Circulation. Arrhythmia and electrophysiology最新文献

{"title":"Managing Oversensing in Extravascular ICDs: Lessons From Clinical Experience.","authors":"Pierre Bordachar, Marc Strik, Romain Eschalier, Anand Thiyagarajah, F Daniel Ramirez, Sylvain Ploux","doi":"10.1161/CIRCEP.125.014071","DOIUrl":"10.1161/CIRCEP.125.014071","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e014071"},"PeriodicalIF":9.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144706562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Latent Effects of Wildfire Particulate Matter on Resting Heart Rate Measured With Wearable Devices.","authors":"So-Min Cheong, Marco Perez, Youn Soo Jung, Brian Kim, Kari Nadeau","doi":"10.1161/CIRCEP.125.013836","DOIUrl":"10.1161/CIRCEP.125.013836","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013836"},"PeriodicalIF":9.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144706560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prompt Identification of the Location of Gap Conduction in the Mitral Isthmus Following Vein of Marshall Ethanol Infusion and Endocardial Ablation.","authors":"Qiaoyuan Li, Yanguang Li, Zhuo Liang, Tao Zhang, Xu Liu, Dongping Fang, Jin Bai, Jian Li, Fengxiang Zhang, Yunlong Wang","doi":"10.1161/CIRCEP.124.013454","DOIUrl":"10.1161/CIRCEP.124.013454","url":null,"abstract":"<p><strong>Background: </strong>Mitral isthmus (MI) gap conduction is common despite ethanol infusion into the vein of Marshall (EI-VOM) and endocardial ablation of the MI. This study aimed to investigate the characteristics of electrograms of the distal coronary sinus (CSd) to guide the identification of the gap location in the MI.</p><p><strong>Methods: </strong>A total of 187 patients who underwent EI-VOM and MI ablation were included in the study. After routine completion of EI-VOM and endocardial MI ablation, the characteristics of the electrogram in the CSd during left atrial appendage pacing were analyzed in unblocked MI conduction.</p><p><strong>Results: </strong>Among the 187 patients, 43.3% (81/187) had unblocked MI following EI-VOM and linear lesion creation in the endocardium. In patients with unblocked MI, 84.0% (68/81) showed double potentials in the CSd during left atrial appendage pacing, among whom 80.9% (55/68) presented with an earlier high-frequency near-field potential followed by a low-frequency far-field potential, suggesting an epicardial gap, whereas 19.1% (13/68) presented with a far-field potential followed by a near-field potential, suggesting an endocardial gap. In patients with single potentials in the CSd (16.0%, n=13), simple activation mapping of the endocardium and CSd revealed the gap location. Intracoronary sinus ablation was necessary in 77.8% (63/81) of the patients, with a mean of 1.3±1.7 sites and 1.1±0.4 minutes of ablation. Eventually, 95.7% (179/187) of the patients achieved MI block. These findings were confirmed in an external validation cohort, which demonstrated the effectiveness and efficiency of CSd potential-guided gap identification.</p><p><strong>Conclusions: </strong>The characteristics of the electrograms in the CSd could aid in the prompt identification of the gap location(s) in the MI in patients with unblocked MI conduction.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013454"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How a Topological Mindset May Offer Extra Control During Mapping and Ablation of Left-Sided Reentrant Atrial Tachycardia.","authors":"Mattias Duytschaever, Maarten De Smet, Jordi Martens, Milad El Haddad, Benjamin De Becker, Clara Francois, Rene Tavernier, Robin Van den Abeele, Sander Hendrickx, Nele Vandersickel, Jean-Benoit Le Polain de Waroux, Sebastien Knecht","doi":"10.1161/CIRCEP.125.013780","DOIUrl":"10.1161/CIRCEP.125.013780","url":null,"abstract":"<p><strong>Background: </strong>Reentry (macro or localized) is historically described as multiple pathways that are separated by barriers (either anatomic or functional) and involve active and passive loops (identified by electro-anatomic and entrainment mapping, EAM/ETM). Some reentrant atrial tachycardia (AT) cases are characterized by challenging activation patterns and unexpected ablation responses. A recent translational study, focusing on topology (TOP) and the role of boundaries, suggests that thinking topology within EAM/ETM might offer extra control during mapping and ablation of reentrant AT. We aimed to propose and prospectively validate a workflow (EAM/ETM+TOP) in which we integrate topological thinking within an EAM/ETM workflow for mapping and ablation of left-sided (left atrium) AT.</p><p><strong>Methods: </strong>The integrated workflow was performed in 88 left atrium reentrant AT cases. After EAM/ETM, the number of loops and potential ablation strategy were verified against the number of critical and noncritical boundaries (critical boundary [CB], non-CB). Linear radiofrequency lesions were deployed to connect both CBs, preferably by one direct CB-CB line.</p><p><strong>Results: </strong>EAM/ETM+TOP-based mapping was feasible in all cases and led to a diagnosis of a 2B topology with single-loop activation in 33 cases and a≥3B topology with dual-loop activation in 55 cases. In 87 out of 88 cases, subsequent ablation via a direct CB-CB approach (n=75), an indirect CB-non-CB-CB (n=9), or an indirect CB-non-CB-non-CB-CB approach (n=3) led to successful termination of AT. No unexpected changes in tachycardia cycle length occurred. After a median follow-up of 356 (inter-quartile range, 228-537) days, 16 patients experienced recurrence of AT (18%).</p><p><strong>Conclusions: </strong>Thinking topology within an EAM/ETM workflow may offer extra control during mapping and ablation of left-sided reentrant AT.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013780"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144282635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Atrial Remodeling Drives Arrhythmia in Fabry Disease.","authors":"Ashwin Roy, Christopher O'Shea, Albert Dasí, Leena Patel, Max J Cumberland, Daniel Nieves, Hansel S Canagarajah, Sophie Thompson, Amar Azad, Anna M Price, Caitlin Hall, Amor Mia B Alvior, Phalguni Rath, Ben Davies, Blanca Rodriguez, Andrew P Holmes, Davor Pavlovic, Jonathan N Townend, Tarekegn Geberhiwot, Katja Gehmlich, Richard P Steeds","doi":"10.1161/CIRCEP.124.013352","DOIUrl":"10.1161/CIRCEP.124.013352","url":null,"abstract":"<p><strong>Background: </strong>Fabry disease (FD) is an X-linked lysosomal storage disorder caused by α-Gal A (α-galactosidase A) deficiency, resulting in multiorgan accumulation of sphingolipid, namely globotriaosylceramide. This triggers ventricular myocardial hypertrophy, fibrosis, and inflammation, driving arrhythmia and sudden death. Atrial fibrillation is common, yet the cellular mechanisms accounting for this are unknown.</p><p><strong>Methods: </strong>To address this, we conducted ECG analysis from a large cohort of 115 adults with FD at varying cardiomyopathy stages. ECG P-wave characteristics were compared with non-FD controls. Cellular contractile and electrophysiological function were examined in a novel atrial cellular FD model developed and imputed into in silico atrial models to provide insight into mechanisms of arrhythmia. Induced pluripotent stem cells were genome-edited using Clustered Regularly Interspaced Short Palindromic Repeats-Cas9 to introduce the <i>GLA</i> p.<i>N215S</i> variant and differentiated into induced pluripotent stem cell-derived atrial cardiomyocytes (iPSC-CMs). Contraction, calcium handling, and electrophysiology experiments were conducted. Bi-atrial in silico models were developed with cellular changes as in <i>GLA</i> p.<i>N215S</i> iPSC-CMs.</p><p><strong>Results: </strong>ECG analysis demonstrated P-wave duration and PQ interval shortening in FD adults before the onset of cardiomyopathy. Patients with FD exhibited a higher incidence of premature atrial contractions and increased risk of atrial fibrillation compared with healthy controls. <i>GLA</i> p.<i>N215S</i> iPSC-CMs were deficient in α-Gal A and exhibited globotriaosylceramide accumulation. Atrial <i>GLA</i> p.<i>N215S</i> iPSC-CMs demonstrated a more positive diastolic membrane potential, faster action potential upstroke velocity, greater incidence of delayed afterdepolarizations, greater contraction force, and alterations in calcium handling compared with wild-type iPSC-CMs. Simulations with these changes in the in silico models resulted in similar P-wave morphology changes to those seen in early FD cardiomyopathy and increased atrial fibrillation vulnerability.</p><p><strong>Conclusions: </strong>These findings provide novel insights into underpinning mechanisms for atrial arrhythmia and a rationale for early P-wave changes in FD. These may be targeted to develop therapeutic strategies to reduce the arrhythmic burden in FD.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013352"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7617850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of Machine Learned Intracardiac Electrograms to Predict Postinfarction Ventricular Scar Topography.","authors":"Kasun De Silva, Timothy G Campbell, Richard G Bennett, Samual Turnbull, Ashwin Bhaskaran, Robert D Anderson, Christopher Davey, Alexandra K O'Donohue, Aaron Schindeler, Dinesh Selvakumar, Yasuhito Kotake, Chi-Jen Hsu, James J H Chong, Eddy Kizana, Saurabh Kumar","doi":"10.1161/CIRCEP.124.013611","DOIUrl":"10.1161/CIRCEP.124.013611","url":null,"abstract":"<p><strong>Background: </strong>Accurate delineation of scar patterns is valuable for guiding catheter ablation of ventricular tachycardia. We hypothesized that scar and its pattern of distribution can be determined from intracardiac electrograms using computational signal processing and that further improvements in classification can be achieved with a convolutional neural network.</p><p><strong>Methods: </strong>A total of 5 sheep underwent anteroseptal infarction (plus 1 healthy control) with electroanatomic mapping (129±12 days post-infarct). A whole-heart histological model of the postinfarction scar was created and coregistered to ventricular electrograms. Electrograms were matched to scar pattern categories; no scar, at least endocardial scar: at least intramural scar (intramural scar sparing the endocardium), or epicardial-only scar (epicardial scar sparing the endocardium/intramural space). A suite of signal-processing features was extracted from bipolar electrograms. Furthermore, bipolar and unipolar electrograms were used to train a time series convolutional neural network (InceptionTime).</p><p><strong>Results: </strong>A total of 11 551 electrograms were matched to 451 biopsies. Bipolar and unipolar voltage alone were poor classifiers of scar patterns. For each of the scar labels, 20 bipolar electrogram features (predominantly within the frequency domain) yielded an area under the curve of 0.815, 0.810, 0.704, and 0.681 to predict no scar, at least endocardial scar, at least intramural scar, and epicardial-only scar, respectively. Substantial improvement was achieved with a convolutional neural network trained on unipolar electrograms: areas under the curve and accuracy (averaged across wavefronts) were 0.977 and 0.929 for no scar, 0.970 and 0.919 for at least endocardial scar, 0.909 and 0.959 for at least intramural scar and 0.926 and 0.958 for epicardial-only scar.</p><p><strong>Conclusions: </strong>Convolutional neural network-derived analysis of unipolar electrogram data has excellent predictive value for determination of scar patterns. Computational analyses of electrogram data beyond voltage and other time-domain features are necessary to improve the identification of arrhythmogenic sites in the ventricle.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013611"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144282725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wearable Irregular Heart Rhythm Detection Recurrences and Electrocardiographic Atrial Fibrillation Confirmation: The Fitbit Heart Study.","authors":"Steven A Lubitz, Michael V McConnell, Caitlin Selvaggi, Aparna Krishnamoorthy, Steven J Atlas, David D McManus, Sherry Pagoto, Daniel E Singer, Alexandros Pantelopoulos, Andrea S Foulkes, Anthony Z Faranesh","doi":"10.1161/CIRCEP.124.013565","DOIUrl":"10.1161/CIRCEP.124.013565","url":null,"abstract":"<p><strong>Background: </strong>Wrist-worn wearables can detect irregular heart rhythms using photoplethysmography, but ECGs are required to confirm atrial fibrillation (AF). We sought to determine the frequency of a recurrent irregular heart rhythm detection (IHRD; ≥30 minutes of an irregular rhythm), estimate the potential diagnostic yield of different electrocardiographic monitoring strategies for confirming AF, and identify predictors of recurrent IHRDs.</p><p><strong>Methods: </strong>The Fitbit Heart Study enrolled wrist-worn photoplethysmography device users without diagnosed AF. Of 455 699 participants, 1057 who wore and returned a 1-week ECG patch monitor after receiving an IHRD were analyzed. Baseline clinical data, device-derived metrics, IHRDs during follow-up, and electrocardiographic patch data were used for analysis.</p><p><strong>Results: </strong>A total of 570 (53.9%) participants were aged 40 to 64 years, 422 (39.9%) were aged ≥65 years, and 510 (48.2%) were women. Median follow-up after ECG patch initiation was 80 days (interquartile range, 45-122 days). The frequency of another IHRD was 57.2% (95% CI, 53.1%-60.9%) at 3 months. After an initial IHRD, the estimated diagnostic yield for AF with a 10-second ECG was 7.6% (95% CI, 6.2%-9.0%), twice-daily 30-second ECGs over 1 week 19.0% (95% CI, 16.7%-21.2%), 24-hour monitor 17.4% (95% CI, 15.5%-19.3%), 1-week monitor 32.2% (95% CI, 29.4%-35.0%), 2-week monitor 46.8% (95% CI, 42.7%-50.8%), and 4-week monitor 60.8% (95% CI, 56.5%-65.1%). The risk of a recurrent IHRD was greater with older age (<i>P</i><0.001), male sex (<i>P</i>=0.001), vascular disease (<i>P</i>=0.03), longer initial runs of consecutive IHRDs at detection (<i>P</i>=0.02), and less nightly sleep (<i>P</i>=0.03).</p><p><strong>Conclusions: </strong>Irregular heart rhythms are common after initial detection using a wrist-worn wearable device. Longer electrocardiographic monitoring periods increase the likelihood of confirming AF.</p><p><strong>Registration: </strong>URL: https://www.clinicaltrials.gov; Unique identifier: NCT04380415.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013565"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12263307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimal Hemolytic Profile of the Monopolar Lattice-Tip Pulse Field Ablation System: An In Vivo Preclinical Porcine Assessment.","authors":"Keita Watanabe, Moritz Nies, Daniel C Sigg, Lars Mattison, Paul Hultz, Vivek Y Reddy, Jacob S Koruth","doi":"10.1161/CIRCEP.125.013787","DOIUrl":"10.1161/CIRCEP.125.013787","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013787"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Race Comparisons in Patients With Cardiac Sarcoidosis: Insights From the Cardiac Sarcoidosis Consortium.","authors":"Angkawipa Trongtorsak, Junior De La Rosa Martinez, Thomas C Crawford, Frank M Bogun, Xiaokui Gu, Eric Puroll, Kenneth A Ellenbogen, Alexandru B Chicos, Henri Roukoz, Peter J Zimetbaum, Steven J Kalbfleisch, Francis D Murgatroyd, David A Steckman, Lynda E Rosenfeld, Kyoko Soejima, Adarsh K Bhan, Vasanth Vedantham, Timm-Michael L Dickfeld, David B DeLurgio, Pyotr G Platonov, Matthew M Zipse, Suguru Nishiuchi, Matthew L Ortman, Calambur Narasimhan, Kristen K Patton, David G Rosenthal, Siddharth S Mukerji, Jarieke C Hoogendoorn, Katja Zeppenfeld, Mikhail Torosoff, Marc A Judson, Katherine Martin, Christopher Madias, Melody Hermel, Khaled Nour, Estelle Torbey, William H Sauer, Jordana Kron","doi":"10.1161/CIRCEP.124.013670","DOIUrl":"10.1161/CIRCEP.124.013670","url":null,"abstract":"<p><strong>Background: </strong>Differences in cardiac sarcoidosis between racial groups remain understudied. Therefore, this study aims to explore race differences in patients with cardiac sarcoidosis.</p><p><strong>Methods: </strong>We analyzed data from the Cardiac Sarcoidosis Consortium, an international registry including over 25 centers. The primary clinical outcome was a composite end point of all-cause mortality, left ventricular assist device implantation, heart transplantation, or implantable cardioverter defibrillator therapy.</p><p><strong>Results: </strong>A total of 619 patients were included in the study (362 White, 193 Black, and 64 other races). Black patients were diagnosed with cardiac sarcoidosis at a younger age (50.5±11.8 versus 53.7±10.5 years old; <i>P</i>=0.010) compared with White patients. Left ventricular ejection fraction was significantly lower in Black patients (44.6±15.4 versus 48.3±14.0; <i>P</i>=0.008). In addition, extracardiac involvement in the lungs (80.3% versus 72.7%; <i>P</i>=0.046), skin (22.8% versus 12.4%; <i>p</i>=0.002), and eyes (13.5% versus 5.5%; <i>P</i>=0.001) was more prevalent in Black patients. Patients had significantly higher rates of hypertension (69.9% versus 50.6%; <i>P</i><0.001), diabetes (37.8% versus 21.0%; <i>P</i><0.001), smoking (40.9% versus 26.8%; <i>P</i><0.001), chronic obstructive pulmonary disease or emphysema (15.5% versus 4.1%; <i>P</i><0.001), and chronic kidney disease (25.9% versus 12.4%; <i>P</i><0.001). The treatment patterns including glucocorticoid (71% versus 74.3%; <i>P</i>=0.4), glucocorticoid-sparing (53.4% versus 59.9%; <i>P</i>=0.14), and implantable cardioverter defibrillator or cardiac resynchronization implantation (75.6% versus 73.8%; <i>P</i>=0.63), were similar. No significant differences were found in the primary outcome (29.5% in Black versus 28.5% in White; <i>P</i>=0.79). Subgroup analysis of the primary outcome also revealed no significant differences in both the left ventricular ejection fraction >35% group (24.1% in Black versus 25.9% in White; <i>P</i>=0.72) and the left ventricular ejection fraction ≤35% group (51% versus 42.5%; <i>P</i>=0.35).</p><p><strong>Conclusions: </strong>Black patients with cardiac sarcoidosis exhibited significantly higher rates of lung, skin, and eye involvement and comorbidities, but had similar cardiac clinical outcomes and all-cause mortality compared with White patients. Nonetheless, ascertainment bias cannot be excluded.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013670"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12263308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-World Safety Profile of the Extravascular (EV) Implantable Defibrillator System: Insights From the MAUDE Database.","authors":"Anish S Shah, Marc Engels, Roger A Freedman, H Immo Lehmann, Klitos Konstantinidis, Ravi Ranjan, T Jared Bunch","doi":"10.1161/CIRCEP.125.013831","DOIUrl":"10.1161/CIRCEP.125.013831","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013831"},"PeriodicalIF":9.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}