Other Topics Engineering Research eJournal最新文献_第10页

SQptr a Proposed Set of Guidelines for Setting Up Proceduring for Enabling Solution Development SQptr一套建议的指导方针，以建立可行的解决方案开发程序

Other Topics Engineering Research eJournal Pub Date : 2019-12-04 DOI: 10.2139/ssrn.3497973

Sidharth Mallik

引用次数: 0

A Glance on the Estimation of Cobb-Douglas Production Functional Model 柯布-道格拉斯生产函数模型估计概论

Other Topics Engineering Research eJournal Pub Date : 2019-12-04 DOI: 10.1063/1.5135242

Dr Ranadheer Donthi

引用次数: 10

How 3d Transition Metal Elements Determine the Oxygen Evolution Activity in Ni(OH) 2 Matrix 三维过渡金属元素如何决定Ni(OH) 2基体中的析氧活性

Other Topics Engineering Research eJournal Pub Date : 2019-12-03 DOI: 10.2139/ssrn.3497024

Yuhai Dou, Chun He, Lei Zhang, M. Al‐Mamun, Haipeng Guo, Wenchao Zhang, Qingbing Xia, Jiantie Xu, Lixue Jiang, Yun Wang, Porun Liu, Xiao‐Ming Chen, H. Yin, Huijun Zhao

引用次数: 0

Review of Experimental and Computational Analysis of Coaxial H-Savonius Vertical Axis Wind Rotor 同轴H-Savonius垂直轴风转子实验与计算分析综述

Other Topics Engineering Research eJournal Pub Date : 2019-11-30 DOI: 10.2139/ssrn.3495796

P. Bhadra, S. Alam, B. Debnath, D. Sarkar, Dr. A.R. Sengupta

引用次数: 0

Analysing Demand and Supply Projects on a Mine Compressed Air System 某矿山压缩空气系统供需方案分析

Other Topics Engineering Research eJournal Pub Date : 2019-11-26 DOI: 10.2139/ssrn.3637840

W. Shaw, J. Marais, J. V. van Laar, C. Cilliers, J. Stols

{"title":"Analysing Demand and Supply Projects on a Mine Compressed Air System","authors":"W. Shaw, J. Marais, J. V. van Laar, C. Cilliers, J. Stols","doi":"10.2139/ssrn.3637840","DOIUrl":"https://doi.org/10.2139/ssrn.3637840","url":null,"abstract":"The cost of electricity in South Africa has been increasing at rates that are significantly higher than inflation. Eskom most recently proposed increases of up to 15%. Various methods have already been introduced to reduce energy consumption at different types of mining operations. Efficient energy use has been and will continuously be a big focus going into the 4th industrial revolution (4IR). As found from literature, compressed air systems are one of the largest energy consumers at typical South African mines. This paper focuses on improvements on mine compressed air systems and limiting factors of reducing said energy consumption on an already optimized mine. Through literature, it was found that specific energy can be used to analyse compressors. This method was used to characterise compressor systems and isolate areas where improvement projects may have a significant effect on a given mine’s compressor energy consumption. The methods for proposing and implementing further projects are discussed with illustration thereof as well as the corresponding effects. Current initiatives, if sustained may result, in as much as R4.5 million per annum in energy savings. A properly analysed system combined with well tailored, investigated and implemented projects can lead to further energy savings of up to R20 million per annum.","PeriodicalId":102139,"journal":{"name":"Other Topics Engineering Research eJournal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122914381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trnsys Validation of a 1.5 Axis Tracking Concentrated Solar Photovoltaic Thermal System Trnsys 1.5轴跟踪聚光太阳能光伏热系统的验证

Other Topics Engineering Research eJournal Pub Date : 2019-11-26 DOI: 10.2139/ssrn.3658921

N. Nteka, K. Kanyarusoke

引用次数: 0

TPGS-Based Dual-Targeted Crosslinked Micelles to Reverse Chemoresistance 基于tpgs的双靶向交联胶束逆转化学耐药

Other Topics Engineering Research eJournal Pub Date : 2019-11-20 DOI: 10.2139/ssrn.3490424

Li Li, Tao Liu, Zhe-Yi Zhang, Guan-Hai Wang

{"title":"TPGS-Based Dual-Targeted Crosslinked Micelles to Reverse Chemoresistance","authors":"Li Li, Tao Liu, Zhe-Yi Zhang, Guan-Hai Wang","doi":"10.2139/ssrn.3490424","DOIUrl":"https://doi.org/10.2139/ssrn.3490424","url":null,"abstract":"D-α-Tocopherol polyethylene glycol succinate (TPGS) has been widely applied in drug delivery systems (DDS) to reverse tumor multidrug resistance (MDR) caused by overexpression of P-glycoprotein (P-gp). However its capability of inhibiting overexpression of P-gp is still limited due to poor penetration and premature drug release. Herein, the dual-targeted CMs based on charge reversal cell penetration peptide (cTAT) functionalized TPGS (cTAT-TPGS) and folic acid functionalized polypeptide (Folic acid-PEG-b-poly(Aspartic-Lipoic acid), FA-PPAL) were designed to reverse chemoresistance and improve chemotherapeutic efficacy. TAT was shielded by fatty acids and polypeptide introduced disulfide bonds. The CMs could keep stability with minimal drug leakage in blood circulation, whereas charge of TAT transform positive to improve the penetration and rapid dissociation of CMs to control drug release in low acidic and reductive environment of cancer cells. Furthermore, DOX achieved high accumulation in drug resistant cancer cells and directly released inside nucleus, leading to anti-MDR abilities and effective inhibition of tumor growth. Moreover, the DOX-loaded CMs showed excellent biosafety, especially for the myocardium tissue. Overall, this novel strategy provided an effective platform for drug target delivery and reversal of MDR.","PeriodicalId":102139,"journal":{"name":"Other Topics Engineering Research eJournal","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128634387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multi-Modal Dynamic Pricing 多式联运动态定价

Other Topics Engineering Research eJournal Pub Date : 2019-11-18 DOI: 10.2139/ssrn.3489355

Yining Wang, Boxiao Chen, D. Simchi-Levi

{"title":"Multi-Modal Dynamic Pricing","authors":"Yining Wang, Boxiao Chen, D. Simchi-Levi","doi":"10.2139/ssrn.3489355","DOIUrl":"https://doi.org/10.2139/ssrn.3489355","url":null,"abstract":"We consider a stylistic question of dynamic pricing of a single product with demand learning. The candidate prices belong to a wide range of price interval, and the modeling of the demand functions is nonparametric in nature, imposing only smoothness regularity conditions. One important aspect of our modeling is the possibility of the expected reward function to be non-convex and indeed multi-modal, which leads to many conceptual and technical challenges. Our proposed algorithm is inspired by both the Upper-Confidence-Bound (UCB) algorithm for multi-armed bandit and the Optimism-in-Face-of-Uncertainty (OFU) principle arising from linear contextual bandits. Through rigorous regret analysis, we demonstrate that our proposed algorithm achieves optimal worst-case regret over a wide range of smooth function classes. More specifically, for k-times smooth functions and T selling periods, the regret of our propose algorithm is O(T^{(k+1)/(2k+1)}), which is shown to be optimal via information theoretical lower bounds. We also show that in special cases such as strongly concave or infinitely smooth reward functions, our algorithm achieves an O(sqrt{T}) regret matching optimal regret established in previous works. Finally, we present numerical results which verify the effectiveness of our method in numerical simulations.","PeriodicalId":102139,"journal":{"name":"Other Topics Engineering Research eJournal","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124385958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

The Advent of Technology and its Impact on the Society 技术的出现及其对社会的影响

Other Topics Engineering Research eJournal Pub Date : 2019-11-14 DOI: 10.2139/ssrn.3598962

Sriya Shubhalaxmi Mishra

{"title":"The Advent of Technology and its Impact on the Society","authors":"Sriya Shubhalaxmi Mishra","doi":"10.2139/ssrn.3598962","DOIUrl":"https://doi.org/10.2139/ssrn.3598962","url":null,"abstract":"Today technology has occupied such an important place in the modern society that it is next to impossible to imagine life without it. A plethora of technological advancements take place everyday, so much that it is almost impossible to keep a track of all of them. While it has both its advantages and disadvantages, the disadvantages would be the centre of discussion for this research paper. Technology in the present day modern society has a lot of impact on the way the society is conducted. To substantiate the present day scenario various theories, research findings of great thinkers and philosophers have been taken into account. Arguably, some of these technological advancements have increased stress levels and isolation within the society. There is no denying that technology has its positive attributes, but when looking at the way it has impacted on the society, then it is safe to state that technology has a negative impact too. Technology saw the boom in its usage for the first time during the industrial revolution when the capitalism was on the rise. Then, technology played the role of mobilizing people and increase in the production. But at the same time it also negatively impacted the cottage industries and low scale outlets, forced them to close, reduced the employment opportunities because what was done by human beings earlier was now done by the machines.","PeriodicalId":102139,"journal":{"name":"Other Topics Engineering Research eJournal","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116757310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Strut Design of Deep Excavation: Theory and Solved Example 深基坑支护设计:理论与算例

Other Topics Engineering Research eJournal Pub Date : 2019-11-13 DOI: 10.2139/ssrn.3486532

M. Bahrami

引用次数: 1