Steven A Muller, Babken Asatryan, Brittney Murray, Crystal Tichnell, Moniek G P J Cox, Ahmad S Amin, Sing-Chien Yap, Alessio Gasperetti, Richard T Carrick, Julia Cadrin-Tourigny, Marish I F J Oerlemans, Hugh Calkins, J Peter van Tintelen, Cynthia A James, Anneline S J M Te Riele
{"title":"Performance of ARVC Risk Calculators in (Likely) Pathogenic Plakophilin-2 Variant Carriers Without Definite ARVC Diagnosis.","authors":"Steven A Muller, Babken Asatryan, Brittney Murray, Crystal Tichnell, Moniek G P J Cox, Ahmad S Amin, Sing-Chien Yap, Alessio Gasperetti, Richard T Carrick, Julia Cadrin-Tourigny, Marish I F J Oerlemans, Hugh Calkins, J Peter van Tintelen, Cynthia A James, Anneline S J M Te Riele","doi":"10.1161/CIRCEP.124.013144","DOIUrl":"https://doi.org/10.1161/CIRCEP.124.013144","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013144"},"PeriodicalIF":9.1,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Discrimination Between Anterior and Posterior Left Atrial Roof Area Ablation by a Cryoballoon.","authors":"Tetsuma Kawaji, Takanori Aizawa, Misaki Naka, Saki Yamano, Bao Bingyuan, Shun Hojo, Yuji Tezuka, Shintaro Matsuda, Masashi Kato, Takafumi Yokomatsu, Shinji Miki","doi":"10.1161/CIRCEP.124.013093","DOIUrl":"https://doi.org/10.1161/CIRCEP.124.013093","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013093"},"PeriodicalIF":9.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iwanari Kawamura, Rahul Bhardwaj, Assaf Govari, Christopher Beeckler, Jennifer Maffre, Salman Farshchi-Heydari, Benjamin Manacop, Tushar Sharma, Vivek Y Reddy, Jacob Koruth
{"title":"Coronary Involvement With Pulsed Field Ablation and Radiofrequency Ablation: Preclinical Insights.","authors":"Iwanari Kawamura, Rahul Bhardwaj, Assaf Govari, Christopher Beeckler, Jennifer Maffre, Salman Farshchi-Heydari, Benjamin Manacop, Tushar Sharma, Vivek Y Reddy, Jacob Koruth","doi":"10.1161/CIRCEP.124.013161","DOIUrl":"https://doi.org/10.1161/CIRCEP.124.013161","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013161"},"PeriodicalIF":9.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luisa Freyer, Peter Spielbichler, Lukas von Stülpnagel, Aresa Krasniqi, Maximilian Wörndl, Lukas Tenbrink, Laura Elisa Villegas Sierra, Maria F Vogl, Lauren E Sams, Ann-Kathrin Mayer, Michael Schreinlechner, Elodie Eiffener, Annika Schneidewind, Mathias Klemm, Steffen Massberg, Axel Bauer, Konstantinos D Rizas
{"title":"Impact of Age on Smartphone-Based Screening for Atrial Fibrillation: A Prespecified Subgroup Analysis of the eBRAVE-AF Trial.","authors":"Luisa Freyer, Peter Spielbichler, Lukas von Stülpnagel, Aresa Krasniqi, Maximilian Wörndl, Lukas Tenbrink, Laura Elisa Villegas Sierra, Maria F Vogl, Lauren E Sams, Ann-Kathrin Mayer, Michael Schreinlechner, Elodie Eiffener, Annika Schneidewind, Mathias Klemm, Steffen Massberg, Axel Bauer, Konstantinos D Rizas","doi":"10.1161/CIRCEP.124.013293","DOIUrl":"https://doi.org/10.1161/CIRCEP.124.013293","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013293"},"PeriodicalIF":9.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luigi Pannone, Domenico Giovanni Della Rocca, Pasquale Vergara, Antonio Sorgente, Alvise Del Monte, Giampaolo Vetta, Maria Cespon Fernandez, Giacomo Talevi, Ivan Eltsov, Paul-Adrian Calburean, Ingrid Overeinder, Gezim Bala, Alexandre Almorad, Erwin Ströker, Gudrun Pappaert, Juan Sieira, Thomy de Ravel, Sonia Van Dooren, Ali Gharaviri, Mark La Meir, Pedro Brugada, Gian Battista Chierchia, Andrea Sarkozy, Carlo de Asmundis
{"title":"In Vivo Mapping of Human Ventricular Fibrillation in Brugada Syndrome: The Role of Repolarization Heterogeneity.","authors":"Luigi Pannone, Domenico Giovanni Della Rocca, Pasquale Vergara, Antonio Sorgente, Alvise Del Monte, Giampaolo Vetta, Maria Cespon Fernandez, Giacomo Talevi, Ivan Eltsov, Paul-Adrian Calburean, Ingrid Overeinder, Gezim Bala, Alexandre Almorad, Erwin Ströker, Gudrun Pappaert, Juan Sieira, Thomy de Ravel, Sonia Van Dooren, Ali Gharaviri, Mark La Meir, Pedro Brugada, Gian Battista Chierchia, Andrea Sarkozy, Carlo de Asmundis","doi":"10.1161/CIRCEP.124.013290","DOIUrl":"10.1161/CIRCEP.124.013290","url":null,"abstract":"<p><strong>Background: </strong>Brugada syndrome (BrS) is associated with ventricular fibrillation (VF). Different VF mechanisms have been described, and repolarization gradients were associated with VF in a BrS model. The aim of this study is to map VF in BrS with ECG imaging. Furthermore, spatial correlation between sinus rhythm maps and VF maps was evaluated.</p><p><strong>Methods: </strong>Inclusion criteria were (1) BrS diagnosis and (2) VF mapped with ECG imaging during right ventricle outflow tract ablation. VF mechanism was classified into (1) rotational, (2) focal, and (3) irregular. For comparison, 6 controls were enrolled. The following sinus rhythm maps were performed: activation, recovery time, and activation-recovery interval time. Spatial overlap between steep repolarization gradients (cliffs) at recovery time and activation-recovery interval time maps and initiating VF rotational activity was evaluated with photogrammetry.</p><p><strong>Results: </strong>A total of 28 VF maps in 21 patients with BrS were analyzed. In the first ≈7 seconds of VF, rotational, focal, and irregular mechanisms were found. In 19 patients with BrS (90.5%) and none of the controls, a right ventricle outflow tract repolarization cliff only was found. In all these patients, the singularity point of the first initiating rotational VF activity spatially overlapped with the right ventricle outflow tract cliff. Abolition of right ventricle outflow tract repolarization cliffs was confirmed in all but 2 patients (94.3%). In one patient with recurrence, VF was mapped on the anterior right ventricle over a cliff that was not targeted at the first ablation procedure.</p><p><strong>Conclusions: </strong>In patients with BrS, repolarization heterogeneity has a critical role in VF. Repolarization cliffs might be a therapeutic target in VF ablation.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013290"},"PeriodicalIF":9.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bruce S Stambler, Benoit Coutu, James E Ip, Blandine Mondésert, A Shekhar Pandey, Philip T Sager, Doug Wight, Francis Plat, Silvia Shardonofsky, David B Bharucha, A John Camm
{"title":"Self-Administered Etripamil Nasal Spray Relieved Symptoms, Decreased Heart Rate, and Reduced Medical Interventions During Atrioventricular Nodal-Dependent Paroxysmal Supraventricular Tachycardia.","authors":"Bruce S Stambler, Benoit Coutu, James E Ip, Blandine Mondésert, A Shekhar Pandey, Philip T Sager, Doug Wight, Francis Plat, Silvia Shardonofsky, David B Bharucha, A John Camm","doi":"10.1161/CIRCEP.123.011681","DOIUrl":"10.1161/CIRCEP.123.011681","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e011681"},"PeriodicalIF":9.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142726535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Balaram Krishna Hanumanthu, Jason Wink, Gustavo Guandalini, Francis E Marchlinski, David S Frankel, Timothy M Markman
{"title":"Tumescent Local Anesthesia During Cardiac Implantable Electronic Device Implantation to Reduce Postoperative Pain.","authors":"Balaram Krishna Hanumanthu, Jason Wink, Gustavo Guandalini, Francis E Marchlinski, David S Frankel, Timothy M Markman","doi":"10.1161/CIRCEP.124.013168","DOIUrl":"10.1161/CIRCEP.124.013168","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013168"},"PeriodicalIF":9.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142726549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulsed Field Ablation of Paroxysmal Supraventricular Tachycardia: A Prospective Multicenter Single-Arm Study in China.","authors":"Fanghui Li, Aobo Gong, Hongde Hu, Kaijun Cui, Qing Yang, Xiaobo Pu, Shi Chen, Jian Jiang, Hua Fu, Hanxiong Liu, Yuehui Yin, Qiangsun Zheng, Maoqin Shu, Chun Gui, Jian Xu, Pingzhen Yang, Zhiyu Ling, Hongzhi Wang, Tingting Yang, Rongzheng Yue, Jinnian Gao, Xiaolin Zhu, Tiancai Shi, Wentao Li, Xianjin Hu, Yao Tong, Qing Zhang, Rui Zeng","doi":"10.1161/CIRCEP.124.013206","DOIUrl":"10.1161/CIRCEP.124.013206","url":null,"abstract":"<p><strong>Background: </strong>Pulsed field ablation (PFA) has gained attention in cardiac electrophysiology, but data on its application to paroxysmal supraventricular tachycardia are limited. This study aimed to assess the feasibility and safety of PFA and its combination with radiofrequency ablation for treating paroxysmal supraventricular tachycardia.</p><p><strong>Methods: </strong>A prospective, multicenter, single-arm study was conducted across 8 centers in China. Patients with atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia, or Wolff-Parkinson-White syndrome underwent ablation using a focal point dual-mode PFA/radiofrequency ablation catheter. PFA was used to achieve acute ablation success, with consolidation using PFA for atrioventricular nodal reentrant tachycardia or near-His accessory pathways and radiofrequency ablation for far-His accessory pathways. Primary and secondary end points were acute ablation success and 180-day follow-up success, respectively.</p><p><strong>Results: </strong>A total of 158 patients (77 with atrioventricular nodal reentrant tachycardia, 63 with atrioventricular reentrant tachycardia, 16 with Wolff-Parkinson-White, and 2 with both atrioventricular nodal reentrant tachycardia and atrioventricular reentrant tachycardia) completed the trial. Acute ablation was successful in 157 patients (99.37%). The skin-to-skin procedure time was 89.9±35.5 min. The median number of PFA discharges was 12 (8-19) with a median effective PFA discharge time of 4.6 (3.2-6.4) ms. Five patients (4 with atrioventricular reentrant tachycardia and 1 with Wolff-Parkinson-White syndrome) experienced paroxysmal supraventricular tachycardia recurrence during the 180-day follow-up period. One patient had a transient first-degree atrioventricular block resolving in 12 hours, and one patient had a transient third-degree atrioventricular block resolving in 24 hours. No permanent atrioventricular block or other adverse events occurred during the ablation procedure or 180-day follow-up period.</p><p><strong>Conclusions: </strong>PFA demonstrated the feasibility of the treatment of SVT. Reversible first- and third-degree atrioventricular blocks were observed following ablation in one patient each. The preliminary results indicated the safety and feasibility of a combination of PFA and radiofrequency ablation treatment for atrioventricular accessory pathways although it is impossible to determine the relative contribution of PFA.</p>","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013206"},"PeriodicalIF":9.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lars Mattison, Atul Verma, Khaldoun G Tarakji, Daniel C Sigg
{"title":"Hemolysis After Pulsed Field Ablation: The Role of Dose and Contact in an Acute Porcine Model.","authors":"Lars Mattison, Atul Verma, Khaldoun G Tarakji, Daniel C Sigg","doi":"10.1161/CIRCEP.124.013317","DOIUrl":"10.1161/CIRCEP.124.013317","url":null,"abstract":"","PeriodicalId":10319,"journal":{"name":"Circulation. Arrhythmia and electrophysiology","volume":" ","pages":"e013317"},"PeriodicalIF":9.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142726510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}