Zhen Zhou, Hanyu Zhang, Hongbo Xiong, Ke-Qiong Deng, Meng Zheng, Yongkang Zhang, Zhendong Xu, Ruifeng Tian, Tong Zhang, Xiangjie Kong, Yingying Hu, Yinhua Luo, Huanhuan Cai, Di Fan, Qing K Wang, Bo He, Qiongxin Wang, Zhibing Lu
{"title":"Inhibition of Satellite Glial Cell Activation in Stellate Ganglia Prevents Ventricular Arrhythmogenesis and Remodeling After Myocardial Infarction.","authors":"Zhen Zhou, Hanyu Zhang, Hongbo Xiong, Ke-Qiong Deng, Meng Zheng, Yongkang Zhang, Zhendong Xu, Ruifeng Tian, Tong Zhang, Xiangjie Kong, Yingying Hu, Yinhua Luo, Huanhuan Cai, Di Fan, Qing K Wang, Bo He, Qiongxin Wang, Zhibing Lu","doi":"10.1161/CIRCEP.125.013866","DOIUrl":"https://doi.org/10.1161/CIRCEP.125.013866","url":null,"abstract":"<p><strong>Background: </strong>Hyperactivity of sympathetic neurons in the stellate ganglia (SG) contributes to ventricular arrhythmias and remodeling postmyocardial infarction (MI). However, the role of satellite glial cells (SGCs) surrounding the neurons in this process remains unknown.</p><p><strong>Methods: </strong>SGC-specific chemogenetic manipulation was locally applied to modulate SG-SGC activity dual-directionally in the rats with naïve or infarcted hearts. Subsequently, cardiac sympathetic neural activity and ventricular electrophysiological stability in response to stimulation were evaluated, as well as cardiac neural and structural remodeling post-MI. SG bulk RNA sequencing and the interaction between SGCs and sympathetic neurons isolated from SG were used to explore the underpinning mechanisms.</p><p><strong>Results: </strong>SG-SGC excitation increased SG neural activity and ventricular electrophysiological instability in rats with naïve hearts, whereas its inhibition influenced none of the above under physiological conditions. Of note, 2-hour-MI provoked SG-SGC activation that positively correlated with cardiac sympathetic neurotransmitter (norepinephrine) release. Accordingly, SGC activation in the SG enhanced cardiac sympathetic hyperactivity 2 hours post-MI, whereas SG-SGC inhibition suppressed MI-induced cardiac sympathetic hyperexcitability. Moreover, the persistent inhibition of SG-SGCs improved ventricular remodeling and dysfunction, alleviated SG and ventricular sympathetic nerve sprouting 7 days post-MI. In addition, the bulk RNA sequencing with SG and pharmacological purinergic P2Y1R (P2Y1 receptor) blockage indicated that P2Y1R/IGFBP2 (insulin-like growth factor-binding protein 2) signaling mediated the effects of SG-SGC activation on cardiac sympathetic hyperexcitability post-MI, and IGFBP2 bridged the interaction between the neurons and surrounding SGCs.</p><p><strong>Conclusions: </strong>SGC inhibition in SG rectifies cardiac sympathetic hyperactivity, stabilizes ventricular electrophysiological properties, and alleviates cardiac structural and neural remodeling post-MI, thereby preventing ventricular arrhythmias and cardiac dysfunction. Neuromodulation targeting SG-SGCs exhibits a safe and fruitful strategy for the treatment of MI.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013866"},"PeriodicalIF":9.8,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luisa C C Brant, Antônio H Ribeiro, Oseiwe B Eromosele, Marcelo M Pinto-Filho, Sandhi M Barreto, Bruce B Duncan, Martin G Larson, Emelia J Benjamin, Antonio L P Ribeiro, Honghuang Lin
{"title":"Prediction of Atrial Fibrillation From the ECG in the Community Using Deep Learning: A Multinational Study.","authors":"Luisa C C Brant, Antônio H Ribeiro, Oseiwe B Eromosele, Marcelo M Pinto-Filho, Sandhi M Barreto, Bruce B Duncan, Martin G Larson, Emelia J Benjamin, Antonio L P Ribeiro, Honghuang Lin","doi":"10.1161/CIRCEP.125.013734","DOIUrl":"https://doi.org/10.1161/CIRCEP.125.013734","url":null,"abstract":"<p><strong>Background: </strong>We aimed to refine and validate a deep neural network model from the ECG to predict atrial fibrillation (AF) risk, using samples from diverse backgrounds: the Framingham Heart Study (FHS), UK Biobank, and Estudo Longitudinal da Saúde do Adulto (ELSA-Brasil). We compared the model's performance to the clinical Cohorts for Heart and Aging Research in Genomic Epidemiology consortium (CHARGE-AF) risk score and evaluated the association with other cardiovascular outcomes.</p><p><strong>Methods: </strong>The ECG-derived deep-learning prediction of AF (ECG-AF) model was refined using 60% of FHS samples free of AF. Its performance was then tested in the remaining FHS samples, UK Biobank, and ELSA-Brasil, with discrimination assessed by the area under the receiver operating characteristic curve. The association of ECG-AF with cardiovascular outcomes was assessed using Cox proportional hazards models.</p><p><strong>Results: </strong>The study sample included 10 097 FHS participants (mean age 53±12 years; 54.9% women), 49 280 participants from the UK Biobank (mean age 64±8 years, 47.9% women), and 12 284 participants from ELSA-Brasil (mean age 53±8 years, 54.7% women). The ECG-AF model showed moderate discrimination for incident AF (area under the curve, 0.82 [95% CI, 0.80-0.84]) in the FHS, comparable to the CHARGE-AF score (area under the curve, 0.83 [95% CI, 0.81-0.85]), and incremental when combined (area under the curve, 0.85 [95% CI, 0.83-0.87]). In UK Biobank and ELSA-Brasil, combining ECG-AF and CHARGE also improved prediction. Higher ECG-AF scores were associated with increased risks of heart failure, myocardial infarction, stroke, and all-cause mortality in all 3 cohorts.</p><p><strong>Conclusions: </strong>In multinational cohort studies, the single-input ECG-AF deep neural network model demonstrated good performance in predicting AF and other cardiovascular outcomes, comparable to a multivariable clinical risk score, with improved performance when combined.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013734"},"PeriodicalIF":9.8,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mikael Björnson, Klara Wijnbladh, Anna Törnberg, Anna Svensson-Raskh, Annie Svensson, Marcus Ståhlberg, Michael Runold, Artur Fedorowski, Malin Nygren-Bonnier, Judith Bruchfeld
{"title":"Prevalence and Clinical Impact of Postural Orthostatic Tachycardia Syndrome in Highly Symptomatic Long COVID.","authors":"Mikael Björnson, Klara Wijnbladh, Anna Törnberg, Anna Svensson-Raskh, Annie Svensson, Marcus Ståhlberg, Michael Runold, Artur Fedorowski, Malin Nygren-Bonnier, Judith Bruchfeld","doi":"10.1161/CIRCEP.124.013629","DOIUrl":"10.1161/CIRCEP.124.013629","url":null,"abstract":"<p><strong>Background: </strong>The incidence of postural orthostatic tachycardia syndrome (POTS) in long COVID has been a growing concern since the first cases were reported in 2021. The aim of this study was to assess the prevalence and clinical impact of POTS in a series of well-characterized patients with long COVID.</p><p><strong>Methods: </strong>We prospectively analyzed 467 nonhospitalized, highly symptomatic (sick leave ≥50%) patients with long COVID, and studied differences in demographics and clinical assessment outcomes between those diagnosed with POTS and the remaining long COVID patients. Examinations were performed at a median of 12 months after acute COVID-19, followed by a cardiologist evaluation with 48-hour ECG, head-up tilt test, and Active Stand Test for those with clinically suspected POTS.</p><p><strong>Results: </strong>Of all long COVID patients, 143 (31%) were diagnosed with POTS, 128 (27%) did not fulfill POTS criteria, while 196 (42%) had no clinical signs of POTS. Patients with POTS were younger (mean age, 40.0 versus 44.0 versus 47.0 years, respectively; <i>P</i>≤0.001) and predominantly female (91%). They had significantly lower physical activity compared with the other 2 groups, as measured with the Frändin-Grimby scale (<i>P</i>=0.001). Heart rates during the 6-minute walk test were significantly higher in the POTS group, both during walking and at rest afterward, with a significantly shorter walking distance (448 m versus 472 m versus 509 m, respectively; <i>P</i>≤0.001). However, the distribution of symptoms showed no significant differences between the groups.</p><p><strong>Conclusions: </strong>In this cohort of predominantly younger women with highly symptomatic long COVID, POTS is common and presents with overlapping symptoms between POTS and non-POTS patients. Long COVID POTS confers lower physical activity and capacity compared with non-POTS long COVID and should be systematically assessed in this condition.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013629"},"PeriodicalIF":9.8,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of Low-Voltage-Area Ablation Is Enhanced in Patients With Advanced Left Atrial Enlargement: A Subanalysis of the SUPPRESS-AF Trial.","authors":"Masaharu Masuda, Yasuhiro Matsuda, Hiroyuki Uematsu, Hirotaka Ooka, Satoshi Kudo, Mizuki Ochi, Toshiaki Mano, Akihiro Sunaga, Nobuaki Tanaka, Tetsuya Watanabe, Hitoshi Minamiguchi, Yasuyuki Egami, Takafumi Oka, Tomoko Minamisaka, Takashi Kanda, Masato Okada, Masato Kawasaki, Koji Tanaka, Nobuhiko Makino, Hirota Kida, Shungo Hikoso, Tomoharu Dohi, Koichi Inoue, Yohei Sotomi, Yasushi Sakata","doi":"10.1161/CIRCEP.125.014210","DOIUrl":"10.1161/CIRCEP.125.014210","url":null,"abstract":"<p><strong>Background: </strong>In the randomized controlled SUPPRESS-AF trial, the efficacy of low-voltage-area (LVA) ablation was highly dependent on the degree of atrial remodeling, while the efficacy was not statistically significant in total patients. This subanalysis of the SUPPRESS-AF trial aimed to compare the efficacy of LVA ablation in patient groups classified by left atrial diameter (LAD), which is a commonly used atrial remodeling index.</p><p><strong>Methods: </strong>The SUPPRESS-AF trial included patients with persistent AF and left atrial LVAs, and compared rhythm outcomes between patients randomized to undergo pulmonary vein isolation (PVI) followed by left atrial LVA ablation group (n=170) or PVI-alone group (n=172). In this post hoc subanalysis, patients in each of the 2 randomly allocated groups were further divided into 2 groups using a median LAD of 44 mm.</p><p><strong>Results: </strong>Atrial fibrillation or atrial tachycardia recurrence-free rates did not differ between patients with LAD>44 mm and ≤44 mm (60.1% versus 53.7%; <i>P</i>=0.261). Among patients with a LAD>44 mm, the LVA ablation group demonstrated a higher atrial fibrillation or atrial tachycardia-recurrence-free rate than the PVI-alone group (62.5% versus 43.4%; <i>P</i>=0.016). In contrast, no difference in atrial fibrillation or atrial tachycardia recurrence-free rate was found between the 2 groups of patients with a LAD≤44 mm (60.8% versus 59.6%; <i>P</i>=0.986).</p><p><strong>Conclusions: </strong>The efficacy of LVA ablation in addition to PVI for the treatment of persistent AF was more pronounced in patients with a large left atrium.</p><p><strong>Registration: </strong>URL: https://www.umin.ac.jp/ctr; Unique identifier: UMIN000035940.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e014210"},"PeriodicalIF":9.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12529982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleksandar Izda, Anika Sonig, Alyson Brown, Erin Capodanno, Maria Matteo, Bryan Baranowski, Mandeep Bhargava, Thomas Callahan, Thomas J Dresing, Koji Higuchi, Ayman Hussein, Mohamed Kanj, Arshneel Kochar, Robert Koeth, Justin Lee, David Martin, Shady Nakhla, Walid Saliba, Tyler Taigen, Niraj Varma, Oussama Wazni, Pasquale Santangeli, Mina K Chung, Jakub Sroubek
{"title":"Prevalence and Clinical Course of Suspected Acute Pericarditis Following Atrial Pulsed-Field Ablation.","authors":"Aleksandar Izda, Anika Sonig, Alyson Brown, Erin Capodanno, Maria Matteo, Bryan Baranowski, Mandeep Bhargava, Thomas Callahan, Thomas J Dresing, Koji Higuchi, Ayman Hussein, Mohamed Kanj, Arshneel Kochar, Robert Koeth, Justin Lee, David Martin, Shady Nakhla, Walid Saliba, Tyler Taigen, Niraj Varma, Oussama Wazni, Pasquale Santangeli, Mina K Chung, Jakub Sroubek","doi":"10.1161/CIRCEP.125.014263","DOIUrl":"https://doi.org/10.1161/CIRCEP.125.014263","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e014263"},"PeriodicalIF":9.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145147798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christina Y Miyake, Dania Kallas, Sara B Stephens, Oliver M Moore, Xander H T Wehrens, Peter S Fischbach, Martin J LaPage, Andrew P Landstrom, Ian H Law, Allison C Hill, Prince J Kannankeril, Frank A Fish, Taylor S Howard, Santiago O Valdes, Tam Dam Pham, Jeffrey J Kim, Santokh Dhillon, Christopher L Johnsrude, Ulrich Krause, Georgia Sarquella-Brugada, Peter Kubus, Terezia Tavacova, Sit-Yee Kwok, Susan P Etheridge, Svjetlana Tisma-Dupanovic, Adam C Kean, Andrew D Krahn, Mohammed Ebrahim, Joseph Atallah, Anne Fournier, Anjan S Batra, Ming-Lon Young, James Perry, Joshua R Kovach, Anna N Kamp, Bradley C Clark, Erick Jimenez, Fatme Charafeddine, Robert M Hamilton, Seshadri Balaji, Shubhayan Sanatani
{"title":"Intellectual and Neurodevelopmental Delays in Pediatric Catecholaminergic Polymorphic Ventricular Tachycardia: Distinct Characteristics and a More Malignant Neurocardiac Phenotype.","authors":"Christina Y Miyake, Dania Kallas, Sara B Stephens, Oliver M Moore, Xander H T Wehrens, Peter S Fischbach, Martin J LaPage, Andrew P Landstrom, Ian H Law, Allison C Hill, Prince J Kannankeril, Frank A Fish, Taylor S Howard, Santiago O Valdes, Tam Dam Pham, Jeffrey J Kim, Santokh Dhillon, Christopher L Johnsrude, Ulrich Krause, Georgia Sarquella-Brugada, Peter Kubus, Terezia Tavacova, Sit-Yee Kwok, Susan P Etheridge, Svjetlana Tisma-Dupanovic, Adam C Kean, Andrew D Krahn, Mohammed Ebrahim, Joseph Atallah, Anne Fournier, Anjan S Batra, Ming-Lon Young, James Perry, Joshua R Kovach, Anna N Kamp, Bradley C Clark, Erick Jimenez, Fatme Charafeddine, Robert M Hamilton, Seshadri Balaji, Shubhayan Sanatani","doi":"10.1161/CIRCEP.124.013437","DOIUrl":"https://doi.org/10.1161/CIRCEP.124.013437","url":null,"abstract":"<p><strong>Background: </strong>Marked intellectual and neurodevelopmental delay (INDD) was noted in 6 unrelated patients diagnosed with <i>RYR2</i>-related catecholaminergic polymorphic ventricular tachycardia (CPVT) from a single center. Patients exhibited similar distinct phenotypic features not previously described. We aimed to determine the prevalence of INDD in CPVT, compare clinical characteristics between patients with CPVT with and without INDD, and investigate the possibility of a unique neurocardiac CPVT phenotype.</p><p><strong>Methods: </strong>Retrospective combined review of patients with <i>RYR2</i>-related CPVT diagnosed ≤18 years with and without INDD from a single center and the International Pediatric CPVT Registry. Patients with hypoxic ischemic insult were excluded unless INDD preceded injury.</p><p><strong>Results: </strong>Among a total of 168 patients, INDD was reported in 19 (11.3% [95% CI, 7.0%-17.1%]). When compared with cases without INDD, patients with INDD exhibited distinct features including (1) younger age at onset of symptoms (median 7.0 versus 10.0 years; <i>P</i>=0.04); (2) higher frequency of atrial tachyarrhythmias (84.2% versus 16.3%, <i>P</i><0.001); (3) atrial or ventricular tachycardia without adrenergic stimulation (81.3% versus 2.2%, <i>P</i><0.001, 31.6% versus 4.5%, <i>P</i>=0.001 respectively); (4) cardiac structural changes or systolic dysfunction (36.8% versus 1.3%, <i>P</i><0.001); and (5) higher incidence of cardiac arrest or sudden death after diagnosis (26.3% versus 2.7%, <i>P</i>=0.001). INDD-related <i>RYR2</i> genetic variants clustered within the central and channel domains and may be specific to certain variants.</p><p><strong>Conclusions: </strong>This study demonstrates a wider spectrum of <i>RYR2</i>-related disease, with a subset associated with extracardiac manifestations. Certain <i>RYR2</i> variants may lead to a neurocardiac phenotype with distinct features that are important to recognize, as these patients may be at higher risk.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013437"},"PeriodicalIF":9.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashwin Bhaskaran, Tejas Deshmukh, Dinesh Selvakumar, Richard Bennett, Samual Turnbull, Timothy G Campbell, Yasuhito Kotake, Michael A Barry, Juntang Lu, Lachlan Pearson, Eddy Kizana, James J H Chong, Saurabh Kumar
{"title":"Comparison of Extrastimulus Pacing Strategies for the Detection of Arrhythmogenic Substrate for Ventricular Tachycardia: Insights From a Porcine Ischemia-Reperfusion Injury Model.","authors":"Ashwin Bhaskaran, Tejas Deshmukh, Dinesh Selvakumar, Richard Bennett, Samual Turnbull, Timothy G Campbell, Yasuhito Kotake, Michael A Barry, Juntang Lu, Lachlan Pearson, Eddy Kizana, James J H Chong, Saurabh Kumar","doi":"10.1161/CIRCEP.125.013902","DOIUrl":"https://doi.org/10.1161/CIRCEP.125.013902","url":null,"abstract":"<p><strong>Background: </strong>Multiple extrastimulus (ES) pacing protocols exist for ventricular substrate mapping. Despite being increasingly adopted in clinical practice, direct protocol comparisons have been limited. This study aims to compare the substrate delineation and mapping efficiency of right ventricular pacing+ES (RVp+ES) and sensed ES pacing strategies in a large animal ischemia-reperfusion injury model.</p><p><strong>Methods: </strong>Four swine underwent 90-minute balloon occlusion of the mid-left anterior descending artery, followed by late gadolinium-enhanced cardiac magnetic resonance between days 30 and 58 and invasive electroanatomic mapping. Late gadolinium-enhanced cardiac magnetic resonances were segmented for scar topography and border zone channel geometry.</p><p><strong>Results: </strong>Sensed ES substrate maps had greater point density (12.90±4.20 pts/cm<sup>2</sup> versus 5.75±0.52 pts/cm<sup>2</sup>; <i>P</i>=0.032) and faster acquisition (113.71±22.38 s/pt per cm<sup>2</sup> versus 228.57±77.30 s/pt per cm<sup>2</sup>; <i>P</i>=0.027) than RVp+ES. Despite this, RVp+ES substrate maps had greater uncovering of split potentials within border zone channels (76.5% [15.4%-95.5%] versus 16.7% [0%-52.9%]; <i>P</i>=0.028), higher sensitivity (53% versus 30%), and similarly high specificity (91% versus 93%) than sensed ES, as well as better visual correlation on decrement-evoked potential maps. Bipolar voltage in sinus rhythm and RVp did not reliably predict tissue response to ES, with 46% to 57% of split potentials within border zone channels arising from seemingly normal voltage (≥1.5 mV).</p><p><strong>Conclusions: </strong>RVp+ES is more sensitive than sensed ES and highly specific for the detection of late gadolinium-enhanced cardiac magnetic resonance border zone channels postmyocardial infarct.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013902"},"PeriodicalIF":9.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145136645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dongjuan Wang, Longfu Jiang, Jiabo Shen, Hengdong Li
{"title":"Characteristics of Different Ventricular Electrogram Morphologies in Selective Left Bundle Branch Pacing.","authors":"Dongjuan Wang, Longfu Jiang, Jiabo Shen, Hengdong Li","doi":"10.1161/CIRCEP.125.013879","DOIUrl":"10.1161/CIRCEP.125.013879","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013879"},"PeriodicalIF":9.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12442774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}