49339231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Duties, responsibilities, and challenges of community health workers: Evidence from a health block of northern Indian province 社区卫生工作者的职责、责任和挑战:来自印度北部省份卫生区的证据
CHRISMED Journal of Health and Research Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_35_21
Ramesh Rattu, Manoj Kumar, K. Sekhri, Ankit Chaudhary
{"title":"Duties, responsibilities, and challenges of community health workers: Evidence from a health block of northern Indian province","authors":"Ramesh Rattu, Manoj Kumar, K. Sekhri, Ankit Chaudhary","doi":"10.4103/cjhr.cjhr_35_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_35_21","url":null,"abstract":"Introduction: Accredited Social Health Activist (ASHA) worker is a significant frontline health worker that acts as a link between community and health services and helps delivering quality health services to vulnerable section of the society. The present study was conducted with an objective to explore the duties and responsibilities of the ASHA worker along with obstacles faced by them while discharging their duties. Methods: It was a cross-sectional study including 150 ASHA workers of a health block in Himachal Pradesh. Data were collected using a semi-structured questionnaire consisting of six subsections dedicated to different dimensions related to ASHA workers. Results: Majority of ASHAs stated that their job had a positive effect on their social relationships, confidence as well as their physical and mental health. About two-thirds workers failed to fulfill targets due to many activities running simultaneously. About 43.3% felt mental stress during the job and 20.7% workers experienced harassment by hospital staff. About 40% stated that they had received unsatisfactory training. Toilet facility was available for only 59.3% workers and safe drinking water for 64.7% ASHAs. Only 4.7% of ASHAs were satisfied with their monthly income. Conclusion: While ASHAs are working with dedication in the field, still they are experiencing many problems associated with their personal life, community norms, terrain of the workplace, transportation, and organizational issues. The study recommends few amendments as ASHAs being an integral part of Indian health system must be given their due consideration so that the vision of universal health coverage and sustained development can be attained effectively.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"135 - 139"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47803836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experiential teaching learning of humanities in health professions education 健康职业教育中的人文体验式教学
CHRISMED Journal of Health and Research Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_161_20
Anushi Mahajan, P. Bhagat, Sudhir Babu, A. Singhal, D. Badyal, R. Mahajan
{"title":"Experiential teaching learning of humanities in health professions education","authors":"Anushi Mahajan, P. Bhagat, Sudhir Babu, A. Singhal, D. Badyal, R. Mahajan","doi":"10.4103/cjhr.cjhr_161_20","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_161_20","url":null,"abstract":"Humanities are an integral part of health professions. However, with educational focus shifting gradually toward knowledge, information, evidence-based medicine, and technology, it has taken a back seat and become a part of the “hidden curriculum.” Humanities are hardly ever taught upfront to students of the health profession, let alone its assessment. With the need of its inclusion in health professional education now recognized and established through competency-based education, we need to be aware of the tools and strategies which can be used to teach and assess it. In this article, we share selected tools with relevant readily usable examples for teaching humanities to students of the health profession. Faculty may find it useful to plan sessions around related competencies. Incorporation of such experiential teaching and learning methods can help us achieve the transition from “high-tech” to “high touch” health professions education.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"118 - 124"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47612807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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